Published in Nature on November 12, 1981
Transferrin receptors in human tissues: their distribution and possible clinical relevance. J Clin Pathol (1983) 3.23
Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cell growth in vitro. Proc Natl Acad Sci U S A (1982) 2.42
The transferrin receptor and the targeted delivery of therapeutic agents against cancer. Biochim Biophys Acta (2011) 1.64
The complex role of multivalency in nanoparticles targeting the transferrin receptor for cancer therapies. J Am Chem Soc (2010) 1.63
Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen. Proc Natl Acad Sci U S A (1986) 1.56
Exposure of K562 cells to anti-receptor monoclonal antibody OKT9 results in rapid redistribution and enhanced degradation of the transferrin receptor. J Cell Biol (1986) 1.50
Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia. J Exp Med (2010) 1.39
Pseudomonas exotoxin-anti-TAC. Cell-specific immunotoxin active against cells expressing the human T cell growth factor receptor. J Clin Invest (1984) 1.13
Monoclonal antibody and an antibody-toxin conjugate to a cell surface proteoglycan of melanoma cells suppress in vivo tumor growth. Proc Natl Acad Sci U S A (1983) 1.12
Mitogenic response of canine fundic epithelial cells in short-term culture to transforming growth factor alpha and insulinlike growth factor I. J Clin Invest (1991) 1.12
Enhancement of toxicity of antitransferrin receptor antibody-Pseudomonas exotoxin conjugates by adenovirus. Proc Natl Acad Sci U S A (1983) 1.09
Molecular events contributing to cell death in malignant human hematopoietic cells elicited by an IgG3-avidin fusion protein targeting the transferrin receptor. Blood (2006) 1.05
Chemotherapy by intravenous administration of conjugates of daunomycin with monoclonal and conventional anti-rat alpha-fetoprotein antibodies. Proc Natl Acad Sci U S A (1982) 1.03
Selective cytotoxicity against human tumour cells by a vindesine-monoclonal antibody conjugate. Br J Cancer (1983) 1.02
Antitumor effects of an immunotoxin made with Pseudomonas exotoxin in a nude mouse model of human ovarian cancer. Proc Natl Acad Sci U S A (1986) 1.01
Therapy of murine leukemia with monoclonal antibody against a normal differentiation antigen. J Exp Med (1983) 1.01
Use of antibodies and immunoconjugates for the therapy of more accessible cancers. Adv Drug Deliv Rev (2008) 1.00
Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma. J Clin Invest (2010) 1.00
Selection of cell lines resistant to anti-transferrin receptor antibody: evidence for a mutation in transferrin receptor. Mol Cell Biol (1984) 0.97
A novel transferrin receptor-targeted hybrid peptide disintegrates cancer cell membrane to induce rapid killing of cancer cells. BMC Cancer (2011) 0.97
In vivo therapy of a murine B cell tumor (BCL1) using antibody-ricin A chain immunotoxins. J Exp Med (1982) 0.96
Demonstration of an epitope of the transferrin receptor in human cervical epithelium--a potentially useful cell marker. J Clin Pathol (1984) 0.92
Toxin-based targeted therapy for malignant brain tumors. Clin Dev Immunol (2012) 0.91
Ley specific antibody with potent anti-tumor activity is internalized and degraded in lysosomes. Am J Pathol (1993) 0.88
Differential Antitumor Effects of IgG and IgM Monoclonal Antibodies and Their Synthetic Complementarity-Determining Regions Directed to New Targets of B16F10-Nex2 Melanoma Cells. Transl Oncol (2010) 0.87
Use of ribosome-inactivating proteins from Sambucus for the construction of immunotoxins and conjugates for cancer therapy. Toxins (Basel) (2011) 0.86
Construction and high cytoplasmic expression of a tumoricidal single-chain antibody against hepatocellular carcinoma. BMC Biotechnol (2002) 0.82
Diltiazem inhibits transferrin receptor expression and causes G1 arrest in normal and neoplastic T cells. Mol Cell Biol (1986) 0.77
Monoclonal antibodies--therapeutic and diagnostic uses in malignancy. West J Med (1985) 0.76
Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells. J Cell Biol (1983) 6.17
The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipid. Cell (1982) 4.66
Human cell surface glycoprotein related to cell proliferation is the receptor for transferrin. Proc Natl Acad Sci U S A (1981) 4.34
Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis. Cell (1990) 3.75
Cross-linking of human T cell receptor proteins: association between the T cell idiotype beta subunit and the T3 glycoprotein heavy subunit. Cell (1985) 3.64
Interspecies spleen-myeloma hybrid producing monoclonal antibodies against mouse lymphocyte surface glycoprotein, T200. J Exp Med (1978) 3.54
Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization. J Cell Biol (1990) 3.24
Transferrin receptors in human tissues: their distribution and possible clinical relevance. J Clin Pathol (1983) 3.23
In migrating fibroblasts, recycling receptors are concentrated in narrow tubules in the pericentriolar area, and then routed to the plasma membrane of the leading lamella. J Cell Biol (1994) 3.19
Structural variants of human T200 glycoprotein (leukocyte-common antigen). EMBO J (1987) 3.19
Biochemical characterization and cellular distribution of a polymorphic, murine cell-surface glycoprotein expressed on lymphoid tissues. Immunogenetics (1982) 3.18
Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines. Proc Natl Acad Sci U S A (1989) 2.99
In polarized MDCK cells basolateral vesicles arise from clathrin-gamma-adaptin-coated domains on endosomal tubules. J Cell Biol (1998) 2.95
Biosynthesis of the human transferrin receptor in cultured cells. J Biol Chem (1981) 2.83
Differences in the surface proteins of mouse B and T cells. Proc Natl Acad Sci U S A (1975) 2.78
Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1. J Exp Med (1981) 2.66
Detection of a novel human class II HLA antigen. Nature (1983) 2.61
Human homologue of murine T200 glycoprotein. J Exp Med (1980) 2.57
Covalent binding of fatty acid to the transferrin receptor in cultured human cells. J Biol Chem (1981) 2.51
Effects of cytotoxic monoclonal antibody specific for T200 glycoprotein on functional lymphoid cell populations. Cell Immunol (1980) 2.47
Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cell growth in vitro. Proc Natl Acad Sci U S A (1982) 2.42
Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation. Proc Natl Acad Sci U S A (1989) 2.15
Disposition of T200 glycoprotein in the plasma membrane of a murine lymphoma cell line. J Biol Chem (1980) 2.01
Apical and basolateral endosomes of MDCK cells are interconnected and contain a polarized sorting mechanism. J Cell Biol (1996) 1.97
Human cell-surface glycoprotein with unusual properties. Nature (1980) 1.94
Transferrin receptors promote the formation of clathrin lattices. Cell (1991) 1.91
Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors. J Biol Chem (1993) 1.88
B-cell variant of mouse T200 (Ly-5): evidence for alternative mRNA splicing. Proc Natl Acad Sci U S A (1987) 1.85
Immunological properties of murine thymus-dependent lymphocyte surface glycoproteins. Eur J Immunol (1976) 1.79
Structural requirements for basolateral sorting of the human transferrin receptor in the biosynthetic and endocytic pathways of Madin-Darby canine kidney cells. J Cell Biol (1997) 1.78
Monoclonal antibodies against defined epitopes of the human transferrin receptor cytoplasmic tail. Biochim Biophys Acta (1992) 1.76
Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment. J Cell Biol (1994) 1.73
Identification and characterization of the human Pgp-1 glycoprotein. Immunogenetics (1986) 1.69
T200 cell surface glycoprotein of the mouse. Polymorphism defined by the Ly-5 system of alloantigens. J Exp Med (1980) 1.66
The synthesis and properties of T25 blycoprotein in Thy-1-negative mutant lymphoma cells. Cell (1978) 1.59
Structure of the lipid-linked oligosaccharides that accumulate in class E Thy-1-negative mutant lymphomas. Cell (1979) 1.52
Identification of the intermolecular disulfide bonds of the human transferrin receptor and its lipid-attachment site. EMBO J (1987) 1.48
Murine cell surface transferrin receptor: studies with an anti-receptor monoclonal antibody. J Cell Physiol (1982) 1.42
Isolation and chemical characterization of a mitogenic lectin from Pisum sativum. J Biol Chem (1974) 1.42
YTRF is the conserved internalization signal of the transferrin receptor, and a second YTRF signal at position 31-34 enhances endocytosis. J Biol Chem (1993) 1.40
Induction of expression and phosphorylation of the human interleukin 2 receptor by a phorbol diester. J Biol Chem (1984) 1.40
Sorting mechanisms regulating membrane protein traffic in the apical transcytotic pathway of polarized MDCK cells. J Cell Biol (1998) 1.39
Different classes of T lymphocytes have different mRNAs for the leukocyte-common antigen, T200. J Exp Med (1986) 1.39
Structural heterogeneity of human Pgp-1 and its relationship with p85. Immunogenetics (1988) 1.37
Transplanted LDL and mannose-6-phosphate receptor internalization signals promote high-efficiency endocytosis of the transferrin receptor. EMBO J (1991) 1.34
Transferrin receptors: structure and function. Biochem Pharmacol (1984) 1.34
p180, a novel recycling transmembrane glycoprotein with restricted cell type expression. Mol Cell Biol (1990) 1.28
Genetic characterization of a polymorphic murine cell-surface glycoprotein. Immunogenetics (1982) 1.28
Transmembrane domain of CD44 is required for its detergent insolubility in fibroblasts. J Cell Sci (1995) 1.27
Thymocyte subpopulation enriched for progenitors with an unrearranged T-cell receptor beta-chain gene. Nature (1985) 1.24
Combinations of anti-transferrin receptor monoclonal antibodies inhibit human tumor cell growth in vitro and in vivo: evidence for synergistic antiproliferative effects. Cancer Res (1990) 1.24
Identification of lymphocyte integral membrane proteins as substrates for protein kinase C. Phosphorylation of the interleukin-2 receptor, class I HLA antigens, and T200 glycoprotein. J Biol Chem (1986) 1.24
Coclustering CD45 with CD4 or CD8 alters the phosphorylation and kinase activity of p56lck. J Exp Med (1990) 1.23
Mouse T-cell surface glycoprotein recognised by heterologous anti-thymocyte sera and its relationship to Thy-1 antigen. Nature (1975) 1.23
Expression of Thy-1 glycoprotein on lectin-resistant lymphoma cell lines. Eur J Immunol (1978) 1.22
Characterization of sorting signals in the beta-amyloid precursor protein cytoplasmic domain. J Biol Chem (1995) 1.21
Thy-1 variants of mouse lymphomas: biochemical characterization of the genetic defect. Cell (1975) 1.20
Identification of the alternatively spliced exons of murine CD45 (T200) required for reactivity with B220 and other T200-restricted antibodies. J Exp Med (1989) 1.20
A mouse lymphoma cell line resistant to the leukoagglutinating lectin from Phaseolus vulgaris is deficient in UDP-GlcNAc: alpha-D-mannoside beta 1,6 N-acetylglucosaminyltransferase. J Biol Chem (1982) 1.16
Changes in gene expression induced by a phorbol diester: expression of IL 2 receptor, T3, and T cell antigen receptor. J Immunol (1987) 1.16
Hyper IgE (Job's) syndrome: a primary immune deficiency with oral manifestations. Oral Dis (2008) 1.12
Preliminary characterization of two thymus-dependent xenoantigens from mouse lymphocytes. Biochem J (1977) 1.12
A lectin-resistant mouse lymphoma cell line is deficient in glucosidase II, a glycoprotein-processing enzyme. J Biol Chem (1982) 1.12
Abnormal lipid-linked oligosaccharides in class E Thy-1-negative mutant lymphomas. Cell (1979) 1.11
Enhancement of toxicity of antitransferrin receptor antibody-Pseudomonas exotoxin conjugates by adenovirus. Proc Natl Acad Sci U S A (1983) 1.09
Oral and dental phenotype of dyskeratosis congenita. Oral Dis (2008) 1.08
Structure and function of transferrin receptors and their relationship to cell growth. Biochem Soc Symp (1986) 1.07
Modulation of p36 phosphorylation in human cells: studies using anti-p36 monoclonal antibodies. Mol Cell Biol (1986) 1.02
Negative regulation of CD45 protein tyrosine phosphatase activity by ionomycin in T cells. Science (1991) 1.02
High molecular weight lymphocyte surface proteins are structurally related and are expressed on different cell populations at different times during lymphocyte maturation and differentiation. J Immunol (1982) 1.01
Surface molecules of cultured human lymphoid cells. Eur J Immunol (1976) 1.01
Mitogenic properties of lectin and its chemical dervatives. Proc Natl Acad Sci U S A (1973) 0.99
Monoclonal antibody to a membrane glycoprotein inhibits the acrosome reaction and associated Ca2+ and H+ fluxes of sea urchin sperm. Cell (1985) 0.98
Characterization of the human transferrin receptor produced in a baculovirus expression system. J Biol Chem (1988) 0.98
Monoclonal antibodies to a human T-cell antigen and Ia-like antigen in the characterization of lymphoid leukemia. Transplant Proc (1981) 0.98
Nonacylated human transferrin receptors are rapidly internalized and mediate iron uptake. J Biol Chem (1990) 0.97
Rate of 59Fe uptake into brain and cerebrospinal fluid and the influence thereon of antibodies against the transferrin receptor. J Neurochem (1993) 0.96
Mutational analysis of CD45. A leukocyte-specific protein tyrosine phosphatase. J Biol Chem (1992) 0.95
Recombinant Rous sarcoma virus vectors for avian cells. Methods Cell Biol (1994) 0.94
Effect of an anti-murine transferrin receptor-ricin A conjugate on bone marrow stem and progenitor cells treated in vitro. Exp Cell Res (1984) 0.94
A monoclonal antibody useful for the differential diagnosis between malignant lymphoma and nonhematopoietic neoplasms. Cancer (1983) 0.93
Immunoglobulin-like nature of the alpha-chain of a human T-cell antigen/MHC receptor. Nature (1984) 0.93
Induction in vitro of hapten specific plaque forming cells. Nature (1970) 0.92
Human B cell line deficient in the expression of B cell-specific glycoproteins (GP 27,35). Eur J Immunol (1977) 0.91
Structural requirements for major histocompatibility complex class II invariant chain trafficking in polarized Madin-Darby canine kidney cells. J Biol Chem (1997) 0.91
Mouse lymphoma cell lines resistant to pea lectin are defective in fucose metabolism. J Biol Chem (1980) 0.90
Signal-dependent trafficking of beta-amyloid precursor protein-transferrin receptor chimeras in madin-darby canine kidney cells. J Biol Chem (1998) 0.90
Ligand-stimulated tyrosine phosphorylation of the IL-2 receptor beta chain and receptor-associated proteins. Cell Regul (1991) 0.90
Expression of variable exon A-, B-, and C-specific CD45 determinants on peripheral and thymic T cell populations. J Immunol (1992) 0.90
Functional analysis of human/chicken transferrin receptor chimeras indicates that the carboxy-terminal region is important for ligand binding. Eur J Biochem (1996) 0.89
Identification of shared antigenic determinants of the putative human T lymphocyte antigen receptor. J Exp Med (1984) 0.86
Analysis of the structural requirements for lysosomal membrane targeting using transferrin receptor chimeras. J Biol Chem (1998) 0.83
The cDNA sequence and primary structure of the chicken transferrin receptor. Gene (1991) 0.82
Effects of monoclonal antibodies that block transferrin receptor function on the in vivo growth of a syngeneic murine leukemia. Cancer Res (1987) 0.82
Immunoelectron microscopic localization of Thy-1 glycoprotein in wild type and Thy-1-negative lymphoma cells. Cell Biol Int Rep (1982) 0.81
The enhancement of a primary in vitro anti-hapten response by carrier priming. Eur J Immunol (1972) 0.81
Craniofacial and dental findings in cystinosis. Oral Dis (2010) 0.80
Transferrin receptor as a potential therapeutic target. Prog Allergy (1988) 0.80