Published in J Clin Invest on November 01, 1967
Bronchial hyperreactivity to prostaglandin F 2 and histamine in patients with asthma. Br Med J (1973) 2.65
Capsaicin responsiveness and cough in asthma and chronic obstructive pulmonary disease. Thorax (2000) 2.41
Regular treatment with salmeterol for chronic asthma: serious adverse events. Cochrane Database Syst Rev (2008) 2.38
Effect of short-term, low-level nitrogen dioxide exposure on bronchial sensitivity of asthmatic patients. J Clin Invest (1976) 2.33
Protective effect of drugs on histamine-induced asthma. Thorax (1977) 2.02
A centennial history of research on asthma pathogenesis. Am J Respir Cell Mol Biol (2005) 1.72
Effects of methacholine induced bronchoconstriction and procaterol induced bronchodilation on cough receptor sensitivity to inhaled capsaicin and tartaric acid. Thorax (1992) 1.63
Respiratory mechanics and dust exposure in byssinosis. J Clin Invest (1970) 1.58
Asthma, sulfur dioxide and the clean air act. West J Med (1982) 1.41
Maximum expiratory flow rates in induced bronchoconstriction in man. J Clin Invest (1969) 1.40
How many blows really make an FEV1, FVC, or PEFR? Thorax (1983) 1.38
Assessing change in airway calibre--measurement of airway resistance. Br J Clin Pharmacol (1979) 1.29
Bronchial secretion from normal human airways after inhalation of prostaglandin F2alpha, acetylcholine, histamine, and citric acid. Thorax (1977) 1.22
Chronic asthma and improvement with relaxation induced by hypnotherapy. J R Soc Med (1988) 1.18
Effect of maximal respiratory manoeuvres on bronchial sensitivity of asthmatic patients as compared to normal people. Br Med J (1975) 1.16
A possible role of airway epithelium in modulating hyperresponsiveness. Br J Pharmacol (1988) 1.15
Effect of terbutaline sulphate in chronic "allergic" cough. Br Med J (Clin Res Ed) (1983) 1.14
Neutral endopeptidase inhibitors potentiate substance P- and capsaicin-induced cough in awake guinea pigs. J Clin Invest (1988) 1.13
Bronchoconstriction in potroom workers. Br J Ind Med (1979) 1.07
Exercise-induced airways constriction. Thorax (1972) 1.05
Assessment of changes in airway calibre I. Tests of forced expiration. Br J Clin Pharmacol (1979) 1.05
Inhibition of artificially induced cough in man by bronchodilators. Br J Clin Pharmacol (1987) 1.00
Ipratropium bromide in patients with nocturnal asthma. Postgrad Med J (1984) 0.98
Regular treatment with formoterol for chronic asthma: serious adverse events. Cochrane Database Syst Rev (2012) 0.98
Effect of atropine on sputum production. Thorax (1975) 0.96
Recombinant human enkephalinase (neutral endopeptidase) prevents cough induced by tachykinins in awake guinea pigs. J Clin Invest (1989) 0.94
Beta-adrenergic function in airways of healthy and asthmatic subjects. Thorax (1975) 0.93
Dual effect of prostaglandin E2 on normal airways smooth muscle in vivo. Thorax (1982) 0.90
Cholinergic blockade in the prevention of exercise-induced asthma. Thorax (1980) 0.88
Anatomy and neurophysiology of cough: CHEST Guideline and Expert Panel report. Chest (2014) 0.88
Citric acid cough threshold and airway responsiveness in asthmatic patients and smokers with chronic airflow obstruction. Thorax (1991) 0.88
Immediate response to cigarette smoke. Thorax (1982) 0.86
Effects of aerosolized histamine and carbachol in the conscious horse. Can J Comp Med (1985) 0.86
Effect of pH on bronchial response to inhaled histamine. Thorax (1982) 0.84
Autonomic modulations in patients with bronchial asthma based on short-term heart rate variability. Lung India (2012) 0.83
Mechanisms of the bronchoconstrictor effects of deep inspiration in asthmatic patients. Thorax (1979) 0.83
Contribution of a cholinergic reflex mechanism to allergen-induced bronchial hyperreactivity in permanently instrumented, unrestrained guinea-pigs. Br J Pharmacol (1995) 0.82
Airway responsiveness to histamine in man: effect of atropine on in vivo and in vitro comparison. Thorax (1985) 0.81
Time course of bronchoconstrictive response in asthmatic subjects to reduced temperature. Thorax (1977) 0.81
Acid-sensing by airway afferent nerves. Pulm Pharmacol Ther (2013) 0.79
Bronchial provocation tests. Br J Clin Pharmacol (1979) 0.79
Airway irritation and cough evoked by acid: from human to ion channel. Curr Opin Pharmacol (2011) 0.79
Interaction between bronchoconstrictor stimuli on human airway smooth muscle. Yale J Biol Med (1976) 0.78
A model of irritant-induced bronchoconstriction in the spontaneously breathing guinea-pig. Br J Pharmacol (1980) 0.78
Lung volumes. Br J Clin Pharmacol (1979) 0.78
Pathogenesis of asthma: a review. J R Soc Med (1983) 0.77
Update: the search for the human cough receptor. Lung (2014) 0.76
Recent advances in the pathophysiology of asthma. West J Med (1974) 0.75
Lack of effect from a single cigarette challenge on bronchial responsiveness in healthy non-smoking subjects. Thorax (1988) 0.75
Absence of refractoriness in asthmatic subjects after exercise with warm, humid inspirate. Thorax (1985) 0.75
A Brief History of Airway Smooth Muscle's Role in Airway Hyperresponsiveness. J Allergy (Cairo) (2012) 0.75
Occupational asthma. West J Med (1982) 0.75
Changes in the bronchial reactivity of dogs caused by exposure to sulphur dioxide. J Physiol (1983) 0.75
The correlation between allergen, acetylcholine and histamine-induced bronchoconstriction. Agents Actions (1984) 0.75
Advances in the understanding of asthma. West J Med (1979) 0.75
A non-pharmacologic approach to the treatment of exercise-induced bronchospasm. Yale J Biol Med (1981) 0.75
Editorial: Bronchodilators, new and old. Br Med J (1976) 0.75
Bronchodilatory effect of warm air inhalation during quiet breathing. West J Med (1984) 0.75
A rapid plethysmographic method for measuring thoracic gas volume: a comparison with a nitrogen washout method for measuring functional residual capacity in normal subjects. J Clin Invest (1956) 15.11
A new method for measuring airway resistance in man using a body plethysmograph: values in normal subjects and in patients with respiratory disease. J Clin Invest (1956) 14.82
THE ACTION OF HISTAMINE ON THE RESPIRATORY TRACT IN NORMAL AND ASTHMATIC SUBJECTS. J Clin Invest (1946) 6.72
The relationship between airway resistance, airway conductance and lung volume in subjects of different age and body size. J Clin Invest (1958) 4.71
The experimental production of cough in human subjects induced by citric acid aerosols; preliminary studies on the evaluation of antitussive agents. Am J Med Sci (1954) 3.93
New method for perfusing bronchial arteries: histamine bronchoconstriction and apnea. J Appl Physiol (1966) 2.98
MECHANISM OF BRONCHOCONSTRICTION DURING INHALATION OF SULFUR DIOXIDE. J Appl Physiol (1965) 2.87
Effect of a previous deep inspiration on airway resistance in man. J Appl Physiol (1961) 2.72
Mechanism of bronchoconstriction during inhalation of dust. J Appl Physiol (1962) 2.50
METHACHOLINE AEROSOL AS TEST FOR BRONCHIAL ASTHMA. Arch Intern Med (1965) 1.95
Reflex effects of upper airway irritation on total lung resistance and blood pressure. J Appl Physiol (1962) 1.93
STRUCTURE-FUNCTION RELATIONSHIPS IN THE AIRWAYS: BRONCHOCONSTRICTION MEDIATED VIA VAGUS NERVES OR BRONCHIAL ARTERIES; PERIPHERAL LUNG CONSTRICTION MEDIATED VIA PULMONARY ARTERIES. Med Thorac (1965) 1.71
Anesthesia for the asthmatic patient. Anesthesiology (1962) 1.15
Clinical and physiological studies on chronic bronchitis. 3. Bronchial reactivity to inhaled acetylcholine. Acta Allergol (1965) 1.06
Bronchoconstriction in man following single deep inspirations. J Appl Physiol (1963) 1.01
Mechanisms of bronchial hyperreactivity in normal subjects after upper respiratory tract infection. Am Rev Respir Dis (1976) 6.26
Bronchial hyperreactivity. Am Rev Respir Dis (1980) 4.77
New method for perfusing bronchial arteries: histamine bronchoconstriction and apnea. J Appl Physiol (1966) 2.98
Epidermal growth factor system regulates mucin production in airways. Proc Natl Acad Sci U S A (1999) 2.57
Lower threshold and greater bronchomotor responsiveness of asthmatic subjects to sulfur dioxide. Am Rev Respir Dis (1980) 2.31
Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease. Proc Natl Acad Sci U S A (1997) 2.24
O3-induced change in bronchial reactivity to methacholine and airway inflammation in humans. J Appl Physiol (1985) (1986) 2.16
Characterization of human tracheal epithelial cells transformed by an origin-defective simian virus 40. Proc Natl Acad Sci U S A (1988) 2.15
Interleukin-8: an important chemoattractant in sputum of patients with chronic inflammatory airway diseases. Am J Physiol (1993) 2.14
Effect of histamine, serotonin, and acetylcholine on the peripheral airways. J Appl Physiol (1966) 1.95
Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils. J Immunol (2000) 1.88
IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo. J Immunol (1999) 1.88
Exercise increases sulfur dioxide-induced bronchoconstriction in asthmatic subjects. Am Rev Respir Dis (1981) 1.86
Novel Pseudomonas product stimulates interleukin-8 production in airway epithelial cells in vitro. J Clin Invest (1994) 1.85
Importance of airway inflammation for hyperresponsiveness induced by ozone. Am Rev Respir Dis (1983) 1.85
Bronchial hyperirritability in healthy subjects after exposure to ozone. Am Rev Respir Dis (1978) 1.82
Effect of ganglionic blockade on bronchial reactivity in atopic subjects. Am Rev Respir Dis (1980) 1.81
Molecular cloning and primary structure of human 15-lipoxygenase. Biochem Biophys Res Commun (1988) 1.76
Sympathetic versus parasympathetic nervous regulation of airways in dogs. J Appl Physiol (1971) 1.71
Active transport of Na+ and Cl- across the canine tracheal epithelium in vitro. Am Rev Respir Dis (1975) 1.71
Bronchial hyperresponsiveness in normal subjects during attenuated influenza virus infection. Am Rev Respir Dis (1991) 1.64
Airway hyperresponsiveness induced by platelet-activating factor: role of thromboxane generation. J Pharmacol Exp Ther (1986) 1.62
Activation of epidermal growth factor receptors is responsible for mucin synthesis induced by cigarette smoke. Am J Physiol Lung Cell Mol Physiol (2001) 1.59
Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea. Proc Natl Acad Sci U S A (1985) 1.59
Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium. Thorax (2004) 1.57
Resistance to breathing during exercise-induced asthma attacks. Am Rev Respir Dis (1970) 1.55
Relationship of epidermal growth factor receptors to goblet cell production in human bronchi. Am J Respir Crit Care Med (2001) 1.54
Mechanisms by which histamine stimulates rapidly adapting receptors in dog lungs. J Appl Physiol Respir Environ Exerc Physiol (1977) 1.53
IL-13 induces mucin production by stimulating epidermal growth factor receptors and by activating neutrophils. Am J Physiol Lung Cell Mol Physiol (2001) 1.52
Capsaicin-induced cough in humans. Am Rev Respir Dis (1992) 1.49
Leukotriene B4 induces airway hyperresponsiveness in dogs. J Appl Physiol (1985) (1985) 1.49
Enkephalinase inhibitor potentiates mammalian tachykinin-induced contraction in ferret trachea. J Pharmacol Exp Ther (1987) 1.48
Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases. Eur Respir J (2008) 1.44
Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells. J Clin Invest (1990) 1.42
Autonomic regulation of the airways. Annu Rev Med (1984) 1.42
Substance P and vasoactive intestinal peptide degradation by mast cell tryptase and chymase. J Pharmacol Exp Ther (1988) 1.40
Influenza infection causes airway hyperresponsiveness by decreasing enkephalinase. J Appl Physiol (1985) (1988) 1.33
Elastic recoil of the lungs in chronic asthmatic patients before and after therapy. J Appl Physiol (1967) 1.32
Physiologic diagnosis of subclinical emphysema. Am Rev Respir Dis (1973) 1.32
Enkephalinase inhibitor potentiates substance P- and electrically induced contraction in ferret trachea. J Appl Physiol (1985) (1987) 1.31
Autonomic control of airway smooth muscle and airway secretions. Am Rev Respir Dis (1977) 1.31
Enkephalinase inhibitors potentiate substance P-induced secretion of 35SO4-macromolecules from ferret trachea. Exp Lung Res (1987) 1.31
Virus induces airway hyperresponsiveness to tachykinins: role of neutral endopeptidase. J Appl Physiol (1985) (1989) 1.30
Localization of beta-adrenoreceptors in mammalian lung by light microscopic autoradiography. Nature (1982) 1.30
Cigarette smoke induces bronchoconstrictor hyperresponsiveness to substance P and inactivates airway neutral endopeptidase in the guinea pig. Possible role of free radicals. J Clin Invest (1989) 1.29
Effect of the oronasal breathing route on sulfur dioxide-induced bronchoconstriction in exercising asthmatic subjects. Am Rev Respir Dis (1982) 1.27
Control of mucus secretion and ion transport in airways. Annu Rev Physiol (1979) 1.27
Micropipette measurement of airway submucosal gland secretion. Autonomic effects. Am Rev Respir Dis (1980) 1.27
Control of neurotransmission by prostaglandins in canine trachealis smooth muscle. J Appl Physiol Respir Environ Exerc Physiol (1984) 1.27
Hypertonic saline increases vascular permeability in the rat trachea by producing neurogenic inflammation. J Clin Invest (1990) 1.27
In vivo and in vitro effect of bradykinin on bronchial motor tone in normal subjects and patients with airways obstruction. Respiration (1973) 1.26
Selective generation of leukotriene B4 by tracheal epithelial cells from dogs. Biochem Biophys Res Commun (1983) 1.26
Early diagnosis of chronic pulmonary vascular obstruction. Value of pulmonary function tests. Am J Med (1968) 1.26
Neutrophil depletion inhibits airway hyperresponsiveness induced by ozone exposure. Am Rev Respir Dis (1984) 1.23
Substance P-immunoreactive sensory axons in the rat respiratory tract: a quantitative study of their distribution and role in neurogenic inflammation. J Comp Neurol (1992) 1.22
Pseudomonas stimulates interleukin-8 mRNA expression selectively in airway epithelium, in gland ducts, and in recruited neutrophils. Am J Respir Cell Mol Biol (1994) 1.21
Pulmonary diffusing capacity measured at multiple intervals during a single exhalation in man. J Appl Physiol Respir Environ Exerc Physiol (1977) 1.21
Neutral endopeptidase and neurogenic inflammation in rats with respiratory infections. J Appl Physiol (1985) (1989) 1.21
Airway neutral endopeptidase-like enzyme modulates tachykinin-induced bronchoconstriction in vivo. J Appl Physiol (1985) (1988) 1.19
Fluid transport across the canine tracheal epithelium. J Appl Physiol Respir Environ Exerc Physiol (1980) 1.19
Effect of ozone on bronchial reactivity in atopic and nonatopic subjects. Am Rev Respir Dis (1979) 1.19
Unusual disease of pulmonary arteries with dyspnea. Structure-function relationships. Am J Med (1966) 1.18
Effect of vagal blockade on regulation of breathing in conscious dogs. J Appl Physiol (1970) 1.18
Airway hyperresponsiveness and changes in cell counts in bronchoalveolar lavage after ozone exposure in dogs. Am Rev Respir Dis (1984) 1.18
Dog mastocytoma tryptase: affinity purification, characterization, and amino-terminal sequence. Arch Biochem Biophys (1987) 1.17
Human eosinophils induce mucin production in airway epithelial cells via epidermal growth factor receptor activation. J Immunol (2001) 1.16
Antigen-induced airway hyperresponsiveness and pulmonary inflammation in allergic dogs. J Appl Physiol (1985) (1985) 1.15
Bradykinin stimulates Cl secretion and prostaglandin E2 release by canine tracheal epithelium. Am J Physiol (1985) 1.15
Piperazine-induced occupational asthma. J Occup Med (1982) 1.15
Inhibition of neutral endopeptidase potentiates neurogenic inflammation in the rat trachea. J Appl Physiol (1985) (1989) 1.14
Tracheal submucosal gland serous cells stimulated in vitro with adrenergic and cholinergic agonists. A morphometric study. Cell Tissue Res (1981) 1.14
Neutral endopeptidase inhibitors potentiate substance P- and capsaicin-induced cough in awake guinea pigs. J Clin Invest (1988) 1.13
Randomised double-blind placebo-controlled study of the effect of inhibition of nitric oxide synthesis in bradykinin-induced asthma. Lancet (1996) 1.13
Molecular cloning of dog mast cell tryptase and a related protease: structural evidence of a unique mode of serine protease activation. Biochemistry (1989) 1.13
The effects of sodium substitution and ouabain on ion transport by dog tracheal epithelium. Am Rev Respir Dis (1979) 1.11
Screening tests of pulmonary function. N Engl J Med (1970) 1.11
In vivo and in vitro studies on alpha-receptors in human airways. Potentiation with bacterial endotoxin. Scand J Respir Dis (1972) 1.11
Pseudomonas aeruginosa induces MUC5AC production via epidermal growth factor receptor. Eur Respir J (2002) 1.11
Neutral endopeptidase and angiotensin converting enzyme inhibitors potentiate kinin-induced contraction of ferret trachea. J Pharmacol Exp Ther (1988) 1.11
Inhibition of antigen-induced airway hyperresponsiveness by a thromboxane synthetase inhibitor (OKY-046) in allergic dogs. Am Rev Respir Dis (1986) 1.09
Proteolytic enzymes and airway diseases. Eur Respir J (1998) 1.08
Proteinase 3, a potent secretagogue in airways, is present in cystic fibrosis sputum. Am J Respir Cell Mol Biol (1999) 1.08
Localization and release of lysozyme from ferret trachea: effects of adrenergic and cholinergic drugs. Cell Tissue Res (1983) 1.08
Micropipette measurement of airway submucosal gland secretion: laryngeal reflex. Am Rev Respir Dis (1980) 1.07
Treatment of recurrent pleural effusion by pleurodesis with quinacrine. Comparison between instillation by repeated thoracenteses and by tube drainage. Scand J Respir Dis (1979) 1.07
Clinical and physiological studies on chronic bronchitis. 3. Bronchial reactivity to inhaled acetylcholine. Acta Allergol (1965) 1.06
Mast cell chymase. A potent secretagogue for airway gland serous cells. J Immunol (1989) 1.06
Exercise-induced airways constriction. Thorax (1972) 1.05
Dog tracheal epithelial cells in culture synthesize sulfated macromolecular glycoconjugates and release them from the cell surface upon exposure to extracellular proteinases. Exp Lung Res (1987) 1.04
Neural regulation of 35SO4-macromolecule secretion from tracheal glands of ferrets. J Appl Physiol Respir Environ Exerc Physiol (1984) 1.04
Mast cell tryptase causes airway smooth muscle hyperresponsiveness in dogs. J Clin Invest (1989) 1.04
Relation of epidermal growth factor receptor expression to goblet cell hyperplasia in nasal polyps. J Allergy Clin Immunol (2000) 1.03
Distribution of chymase-containing mast cells in human bronchi. J Histochem Cytochem (1992) 1.03
Effect of alpha-adrenergic stimulation on mucus secretion and on ion transport in cat trachea in vitro. Am Rev Respir Dis (1980) 1.03
Involvement of neurogenic inflammation in antigen-induced bronchoconstriction in guinea pigs. Am J Physiol (1993) 1.03
Mucus hypersecretion in bronchiectasis. The role of neutrophil proteases. Am Rev Respir Dis (1992) 1.02
Airways obstruction in pulmonary tuberculosis. Scand J Respir Dis (1966) 1.02
Effect of terbutaline on movement of Cl- and Na+ across the trachea of the dog in vitro. Am Rev Respir Dis (1979) 1.02
Mechanism of rapid, shallow breathing after ozone exposure in conscious dogs. J Appl Physiol Respir Environ Exerc Physiol (1979) 1.02
Neutrophil-dependent goblet cell degranulation: role of membrane-bound elastase and adhesion molecules. Am J Physiol (1998) 1.01