Published in Anal Biochem on February 15, 1983
The leader mRNA of the histidine attenuator region resembles tRNAHis: possible general regulatory implications. Proc Natl Acad Sci U S A (1983) 3.43
A double-stranded RNA unwinding activity introduces structural alterations by means of adenosine to inosine conversions in mammalian cells and Xenopus eggs. Proc Natl Acad Sci U S A (1989) 3.23
Isolation and characterization of a novel ribonucleoprotein particle: large structures contain a single species of small RNA. J Cell Biol (1986) 1.98
New function of vitamin B12: cobamide-dependent reduction of epoxyqueuosine to queuosine in tRNAs of Escherichia coli and Salmonella typhimurium. J Bacteriol (1988) 1.73
A novel type of RNA editing occurs in the mitochondrial tRNAs of the centipede Lithobius forficatus. Proc Natl Acad Sci U S A (2000) 1.65
RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA. J Am Chem Soc (2010) 1.60
Posttranscriptional modifications in 16S and 23S rRNAs of the archaeal hyperthermophile Sulfolobus solfataricus. J Bacteriol (1998) 1.59
Posttranscriptional modification of tRNA in thermophilic archaea (Archaebacteria). J Bacteriol (1991) 1.57
Post-transcriptional modification in archaeal tRNAs: identities and phylogenetic relations of nucleotides from mesophilic and hyperthermophilic Methanococcales. Nucleic Acids Res (2001) 1.52
Identification of a gene involved in the generation of 4-thiouridine in tRNA. Nucleic Acids Res (1998) 1.51
Identification of the miaB gene, involved in methylthiolation of isopentenylated A37 derivatives in the tRNA of Salmonella typhimurium and Escherichia coli. J Bacteriol (1999) 1.48
Dual function of the tRNA(m(5)U54)methyltransferase in tRNA maturation. RNA (2002) 1.45
A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase. Nucleic Acids Res (2004) 1.44
Isolation and characterization of a selenium metabolism mutant of Salmonella typhimurium. J Bacteriol (1988) 1.38
Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures. Nucleic Acids Res (2003) 1.35
The spoU gene of Escherichia coli, the fourth gene of the spoT operon, is essential for tRNA (Gm18) 2'-O-methyltransferase activity. Nucleic Acids Res (1997) 1.34
Requirement for IscS in biosynthesis of all thionucleosides in Escherichia coli. J Bacteriol (2002) 1.26
Posttranscriptional modification of tRNA in psychrophilic bacteria. J Bacteriol (1997) 1.25
Fluorescent pyrimidine ribonucleotide: synthesis, enzymatic incorporation, and utilization. J Am Chem Soc (2007) 1.23
Formation of the conserved pseudouridine at position 55 in archaeal tRNA. Nucleic Acids Res (2006) 1.15
Identification of the TRM2 gene encoding the tRNA(m5U54)methyltransferase of Saccharomyces cerevisiae. RNA (2000) 1.15
Isolation of the gene (miaE) encoding the hydroxylase involved in the synthesis of 2-methylthio-cis-ribozeatin in tRNA of Salmonella typhimurium and characterization of mutants. J Bacteriol (1993) 1.14
Structural alterations of the tRNA(m1G37)methyltransferase from Salmonella typhimurium affect tRNA substrate specificity. RNA (1999) 1.14
A novel ribosome-associated protein is important for efficient translation in Escherichia coli. J Bacteriol (1997) 1.11
Not all pseudouridine synthases are potently inhibited by RNA containing 5-fluorouridine. RNA (2004) 1.10
Thermospray liquid chromatography-mass spectrometry of nucleosides and of enzymatic hydrolysates of nucleic acids. Nucleic Acids Res (1985) 1.09
Influence of temperature on tRNA modification in archaea: Methanococcoides burtonii (optimum growth temperature [Topt], 23 degrees C) and Stetteria hydrogenophila (Topt, 95 degrees C). J Bacteriol (2003) 1.08
The methylthio group (ms2) of N6-(4-hydroxyisopentenyl)-2-methylthioadenosine (ms2io6A) present next to the anticodon contributes to the decoding efficiency of the tRNA. J Bacteriol (1995) 1.06
Occurrence of selenium-containing tRNAs in mouse leukemia cells. Proc Natl Acad Sci U S A (1984) 1.02
Structure determination of a new fluorescent tricyclic nucleoside from archaebacterial tRNA. Nucleic Acids Res (1987) 1.01
Mechanistic investigations of the pseudouridine synthase RluA using RNA containing 5-fluorouridine. Biochemistry (2006) 1.01
The methyl group of the N6-methyl-N6-threonylcarbamoyladenosine in tRNA of Escherichia coli modestly improves the efficiency of the tRNA. J Bacteriol (1998) 1.00
Structure determination of two new amino acid-containing derivatives of adenosine from tRNA of thermophilic bacteria and archaea. Nucleic Acids Res (1992) 0.98
The human tRNA(m(2)(2)G(26))dimethyltransferase: functional expression and characterization of a cloned hTRM1 gene. Nucleic Acids Res (2000) 0.94
Reduced leu operon expression in a miaA mutant of Salmonella typhimurium. J Bacteriol (1988) 0.92
Quantitative measurement of dihydrouridine in RNA using isotope dilution liquid chromatography-mass spectrometry (LC/MS). Nucleic Acids Res (1996) 0.90
Assay of both activities of the bifunctional tRNA-modifying enzyme MnmC reveals a kinetic basis for selective full modification of cmnm5s2U to mnm5s2U. Nucleic Acids Res (2011) 0.84
Novel salvage of queuine from queuosine and absence of queuine synthesis in Chlorella pyrenoidosa and Chlamydomonas reinhardtii. J Bacteriol (1988) 0.83
Characterisation of a prokaryote-type tRNA-isopentenyltransferase gene from the moss Physcomitrella patens. Planta (2007) 0.83
The identification and characterization of non-coding and coding RNAs and their modified nucleosides by mass spectrometry. RNA Biol (2014) 0.83
The ms2io6A37 modification of tRNA in Salmonella typhimurium regulates growth on citric acid cycle intermediates. J Bacteriol (1998) 0.81
TtcA a new tRNA-thioltransferase with an Fe-S cluster. Nucleic Acids Res (2014) 0.79
A Platform for Discovery and Quantification of Modified Ribonucleosides in RNA: Application to Stress-Induced Reprogramming of tRNA Modifications. Methods Enzymol (2015) 0.79
Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a β-strand sliding mechanism. Nucleic Acids Res (2017) 0.75
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Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium. Cell (1985) 12.51
Revised methods for the Salmonella mutagenicity test. Mutat Res (1983) 11.60
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The free radical theory of aging matures. Physiol Rev (1998) 9.83
Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. Science (1983) 9.38
Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection. Proc Natl Acad Sci U S A (1973) 9.09
Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals. Proc Natl Acad Sci U S A (1975) 8.66
An improved bacterial test system for the detection and classification of mutagens and carcinogens. Proc Natl Acad Sci U S A (1973) 8.45
Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis. Proc Natl Acad Sci U S A (1981) 8.45
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Transcriptional regulator of oxidative stress-inducible genes: direct activation by oxidation. Science (1990) 5.53
Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc Natl Acad Sci U S A (1988) 5.52
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Single nocturnal dose of an H2 receptor antagonist for the treatment of duodenal ulcer. Gut (1983) 4.47
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Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage. Proc Natl Acad Sci U S A (1997) 4.38
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Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine. Proc Natl Acad Sci U S A (1990) 4.06
Ascorbate is an outstanding antioxidant in human blood plasma. Proc Natl Acad Sci U S A (1989) 4.02
Oxidative decay of DNA. J Biol Chem (1997) 3.94
Histidine regulatory mutants in Salmonella typhimurium 3. A class of regulatory mutants deficient in tRNA for histidine. J Mol Biol (1966) 3.80
OxyR, a positive regulator of hydrogen peroxide-inducible genes in Escherichia coli and Salmonella typhimurium, is homologous to a family of bacterial regulatory proteins. Proc Natl Acad Sci U S A (1989) 3.77
An alkyl hydroperoxide reductase from Salmonella typhimurium involved in the defense of DNA against oxidative damage. Purification and properties. J Biol Chem (1989) 3.74
AppppA, heat-shock stress, and cell oxidation. Proc Natl Acad Sci U S A (1983) 3.68
Carcinogens as frameshift mutagens: metabolites and derivatives of 2-acetylaminofluorene and other aromatic amine carcinogens. Proc Natl Acad Sci U S A (1972) 3.61
Histidine regulation in Salmonella typhimurium. XI. The percentage of transfer RNA His charged in vivo and its relation to the repression of the histidine operon. J Mol Biol (1972) 3.60
[Mutant tRNA His ineffective in repression and lacking two pseudouridine modifications]. Nat New Biol (1972) 3.57
Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion. Proc Natl Acad Sci U S A (1976) 3.46
The leader mRNA of the histidine attenuator region resembles tRNAHis: possible general regulatory implications. Proc Natl Acad Sci U S A (1983) 3.43
In vivo studies on the interaction of RNA polymerase-sigma 54 with the Klebsiella pneumoniae and Rhizobium meliloti nifH promoters. The role of NifA in the formation of an open promoter complex. J Mol Biol (1989) 3.43
Antioxidant defenses and lipid peroxidation in human blood plasma. Proc Natl Acad Sci U S A (1988) 3.42
Epoxides of carcinogenic polycyclic hydrocarbons are frameshift mutagens. Science (1972) 3.42
Adenosine 3':5'-cyclic monophosphate concentration in the bacterial host regulates the viral decision between lysogeny and lysis. Proc Natl Acad Sci U S A (1971) 3.39
Positive selection of mutants with deletions of the gal-chl region of the Salmonella chromosome as a screening procedure for mutagens that cause deletions. J Bacteriol (1975) 3.37
An alkyl hydroperoxide reductase induced by oxidative stress in Salmonella typhimurium and Escherichia coli: genetic characterization and cloning of ahp. J Bacteriol (1989) 3.37
Antioxidant activity of albumin-bound bilirubin. Proc Natl Acad Sci U S A (1987) 3.35
AppppA and related adenylylated nucleotides are synthesized as a consequence of oxidation stress. Cell (1984) 3.25
Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radic Biol Med (2005) 3.13
Regulation of nonspecific acid phosphatase in Salmonella: phoN and phoP genes. J Bacteriol (1979) 3.09
Guanosine 5'-diphosphate 3'-diphosphate (ppGpp): positive effector for histidine operon transcription and general signal for amino-acid deficiency. Proc Natl Acad Sci U S A (1975) 3.05
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gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am J Clin Nutr (2001) 2.91
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Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay. Anal Biochem (1983) 2.85
Thymine glycol and thymidine glycol in human and rat urine: a possible assay for oxidative DNA damage. Proc Natl Acad Sci U S A (1984) 2.82
Regulation of two phosphatases and a cyclic phosphodiesterase of Salmonella typhimurium. J Bacteriol (1977) 2.68
A new Salmonella tester strain (TA102) with A X T base pairs at the site of mutation detects oxidative mutagens. Proc Natl Acad Sci U S A (1982) 2.67
Oxidative damage to DNA: relation to species metabolic rate and life span. Proc Natl Acad Sci U S A (1988) 2.62
Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. Proc Natl Acad Sci U S A (1994) 2.55
Hair dyes are mutagenic: identification of a variety of mutagenic ingredients. Proc Natl Acad Sci U S A (1975) 2.55
Identification and molecular analysis of oxyR-regulated promoters important for the bacterial adaptation to oxidative stress. J Mol Biol (1989) 2.52
Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium. Proc Natl Acad Sci U S A (1987) 2.51
Mode of action of the herbicide, 3-amino-1,2,4-triazole(amitrole): inhibition of an enzyme of histidine biosynthesis. Arch Biochem Biophys (1965) 2.46
Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication. Biochem J (1998) 2.41
Biosynthesis of pseudouridine in transfer ribonucleic acid. J Biol Chem (1974) 2.36
Effect of the alpha-hydrazino analogue of histidine on histidine transport and arginine biosynthesis. J Biol Chem (1966) 2.35
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Pleiotropy of hisT mutants blocked in pseudouridine synthesis in tRNA: leucine and isoleucine-valine operons. Proc Natl Acad Sci U S A (1974) 2.31
Histidine regulatory mutants in Salmonella typhimurium. IV. A positive selection for polar histidine-requiring mutants from histidine operator constitutive mutants. J Mol Biol (1967) 2.30
gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells. Proc Natl Acad Sci U S A (2000) 2.29
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Cisplatin and gemcitabine treatment for malignant mesothelioma: a phase II study. J Clin Oncol (1999) 2.25
Illicit transport: the oligopeptide permease. Proc Natl Acad Sci U S A (1973) 2.22
Identifying environmental chemicals causing mutations and cancer. Science (1979) 2.22
NifA-dependent in vivo protection demonstrates that the upstream activator sequence of nif promoters is a protein binding site. Proc Natl Acad Sci U S A (1988) 2.10
Ranking possible carcinogenic hazards. Science (1987) 2.06
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Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain. Proc Natl Acad Sci U S A (1988) 2.04
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The DNA-binding domain of the transcriptional activator protein NifA resides in its carboxy terminus, recognises the upstream activator sequences of nif promoters and can be separated from the positive control function of NifA. Nucleic Acids Res (1988) 1.89
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