Published in J Immunol on October 01, 1984
BCG induced CD4+ cytotoxic T cells from BCG vaccinated healthy subjects: relation between cytotoxicity and suppression in vitro. Clin Exp Immunol (1987) 1.60
Autocrine growth stimulation of a human T-cell lymphoma line by interleukin 2. Proc Natl Acad Sci U S A (1985) 1.32
Use of an Epstein-Barr virus episomal replicon for anti-sense RNA-mediated gene inhibition in a human cytotoxic T-cell clone. Proc Natl Acad Sci U S A (1988) 1.15
The T-cell mediated immune response to Schistosoma mansoni. I. Generation of stage-specific, MHC-restricted proliferative T-cell clones to soluble egg antigens. Immunology (1985) 0.89
Interleukin 2 mediates the inhibition of oligodendrocyte progenitor cell proliferation in vitro. Proc Natl Acad Sci U S A (1986) 0.88
Regulation of interleukin 2 receptors on T cells from multiple sclerosis patients. Proc Natl Acad Sci U S A (1986) 0.86
Production of Listeria-specific rat T-cell clones and role of interleukin-2 receptors in regulation of Listeria-dependent T-cell clone growth in vitro. Infect Immun (1985) 0.84
Functional consequences of anti-sense RNA-mediated inhibition of CD8 surface expression in a human T cell clone. J Exp Med (1988) 0.83
Impaired interleukin-2 receptor expression on lymphocytes from patients with chronic active hepatitis type B. Korean J Intern Med (1989) 0.77
Use of ultraviolet-light irradiated multiple myeloma cells as immunogens to generate tumor-specific cytolytic T lymphocytes. J Immune Based Ther Vaccines (2008) 0.75
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell (1995) 11.86
Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science (1997) 11.48
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science (1997) 8.81
PI3K: downstream AKTion blocks apoptosis. Cell (1997) 7.73
Isolation of multipotent adult stem cells from the dermis of mammalian skin. Nat Cell Biol (2001) 7.20
Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature (1985) 7.10
In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific. J Exp Med (1984) 6.27
Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity. Cell (1987) 5.87
Differences in antigen presentation to MHC class I-and class II-restricted influenza virus-specific cytolytic T lymphocyte clones. J Exp Med (1986) 5.11
Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor. Cell (1989) 4.86
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor. Nature (1991) 4.44
Immunologic recognition of influenza virus-infected cells. I. Generation of a virus-strain specific and a cross-reactive subpopulation of cytotoxic T cells in the response to type A influenza viruses of different subtypes. Cell Immunol (1977) 3.60
Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity. Proc Natl Acad Sci U S A (1988) 3.52
A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine. Mol Cell Biol (1991) 3.20
An anti-apoptotic role for the p53 family member, p73, during developmental neuron death. Science (2000) 3.12
Response to influenza infection in mice with a targeted disruption in the interferon gamma gene. J Exp Med (1993) 2.88
Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation. Proc Natl Acad Sci U S A (1992) 2.86
Heterogeneity and specificity of cloned lines of influenza-virus specific cytotoxic T lymphocytes. J Exp Med (1981) 2.71
Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex. Mol Cell Biol (1990) 2.71
Immunologic recognition of influenza virus-infected cells. II. Expression of influenza A matrix protein on the infected cell surface and its role in recognition by cross-reactive cytotoxic T cells. J Exp Med (1977) 2.68
Resistance to and recovery from lethal influenza virus infection in B lymphocyte-deficient mice. J Exp Med (1997) 2.67
Antigen presentation pathways to class I and class II MHC-restricted T lymphocytes. Immunol Rev (1987) 2.64
Interleukin 3-dependent survival by the Akt protein kinase. Proc Natl Acad Sci U S A (1997) 2.64
Phosphatidylinositol metabolism and polyoma-mediated transformation. Proc Natl Acad Sci U S A (1986) 2.62
Influenza virus-specific CD4+ T helper type 2 T lymphocytes do not promote recovery from experimental virus infection. J Exp Med (1994) 2.53
The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor. Cell (1991) 2.46
Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses. Neuron (1994) 2.44
Virus-specific CD8+ T lymphocytes downregulate T helper cell type 2 cytokine secretion and pulmonary eosinophilia during experimental murine respiratory syncytial virus infection. J Exp Med (1997) 2.40
Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation. J Clin Invest (2000) 2.25
Platelet alpha granules contain a growth factor for fibroblasts. Blood (1979) 2.18
Cytotoxic T lymphocyte recognition of the influenza hemagglutinin gene product expressed by DNA-mediated gene transfer. J Exp Med (1984) 2.10
Neurotrophin-5: a novel neurotrophic factor that activates trk and trkB. Neuron (1991) 2.03
AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation. Mol Cell Biol (1995) 2.03
Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation. Neuron (1992) 1.96
Expression of a murine polyclonal T cell receptor marker correlates with the use of specific members of the V beta 8 gene segment subfamily. J Exp Med (1987) 1.96
The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase. Neuron (2000) 1.95
Role of viral infectivity in the induction of influenza virus-specific cytotoxic T cells. J Exp Med (1978) 1.91
The analysis of the monoclonal immune response to influenza virus. I. Production of monoclonal anti-viral antibodies in vitro. Eur J Immunol (1975) 1.81
Immunopathology in RSV infection is mediated by a discrete oligoclonal subset of antigen-specific CD4(+) T cells. Immunity (2001) 1.69
Class I major histocompatibility complex-restricted cytolytic T lymphocytes recognize a limited number of sites on the influenza hemagglutinin. Proc Natl Acad Sci U S A (1989) 1.68
Recognition of pre-processed endogenous antigen by class I but not class II MHC-restricted T cells. Nature (1989) 1.67
Specificity of cytotoxicity T cells directed to influenza virus hemagglutinin. J Exp Med (1979) 1.64
On the role of the transmembrane anchor sequence of influenza hemagglutinin in target cell recognition by class I MHC-restricted, hemagglutinin-specific cytolytic T lymphocytes. J Exp Med (1987) 1.58
Role of T-cell function in recovery from murine influenza infection. Cell Immunol (1979) 1.57
Structural and functional consequences of alveolar cell recognition by CD8(+) T lymphocytes in experimental lung disease. J Clin Invest (1998) 1.54
Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene. Proc Natl Acad Sci U S A (1991) 1.53
Antigen presentation: structural themes and functional variations. Immunol Today (1991) 1.53
The attachment (G) glycoprotein of respiratory syncytial virus contains a single immunodominant epitope that elicits both Th1 and Th2 CD4+ T cell responses. J Immunol (2000) 1.50
Influenza virus-specific human cytotoxic T cell clones: heterogeneity in antigenic specificity and restriction by class II MHC products. Cell Immunol (1984) 1.50
Neurotrophin and neurotrophin receptors in vascular smooth muscle cells. Regulation of expression in response to injury. Am J Pathol (1995) 1.49
Virus-specific memory and effector T lymphocytes exhibit different cytokine responses to antigens during experimental murine respiratory syncytial virus infection. J Virol (1997) 1.48
Neurotrophin signalling pathways regulating neuronal apoptosis. Cell Mol Life Sci (2001) 1.46
Expression of specific cytolytic activity by H-2I region-restricted, influenza virus-specific T lymphocyte clones. J Exp Med (1985) 1.46
Expression of brain-derived neurotrophic factor and p145TrkB affects survival, differentiation, and invasiveness of human neuroblastoma cells. Cancer Res (1995) 1.45
Retrovirus shuttle vector for study of kinase activities of pp60c-src synthesized in vitro and overproduced in vivo. Mol Cell Biol (1986) 1.45
Nerve growth factor promotes the activation of phosphatidylinositol 3-kinase and its association with the trk tyrosine kinase. J Biol Chem (1992) 1.44
NGF-stimulated retrograde transport of trkA in the mammalian nervous system. J Cell Biol (1995) 1.36
p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors. J Cell Biol (1998) 1.36
Regulation of TrkA and ChAT expression in developing rat basal forebrain: evidence that both exogenous and endogenous NGF regulate differentiation of cholinergic neurons. J Neurosci (1995) 1.35
Antigen form influences induction and frequency of influenza-specific class I and class II MHC-restricted cytolytic T lymphocytes. J Immunol (1988) 1.35
Simultaneous expression of H-2-restricted and alloreactive recognition by a cloned line of influenza virus-specific cytotoxic T lymphocytes. J Exp Med (1981) 1.34
Early events in neurotrophin signalling via Trk and p75 receptors. Curr Opin Neurobiol (1995) 1.33
Visualization and characterization of respiratory syncytial virus F-specific CD8(+) T cells during experimental virus infection. J Immunol (2001) 1.33
BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain. J Neurosci (2000) 1.32
Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival. J Cell Biol (1999) 1.32
Fine specificity and antigen receptor expression among influenza virus-specific cytolytic T lymphocyte clones. J Immunol (1986) 1.29
p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells. Neuron (1994) 1.28
Why can't cytotoxic T cells handle HIV? Proc Natl Acad Sci U S A (1995) 1.27
On Trk for retrograde signaling. Neuron (2001) 1.27
Human natural killer cells mediate killing of intracellular Mycobacterium tuberculosis H37Rv via granule-independent mechanisms. Infect Immun (2001) 1.27
Developmental and mature expression of full-length and truncated TrkB receptors in the rat forebrain. J Comp Neurol (1996) 1.26
The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor. J Biol Chem (2001) 1.25
Induction of Th-1 and Th-2 responses by respiratory syncytial virus attachment glycoprotein is epitope and major histocompatibility complex independent. J Virol (1999) 1.25
Regulated neurotrophin receptor responsiveness during neuronal migrationand early differentiation. J Neurosci (1994) 1.23
Differential utilization of Trk autophosphorylation sites. J Biol Chem (1996) 1.22
CD8+ T cell recognition of an endogenously processed epitope is regulated primarily by residues within the epitope. J Exp Med (1992) 1.17
Partial activation of CD8+ T cells by a self-derived peptide. Nature (1995) 1.17
Autophosphorylation of activation loop tyrosines regulates signaling by the TRK nerve growth factor receptor. J Biol Chem (1997) 1.17
Use of an Epstein-Barr virus episomal replicon for anti-sense RNA-mediated gene inhibition in a human cytotoxic T-cell clone. Proc Natl Acad Sci U S A (1988) 1.15
Induction by NGF of meiotic maturation of Xenopus oocytes expressing the trk proto-oncogene product. Science (1991) 1.11
Class I major histocompatibility complex-restricted T lymphocyte recognition of the influenza hemagglutinin. Overlap between class I cytotoxic T lymphocytes and antibody sites. J Exp Med (1989) 1.11