Published in Thymus on January 01, 1984
Management of chronic hepatitis B infection: current treatment guidelines, challenges, and new developments. World J Gastroenterol (2014) 1.10
Preliminary results of Thymosin-a1 versus interferon-alpha-treatment in patients with HBeAg negative and serum HBV DNA positive chronic hepatitis B. World J Gastroenterol (2001) 0.99
A randomized controlled clinical trial on the treatment of Thymosin a1 versus interferon-alpha in patients with hepatitis B. World J Gastroenterol (2001) 0.90
Efficacy of thymosin alpha-1 and interferon alpha in treatment of chronic viral hepatitis B: a randomized controlled study. World J Gastroenterol (2006) 0.88
Effects of antiviral therapy on preventing liver tumorigenesis and hepatocellular carcinoma recurrence. World J Gastroenterol (2013) 0.85
Investigational agents for treatment of traumatic brain injury. Expert Opin Investig Drugs (2015) 0.84
Advances in immunomodulating therapy of HBV infection. Int J Med Sci (2005) 0.83
Role of Marine Natural Products in the Genesis of Antiviral Agents. Chem Rev (2015) 0.82
Treatment with lamivudine versus lamivudine and thymosin alpha-1 for e antigen-positive chronic hepatitis B patients: a meta-analysis. Virol J (2009) 0.78
The Escherichia coli-derived thymosin β4 concatemer promotes cell proliferation and healing wound in mice. Biomed Res Int (2013) 0.77
Generation of mature Nα-terminal acetylated thymosin α 1 by cleavage of recombinant prothymosin α. ScientificWorldJournal (2013) 0.77
Expression, purification and characterization of a novel soluble human thymosin alpha1 concatemer exhibited a stronger stimulation on mice lymphocytes proliferation and higher anti-tumor activity. Int J Biol Sci (2011) 0.77
Thymosin beta 4: A novel corneal wound healing and anti-inflammatory agent. Clin Ophthalmol (2007) 0.76
Future Therapy for Hepatitis B Virus: Role of Immunomodulators. Curr Hepatol Rep (2016) 0.75
Direct allelic variation scanning of the yeast genome. Science (1998) 5.90
Isolation and characterization of RAT1: an essential gene of Saccharomyces cerevisiae required for the efficient nucleocytoplasmic trafficking of mRNA. Genes Dev (1992) 5.84
Purification and biological activity of thymosin, a hormone of the thymus gland. Proc Natl Acad Sci U S A (1972) 3.24
Preparation, assay, and partial purification of a thymic lymphocytopoietic factor (thymosin). Proc Natl Acad Sci U S A (1966) 3.16
Appearance of T-cell markers in bone marrow rosette-forming cells after incubation with thymosin, a thymic hormone. Proc Natl Acad Sci U S A (1971) 3.13
Differentiation of T cells induced by preparations from thymus and by nonthymic agents. J Exp Med (1973) 3.12
Dbp5p/Rat8p is a yeast nuclear pore-associated DEAD-box protein essential for RNA export. EMBO J (1998) 3.02
Thymosin alpha1: isolation and sequence analysis of an immunologically active thymic polypeptide. Proc Natl Acad Sci U S A (1977) 2.45
Purification and properties of bovine thymosin. Ann N Y Acad Sci (1975) 2.08
The chemistry and biology of thymosin. I. Isolation, characterization, and biological activities of thymosin alpha1 and polypeptide beta1 from calf thymus. J Biol Chem (1979) 2.03
Complete amino acid sequence of bovine thymosin beta 4: a thymic hormone that induces terminal deoxynucleotidyl transferase activity in thymocyte populations. Proc Natl Acad Sci U S A (1981) 1.90
Isogeneic lymphocyte interaction: recognition of self antigens by cells of the neonatal thymus. Proc Natl Acad Sci U S A (1970) 1.78
Neutralization of HTLV-III/LAV replication by antiserum to thymosin alpha 1. Science (1986) 1.75
Ontogenesis of cell-mediated immunity in murine thymocytes and spleen cells and its acceleration by thymosin, a thymic hormone. J Immunol (1971) 1.73
Influenza: response of T-cell lymphopenia to thymosin. N Engl J Med (1976) 1.69
Thymosin activity in patients with cellular immunodeficiency. N Engl J Med (1975) 1.67
Complete covalent structure of a human IgA1 immunoglobulin. Science (1976) 1.67
Influence of thymosin on cell-mediated and humoral immune responses in normal and in immunologically deficient mice. J Immunol (1970) 1.62
Thymosin beta4 accelerates wound healing. J Invest Dermatol (1999) 1.50
Thymosin beta 4 stimulates directional migration of human umbilical vein endothelial cells. FASEB J (1997) 1.46
Influence of thymosin on immunological competence of lymphoid cells from thymectomized mice. Nature (1968) 1.45
Acceleration by thymosin of the development of resistance to murine sarcoma virus-induced tumor in mice. Proc Natl Acad Sci U S A (1970) 1.38
Rapamycin and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependent inhibition of TOR. Antimicrob Agents Chemother (2001) 1.37
Primary structure of a human IgA1 immunoglobulin. IV. Streptococcal IgA1 protease, digestion, Fab and Fc fragments, and the complete amino acid sequence of the alpha 1 heavy chain. J Biol Chem (1979) 1.36
The chemistry and biology of thymosin. II. Amino acid sequence analysis of thymosin alpha1 and polypeptide beta1. J Biol Chem (1979) 1.34
Thymosin restores T cell function and reduces the incidence of amyloid disease in casein-treated mice. J Immunol (1976) 1.31
Thymosin stimulates secretion of luteinizing hormone-releasing factor. Science (1981) 1.31
C-terminal truncations of the yeast nucleoporin Nup145p produce a rapid temperature-conditional mRNA export defect and alterations to nuclear structure. Mol Cell Biol (1997) 1.31
Immunological characterization of homosexual males. Cancer Res (1983) 1.29
Thymosin beta 4 (Fx peptide) is a potent regulator of actin polymerization in living cells. Proc Natl Acad Sci U S A (1992) 1.29
Current status of thymosin and other hormones of the thymus gland. Recent Prog Horm Res (1981) 1.25
Structure, function, and evolutionary relationships of Fc domains of human immunoglobulins A, G, M, and E. Science (1976) 1.22
Immunochemical studies on thymosin: radioimmunoassay of thymosin alpha 1. J Immunol (1982) 1.21
Thymosin corrects the abnormal DNA synthetic response of NZB mouse thymocytes. Proc Natl Acad Sci U S A (1974) 1.19
New role for 15-hydroxyeicosatetraenoic acid. Activator of leukotriene biosynthesis in PT-18 mast/basophil cells. J Biol Chem (1982) 1.18
Influences of aging and dietary restriction on serum thymosin alpha 1 levels in mice. J Gerontol (1988) 1.16
Induction of terminal deoxynucleotidyl transferase and Lyt antigens with thymosin: identification of multiple subsets of prothymocytes in mouse bone marrow and spleen. Proc Natl Acad Sci U S A (1981) 1.13
T-lymphocyte maturation: cell surface markers and immune function induced by T-lymphocyte cell-free products and thymosin polypeptides. Ann N Y Acad Sci (1979) 1.12
Thymosin: effects on normal human blood T-cells. Ann N Y Acad Sci (1975) 1.12
Immunoglobulin synthesis in hereditarily spleenless mice. Nature (1969) 1.12
Cultured human endothelial cells treated with recombinant leukocyte A interferon. Tubuloreticular inclusion formation, antiproliferative effect, and 2',5' oligoadenylate synthetase induction. Lab Invest (1988) 1.11
Effects of the thymus lymphocytopoietic factor. Ann N Y Acad Sci (1966) 1.09
Human immunodeficiency virus contains an epitope immunoreactive with thymosin alpha 1 and the 30-amino acid synthetic p17 group-specific antigen peptide HGP-30. Proc Natl Acad Sci U S A (1987) 1.07
Thymosin beta4 promotes angiogenesis, wound healing, and hair follicle development. Mech Ageing Dev (2004) 1.07
Immunotherapy: new hope for the cancer patient. Am Fam Physician (1973) 1.07
Age-related changes in localization of thymosin in the human thymus. Thymus (1982) 1.07
Reduction in the incidence of wasting disease in neonatally thymectomized CBA-W mice by the injection of thymosin. Endocrinology (1970) 1.06
Thymosin-induced reduction of "null cells" in peripheral-blood lymphocytes of patients with systemic lupus erythematosus. Lancet (1975) 1.05
Regulation of normal and leukaemic lymphocyte transformation and recirculation by sodium periodate oxidation and sodium borohydride reduction. Nat New Biol (1972) 1.05
HGP-30, a synthetic analogue of human immunodeficiency virus (HIV) p17, is a target for cytotoxic lymphocytes in HIV-infected individuals. Proc Natl Acad Sci U S A (1990) 1.05
Chemical characterization of thymosin beta 4. J Biol Chem (1982) 1.04
Elevated serum thymosin alpha 1 levels associated with evidence of immune dysregulation in male homosexuals with a history of infectious diseases or Kaposi's sarcoma. N Engl J Med (1983) 1.03
The thymus as an endocrine gland: properties of thymosin, a new thymus hormone. Recent Prog Horm Res (1970) 1.03
Use of thymosin in the treatment of primary immunodeficiency diseases and cancer. Med Clin North Am (1976) 1.02
Modulation of human natural killer cell cytotoxic activity, lymphokine production, and interleukin 2 receptor expression by thymic hormones. J Immunol (1987) 1.01
Thymosin alpha 1 and thymosin beta 4 in serum: comparison of normal, cord, homosexual and AIDS serum. Int J Immunopharmacol (1986) 1.01
In vitro and in vivo studies with thymosin in cancer patients. Ann N Y Acad Sci (1976) 1.00
Current status of thymosin research: evidence for the existence of a family of thymic factors that control T-cell maturation. Ann N Y Acad Sci (1979) 1.00
Matrigel induces thymosin beta 4 gene in differentiating endothelial cells. J Cell Sci (1995) 1.00
Effect of thymosin and an antithymosin serum on allograft survival in mice. Proc Natl Acad Sci U S A (1968) 0.99
Acceleration of lymphoid tissue regeneration in x-irradiated CBA-W mice by injection of thymosin. Radiat Res (1970) 0.99
Alterations in lymphocyte populations in tumorigenesis. I. Lymphocyte trapping. J Immunol (1973) 0.98
Para-aminobenzoate synthase gene of Saccharomyces cerevisiae encodes a bifunctional enzyme. Yeast (1993) 0.98
Correction of T cell function by thymosin in New Zealand mice. J Immunol (1974) 0.98
Production of biologically active N alpha-desacetylthymosin alpha 1 in Escherichia coli through expression of a chemically synthesized gene. Biochemistry (1980) 0.97
Induction in vivo and in vitro of terminal deoxynucleotidyl transferase by thymosin in bone marrow cells from athymic mice. J Exp Med (1978) 0.97
Thymosin and the immunopathology of aging. Fed Proc (1974) 0.97
Abnormal T-lymphocyte subpopulations associated with transfusion of blood-derived products. Lancet (1983) 0.96
Immunologic and anatomic consequences of calf thymosin injection in rats. Cell Immunol (1970) 0.96
Requirement of thymus-derived theta-positive lymphocytes for rejection of DNA virus (SV 40) tumors in mice. J Immunol (1974) 0.95
Thymic hormones--a clinical update. Springer Semin Immunopathol (1986) 0.95
Hormonal influences on the reticuloendothelial system: current status of the role of thymosin in the regulation and modulation of immunity. J Reticuloendothel Soc (1978) 0.95
Biodistribution of synthetic thymosin beta 4 in the serum, urine, and major organs of mice. Int J Immunopharmacol (1997) 0.94
Ataxia-Telangiectasia: a multiparameter analysis of eight families. Clin Immunol Immunopathol (1982) 0.94
Suppression by thymosin of pokeweed mitogen-induced differentiation of human B cells. Clin Immunol Immunopathol (1978) 0.94
Cellular levels of thymosin immunoreactive peptides are linked to proliferative events: evidence for a nuclear site of action. Proc Natl Acad Sci U S A (1990) 0.94
Isolation of thymosin alpha 1 from thymosin fraction 5 of different species by high-performance liquid chromatography. J Chromatogr (1983) 0.94
The in vitro induction of differentiation of putative human stem cells by thymosin and agents that affect cyclic AMP. Clin Immunol Immunopathol (1978) 0.93
In vivo induction of apoptosis in immature thymocytes by staphylococcal enterotoxin B. J Immunol (1992) 0.92
Increased circulation of T lymphocytes bearing surface thymosin alpha 1 in patients with myasthenia gravis: effect of thymectomy. Neurology (1983) 0.91
Mechanism of action of thymosin. II. Effects of aspirin and thymosin on enhancement of IL-2 production. Immunopharmacology (1985) 0.91
Aspirin and thymosin increase interleukin-2 and interferon-gamma production by human peripheral blood lymphocytes. Immunopharmacology (1989) 0.91
Presence of thymosin-like factors in human thymic epithelium conditioned medium. Int J Immunopharmacol (1979) 0.89
Thymosin alpha 1 antagonizes dexamethasone and CD3-induced apoptosis of CD4+ CD8+ thymocytes through the activation of cAMP and protein kinase C dependent second messenger pathways. Mech Ageing Dev (1997) 0.89
Modulation of interleukin 2 receptor expression on normal human lymphocytes by thymic hormones. Proc Natl Acad Sci U S A (1986) 0.89
Peripheral blood mononuclear cell interleukin-2 and interferon-gamma production, cytotoxicity, and antigen-stimulated blastogenesis during experimental rhinovirus infection. J Infect Dis (1990) 0.89
Reversal by thymosin of increased susceptibility of immunosuppressed mice to Moloney sarcoma virus. Transplant Proc (1971) 0.89
Heterogeneity and age dependency of human thymus reticulo-epithelium in production of thymosin components. Thymus (1985) 0.89