Published in J Immunol on May 01, 1983
Early high-affinity neutralizing anti-viral IgG responses without further overall improvements of affinity. Proc Natl Acad Sci U S A (1995) 1.79
Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli. Proc Natl Acad Sci U S A (1984) 1.36
Carcinoembryonic antigen is anchored to membranes by covalent attachment to a glycosylphosphatidylinositol moiety: identification of the ethanolamine linkage site. Proc Natl Acad Sci U S A (1988) 1.31
CEACAM1 enhances invasion and migration of melanocytic and melanoma cells. Am J Pathol (2004) 1.08
CEACAM1 modulates epidermal growth factor receptor--mediated cell proliferation. J Clin Invest (2004) 1.02
cis Interaction of the cell adhesion molecule CEACAM1 with integrin beta(3). Am J Pathol (2001) 0.95
Regulation of CEACAM1 transcription in human breast epithelial cells. BMC Mol Biol (2010) 0.92
Mutational analysis of the cytoplasmic domain of CEACAM1-4L in humanized mammary glands reveals key residues involved in lumen formation: stimulation by Thr-457 and inhibition by Ser-461. Exp Cell Res (2008) 0.88
Application of PBPK modeling to predict monoclonal antibody disposition in plasma and tissues in mouse models of human colorectal cancer. J Pharmacokinet Pharmacodyn (2012) 0.81
A transition metal complex (Venus flytrap cluster) for radioimmunodetection and radioimmunotherapy. Proc Natl Acad Sci U S A (1991) 0.78
Altered biodistribution of an antibody--enzyme conjugate modified with polyethylene glycol. Br J Cancer (1996) 0.75
Formation of anhydrosugars in the chemical depolymerization of heparin. Biochemistry (1976) 6.00
Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase. Proc Natl Acad Sci U S A (1983) 5.50
In vitro differentiation of endothelial cells from AC133-positive progenitor cells. Blood (2000) 3.57
Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression. Nat Med (1997) 2.88
Development and testing of nursing home quality indicators. Health Care Financ Rev (1995) 2.68
Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1. Genes Dev (2000) 2.58
Redefined nomenclature for members of the carcinoembryonic antigen family. Exp Cell Res (1999) 2.25
Biochemical characterization of a second family of human Ia molecules, HLA-DS, equivalent to murine I-A subregion molecules. J Exp Med (1982) 2.15
E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription. Oncogene (1998) 2.12
Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice. J Clin Invest (1996) 2.00
Urotensin II: a somatostatin-like peptide in the caudal neurosecretory system of fishes. Proc Natl Acad Sci U S A (1980) 2.00
Microsequence analysis of peptides and proteins. II. Separation of amino acid phenylthiohydantoin derivatives by high-performance liquid chromatography on octadecylsilane supports. Anal Biochem (1982) 1.95
Nearest neighbor analysis of heparin: identification and quantitation of the products formed by selective depolymerization procedures. Biochemistry (1976) 1.90
Sequence analysis of carcinoembryonic antigen: identification of glycosylation sites and homology with the immunoglobulin supergene family. Proc Natl Acad Sci U S A (1987) 1.86
Isolation and sequence of an active-site peptide containing a catalytic aspartic acid from two Streptococcus sobrinus alpha-glucosyltransferases. J Biol Chem (1991) 1.81
Numerical selection of optimal tumor imaging agents with application to engineered antibodies. Cancer Biother Radiopharm (2001) 1.81
CEA-related antigens: molecular biology and clinical significance. Crit Rev Oncol Hematol (1985) 1.79
Elastic scattering spectroscopy accurately detects high grade dysplasia and cancer in Barrett's oesophagus. Gut (2006) 1.78
Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction. J Clin Oncol (1994) 1.78
E2F family members are differentially regulated by reversible acetylation. J Biol Chem (2000) 1.77
Hormone-sensitive lipase: sequence, expression, and chromosomal localization to 19 cent-q13.3. Science (1988) 1.69
High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment. Proc Natl Acad Sci U S A (2000) 1.69
Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts. Cancer Res (1996) 1.67
Cloning of Drosophila choline acetyltransferase cDNA. Proc Natl Acad Sci U S A (1986) 1.65
Biliary glycoprotein, a potential human cell adhesion molecule, is down-regulated in colorectal carcinomas. Proc Natl Acad Sci U S A (1993) 1.64
CEA-related cell adhesion molecule 1: a potent angiogenic factor and a major effector of vascular endothelial growth factor. Mol Cell (2000) 1.63
Cytochrome P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues. Proc Natl Acad Sci U S A (1987) 1.63
CD66a (BGP), an adhesion molecule of the carcinoembryonic antigen family, is expressed in epithelium, endothelium, and myeloid cells in a wide range of normal human tissues. J Histochem Cytochem (1996) 1.59
Human apolipoprotein B: partial amino acid sequence. FEBS Lett (1984) 1.54
Prognostic relevance of carcinoembryonic antigen and estrogen receptor status in breast cancer patients. Cancer (1994) 1.50
An improved method for conjugating monoclonal antibodies with N-hydroxysulfosuccinimidyl DOTA. Bioconjug Chem (2001) 1.48
Microsequence analysis of peptides and proteins. V. Design and performance of a novel gas-liquid-solid phase instrument. Anal Biochem (1985) 1.48
The effect of replacement of methionine by homocystine on survival of malignant and normal adult mammalian cells in culture. Proc Natl Acad Sci U S A (1974) 1.48
Methods for detection of point mutations: performance and quality assessment. IFCC Scientific Division, Committee on Molecular Biology Techniques. Clin Chem (1997) 1.46
Tumor targeting of radiometal labeled anti-CEA recombinant T84.66 diabody and t84.66 minibody: comparison to radioiodinated fragments. Bioconjug Chem (2001) 1.44
Identification and localization of amino acid substitutions between two phenobarbital-inducible rat hepatic microsomal cytochromes P-450 by micro sequence analyses. Proc Natl Acad Sci U S A (1983) 1.43
Specificity of reverse transcriptase polymerase chain reaction assays designed for the detection of circulating cancer cells is influenced by cytokines in vivo and in vitro. Br J Cancer (1998) 1.42
Immunocytological detection of micrometastatic cells: comparative evaluation of findings in the peritoneal cavity and the bone marrow of gastric, colorectal and pancreatic cancer patients. Int J Cancer (1994) 1.39
Identification of des-(Gly-Ile)-endozepine as an effector of corticotropin-dependent adrenal steroidogenesis: stimulation of cholesterol delivery is mediated by the peripheral benzodiazepine receptor. Proc Natl Acad Sci U S A (1989) 1.38
Essential role of biliary glycoprotein (CD66a) in morphogenesis of the human mammary epithelial cell line MCF10F. J Cell Sci (1999) 1.38
Microsequence analysis of peptides and proteins. I. Preparation of samples by reverse-phase liquid chromatography. Anal Biochem (1982) 1.37
Characterization of a cDNA clone for the nonspecific cross-reacting antigen (NCA) and a comparison of NCA and carcinoembryonic antigen. J Biol Chem (1988) 1.36
Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli. Proc Natl Acad Sci U S A (1984) 1.36
Isolation of a tryptic fragment containing the collagen-binding site of plasma fibronectin. J Biol Chem (1979) 1.35
Two adrenal opioid polypeptides: proposed intermediates in the processing of proenkephalin. Proc Natl Acad Sci U S A (1981) 1.34
Tumor localization of anti-CEA single-chain Fvs: improved targeting by non-covalent dimers. Immunotechnology (1996) 1.34
Molecular cloning of a cDNA coding biliary glycoprotein I: primary structure of a glycoprotein immunologically crossreactive with carcinoembryonic antigen. Proc Natl Acad Sci U S A (1988) 1.32
Carcinoembryonic antigen is anchored to membranes by covalent attachment to a glycosylphosphatidylinositol moiety: identification of the ethanolamine linkage site. Proc Natl Acad Sci U S A (1988) 1.31
Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis. Int J Cancer (1995) 1.31
Cloning and physical mapping of a gene fragment coding for a 64-kilodalton major late antigen of human cytomegalovirus. Proc Natl Acad Sci U S A (1984) 1.30
Size and subdomain architecture of the glucan-binding domain of sucrose:3-alpha-D-glucosyltransferase from Streptococcus sobrinus. Infect Immun (1990) 1.29
Binding of Escherichia coli and Salmonella strains to members of the carcinoembryonic antigen family: differential binding inhibition by aromatic alpha-glycosides of mannose. Infect Immun (1991) 1.28
Association of pp60c-src with biliary glycoprotein (CD66a), an adhesion molecule of the carcinoembryonic antigen family downregulated in colorectal carcinomas. Oncogene (1995) 1.28
Amino-terminal amino acid sequence of murine colony-stimulating factor 1. Proc Natl Acad Sci U S A (1985) 1.27
Cloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expression. Mol Cell Biol (1990) 1.26
Carboxy-terminal sequencing: formation and hydrolysis of C-terminal peptidylthiohydantoins. Biochemistry (1990) 1.24
cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family. J Biol Chem (1993) 1.24
Detection of micrometastasis by cytokeratin 20 RT-PCR is limited due to stable background transcription in granulocytes. Br J Cancer (1999) 1.24
Amino acid sequences of three bombesin-like peptides from canine intestine extracts. J Biol Chem (1983) 1.23
Steroid 21-hydroxylase (cytochrome P-450) from porcine adrenocortical microsomes: microsequence analysis of cysteine-containing peptides. Biochemistry (1983) 1.23
Mammalian expression and hollow fiber bioreactor production of recombinant anti-CEA diabody and minibody for clinical applications. J Immunol Methods (2001) 1.22
Enzymatic and chemical digestion of proteins for mass spectrometry. Methods Enzymol (1990) 1.22
The amino acid sequence of a fluorescein-labeled peptide from the active site of (Na,K)-ATPase. J Biol Chem (1984) 1.21
Sequence determinations of proteins and peptides at the nanomole and subnanomole level with a modified spinning cup sequenator. Methods Enzymol (1981) 1.20
Cloning and tissue-specific expression of mouse macrophage colony-stimulating factor mRNA. Proc Natl Acad Sci U S A (1987) 1.18
A highly potent 3200-dalton adrenal opioid peptide that contains both a [Met]- and [Leu]enkephalin sequence. Proc Natl Acad Sci U S A (1981) 1.18
Cloning and characterization of cDNA encoding 3-methylcholanthrene inducible rat mRNA for UDP-glucuronosyltransferase. J Biol Chem (1986) 1.17
Human aromatase: cDNA cloning, Southern blot analysis, and assignment of the gene to chromosome 15. DNA (1988) 1.16
Expression of CD66a (human C-CAM) and other members of the carcinoembryonic antigen gene family of adhesion molecules in human colorectal adenomas. Cancer Res (1997) 1.15
Uronic acid composition of heparins and heparan sulfates. Biochemistry (1973) 1.14
Insulin-like growth factor (IGF) binding protein complementary deoxyribonucleic acid from human HEP G2 hepatoma cells: predicted protein sequence suggests an IGF binding domain different from those of the IGF-I and IGF-II receptors. Mol Endocrinol (1988) 1.14
Carcinoembryonic antigen cell adhesion molecule 1 directly associates with cytoskeleton proteins actin and tropomyosin. J Biol Chem (2001) 1.13
Two-column system for determination of glucosamine, galactosamine, and amino acids on a Beckman 121MB amino acid analyzer: separation of the anomers of glucosamine and galactosamine. Anal Biochem (1979) 1.13
Role of CEACAM1 isoforms in an in vivo model of mammary morphogenesis: mutational analysis of the cytoplasmic domain of CEACAM1-4S reveals key residues involved in lumen formation. Oncogene (2007) 1.13
Stoichiometry of the nitrous acid deaminative cleavage of model amino sugar glycosides and glycosaminoglycuronans. Biochemistry (1970) 1.12
Molecular cloning of a gene belonging to the carcinoembryonic antigen gene family and discussion of a domain model. Proc Natl Acad Sci U S A (1987) 1.12
Differential expression of CD66a (BGP), a cell adhesion molecule of the carcinoembryonic antigen family, in benign, premalignant, and malignant lesions of the human mammary gland. J Histochem Cytochem (1997) 1.11
Detection of intratumoral aromatase in breast carcinomas. An immunohistochemical study with clinicopathologic correlation. Am J Pathol (1992) 1.11
Amino-terminal and carboxy-terminal sequence of hepatic microsomal cytochrome P-450d, a unique hemoprotein from rats treated with isosafrole. Biochemistry (1982) 1.09
Amyloid angiopathy of Alzheimer's disease: amino acid composition and partial sequence of a 4,200-dalton peptide isolated from cortical microvessels. J Neurochem (1987) 1.09
Diagnosis of micrometastases by the amplification of tissue-specific genes. Gene (1995) 1.09
Microsomal cytochrome P-450 from neonatal pig testis: two enzymatic activities (17 alpha-hydroxylase and c17,20-lyase) associated with one protein. Biochemistry (1981) 1.09
A facile, water-soluble method for modification of proteins with DOTA. Use of elevated temperature and optimized pH to achieve high specific activity and high chelate stability in radiolabeled immunoconjugates. Bioconjug Chem (1995) 1.08
Partial structure of a large canine cholecystokinin (CCK58): amino acid sequence. Peptides (1982) 1.08
Energy transfer between two peptides bound to one MHC class II molecule. Science (1991) 1.08
NH2-terminal sequences of DNA-, heparin-, and gelatin-binding tryptic fragments from human plasma fibronectin. Arch Biochem Biophys (1982) 1.08
Expression of biliary glycoprotein (CD66a) in normal and malignant breast epithelial cells. Anticancer Res (1998) 1.07
Isolation and partial chemical characterization of a 64,000-dalton glycoprotein of human cytomegalovirus. J Virol (1984) 1.07
Antigenic sites in carcinoembryonic antigen. Cancer Res (1989) 1.06
Identification of the specific oligosaccharide sites recognized by type 1 fimbriae from Escherichia coli on nonspecific cross-reacting antigen, a CD66 cluster granulocyte glycoprotein. J Biol Chem (1993) 1.06