Published in Annu Rev Med on January 01, 1984
Violence: an unrecognized environmental exposure that may contribute to greater asthma morbidity in high risk inner-city populations. Environ Health Perspect (2001) 2.38
Circulating catecholamines in acute asthma. Br Med J (Clin Res Ed) (1985) 1.73
Effects of chloro-s-triazine herbicides and metabolites on aromatase activity in various human cell lines and on vitellogenin production in male carp hepatocytes. Environ Health Perspect (2001) 1.53
Airway responsiveness in wheezy infants: evidence for functional beta adrenergic receptors. Thorax (1987) 1.17
Iron deficiency associated with higher blood lead in children living in contaminated environments. Environ Health Perspect (2001) 1.14
The Bordetella bfe system: growth and transcriptional response to siderophores, catechols, and neuroendocrine catecholamines. J Bacteriol (2006) 1.07
Muscarinic receptor antagonists, from folklore to pharmacology; finding drugs that actually work in asthma and COPD. Br J Pharmacol (2011) 1.07
Antibody to VLA-4, but not to L-selectin, protects neuronal M2 muscarinic receptors in antigen-challenged guinea pig airways. J Clin Invest (1997) 1.04
The third nervous system in the lung: physiology and clinical perspectives. Thorax (1984) 1.03
Ipratropium bromide and airways function in wheezy infants. Arch Dis Child (1987) 0.97
Modulation of cholinergic neurotransmission in guinea-pig trachea by neuropeptide Y. Br J Pharmacol (1988) 0.93
Functional characterization of muscarinic receptors in murine airways. Br J Pharmacol (1993) 0.88
The influence of hydrogen peroxide and histamine on lung permeability and translocation of iridium nanoparticles in the isolated perfused rat lung. Part Fibre Toxicol (2005) 0.85
Perception of neighborhood safety and reported childhood lifetime asthma in the United States (U.S.): a study based on a national survey. PLoS One (2009) 0.84
Effect of ciprofloxacin on cholinergic neuro-effector transmission in airway smooth muscle. Drugs (1995) 0.82
Distribution of galanin immunoreactivity in the respiratory tract of pig, guinea pig, rat, and dog. Thorax (1985) 0.82
The role of tiotropium in the management of asthma. Asia Pac Allergy (2012) 0.82
Role of parasympathetic nerves and muscarinic receptors in allergy and asthma. Chem Immunol Allergy (2012) 0.81
Obesity and symptoms of depression contribute independently to the poor asthma control of obesity. Respir Med (2014) 0.80
Hyperinsulinemia potentiates airway responsiveness to parasympathetic nerve stimulation in obese rats. Am J Respir Cell Mol Biol (2014) 0.80
Catecholamines released from the adrenal medulla exert a compensatory, protective effect at beta 2-adrenoceptors against Paf-induced death in mice. Br J Pharmacol (1988) 0.79
Aging and cholinergic responses in bovine trachealis muscle. Br J Pharmacol (1988) 0.79
Interleukin-1β mediates virus-induced m2 muscarinic receptor dysfunction and airway hyperreactivity. Am J Respir Cell Mol Biol (2014) 0.79
Comparative effects of rilmenidine and clonidine on bronchial responses to histamine in asthmatic subjects. Br J Clin Pharmacol (1988) 0.78
Glial Fibrillary Acidic Protein-Expressing Glia in the Mouse Lung. ASN Neuro (2015) 0.75
Circadian molecular clock in lung pathophysiology. Am J Physiol Lung Cell Mol Physiol (2015) 0.75
The pharmacology of airway hyperresponsiveness and inflammation. Lung (1990) 0.75
Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J (2008) 10.08
Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. N Engl J Med (1997) 8.48
Mechanisms of bronchial hyperreactivity in normal subjects after upper respiratory tract infection. Am Rev Respir Dis (1976) 6.26
Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med (1996) 5.53
Low dose inhaled budesonide and formoterol in mild persistent asthma: the OPTIMA randomized trial. Am J Respir Crit Care Med (2001) 5.47
Increased nitric oxide in exhaled air of asthmatic patients. Lancet (1994) 5.39
Outcomes for COPD pharmacological trials: from lung function to biomarkers. Eur Respir J (2008) 5.38
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet (2001) 5.25
Exhaled breath condensate: methodological recommendations and unresolved questions. Eur Respir J (2005) 5.24
Bronchial hyperreactivity. Am Rev Respir Dis (1980) 4.77
Anti-inflammatory actions of glucocorticoids: molecular mechanisms. Clin Sci (Lond) (1998) 4.31
Addition of leukotriene antagonists to therapy in chronic persistent asthma: a randomised double-blind placebo-controlled trial. Lancet (2001) 3.48
Neutrophilic inflammation in severe persistent asthma. Am J Respir Crit Care Med (1999) 3.44
Asthma as an axon reflex. Lancet (1986) 3.26
Single-dose slow-release aminophylline at night prevents nocturnal asthma. Lancet (1982) 3.21
Exhaled markers of pulmonary disease. Am J Respir Crit Care Med (2001) 3.14
Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12. Mol Cell Biol (2000) 3.13
Role of autonomic nervous system and the cough reflex in the increased responsiveness of airways in patients with obstructive airway disease. J Clin Invest (1967) 3.09
New method for perfusing bronchial arteries: histamine bronchoconstriction and apnea. J Appl Physiol (1966) 2.98
Neural control of human airways in health and disease. Am Rev Respir Dis (1986) 2.97
Exhaled and nasal nitric oxide measurements: recommendations. The European Respiratory Society Task Force. Eur Respir J (1997) 2.79
Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD. Am J Respir Crit Care Med (1997) 2.77
Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma. Thorax (1998) 2.71
Exacerbations of chronic obstructive pulmonary disease. Eur Respir J (2007) 2.65
Bradykinin-induced bronchoconstriction in humans. Mode of action. Am Rev Respir Dis (1987) 2.64
Cytokines in asthma. Thorax (1999) 2.64
Epidermal growth factor system regulates mucin production in airways. Proc Natl Acad Sci U S A (1999) 2.57
Effects of inhaled platelet activating factor on pulmonary function and bronchial responsiveness in man. Lancet (1986) 2.41
Changes in sputum eosinophils predict loss of asthma control. Am J Respir Crit Care Med (2000) 2.33
Tolerance to the nonbronchodilator effects of inhaled beta 2-agonists in asthma. N Engl J Med (1992) 2.32
Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients. Am J Respir Crit Care Med (1996) 2.32
Lower threshold and greater bronchomotor responsiveness of asthmatic subjects to sulfur dioxide. Am Rev Respir Dis (1980) 2.31
Acute and chronic effects of cigarette smoking on exhaled nitric oxide. Am J Respir Crit Care Med (1995) 2.28
Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease. Proc Natl Acad Sci U S A (1997) 2.24
Circulating catecholamines in exercise and hyperventilation induced asthma. Thorax (1981) 2.22
Exhaled carbon monoxide in childhood asthma. J Pediatr (1999) 2.19
Activation and localization of transcription factor, nuclear factor-kappaB, in asthma. Am J Respir Crit Care Med (1998) 2.19
Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages. FASEB J (2001) 2.18
Parameters associated with persistent airflow obstruction in chronic severe asthma. Eur Respir J (2004) 2.18
O3-induced change in bronchial reactivity to methacholine and airway inflammation in humans. J Appl Physiol (1985) (1986) 2.16
Characterization of human tracheal epithelial cells transformed by an origin-defective simian virus 40. Proc Natl Acad Sci U S A (1988) 2.15
Interleukin-8: an important chemoattractant in sputum of patients with chronic inflammatory airway diseases. Am J Physiol (1993) 2.14
STAT4 activation in smokers and patients with chronic obstructive pulmonary disease. Eur Respir J (2004) 2.06
Increased expression of nuclear factor-kappaB in bronchial biopsies from smokers and patients with COPD. Eur Respir J (2002) 2.04
Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers. Am J Respir Crit Care Med (2000) 2.03
The effect of airway epithelium on smooth muscle contractility in bovine trachea. Br J Pharmacol (1985) 1.98
Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration. Biochem Biophys Res Commun (2004) 1.98
Exacerbations of asthma: a descriptive study of 425 severe exacerbations. The FACET International Study Group. Am J Respir Crit Care Med (1999) 1.96
Expression of inducible nitric oxide in human lung epithelial cells. Biochem Biophys Res Commun (1994) 1.96
Effect of histamine, serotonin, and acetylcholine on the peripheral airways. J Appl Physiol (1966) 1.95
Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (1999) 1.94
Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients. Am J Respir Crit Care Med (1999) 1.92
Granulocyte activation markers in induced sputum: comparison between chronic obstructive pulmonary disease, asthma, and normal subjects. Am J Respir Crit Care Med (1997) 1.91
A calcium antagonist, nifedipine, modifies exercise-induced asthma. Thorax (1981) 1.90
Autoradiographic visualization of beta-adrenoceptor subtypes in human lung. Am Rev Respir Dis (1985) 1.89
T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients. Clin Exp Immunol (2009) 1.89
Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils. J Immunol (2000) 1.88
IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo. J Immunol (1999) 1.88
Exercise increases sulfur dioxide-induced bronchoconstriction in asthmatic subjects. Am Rev Respir Dis (1981) 1.86
Novel Pseudomonas product stimulates interleukin-8 production in airway epithelial cells in vitro. J Clin Invest (1994) 1.85
Importance of airway inflammation for hyperresponsiveness induced by ozone. Am Rev Respir Dis (1983) 1.85
Tumor necrosis factor-alpha increases airway responsiveness and sputum neutrophilia in normal human subjects. Am J Respir Crit Care Med (1995) 1.84
A comparison of low-dose inhaled budesonide plus theophylline and high-dose inhaled budesonide for moderate asthma. N Engl J Med (1997) 1.84
Bronchial hyperirritability in healthy subjects after exposure to ozone. Am Rev Respir Dis (1978) 1.82
Induction of cyclo-oxygenase-2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone. Br J Pharmacol (1994) 1.82
Effect of ganglionic blockade on bronchial reactivity in atopic subjects. Am Rev Respir Dis (1980) 1.81
Increased nitric oxide in exhaled air of normal human subjects with upper respiratory tract infections. Eur Respir J (1995) 1.80
Brittle asthma. Thorax (1998) 1.77
Importance of inhaler devices in the management of airway disease. Respir Med (2007) 1.76
Evidence for systemic rather than pulmonary effects of interleukin-5 administration in asthma. Thorax (2001) 1.76
Molecular cloning and primary structure of human 15-lipoxygenase. Biochem Biophys Res Commun (1988) 1.76
Airway inflammation after controlled exposure to diesel exhaust particulates. Am J Respir Crit Care Med (2000) 1.75
Circulating catecholamines in acute asthma. Br Med J (Clin Res Ed) (1985) 1.73
Is immunotherapy for asthma worthwhile? N Engl J Med (1996) 1.72
Sympathetic versus parasympathetic nervous regulation of airways in dogs. J Appl Physiol (1971) 1.71
Active transport of Na+ and Cl- across the canine tracheal epithelium in vitro. Am Rev Respir Dis (1975) 1.71
Effect of inhaled corticosteroids on bones and growth. Eur Respir J (1998) 1.68
Supplementary oxygen in healthy subjects and those with COPD increases oxidative stress and airway inflammation. Thorax (2004) 1.68
Reproducibility of exhaled nitric oxide measurements in healthy and asthmatic adults and children. Eur Respir J (2003) 1.68
Elevated levels of exhaled nitric oxide in bronchiectasis. Am J Respir Crit Care Med (1995) 1.67
Pseudo-steroid resistant asthma. Thorax (1999) 1.67
Nitric oxide is the endogenous neurotransmitter of bronchodilator nerves in humans. Eur J Pharmacol (1992) 1.67
Allergen-induced late asthmatic reactions are associated with elevation of exhaled nitric oxide. Am J Respir Crit Care Med (1995) 1.67
Late response to allergen is associated with increased concentrations of tumor necrosis factor-alpha and IL-5 in induced sputum. J Allergy Clin Immunol (1997) 1.65
Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1alpha, granulocyte-macrophage colony-stimulating factor, and interferon-gamma release from alveolar macrophages in asthma. Am J Respir Crit Care Med (1998) 1.65
Increased exhaled nitric oxide in asthma is mainly derived from the lower respiratory tract. Am J Respir Crit Care Med (1996) 1.65
Prostaglandin D2 potentiates airway responsiveness to histamine and methacholine. Am Rev Respir Dis (1986) 1.65
Low-dose theophylline enhances the anti-inflammatory effects of steroids during exacerbations of COPD. Thorax (2009) 1.65
Bronchial hyperresponsiveness in normal subjects during attenuated influenza virus infection. Am Rev Respir Dis (1991) 1.64
Exhaled nitric oxide: a new lung function test. Thorax (1996) 1.64
Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta. Biochem Biophys Res Commun (1997) 1.63
Adenosine as a vasodilator in primary pulmonary hypertension. Circulation (1991) 1.63
Low-dose theophylline reduces eosinophilic inflammation but not exhaled nitric oxide in mild asthma. Am J Respir Crit Care Med (2001) 1.63
Raised levels of exhaled carbon monoxide are associated with an increased expression of heme oxygenase-1 in airway macrophages in asthma: a new marker of oxidative stress. Thorax (1998) 1.63
Airway hyperresponsiveness induced by platelet-activating factor: role of thromboxane generation. J Pharmacol Exp Ther (1986) 1.62
Relative corticosteroid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma. Thorax (2008) 1.62
Bronchoconstrictor response to inhaled capsaicin in humans. J Appl Physiol (1985) (1985) 1.61
Exhaled nitric oxide in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (1998) 1.60