Published in Annu Rev Immunol on January 01, 1984
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Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ. J Exp Med (1990) 5.35
Differences in antigen presentation to MHC class I-and class II-restricted influenza virus-specific cytolytic T lymphocyte clones. J Exp Med (1986) 5.11
T-cell antigenic sites tend to be amphipathic structures. Proc Natl Acad Sci U S A (1985) 5.05
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Role for intracellular proteases in the processing and transport of class II HLA antigens. Proc Natl Acad Sci U S A (1988) 2.64
Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain. J Exp Med (1986) 2.55
Dendritic cells are the principal cells in mouse spleen bearing immunogenic fragments of foreign proteins. J Exp Med (1990) 2.54
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An antigen-independent contact mechanism as an early step in T cell-proliferative responses to dendritic cells. J Exp Med (1989) 2.15
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An endogenous processing pathway in vaccinia virus-infected cells for presentation of cytoplasmic antigens to class II-restricted T cells. J Exp Med (1990) 1.94
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Class I major histocompatibility complex-restricted cytolytic T lymphocytes recognize a limited number of sites on the influenza hemagglutinin. Proc Natl Acad Sci U S A (1989) 1.68
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T lymphocytes synthesize and export heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor, mitogens for vascular cells and fibroblasts: differential production and release by CD4+ and CD8+ T cells. Proc Natl Acad Sci U S A (1994) 1.68
Isolation and characterization of antigen-presenting dendritic cells from the mouse intestinal lamina propria. Immunology (1990) 1.63
The role of macrophages in T cell-mediated autoimmune diabetes in nonobese diabetic mice. J Exp Med (1999) 1.58
Influences of antigen processing on the expression of the T cell repertoire. Evidence for MHC-specific hindering structures on the products of processing. J Exp Med (1988) 1.50
Invariant chain trimers are sequestered in the rough endoplasmic reticulum in the absence of association with HLA class II antigens. J Cell Biol (1990) 1.49
Direct evidence for functional self-protein/Ia-molecule complexes in vivo. Proc Natl Acad Sci U S A (1988) 1.48
Sequential Immune Responses: The Weapons of Immunity. J Innate Immun (2015) 1.47
Induced differentiation of a transformed clone of Ly-1+ B cells by clonal T cells and antigen. Proc Natl Acad Sci U S A (1986) 1.46
Structure and function of the T cell antigen receptor. J Clin Invest (1990) 1.45
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T cells sensitized to synthetic HLA-DR3 peptide give evidence of continuous presentation of denatured HLA-DR3 molecules by HLA-DP. J Exp Med (1989) 1.43
Endocytosis and recycling of specific antigen by human B cell lines. EMBO J (1988) 1.42
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Role of endogenous gamma interferon in host response to infection with blood-stage Plasmodium chabaudi AS. Infect Immun (1990) 1.40
Persistent expression of Ia antigen and viral genome in visna-maedi virus-induced inflammatory cells. Possible role of lentivirus-induced interferon. J Exp Med (1985) 1.39
Vaccine engineering: enhancement of immunogenicity of synthetic peptide vaccines related to hepatitis in chemically defined models consisting of T- and B-cell epitopes. Proc Natl Acad Sci U S A (1989) 1.39
Mouse macrophages stimulated by recombinant gamma interferon to kill tumor cells are not bactericidal for the facultative intracellular bacterium Listeria monocytogenes. Infect Immun (1988) 1.38
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Protection against Salmonella typhi infection in mice after immunization with outer membrane proteins isolated from Salmonella typhi 9,12,d, Vi. Infect Immun (1988) 1.33
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How the thymus designs antigen-specific and self-tolerant T cell receptor sequences. Proc Natl Acad Sci U S A (2008) 1.32
Lymphokine secretion and cytotoxic activity of human CD4+ T-cell clones against Bordetella pertussis. Infect Immun (1991) 1.31
Dendritic cells, the major antigen-presenting cells of the human colonic lamina propria. Immunology (1993) 1.29
Immune modulation of metalloproteinase production in human macrophages. Selective pretranslational suppression of interstitial collagenase and stromelysin biosynthesis by interferon-gamma. J Clin Invest (1990) 1.28
Functional profile of tissue-infiltrating and circulating CD68+ cells in giant cell arteritis. Evidence for two components of the disease. J Clin Invest (1994) 1.26
Regulation of macrophage accessory cell activity by mycobacteria. II. In vitro inhibition of Ia expression by Mycobacterium microti. Clin Exp Immunol (1986) 1.25
Pairing computation with experimentation: a powerful coupling for understanding T cell signalling. Nat Rev Immunol (2010) 1.25
Identification of eight determinants in the hemagglutinin molecule of influenza virus A/PR/8/34 (H1N1) which are recognized by class II-restricted T cells from BALB/c mice. J Virol (1991) 1.24
Antigenicity and immunogenicity of an extract from the cell wall and cell membrane of Histoplasma capsulatum yeast cells. Infect Immun (1991) 1.21
Ia-transfected L-cell fibroblasts present a lysozyme peptide but not the native protein to lysozyme-specific T cells. Proc Natl Acad Sci U S A (1985) 1.21
Relative contribution of "determinant selection" and "holes in the T-cell repertoire" to T-cell responses. Proc Natl Acad Sci U S A (1989) 1.20
The generation of a 'tolerogen' after the ingestion of ovalbumin is time-dependent and unrelated to serum levels of immunoreactive antigen. Clin Exp Immunol (1990) 1.19
A juxta-membrane epitope on the human acetylcholine receptor recognized by T cells in myasthenia gravis. J Clin Invest (1988) 1.19
An evolving new paradigm: endothelial cells--conditional innate immune cells. J Hematol Oncol (2013) 1.17
Lymph-borne (veiled) dendritic cells can acquire and present intestinally administered antigens. Immunology (1991) 1.17
Dendritic cells and macrophages in the uveal tract of the normal mouse eye. Br J Ophthalmol (1999) 1.16
Monomeric IgG2a promotes maturation of bone-marrow macrophages and expression of the mannose receptor. Proc Natl Acad Sci U S A (1991) 1.15
Disease inhibition by major histocompatibility complex binding peptide analogues of disease-associated epitopes: more than blocking alone. J Exp Med (1992) 1.12
Suppression of cellular immunity to Listeria monocytogenes by activated macrophages: mediation by prostaglandins. Infect Immun (1985) 1.12
Potent immunoregulatory effects of Salmonella typhi flagella on antigenic stimulation of human peripheral blood mononuclear cells. Infect Immun (1999) 1.12
Invariant chain induces B cell maturation in a process that is independent of its chaperonic activity. Proc Natl Acad Sci U S A (2002) 1.11
Class I major histocompatibility complex-restricted T lymphocyte recognition of the influenza hemagglutinin. Overlap between class I cytotoxic T lymphocytes and antibody sites. J Exp Med (1989) 1.11
Bacterial antigen immunolabeling in macrophages after phagocytosis and degradation of Bacillus subtilis. Infect Immun (1988) 1.09
Transferrin receptor mediates uptake and presentation of hepatitis B envelope antigen by T lymphocytes. J Exp Med (1992) 1.09
Kinetics of antigenic peptide binding to the class II major histocompatibility molecule I-Ad. Proc Natl Acad Sci U S A (1991) 1.08
Self-peptide released from class II HLA-DR1 exhibits a hydrophobic two-residue contact motif. J Exp Med (1992) 1.08
Amplification of rabies virus-induced stimulation of human T-cell lines and clones by antigen-specific antibodies. J Virol (1985) 1.06
Anatomy of a discovery: m1 and m2 macrophages. Front Immunol (2015) 1.06
Recognition of rabies and rabies-related viruses by T cells derived from human vaccine recipients. J Virol (1988) 1.05
Acquisition of cell-mediated immunity to Leishmania. II. LSH gene regulation of accessory cell function. Immunology (1988) 1.04
Cooperation between major histocompatibility complex mismatched mononuclear cells from a human chimera in the production of antigen-specific antibody. J Clin Invest (1986) 1.04
Immune aspects of sarcoidosis. Postgrad Med J (1988) 1.04
Human T-helper lymphocytes in myasthenia gravis recognize the nicotinic receptor alpha subunit. Proc Natl Acad Sci U S A (1987) 1.04
Anti-immunoglobulin augments the B-cell antigen-presentation function independently of internalization of receptor-antigen complex. Proc Natl Acad Sci U S A (1985) 1.04
Interstitial lung macrophages interact with dendritic cells to present antigenic peptides derived from particulate antigens to T cells. Immunology (1994) 1.03
Phenotypic and functional changes in alveolar macrophages contribute to the pathogenesis of pulmonary sarcoidosis. Clin Exp Immunol (1988) 1.03
Platelet activating factor raises intracellular calcium ion concentration in macrophages. J Cell Biol (1986) 1.02
Antigen presentation by a B-cell line transfected with cloned immunoglobulin heavy- and light-chain genes specific for a defined hapten. Proc Natl Acad Sci U S A (1986) 1.02
Immune chaperone gp96 drives the contributions of macrophages to inflammatory colon tumorigenesis. Cancer Res (2013) 1.02
Differential expression and regulation of MHC products in the endocrine and exocrine cells of the human pancreas. Clin Exp Immunol (1986) 1.01
Binding of immunogenic peptides to Ia histocompatibility molecules. Nature (1985) 8.39
Requirement of thymus (T) lymphocytes for resistance to listeriosis. J Exp Med (1972) 8.25
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Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proc Natl Acad Sci U S A (1993) 6.33
Immunoglobulins on the surface of lymphocytes. II. The bone marrow as the main source of lymphocytes with detectable surface-bound immunoglobulin. J Exp Med (1971) 5.43
Critical role of determinant presentation in the induction of specific responses in immunocompetent lymphocytes. J Exp Med (1973) 5.30
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Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells. Proc Natl Acad Sci U S A (1982) 4.85
The regulatory role of macrophages in antigenic stimulation. Part Two: symbiotic relationship between lymphocytes and macrophages. Adv Immunol (1981) 4.72
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The basis for the immunoregulatory role of macrophages and other accessory cells. Science (1987) 4.51
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Identification of a macrophage antigen-processing event required for I-region-restricted antigen presentation to T lymphocytes. J Immunol (1981) 3.94
Prostaglandins modulate macrophage Ia expression. Nature (1982) 3.83
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Activated macrophages induce vascular proliferation. Nature (1977) 3.74
Antigen presentation: comments on its regulation and mechanism. J Immunol (1984) 3.68
Corticosteroids inhibit murine macrophage Ia expression and interleukin 1 production. J Immunol (1982) 3.61
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