Published in J Exp Med on January 01, 1987
Developmentally regulated expression of T cell receptor beta chain variable domains in immature thymocytes. J Exp Med (1987) 2.35
Deletion of autospecific T cells in T cell receptor (TCR) transgenic mice spares cells with normal TCR levels and low levels of CD8 molecules. J Exp Med (1989) 2.35
Correlation of T cell receptor V beta gene family with MHC restriction. J Exp Med (1987) 2.04
T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice. EMBO J (1989) 1.94
Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4. Proc Natl Acad Sci U S A (1995) 1.94
Predominant expression of a T cell receptor V beta gene subfamily in autoimmune encephalomyelitis. J Exp Med (1988) 1.89
Two monoclonal rat antibodies with specificity for the beta-chain variable region V beta 6 of the murine T-cell receptor. Proc Natl Acad Sci U S A (1988) 1.75
T cell antigen receptor expression in athymic (nu/nu) mice. Evidence for an oligoclonal beta chain repertoire. J Exp Med (1987) 1.61
Possible role of V beta T cell receptor genes in susceptibility to collagen-induced arthritis in mice. J Exp Med (1988) 1.55
Multiple discrete encephalitogenic epitopes of the autoantigen myelin basic protein include a determinant for I-E class II-restricted T cells. J Exp Med (1988) 1.48
Failure of clonal deletion in neonatally thymectomized mice: tolerance is preserved through clonal anergy. J Exp Med (1990) 1.42
Phenotypic properties, interleukin 2 production, and developmental origin of a "mature" subpopulation of Lyt-2- L3T4- mouse thymocytes. Proc Natl Acad Sci U S A (1987) 1.24
TCR3: a third T-cell receptor in the chicken. Proc Natl Acad Sci U S A (1989) 1.14
Constitutive tyrosine phosphorylation of the T-cell receptor (TCR) zeta subunit: regulation of TCR-associated protein tyrosine kinase activity by TCR zeta. Mol Cell Biol (1993) 1.00
A bacterially expressed single-chain Fv construct from the 2B4 T-cell receptor. Proc Natl Acad Sci U S A (1993) 0.92
Genetic dissection of T cell receptor V beta gene requirements for spontaneous murine diabetes. J Exp Med (1991) 0.91
Specific prolongation of allograft survival by a T-cell-receptor-derived peptide. Proc Natl Acad Sci U S A (1993) 0.84
Alpha-galactosylceramide promotes killing of Listeria monocytogenes within the macrophage phagosome through invariant NKT-cell activation. Infect Immun (2010) 0.83
Expression and sequences of T cell receptor beta-chain variable genes in the enlarged lymph nodes of C57BL/6-lpr/lpr mice. Clin Exp Immunol (1989) 0.79
A self-reactive class I-restricted T-cell response of H-2b mice to determinants of the V beta 8.2 domain of the T-cell receptor for antigen. Immunology (1994) 0.75
Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol (1975) 503.08
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry (1979) 180.95
Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor. J Immunol (1985) 7.90
The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J Exp Med (1984) 4.29
Murine T-cell receptor mutants with deletions of beta-chain variable region genes. Proc Natl Acad Sci U S A (1986) 3.76
The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments. Nature (1985) 3.36
Heterogeneity and specificity of cloned lines of influenza-virus specific cytotoxic T lymphocytes. J Exp Med (1981) 2.71
T-cell receptor beta-chain expression: dependence on relatively few variable region genes. Science (1985) 2.65
V beta gene polymorphism and a major polyclonal T cell receptor idiotype. Cell (1985) 1.87
T-cell receptor variable region gene usage in T-cell populations. Proc Natl Acad Sci U S A (1986) 1.56
Identification of a third type of lambda light chain in mouse immunoglobulins. Proc Natl Acad Sci U S A (1981) 1.31
Fine specificity and antigen receptor expression among influenza virus-specific cytolytic T lymphocyte clones. J Immunol (1986) 1.29
The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype. J Immunol (1985) 1.24
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
A common language for physical mapping of the human genome. Science (1989) 17.36
Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. Science (2001) 17.11
A physical map of the human genome. Nature (2001) 12.39
Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo. Science (1990) 12.13
An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH. Cell (1980) 10.35
Two mRNAs can be produced from a single immunoglobulin mu gene by alternative RNA processing pathways. Cell (1980) 9.86
DNA diagnostics--molecular techniques and automation. Science (1988) 8.85
Gene families: the taxonomy of protein paralogs and chimeras. Science (1997) 8.80
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell (1996) 8.77
A new approach to decoding life: systems biology. Annu Rev Genomics Hum Genet (2001) 7.79
A ligase-mediated gene detection technique. Science (1988) 7.61
Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity (1994) 7.22
Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1. Nat Genet (1997) 6.66
Two mRNAs with different 3' ends encode membrane-bound and secreted forms of immunoglobulin mu chain. Cell (1980) 6.32
In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific. J Exp Med (1984) 6.27
A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody. Cell (1981) 5.87
Genome sequence of Halobacterium species NRC-1. Proc Natl Acad Sci U S A (2000) 5.87
The organization, expression, and evolution of antibody genes and other multigene families. Annu Rev Genet (1975) 5.87
A pseudogene homologous to mouse transplantation antigens: transplantation antigens are encoded by eight exons that correlate with protein domains. Cell (1981) 5.43
A molecular map of the immune response region from the major histocompatibility complex of the mouse. Nature (1982) 5.12
Differences in antigen presentation to MHC class I-and class II-restricted influenza virus-specific cytolytic T lymphocyte clones. J Exp Med (1986) 5.11
Three cDNA clones encoding mouse transplantation antigens: homology to immunoglobulin genes. Cell (1981) 4.95
Pairwise end sequencing: a unified approach to genomic mapping and sequencing. Genomics (1995) 4.83
Clusters of genes encoding mouse transplantation antigens. Cell (1982) 4.71
Antibody diversity: somatic hypermutation of rearranged VH genes. Cell (1981) 4.65
A new strategy for genome sequencing. Nature (1996) 4.61
Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Cell (1993) 4.59
Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy. Cell (1988) 4.47
Genes of the major histocompatibility complex of the mouse. Annu Rev Immunol (1983) 4.44
Positive and negative selection of an antigen receptor on T cells in transgenic mice. Nature (1988) 4.02
An immunoglobulin heavy-chain gene is formed by at least two recombinational events. Nature (1980) 3.99
Striking sequence similarity over almost 100 kilobases of human and mouse T-cell receptor DNA. Nat Genet (1994) 3.88
IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts. Nature (1981) 3.86
Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice. Nature (1988) 3.82
Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2. Cancer Res (1999) 3.79
Murine T-cell receptor mutants with deletions of beta-chain variable region genes. Proc Natl Acad Sci U S A (1986) 3.76
Immunologic recognition of influenza virus-infected cells. I. Generation of a virus-strain specific and a cross-reactive subpopulation of cytotoxic T cells in the response to type A influenza viruses of different subtypes. Cell Immunol (1977) 3.60
Silkmoth chorion proteins: sequence analysis of the products of a multigene family. Proc Natl Acad Sci U S A (1978) 3.60
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing. Biochemistry (1993) 3.54
Introduced T cell receptor variable region gene segments recombine in pre-B cells: evidence that B and T cells use a common recombinase. Cell (1986) 3.51
Large-scale and automated DNA sequence determination. Science (1991) 3.45
Cell-type-specific cDNA probes and the murine I region: the localization and orientation of Ad alpha. Proc Natl Acad Sci U S A (1984) 3.43
The human T cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene. Cell (1984) 3.41
The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments. Nature (1985) 3.36
Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity (1997) 3.33
T cell antigen receptors and the immunoglobulin supergene family. Cell (1985) 3.23
Cell-cell interaction in prostate gene regulation and cytodifferentiation. Proc Natl Acad Sci U S A (1997) 3.22
Immunoglobulin heavy chain gene organization in mice: analysis of a myeloma genomic clone containing variable and alpha constant regions. Proc Natl Acad Sci U S A (1979) 3.19
The structure, rearrangement and expression of D beta gene segments of the murine T-cell antigen receptor. Nature (1984) 3.18
DNA sequence of a gene encoding a BALB/c mouse Ld transplantation antigen. Science (1982) 3.17
Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals. Immunity (1998) 3.10
Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4. J Immunol (1995) 3.06
Mechanism of antibody diversity: germ line basis for variability. Science (1970) 3.05
Predominant use of a V alpha gene segment in mouse T-cell receptors for cytochrome c. Nature (1987) 2.99
Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes. Science (1993) 2.93
Understanding the adaptation of Halobacterium species NRC-1 to its extreme environment through computational analysis of its genome sequence. Genome Res (2001) 2.92
Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1. Genome Res (1996) 2.91
Automated DNA diagnostics using an ELISA-based oligonucleotide ligation assay. Proc Natl Acad Sci U S A (1990) 2.88
Essential role for ZAP-70 in both positive and negative selection of thymocytes. Nature (1995) 2.88
Response to influenza infection in mice with a targeted disruption in the interferon gamma gene. J Exp Med (1993) 2.88
Genes of the major histocompatibility complex in mouse and man. Science (1983) 2.88
Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation. Proc Natl Acad Sci U S A (1992) 2.86
Rearrangement of genetic information may produce immunoglobulin diversity. Nature (1979) 2.84
Mechanism of antibody synthesis: size differences between mouse kappa chains. Science (1967) 2.77
Zinc-dependent structure of a single-finger domain of yeast ADR1. Science (1988) 2.76
McDonough feline sarcoma virus: characterization of the molecularly cloned provirus and its feline oncogene (v-fms). J Virol (1982) 2.76
DNA sequence determination by hybridization: a strategy for efficient large-scale sequencing. Science (1993) 2.76
Heterogeneity and specificity of cloned lines of influenza-virus specific cytotoxic T lymphocytes. J Exp Med (1981) 2.71
Immunologic recognition of influenza virus-infected cells. II. Expression of influenza A matrix protein on the infected cell surface and its role in recognition by cross-reactive cytotoxic T cells. J Exp Med (1977) 2.68
Resistance to and recovery from lethal influenza virus infection in B lymphocyte-deficient mice. J Exp Med (1997) 2.67
Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia. Proc Natl Acad Sci U S A (1994) 2.66
From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs. Proc Natl Acad Sci U S A (2001) 2.66
Dynorphin-(1-13), an extraordinarily potent opioid peptide. Proc Natl Acad Sci U S A (1979) 2.66
T-cell receptor beta-chain expression: dependence on relatively few variable region genes. Science (1985) 2.65
Antigen presentation pathways to class I and class II MHC-restricted T lymphocytes. Immunol Rev (1987) 2.64
The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. Science (1996) 2.62
cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties. Proc Natl Acad Sci U S A (1988) 2.59
Influenza virus-specific CD4+ T helper type 2 T lymphocytes do not promote recovery from experimental virus infection. J Exp Med (1994) 2.53
Mouse Cmu heavy chain immunoglobulin gene segment contains three intervening sequences separating domains. Nature (1980) 2.52
Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate. EMBO J (1990) 2.52
The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development. Genes Dev (2000) 2.49
Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer. Nature (1982) 2.48
Molecular basis of a mouse strain-specific anti-hapten response. Cell (1983) 2.48
Comparative hybridization of an array of 21,500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas. Gene (1999) 2.45
Messenger RNA translation state: the second dimension of high-throughput expression screening. Proc Natl Acad Sci U S A (1999) 2.42
Virus-specific CD8+ T lymphocytes downregulate T helper cell type 2 cytokine secretion and pulmonary eosinophilia during experimental murine respiratory syncytial virus infection. J Exp Med (1997) 2.40
Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas. Science (1982) 2.40
Genomic organization of the genes encoding mouse T-cell receptor alpha-chain. Nature (1985) 2.40
Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans. Blood (1998) 2.33
Direct evidence for chromosomal inversion during T-cell receptor beta-gene rearrangements. Nature (1986) 2.33
Rearrangement and transcription of the beta-chain genes of the T-cell antigen receptor in different types of murine lymphocytes. Nature (1985) 2.29