Published in Lancet on October 16, 1976
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The effective period of preventive antibiotic action in experimental incisions and dermal lesions. Surgery (1961) 5.89
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Design of an artificial skin. I. Basic design principles. J Biomed Mater Res (1980) 2.15
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Left ventricular mural thrombi complicating acute myocardial infarction. Long-term follow-up with serial echocardiography. Ann Intern Med (1984) 1.78
Glucose metabolism in man: responses to intravenous glucose infusion. Metabolism (1979) 1.76
Suppression of a nonsense mutation in mammalian cells in vivo by the aminoglycoside antibiotics G-418 and paromomycin. Nucleic Acids Res (1985) 1.71
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Expression of a synthetic gene for horseradish peroxidase C in Escherichia coli and folding and activation of the recombinant enzyme with Ca2+ and heme. J Biol Chem (1990) 1.68
C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro. Comparison with secretion of interleukin 1 beta and interleukin 1 alpha. J Exp Med (1988) 1.67
THE EFFECT OF ANTIBACTERIAL DRUGS ON THE FECAL FLORA OF MICE. J Exp Med (1963) 1.65
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Membrane permeability changes associated with DNA gyrase inhibitors in Escherichia coli. Antimicrob Agents Chemother (1985) 1.61
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Glucose metabolism in severely burned patients. Metabolism (1979) 1.57
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Increased gut permeability early after burns correlates with the extent of burn injury. Crit Care Med (1992) 1.53
Primary burn excision and immediate grafting: a method shortening illness. J Trauma (1974) 1.52
The expanding spectrum of Behçet syndrome: a case with renal involvement. JAMA (1977) 1.51
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A new biologic role for C3a and C3a desArg: regulation of TNF-alpha and IL-1 beta synthesis. J Immunol (1996) 1.47
Expression of Drosophila heat shock genes is regulated in Rat-cells. Nucleic Acids Res (1982) 1.46
Glucose requirements following burn injury. Parameters of optimal glucose infusion and possible hepatic and respiratory abnormalities following excessive glucose intake. Ann Surg (1979) 1.45
Significant reductions in mortality for children with burn injuries through the use of prompt eschar excision. Ann Surg (1988) 1.45
Enzymes depending on the pterin molybdenum cofactor: sequence families, spectroscopic properties of molybdenum and possible cofactor-binding domains. Biochim Biophys Acta (1991) 1.45
Maximal parenteral glucose oxidation in hypermetabolic young children: a stable isotope study. JPEN J Parenter Enteral Nutr (1998) 1.45
Primary excision and prompt grafting as routine therapy for the treatment of thermal burns in children. Surg Clin North Am (1976) 1.44
Differential roles of Toll-like receptors in the elicitation of proinflammatory responses by macrophages. Ann Rheum Dis (2001) 1.42
C5a induction of human interleukin 1. Synergistic effect with endotoxin or interferon-gamma. J Immunol (1987) 1.41
Whole-body leucine and lysine metabolism: response to dietary protein intake in young men. Am J Physiol (1981) 1.41
Tracer priming the bicarbonate pool. J Appl Physiol Respir Environ Exerc Physiol (1978) 1.40
Wound tissue can utilize a polymeric template to synthesize a functional extension of skin. Science (1982) 1.39
Lasting biological effects of early environmental influences. I. Conditioning of adult size by prenatal and postnatal nutrition. J Exp Med (1968) 1.39
A comparison of the effects of cyclosporine versus antilymphocyte globulin on delayed graft function in cadaver renal transplant recipients. Transplantation (1989) 1.39
Epidemiology of infections with Pseudomonas aeruginosa in burn patients: the role of hydrotherapy. Clin Infect Dis (1992) 1.36
Design of an artificial skin. Part III. Control of pore structure. J Biomed Mater Res (1980) 1.36
Efficient immortalization and morphological transformation of human fibroblasts by transfection with SV40 DNA linked to a dominant marker. Exp Cell Res (1986) 1.35
Antibiotics in surgery. Arch Surg (1975) 1.34
Acute diffuse interstitial nephritis. Review of the literature and case report. Am J Med (1968) 1.32
Prompt eschar excision: a treatment system contributing to reduced burn mortality. A statistical evaluation of burn care at the Massachusetts General Hospital (1974-1984). Ann Surg (1986) 1.32
Peritoneal reactions to particulate matter in peritoneal dialysis solutions. Trans Am Soc Artif Intern Organs (1975) 1.32
The acutely burned hand: management and outcome based on a ten-year experience with 1047 acute hand burns. J Trauma (1995) 1.32
The origin of urinary dimethylamine. Biochim Biophys Acta (1965) 1.32
Immunosuppression and temporary skin transplantation in the treatment of massive third degree burns. Ann Surg (1975) 1.26
The indigenous flora of the gastrointestinal tract. Dis Colon Rectum (1967) 1.26
Response of protein and urea kinetics in burn patients to different levels of protein intake. Ann Surg (1983) 1.25
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Interleukin-1 beta in human plasma: optimization of blood collection, plasma extraction, and radioimmunoassay methods. Lymphokine Res (1988) 1.22
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A human gene encoding morphine modulating peptides related to NPFF and FMRFamide. FEBS Lett (1997) 1.22
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An assay for transient gene expression in transfected Drosophila cells, using [3H]guanine incorporation. EMBO J (1984) 1.21
Quantitative study in vivo of methionine cycle in humans using [methyl-2H3]- and [1-13C]methionine. Am J Physiol (1988) 1.21
Biochemical profile or uremic breath. N Engl J Med (1977) 1.20
National transplantation Pregnancy Registry--outcomes of 154 pregnancies in cyclosporine-treated female kidney transplant recipients. Transplantation (1994) 1.19
Temporary skin transplantation and immunosuppression for extensive burns. N Engl J Med (1974) 1.19
Measurement of plasma free fatty acid turnover and oxidation using [1-13C]palmitic acid. Biomed Mass Spectrom (1980) 1.17
Tracheostomy complicating massive burn injury. A plea for conservatism. Am J Surg (1974) 1.17
Patterns of high tension electrical injury in children and adolescents and their management. Am J Surg (1977) 1.16
Pulmonary resection for metastatic neoplasms in the lung. Experience at the Massachusetts General Hospital. Am J Surg (1978) 1.15
Recovery of 13C in breath from NaH13CO3 infused by gut and vein: effect of feeding. Am J Physiol (1989) 1.15
Platelet dysfunction in uremia. Multifaceted defect partially corrected by dialysis. Am J Med (1985) 1.15
The constancy of the alpha-1-acid glycoprotein variants of normal adults under conditions of severe stress. J Clin Invest (1966) 1.14
The Microbial ecology of the upper small bowel. Am J Gastroenterol (1976) 1.14
The realiability of rates of glucose appearance in vivo calculated from constant tracer infusions. Biochem J (1978) 1.12
Ultrastructural studies on the lymphatic anchoring filaments. J Cell Biol (1968) 1.12
Association of enzymes with replicating and nonreplicating simian virus 40 chromosomes. Cold Spring Harb Symp Quant Biol (1979) 1.11
Effect of insurance status on postacute care among working age stroke survivors. Neurology (2012) 1.11
Thermal injury induces very early production of interleukin-1 alpha in the rat by mechanisms other than endotoxemia. Surgery (1994) 1.09
Dietary arginine uptake by the splanchnic region in adult humans. Am J Physiol (1993) 1.09
Increased rates of whole body protein synthesis and breakdown in children recovering from burns. Ann Surg (1978) 1.08
Determination of body burden of uremic toxins. Clin Nephrol (1984) 1.07
The role of echocardiography in managing cardiac emboli. West J Med (1989) 1.06
Determination of the isotope enrichment of one or a mixture of two stable labelled tracers of the same compound using the complete isotopomer distribution of an ion fragment; theory and application to in vivo human tracer studies. Biol Mass Spectrom (1993) 1.06
Regulation of the pharynx of Caenorhabditis elegans by 5-HT, octopamine, and FMRFamide-like neuropeptides. J Neurobiol (2001) 1.06
The plasma flux and oxidation rate of ornithine adaptively decline with restricted arginine intake. Proc Natl Acad Sci U S A (1994) 1.06
Disseminated aspergillosis in a presumably immunocompetent host. JAMA (1982) 1.05
Inactivation of a transfected gene in human fibroblasts can occur by deletion, amplification, phenotypic switching, or methylation. Mol Cell Biol (1987) 1.04
A method of secondary closure of heavily contaminated wounds proividing "physiologic primary closure". J Trauma (1968) 1.04