Published in Science on December 07, 1984
High mutation rate of a spleen necrosis virus-based retrovirus vector. Mol Cell Biol (1986) 3.57
Lysine residue 121 in the proposed ATP-binding site of the v-mos protein is required for transformation. Proc Natl Acad Sci U S A (1985) 1.74
The v-sis/PDGF-2 transforming gene product localizes to cell membranes but is not a secretory protein. EMBO J (1985) 1.72
Identification of a signal for nuclear targeting in platelet-derived-growth-factor-related molecules. Mol Cell Biol (1987) 1.38
Activation of oncogenicity of the c-rel proto-oncogene. Mol Cell Biol (1986) 1.31
Transformation by the v-fms oncogene product: role of glycosylational processing and cell surface expression. Mol Cell Biol (1985) 1.22
Nucleotide sequence of transforming human c-sis cDNA clones with homology to platelet-derived growth factor. Nucleic Acids Res (1985) 1.18
Autocrine transformation by chimeric signal peptide-basic fibroblast growth factor: reversal by suramin. Proc Natl Acad Sci U S A (1990) 1.16
Structure and nucleotide sequence of the 5' region of the human and feline c-sis proto-oncogenes. Nucleic Acids Res (1986) 1.16
Deletions in the C-terminal coding region of the v-sis gene: dimerization is required for transformation. Mol Cell Biol (1986) 1.13
Biologically active mutants with deletions in the v-mos oncogene assayed with retroviral vectors. Mol Cell Biol (1985) 1.13
In vitro mutagenesis of the v-sis transforming gene defines functional domains of its growth factor-related product. Proc Natl Acad Sci U S A (1985) 1.07
Autocrine stimulation by the v-sis gene product requires a ligand-receptor interaction at the cell surface. J Cell Biol (1988) 1.07
The B chain of PDGF alone is sufficient for mitogenesis. EMBO J (1985) 1.07
Cell surface expression of membrane-anchored v-sis gene products: glycosylation is not required for cell surface transport. J Cell Biol (1986) 1.05
Identification of nonessential disulfide bonds and altered conformations in the v-sis protein, a homolog of the B chain of platelet-derived growth factor. Mol Cell Biol (1988) 1.02
Deletions in the N-terminal coding region of the v-sis gene: determination of the minimal transforming region. J Virol (1986) 1.00
Biosynthesis of the v-sis gene product: signal sequence cleavage, glycosylation, and proteolytic processing. Mol Cell Biol (1986) 0.98
Secretory protein traffic. Chromogranin A contains a dominant targeting signal for the regulated pathway. J Clin Invest (1993) 0.95
Genetic organization of the c-sis transcription unit. Nucleic Acids Res (1987) 0.87
The v-sis protein retains biological activity as a type II membrane protein when anchored by various signal-anchor domains, including the hydrophobic domain of the bovine papilloma virus E5 oncoprotein. J Cell Biol (1993) 0.86
A small v-sis/platelet-derived growth factor (PDGF) B-protein domain in which subtle conformational changes abrogate PDGF receptor interaction and transforming activity. Mol Cell Biol (1990) 0.84
The v-rel oncogene encodes a kappa B enhancer binding protein that inhibits NF-kappa B function. Cell (1990) 4.87
Nucleotide sequence and formation of the transforming gene of a mouse sarcoma virus. Nature (1981) 4.05
An improved bacteriophage lambda vector: construction of model recombinants coding for kanamycin resistance. Gene (1977) 3.94
Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. Genes Dev (2000) 3.72
Analysis of a 5' leader sequence on murine leukemia virus 21S RNA: heteroduplex mapping with long reverse transcriptase products. Cell (1978) 3.46
cdc25+ encodes a protein phosphatase that dephosphorylates p34cdc2. Mol Biol Cell (1992) 2.56
In vitro and in vivo regulation of antioxidant response element-dependent gene expression by estrogens. Endocrinology (2003) 2.35
FGFR activation in skeletal disorders: too much of a good thing. Trends Genet (1997) 2.30
Constitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain point mutation found in achondroplasia. EMBO J (1996) 2.14
Nuclear localization of cyclin B1 mediates its biological activity and is regulated by phosphorylation. Proc Natl Acad Sci U S A (1997) 1.85
Comparative study of different isolates of murine sarcoma virus. J Virol (1979) 1.80
Lysine residue 121 in the proposed ATP-binding site of the v-mos protein is required for transformation. Proc Natl Acad Sci U S A (1985) 1.74
Xenopus homolog of the mos protooncogene transforms mammalian fibroblasts and induces maturation of Xenopus oocytes. Proc Natl Acad Sci U S A (1989) 1.69
Heteroduplex analysis of the nonhomology region between Moloney MuLV and the dual host range derivative HIX virus. Cell (1978) 1.67
Activating mutations in the extracellular domain of the fibroblast growth factor receptor 2 function by disruption of the disulfide bond in the third immunoglobulin-like domain. Proc Natl Acad Sci U S A (1998) 1.64
Replication of colicin E1 plasmid DNA in vivo requires no plasmid-encoded proteins. J Bacteriol (1978) 1.63
Rotational coupling of the transmembrane and kinase domains of the Neu receptor tyrosine kinase. Mol Biol Cell (2000) 1.62
Transmission of the polyoma virus middle T gene as the oncogene of a murine retrovirus. Nature (1984) 1.59
Distinct missense mutations of the FGFR3 lys650 codon modulate receptor kinase activation and the severity of the skeletal dysplasia phenotype. Am J Hum Genet (2000) 1.58
Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4. Oncogene (2000) 1.57
Patched1 interacts with cyclin B1 to regulate cell cycle progression. EMBO J (2001) 1.52
RTK mutations and human syndromeswhen good receptors turn bad. Trends Genet (2000) 1.49
Progression from meiosis I to meiosis II in Xenopus oocytes requires de novo translation of the mosxe protooncogene. Proc Natl Acad Sci U S A (1991) 1.48
Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II. Mol Cell Biol (1996) 1.46
The alternatively spliced exon of the platelet-derived growth factor A chain encodes a nuclear targeting signal. Mol Cell Biol (1989) 1.45
Speedy: a novel cell cycle regulator of the G2/M transition. EMBO J (1999) 1.42
Identification of a signal for nuclear targeting in platelet-derived-growth-factor-related molecules. Mol Cell Biol (1987) 1.38
Nuclear localization of IkappaB alpha is mediated by the second ankyrin repeat: the IkappaB alpha ankyrin repeats define a novel class of cis-acting nuclear import sequences. Mol Cell Biol (1998) 1.37
Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation. Mol Biol Cell (2001) 1.36
A novel skeletal dysplasia with developmental delay and acanthosis nigricans is caused by a Lys650Met mutation in the fibroblast growth factor receptor 3 gene. Am J Hum Genet (1999) 1.35
Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction. EMBO J (2000) 1.33
An MSV-specific subgenomic mRNA in MSV-transformed G8-124 cells. Cell (1979) 1.28
Constitutive receptor activation by Crouzon syndrome mutations in fibroblast growth factor receptor (FGFR)2 and FGFR2/Neu chimeras. Proc Natl Acad Sci U S A (1996) 1.25
Cellular transformation by a transmembrane peptide: structural requirements for the bovine papillomavirus E5 oncoprotein. Proc Natl Acad Sci U S A (1994) 1.22
Constitutive activation of fibroblast growth factor receptor 3 by mutations responsible for the lethal skeletal dysplasia thanatophoric dysplasia type I. Cell Growth Differ (1998) 1.19
Requirement for phosphorylation of cyclin B1 for Xenopus oocyte maturation. Mol Biol Cell (1995) 1.18
The v-rel oncogene: insights into the mechanism of transcriptional activation, repression, and transformation. J Virol (1992) 1.16
Protein kinases and protooncogenes: biochemical regulators of the eukaryotic cell cycle. Biochemistry (1991) 1.13
Deletions in the C-terminal coding region of the v-sis gene: dimerization is required for transformation. Mol Cell Biol (1986) 1.13
Biologically active mutants with deletions in the v-mos oncogene assayed with retroviral vectors. Mol Cell Biol (1985) 1.13
Nuclear import of IkappaBalpha is accomplished by a ran-independent transport pathway. Mol Cell Biol (2000) 1.12
Effects of the v-mos oncogene on Xenopus development: meiotic induction in oocytes and mitotic arrest in cleaving embryos. J Cell Biol (1990) 1.12
Use of a specific bacteriophage treatment to reduce Salmonella in poultry products. Poult Sci (2005) 1.11
Concerted participation of NF-kappa B and C/EBP heteromer in lipopolysaccharide induction of serum amyloid A gene expression in liver. J Biol Chem (1995) 1.09
The serine/threonine phosphatase PP5 interacts with CDC16 and CDC27, two tetratricopeptide repeat-containing subunits of the anaphase-promoting complex. J Biol Chem (1997) 1.09
Adenovirus E3-10.4K/14.5K protein complex inhibits tumor necrosis factor-induced translocation of cytosolic phospholipase A2 to membranes. J Virol (1997) 1.08
Phosphorylation of conserved serine residues does not regulate the ability of mosxe protein kinase to induce oocyte maturation or function as cytostatic factor. J Cell Biol (1992) 1.07
Structure and function of platelet-derived growth factor (PDGF) and related proteins. Biochim Biophys Acta (1989) 1.07
Loss of IkappaB alpha-mediated control over nuclear import and DNA binding enables oncogenic activation of c-Rel. Mol Cell Biol (1998) 1.07
Autocrine stimulation by the v-sis gene product requires a ligand-receptor interaction at the cell surface. J Cell Biol (1988) 1.07
p37mos-associated serine/threonine protein kinase activity correlates with the cellular transformation function of v-mos. J Virol (1986) 1.06
Cell surface expression of membrane-anchored v-sis gene products: glycosylation is not required for cell surface transport. J Cell Biol (1986) 1.05
Meiotic induction by Xenopus cyclin B is accelerated by coexpression with mosXe. Mol Cell Biol (1991) 1.04
Requirement of mosXe protein kinase for meiotic maturation of Xenopus oocytes induced by a cdc2 mutant lacking regulatory phosphorylation sites. Mol Cell Biol (1992) 1.03
Recombinational junctions of variants of Moloney murine sarcoma virus: generation and divergence of a mammalian transforming gene. J Virol (1983) 1.03
Identification of nonessential disulfide bonds and altered conformations in the v-sis protein, a homolog of the B chain of platelet-derived growth factor. Mol Cell Biol (1988) 1.02
Embryotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): the embryonic vasculature is a physiological target for TCDD-induced DNA damage and apoptotic cell death in Medaka (Orizias latipes). Toxicol Appl Pharmacol (1996) 1.00
Deletions in the N-terminal coding region of the v-sis gene: determination of the minimal transforming region. J Virol (1986) 1.00
Differential pp40I kappa B-beta inhibition of DNA binding by rel proteins. Mol Cell Biol (1993) 1.00
Demonstration of biological activity and nucleotide sequence of an in vitro synthesized clone of the Moloney murine sarcoma virus mos gene. J Virol (1982) 0.99
Enhanced signaling and morphological transformation by a membrane-localized derivative of the fibroblast growth factor receptor 3 kinase domain. Mol Cell Biol (1997) 0.98
Biosynthesis of the v-sis gene product: signal sequence cleavage, glycosylation, and proteolytic processing. Mol Cell Biol (1986) 0.98
Repression of cancer protective genes by 17beta-estradiol: ligand-dependent interaction between human Nrf2 and estrogen receptor alpha. Mol Cell Endocrinol (2005) 0.98
The reverse two-hybrid system: a genetic scheme for selection against specific protein/protein interactions. Nucleic Acids Res (1996) 0.96
Identification of a C/EBP-Rel complex in avian lymphoid cells. Mol Cell Biol (1994) 0.96
The histidine-221 to tyrosine substitution in v-mos abolishes its biological function and its protein kinase activity. Virology (1988) 0.95
Evaluation of Salmonella-vectored Campylobacter peptide epitopes for reduction of Campylobacter jejuni in broiler chickens. Clin Vaccine Immunol (2010) 0.94
Correlation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced apoptotic cell death in the embryonic vasculature with embryotoxicity. Toxicol Appl Pharmacol (1998) 0.93
The N-terminal nuclear export sequence of IkappaBalpha is required for RanGTP-dependent binding to CRM1. J Biol Chem (2001) 0.92
Bacteriocins reduce Campylobacter colonization and alter gut morphology in turkey poults. Poult Sci (2006) 0.90
Intracellular retention of membrane-anchored v-sis protein abrogates autocrine signal transduction. J Cell Biol (1992) 0.89
A generalized method of subcloning DNA fragments by restriction site reconstruction: application to sequencing the amino-terminal coding region of the transforming gene of Gazdar murine sarcoma virus. Nucleic Acids Res (1982) 0.89
Analysis of pesticide residues in eggs by direct sample introduction/gas chromatography/tandem mass spectrometry. J Agric Food Chem (2001) 0.89
Transmembrane domain sequence requirements for activation of the p185c-neu receptor tyrosine kinase. J Cell Biol (1997) 0.88
Tumor necrosis factor-alpha-dependent activation of a RelA homodimer in astrocytes. Increased phosphorylation of RelA and MAD-3 precede activation of RelA. J Biol Chem (1995) 0.87
Expression of transforming region of Moloney murine sarcoma virus in Escherichia coli as a fusion protein with small tumor antigen of polyoma virus. Proc Natl Acad Sci U S A (1982) 0.86
PEST-dependent cytoplasmic retention of v-Rel by I(kappa)B-alpha: evidence that I(kappa)B-alpha regulates cellular localization of c-Rel and v-Rel by distinct mechanisms. J Virol (1996) 0.86
The v-sis protein retains biological activity as a type II membrane protein when anchored by various signal-anchor domains, including the hydrophobic domain of the bovine papilloma virus E5 oncoprotein. J Cell Biol (1993) 0.86
Campylobacter susceptibility to ciprofloxacin and corresponding fluoroquinolone concentrations within the gastrointestinal tracts of chickens. J Appl Microbiol (2005) 0.84
Caprylic acid supplemented in feed reduces enteric Campylobacter jejuni colonization in ten-day-old broiler chickens. Poult Sci (2008) 0.83
Membrane-anchored form of v-sis/PDGF-B induces mitogenesis without detectable PDGF receptor autophosphorylation. J Cell Biol (1991) 0.83
Structure and function of the platelet-derived growth factor family and their receptors. Genet Eng (N Y) (1995) 0.83
Regulation of subcellular localization of the aryl hydrocarbon receptor (AhR). Arch Biochem Biophys (2001) 0.83
Derivatives of activated H-ras lacking C-terminal lipid modifications retain transforming ability if targeted to the correct subcellular location. Oncogene (1997) 0.83
Use of plant-derived antimicrobials for improving the safety of poultry products. Poult Sci (2013) 0.82
Campylobacter biofilm phenotype exhibits reduced colonization potential in young chickens and altered in vitro virulence. Poult Sci (2009) 0.82
Transforming mutant v-mos protein kinases that are deficient in in vitro autophosphorylation. Mol Cell Biol (1989) 0.82
Gastrointestinal maturation is accelerated in turkey poults supplemented with a mannan-oligosaccharide yeast extract (Alphamune). Poult Sci (2007) 0.81
Effects of water- and lipid-soluble antioxidants on turkey sperm viability, membrane integrity, and motility during liquid storage. Poult Sci (1997) 0.81
Upregulation of oxidative burst and degranulation in chicken heterophils stimulated with probiotic bacteria. Poult Sci (2006) 0.81
Plasma concentrations of insulin like growth factors (IGF-)I and IGF-II in dwarf and normal chickens of high and low weight selected lines. Growth Dev Aging (1989) 0.81