Published in Science on April 14, 1967
Enduring behavioral changes in rats with experimental phenylketonuria. Proc Natl Acad Sci U S A (1972) 0.94
Liver phenylalanine hydroxylase activity in relation to blood concentrations of tyrosine and phenylalanine in the rat. Biochem J (1972) 0.92
Comparison of alpha-methylphenylalanine and p-chlorophenylalanine as inducers of chronic hyperphenylalaninaemia in developing rats. Biochem J (1978) 0.90
Effect of glucagon on phenylalanine metabolism and phenylalanine-degrading enzymes in the rat. Biochem J (1974) 0.85
beta-2-Thienyl-DL-alanine as an inhibitor of phenylalanine hydroxylase and phenylalanine intestinal transport. Biochem J (1979) 0.84
Parachlorophenylalanine treatment in carcinoid syndrome. Br Med J (1970) 0.83
The regulation of phenylalanine hydroxylase in rat tissues in vivo. The maintenance of high plasma phenylalanine concentrations in suckling rats: a model for phenylketonuria. Biochem J (1976) 0.81
The enduring behavioral changes in rats with experimental phenylketonuria. Proc Natl Acad Sci U S A (1974) 0.80
Demonstration and distribution of phenylethanolamine in brain and other tissues. Proc Natl Acad Sci U S A (1973) 0.78
Effects of p-chlorophenylalanine and alpha-methylphenylalanine on amino acid uptake and protein synthesis in mouse neuroblastoma cells. Biochem J (1978) 0.77
Distribution and metabolism of phenylalanine and tyrosine during tualraemia in the rat. Biochem J (1974) 0.76
Fluorescamine: a reagent for assay of amino acids, peptides, proteins, and primary amines in the picomole range. Science (1972) 11.71
Fluorometric assay of proteins in the nanogram range. Arch Biochem Biophys (1973) 7.81
Algebraic reconstruction techniques (ART) for three-dimensional electron microscopy and x-ray photography. J Theor Biol (1970) 6.86
Sporadic cases of hemorrhagic colitis associated with Escherichia coli O157:H7. Clinical, epidemiologic, and bacteriologic features. Ann Intern Med (1984) 6.54
Hydroxylation-induced migration: the NIH shift. Recent experiments reveal an unexpected and general result of enzymatic hydroxylation of aromatic compounds. Science (1967) 3.60
A multifactorial system for equitable selection of cadaver kidney recipients. JAMA (1987) 3.01
Automatic Monitoring of primary amines in preparative column effluents with fluorescamine. Anal Biochem (1975) 2.88
Different training procedures recruit either one or two critical periods for contextual memory consolidation, each of which requires protein synthesis and PKA. Learn Mem (1999) 2.72
Formation of hydroxyproline in collagen. Science (1966) 2.68
Prolyl hydroxylase. Adv Enzymol Relat Areas Mol Biol (1974) 2.61
Molecular cloning establishes proenkephalin as precursor of enkephalin-containing peptides. Nature (1982) 2.53
A randomized trial of primary liver transplantation under immunosuppression with FK 506 vs cyclosporine. Transplant Proc (1991) 2.49
1,2-naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene. Biochemistry (1970) 2.47
Loss of DNA mismatch repair in acquired resistance to cisplatin. Cancer Res (1996) 2.37
Clinical course after liver transplantation in patients with sarcoidosis. Ann Intern Med (1993) 2.29
Amino acid analysis with fluorescamine at the picomole level. Arch Biochem Biophys (1973) 2.23
Endoscopic sclerotherapy compared with percutaneous transjugular intrahepatic portosystemic shunt after initial sclerotherapy in patients with acute variceal hemorrhage. A randomized, controlled trial. Ann Intern Med (1997) 2.17
Photometric assay of dopamine- -hydroxylase activity in human blood. Clin Chem (1972) 2.14
Morphometric and electron-microscopic analyses of the effects of gonadotropin-releasing hormone agonists on uterine leiomyomas. Arch Pathol Lab Med (1998) 2.11
One hundred ten consecutive primary orthotopic liver transplants under FK 506 in adults. Transplant Proc (1991) 2.10
Vascular endothelial growth factor(165) gene transfer augments circulating endothelial progenitor cells in human subjects. Circ Res (2000) 2.04
A method for immediate visualization of proteins in acrylamide gels and its use for preparation of antibodies to enzymes. Anal Biochem (1969) 1.92
Micromethods for induction and assay of mouse mixed lymphocyte reactions and cytotoxicity. Eur J Immunol (1976) 1.90
Isolation and characterization of the opioid peptides from rat pituitary: beta-lipotropin. Proc Natl Acad Sci U S A (1977) 1.86
An about 50,000-dalton protein in adrenal medulla: a common precursor of [Met]- and [Leu]enkephalin. Science (1980) 1.81
BICAV: a block-iterative parallel algorithm for sparse systems with pixel-related weighting. IEEE Trans Med Imaging (2001) 1.79
Serotonin, Norepinephrine, and Related Compounds in Bananas. Science (1958) 1.75
Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts. Mol Cell (1999) 1.74
Cloning and sequencing of human intestinal alkaline phosphatase cDNA. Proc Natl Acad Sci U S A (1987) 1.74
Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor. J Cell Biol (1981) 1.72
Collagen chain formation and peptidyl proline hydroxylation in monolayer tissue cultures of L-929 fibroblasts. Arch Biochem Biophys (1969) 1.71
CT in patients with scirrhous carcinoma of the GI tract: imaging findings and value for tumor detection and staging. AJR Am J Roentgenol (1995) 1.68
Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2. J Pharmacol Exp Ther (2001) 1.65
Aspartic acid-484 of nascent placental alkaline phosphatase condenses with a phosphatidylinositol glycan to become the carboxyl terminus of the mature enzyme. Proc Natl Acad Sci U S A (1988) 1.64
Expression cloning of a Na(+)-independent neutral amino acid transporter from rat kidney. Proc Natl Acad Sci U S A (1992) 1.64
Phosphatidylinositol glycan (PI-G) anchored membrane proteins. Amino acid requirements adjacent to the site of cleavage and PI-G attachment in the COOH-terminal signal peptide. J Biol Chem (1992) 1.64
Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles. J Pharmacol Exp Ther (1999) 1.63
Putative enkephalin precursors in bovine adrenal medulla. Biochem Biophys Res Commun (1979) 1.63
Selectivity of the cleavage/attachment site of phosphatidylinositol-glycan-anchored membrane proteins determined by site-specific mutagenesis at Asp-484 of placental alkaline phosphatase. Proc Natl Acad Sci U S A (1990) 1.62
Regulation of the differentiation of PC12 pheochromocytoma cells. Environ Health Perspect (1989) 1.62
Comparison of beta-adrenergic agents delivered by nebulizer vs metered dose inhaler with InspirEase in hospitalized asthmatic patients. Chest (1988) 1.62
Orthotopic liver transplantation for alcoholic liver disease. Hepatology (1990) 1.61
Liver transplantation for polycystic liver disease. Arch Surg (1990) 1.61
Inhibitors of purified beef adrenal tyrosine hydroxylase. Biochem Pharmacol (1965) 1.60
Increased synthesis of norepinephrine and epinephrine in the intact rat during exercise and exposure to cold. J Pharmacol Exp Ther (1966) 1.58
The role of arene oxide-oxepin systems in the metabolism of aromatic substrates. 3. Formation of 1,2-naphthalene oxide from naphthalene by liver microsomes. J Am Chem Soc (1968) 1.58
The effect of fibroblast growth factor on PC12 cells. J Neurosci (1985) 1.58
Survival from primary breast cancer after routine clinical use of mammography. Breast J (2002) 1.56
Preparation and properties of a homogeneous aromatic L-amino acid decarboxylase from hog kidney. Arch Biochem Biophys (1970) 1.55
A new class of tyrosine hydroxylase inhibitors and a simple assay of inhibition in vivo. Biochem Pharmacol (1967) 1.54
Orthotopic liver transplantation for acute and subacute hepatic failure in adults. Hepatology (1987) 1.53
COOH-terminal requirements for the correct processing of a phosphatidylinositol-glycan anchored membrane protein. J Biol Chem (1988) 1.52
Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: a systematic review. BJOG (2014) 1.49
Purification of nerve growth factor antibodies by affinity chromatography. J Neurochem (1976) 1.49
Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells. Clin Cancer Res (1997) 1.47
Isolation of the opioid heptapeptide Met-enkephalin [Arg6,Phe7] from bovine adrenal medullary granules and striatum. Proc Natl Acad Sci U S A (1979) 1.47
Isolation and characterization of the opioid peptides from rat pituitary: beta-endorphin. Proc Natl Acad Sci U S A (1977) 1.47
Purification and properties of collagen proline hydroxylase from newborn rat skin. Arch Biochem Biophys (1970) 1.46
The action of adenosine analogs on PC12 cells. J Neurochem (1981) 1.44
Expression of active, membrane-bound human placental alkaline phosphatase by transfected simian cells. Proc Natl Acad Sci U S A (1987) 1.44
Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. Br J Pharmacol (1997) 1.44
Biosynthesis of glycosylphosphatidylinositol (GPI)-anchored membrane proteins in intact cells: specific amino acid requirements adjacent to the site of cleavage and GPI attachment. J Cell Biol (1993) 1.43
The binding of RNA to various celluloses. Biochem Biophys Res Commun (1973) 1.40
Latex agglutination test for detection of Clostridium difficile toxin in stool samples. J Clin Microbiol (1984) 1.39
An active carbonyl formed during glycosylphosphatidylinositol addition to a protein is evidence of catalysis by a transamidase. J Biol Chem (1995) 1.38
Combined liver-kidney transplantation: analysis of patients with preformed lymphocytotoxic antibodies. Transplant Proc (1988) 1.38
Nerve growth factor stimulates phosphorylation of phospholipase C-gamma in PC12 cells. J Biol Chem (1991) 1.38
Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745,337: a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and nonhuman primate stomach. J Pharmacol Exp Ther (1995) 1.37
Increased turnover of arterial collagen in hypertensive rats. Proc Natl Acad Sci U S A (1978) 1.36
The use of dopamine -hydroxylase as a marker for the central noradrenergic nervous system in rat brain. Proc Natl Acad Sci U S A (1972) 1.35
Cloning, expression, and up-regulation of inducible rat prostaglandin e synthase during lipopolysaccharide-induced pyresis and adjuvant-induced arthritis. J Biol Chem (2000) 1.35
K-252a: a specific inhibitor of the action of nerve growth factor on PC 12 cells. J Neurosci (1988) 1.35
Distribution and regulation of cyclooxygenase-2 in carrageenan-induced inflammation. Br J Pharmacol (1999) 1.34
Modulation of retinoid signalling through NGF-induced nuclear export of NGFI-B. Nat Cell Biol (2000) 1.34
Cell cycle-specific action of nerve growth factor in PC12 cells: differentiation without proliferation. EMBO J (1989) 1.34
Tyrosine hydroxylase. Pharmacol Rev (1966) 1.33
Probable precursors of [Leu]enkephalin and [Met]enkephalin in adrenal medulla: peptides of 3-5 kilodaltons. Proc Natl Acad Sci U S A (1980) 1.32
Biosynthesis of phosphatidylinositol glycan-anchored membrane proteins. Design of a simple protein substrate to characterize the enzyme that cleaves the COOH-terminal signal peptide. J Biol Chem (1991) 1.31
Beyond micromachining: the potential of diatoms. Trends Biotechnol (1999) 1.31
Biochemistry of the enkephalins and enkephalin-containing peptides. Arch Biochem Biophys (1983) 1.31
End-product inhibition of tyrosine hydroxylase as a possible mechanism for regulation of norepinephrine synthesis. Mol Pharmacol (1967) 1.31
Homology between a prolyl hydroxylase subunit and a tissue protein that crossreacts immunologically with the enzyme. Proc Natl Acad Sci U S A (1977) 1.30
The discovery of rofecoxib, [MK 966, Vioxx, 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2-inhibitor. Bioorg Med Chem Lett (1999) 1.30
Inhibition of catecholamine synthesis in man with alpha-methyl-tyrosine, an inhibitor of tyrosine hydroxylase. Lancet (1965) 1.29
Replacement lipomatosis of the kidney. AJR Am J Roentgenol (1978) 1.29
Hypothermia and intolerance to cold induced by intracisternal administration of the hypothalamic peptide neurotensin. Nature (1976) 1.29
Binding assay for opioid peptides with neuroblastoma x glioma hybrid cells: specificity of the receptor site. Brain Res (1978) 1.29
Increased phosphorylation of specific nuclear proteins in superior cervical ganglia and PC12 cells in response to nerve growth factor. J Biol Chem (1980) 1.28
Collagen proline hydroxylase in wound healing, granuloma formation, scurvy, and growth. Science (1967) 1.26
Requirements for alpha-ketoglutarate, ferrous ion and ascorbate by collagen proline hydroxylase. Biochem Biophys Res Commun (1966) 1.26
Immunological evidence for an inactive precursor of collagen proline hydroxylase in cultured fibroblasts. Proc Natl Acad Sci U S A (1971) 1.26
Characterization of the phosphatidylinositol-glycan membrane anchor of human placental alkaline phosphatase. Proc Natl Acad Sci U S A (1987) 1.25
Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3. Eur J Biochem (1999) 1.24
Co-release of enkephalin and catecholamines from cultured adrenal chromaffin cells. Nature (1981) 1.23
Processing at the carboxyl terminus of nascent placental alkaline phosphatase in a cell-free system: evidence for specific cleavage of a signal peptide. Proc Natl Acad Sci U S A (1989) 1.23
Prolyl hydroxylase and an immunologically related protein in mammalian tissues. Arch Biochem Biophys (1974) 1.22
Restoration of renal function by arterial surgery. Lancet (1974) 1.21