Published in Proc Natl Acad Sci U S A on January 01, 1983
Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin. Proc Natl Acad Sci U S A (1989) 1.19
Monoclonal antibody-directed effector cells selectively lyse human melanoma cells in vitro and in vivo. Proc Natl Acad Sci U S A (1983) 1.10
Antitumor effects of an immunotoxin made with Pseudomonas exotoxin in a nude mouse model of human ovarian cancer. Proc Natl Acad Sci U S A (1986) 1.01
Ablation of human colon carcinoma in nude mice by 131I-labeled monoclonal anti-carcinoembryonic antigen antibody F(ab')2 fragments. J Clin Invest (1989) 1.00
Doxorubicin conjugated with a monoclonal antibody directed to a human melanoma-associated proteoglycan suppresses the growth of established tumor xenografts in nude mice. Proc Natl Acad Sci U S A (1988) 0.91
Eradication of established human melanoma tumors in nude mice by antibody-directed effector cells. J Exp Med (1985) 0.84
Monoclonal antibodies that prevent adhesion of B 16 melanoma cells and reduce metastases in mice: crossreaction with human tumor cells. Proc Natl Acad Sci U S A (1983) 0.83
Human uveal melanoma expresses NG2 immunoreactivity. Br J Ophthalmol (2003) 0.82
Expression of diphtheria toxin fragment A and hormone-toxin fusion proteins in toxin-resistant yeast mutants. Proc Natl Acad Sci U S A (1988) 0.82
Theranostic impact of NG2/CSPG4 proteoglycan in cancer. Theranostics (2015) 0.82
A single chain immunotoxin, targeting the melanoma-associated chondroitin sulfate proteoglycan, is a potent inducer of apoptosis in cultured human melanoma cells. Melanoma Res (2008) 0.80
Unexpected expression of the 250 kD melanoma-associated antigen in human sarcoma cells. Br J Cancer (1986) 0.79
Changes in leucocyte populations following murine bifunctional antibody infusion in colon cancer patients. Clin Exp Immunol (1991) 0.78
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-sepharose. Immunochemistry (1978) 22.56
Glycosaminoglycans and their binding to biological macromolecules. Annu Rev Biochem (1978) 4.51
Study of antibodies against human melanoma produced by somatic cell hybrids. Proc Natl Acad Sci U S A (1978) 4.24
Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis. J Biol Chem (1968) 3.81
Physiological function of connective tissue polysaccharides. Physiol Rev (1978) 3.57
A reporter group delivery system with both absolute and selective specificity for thiol groups and an improved fluorescent probe containing the 7-nitrobenzo-2-oxa-1,3-diazole moiety. Biochem J (1975) 3.17
Phase-I clinical trial of monoclonal antibody in treatment of gastrointestinal tumours. Lancet (1982) 2.25
Unique glycoprotein-proteoglycan complex defined by monoclonal antibody on human melanoma cells. Proc Natl Acad Sci U S A (1982) 2.21
Identification of a cell surface protein, p97, in human melanomas and certain other neoplasms. Proc Natl Acad Sci U S A (1980) 2.14
Selective killing of normal or neoplastic B cells by antibodies coupled to the A chain of ricin. Proc Natl Acad Sci U S A (1980) 1.85
Serotherapy of acute lymphoblastic leukemia with monoclonal antibody. Blood (1981) 1.77
Response of cutaneous T cell lymphoma to therapy with hybridoma monoclonal antibody. Lancet (1981) 1.76
Anti-transferrin receptor monoclonal antibody and toxin-antibody conjugates affect growth of human tumour cells. Nature (1981) 1.72
Inhibition of growth of colorectal carcinoma in nude mice by monoclonal antibody. Cancer Res (1980) 1.70
In vivo effects of murine hybridoma monoclonal antibody in a patient with T-cell leukemia. Blood (1981) 1.52
Neoplastic B cells as targets for antibody-ricin A chain immunotoxins. Immunol Rev (1982) 1.52
Production and characterization of monoclonal antibody to a melanoma specific glycoprotein. Hybridoma (1981) 1.42
Mouse leukemia: therapy with monoclonal antibodies against a thymus differentiation antigen. Science (1980) 1.30
Characterization and affinity labeling of the cationic phosphate-binding (nucleotide-binding) peptide located in the receptor-binding region of the B-fragment of diphtheria toxin. J Biol Chem (1980) 1.20
Biochemical characterization of human melanoma cell surfaces: dissection with monoclonal antibodies. Proc Natl Acad Sci U S A (1980) 1.12
Production of melanoma-associated antigen(s) by a defined malignant melanoma cell strain grown in chemically defined medium. Cancer Res (1976) 1.04
Monoclonal antibody-ricin A chain conjugate selectively cytotoxic for cells bearing the common acute lymphoblastic leukemia antigen. Cancer Res (1982) 1.02
Leukemic cell targeting and therapy by monoclonal antibody in a mouse model system. Cancer Res (1982) 0.94
Increased toxicity of diphtheria toxin for human lymphoblastoid cells following covalent linkage to anti-(human lymphocyte) globulin or its F(ab')2 fragment. Eur J Biochem (1980) 0.91
New doxorubicin analogs active against doxorubicin-resistant colon tumor xenografts in the nude mouse. Cancer Res (1980) 0.89
Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell (1994) 9.51
A procedure for rapid and sensitive staining of protein fractionated by polyacrylamide gel electrophoresis. Anal Biochem (1967) 7.96
Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition. Proc Natl Acad Sci U S A (1983) 4.56
Protein iodination with solid state lactoperoxidase. Biochemistry (1974) 4.52
Nature and Development of Lactic Dehydrogenases: The two major types of this enzyme form molecular hybrids which change in makeup during development. Science (1962) 3.95
Electrophoretic heterogeneity of polypeptide chains of specific antibodies. Science (1966) 3.88
Enhancement of sheep red blood cell human lymphocyte rosette formation by the sulfhydryl compound 2-amino ethylisothiouronium bromide. Clin Immunol Immunopathol (1975) 3.11
Lactate dehydrogenases: structure and function. Adv Enzymol Relat Areas Mol Biol (1973) 2.58
The comparative enzymology of creatine kinases. I. Isolation and characterization from chicken and rabbit tissues. J Biol Chem (1967) 2.54
Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc Natl Acad Sci U S A (1994) 2.30
Kinetics of Escherichia coli B D-lactate dehydrogenase and evidence for pyruvate-controlled change in conformation. J Biol Chem (1968) 2.27
Unique glycoprotein-proteoglycan complex defined by monoclonal antibody on human melanoma cells. Proc Natl Acad Sci U S A (1982) 2.21
Salt extraction of soluble HL-A antigens. Science (1971) 2.18
METABOLISM IN DIABETIC COMA PRODUCED BY ALLOXAN. Science (1945) 2.15
Separation of 7S gamma-1-globulin, 7S gamma-2-globulin and macroglobulin guinea pig antibodies. Proc Soc Exp Biol Med (1966) 2.08
Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis. Proc Natl Acad Sci U S A (1992) 2.07
Hydrogen evolution by a chloroplast-ferredoxin-hydrogenase system. Proc Natl Acad Sci U S A (1973) 2.02
Detection of ganglioside GD2 in tumor tissues and sera of neuroblastoma patients. Cancer Res (1984) 2.01
Serologic evidence for antigens controlled by the Ir region in mice. J Exp Med (1973) 1.94
Chemical characterization of D-lactate dehydrogenase from Escherichia coli B. J Biol Chem (1968) 1.88
Structure-function relationships in lactate dehydrogenase. Proc Natl Acad Sci U S A (1973) 1.87
Structural studies of murine I-E and human DR antigens. Mol Immunol (1979) 1.79
Transplantation antigens. Adv Immunol (1970) 1.70
Murine Ia and human DR antigens: homology of amino-terminal sequences. Proc Natl Acad Sci U S A (1978) 1.70
Augmentation of antibody dependent cell mediated cytotoxicity following in vivo therapy with recombinant interleukin 2. Cancer Res (1990) 1.69
Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer. Br J Cancer (2011) 1.69
Biologically active catecholamines covalentyly bound to glass beads. Proc Natl Acad Sci U S A (1972) 1.68
Disialoganglioside GD2 on human neuroblastoma cells: target antigen for monoclonal antibody-mediated cytolysis and suppression of tumor growth. Cancer Res (1987) 1.68
Phase I trial of a human-mouse chimeric anti-disialoganglioside monoclonal antibody ch14.18 in patients with refractory neuroblastoma and osteosarcoma. J Clin Oncol (1998) 1.67
Targeted interleukin-2 therapy for spontaneous neuroblastoma metastases to bone marrow. J Natl Cancer Inst (1997) 1.64
Natural killer cell-mediated eradication of neuroblastoma metastases to bone marrow by targeted interleukin-2 therapy. Blood (1998) 1.64
A phase I/IB trial of murine monoclonal anti-GD2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma: a report of the Children's Cancer Group. Cancer (1997) 1.63
Molecular cloning and characterization of a human adenocarcinoma/epithelial cell surface antigen complementary DNA. Cancer Res (1989) 1.62
A phase I study of human/mouse chimeric antiganglioside GD2 antibody ch14.18 in patients with neuroblastoma. Eur J Cancer (1995) 1.59
An acid phosphatase in the plasma membranes of human astrocytoma showing marked specificity toward phosphotyrosine protein. Proc Natl Acad Sci U S A (1982) 1.58
A rapid method for direct HL-A typing of cultured lymphoid cells. J Immunol (1971) 1.55
Antibody-targeted interleukin 2 stimulates T-cell killing of autologous tumor cells. Proc Natl Acad Sci U S A (1992) 1.51
Characterization of Ia antigens in mouse serum. J Immunol (1976) 1.51
Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin alpha v beta 3. J Cell Biol (1996) 1.50
Effect of a chimeric anti-ganglioside GD2 antibody on cell-mediated lysis of human neuroblastoma cells. Cancer Res (1991) 1.48
The activity of the acidic phosphoproteins from the 80 S rat liver ribosome. J Biol Chem (1982) 1.48
Antigens associated with a human lung adenocarcinoma defined by monoclonal antibodies. Cancer Res (1984) 1.48
Functional properties and effect on growth suppression of human neuroblastoma tumors by isotype switch variants of monoclonal antiganglioside GD2 antibody 14.18. Cancer Res (1989) 1.45
An Arg-Gly-Asp-directed receptor on the surface of human melanoma cells exists in an divalent cation-dependent functional complex with the disialoganglioside GD2. J Cell Biol (1987) 1.44
Enhancement of antibody-dependent cytotoxicity with a chimeric anti-GD2 antibody. J Immunol (1990) 1.44
A phase I study of neuroblastoma with the anti-ganglioside GD2 antibody 14.G2a. Cancer Immunol Immunother (1992) 1.44
Enzymatically active conformers of mitochondrial malate dehydrogenase. Proc Natl Acad Sci U S A (1966) 1.43
Production and characterization of monoclonal antibody to a melanoma specific glycoprotein. Hybridoma (1981) 1.42
Reversal of P-glycoprotein-mediated multidrug resistance by a potent cyclopropyldibenzosuberane modulator, LY335979. Cancer Res (1996) 1.39
Localization of the gangliosides GD2 and GD3 in adhesion plaques and on the surface of human melanoma cells. Proc Natl Acad Sci U S A (1984) 1.39
O-acetylation of disialoganglioside GD3 by human melanoma cells creates a unique antigenic determinant. Science (1984) 1.38
Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line. Cancer Res (1994) 1.36
The comparative enzymology of lactic dehydrogenases. 3. Properties of the H4 and M4 enzymes from a number of vertebrates. J Biol Chem (1967) 1.35
Immobilization of hydrogenase on glass beads. Biochem Biophys Res Commun (1976) 1.34
Complete regression of human B-cell lymphoma xenografts in mice treated with recombinant anti-CD22 immunotoxin RFB4(dsFv)-PE38 at doses tolerated by cynomolgus monkeys. Int J Cancer (1999) 1.34
Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2. Cancer Res (1998) 1.33
Cytotoxic activity of disulfide-stabilized recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) toward fresh malignant cells from patients with B-cell leukemias. Clin Cancer Res (2000) 1.33
Isolation and characterization of a mitogen from pokeweek (Phytolacca americana). Proc Natl Acad Sci U S A (1967) 1.32
The comparative enzymology of creatine kinases. II. Physical and chemical properties. J Biol Chem (1967) 1.31
Matrix metalloproteinase-2 activation modulates glioma cell migration. J Cell Sci (1997) 1.31
A monoclonal antibody recognizes an O-acylated sialic acid in a human melanoma-associated ganglioside. J Biol Chem (1984) 1.31
The comparative enzymology of lactic dehydrogenases. IV. Function of sulfhydryl groups in lactic dehydrogenases and the sequence around the essential group. J Biol Chem (1965) 1.30
Purification and properties of two types of diphosphopyridine nucleotide-linked glycerol 3-phosphate dehydrogenases from chicken breast muscle and chicken liver. J Biol Chem (1969) 1.29
Malate dehydrogenases. II. Purification and properties of Bacillus subtilis, Bacillus stearothermophilus, and Escherichia coli malate dehydrogenases. J Biol Chem (1967) 1.28
Proteases and protease inhibitors in tumor progression. Adv Exp Med Biol (1997) 1.27
Association by hydrogen bonding of mononucleotides in aqueous solution. Proc Natl Acad Sci U S A (1972) 1.27
Phase IB trial of chimeric antidisialoganglioside antibody plus interleukin 2 for melanoma patients. Clin Cancer Res (1997) 1.27
KSA antigen Ep-CAM mediates cell-cell adhesion of pancreatic epithelial cells: morphoregulatory roles in pancreatic islet development. J Cell Biol (1998) 1.26
Targeting of lymphotoxin-alpha to the tumor elicits an efficient immune response associated with induction of peripheral lymphoid-like tissue. Immunity (2001) 1.26
Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan. Proc Natl Acad Sci U S A (1996) 1.25
Elimination of established murine colon carcinoma metastases by antibody-interleukin 2 fusion protein therapy. Cancer Res (1997) 1.22
Biosynthetic studies of proteoglycans in human melanoma cells with a monoclonal antibody to a core glycoprotein of chondroitin sulfate proteoglycans. J Biol Chem (1984) 1.22
Correlation of chondroitin sulfate proteoglycan expression on proliferating brain capillary endothelial cells with the malignant phenotype of astroglial cells. Cancer Res (1991) 1.22
Creatine kinase: evidence for a dimeric structure. Biochem Biophys Res Commun (1965) 1.21
Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2. Anticancer Res (1998) 1.21
Variations at the carboxyl-terminal amino acid sequence of rabbit light chains with b4, b5 and b6 allotypic specificities. J Mol Biol (1969) 1.21
Biological and chemical characterization of human histocompatibility antigens. Fed Proc (1971) 1.19
Evaluation of C3 receptors on lymphoid cells with different complement sources. J Immunol (1974) 1.19
Transplantaton antigens. Science (1969) 1.18
A mechanism for neutrophil-mediated lysis of human neuroblastoma cells. Cancer Res (1993) 1.18
T cell-mediated eradication of murine metastatic melanoma induced by targeted interleukin 2 therapy. J Exp Med (1996) 1.17
An autologous oral DNA vaccine protects against murine melanoma. Proc Natl Acad Sci U S A (2000) 1.17
The role of proto-oncogene Fra-1 in remodeling the tumor microenvironment in support of breast tumor cell invasion and progression. Oncogene (2009) 1.17
Reversible inactivation of dehydrogenases. J Biol Chem (1966) 1.16
IFN-gamma-inducible protein-10 is essential for the generation of a protective tumor-specific CD8 T cell response induced by single-chain IL-12 gene therapy. J Immunol (2001) 1.16
The lymphocytotoxic reaction: the mechanism of rabbit complement action. J Immunol (1971) 1.15
Human tumor antigens. Adv Immunol (1987) 1.14
Suppression of spontaneous melanoma metastasis in scid mice with an antibody to the epidermal growth factor receptor. Cancer Res (1991) 1.13
Expression of HL-A antigens in synchronized cultures of human lymphocytes. J Immunol (1972) 1.12
Anti-tumor activity of K1-LysPE38QQR, an immunotoxin targeting mesothelin, a cell-surface antigen overexpressed in ovarian cancer and malignant mesothelioma. J Immunother (2000) 1.11
Nature of multiple molecular forms of enzymes. Ann N Y Acad Sci (1968) 1.11
Eradication of human hepatic and pulmonary melanoma metastases in SCID mice by antibody-interleukin 2 fusion proteins. Proc Natl Acad Sci U S A (1996) 1.11
Highly efficient induction of type C retroviruses by a human tumor in athymic mice. Proc Natl Acad Sci U S A (1980) 1.11
Activation of human effector cells by a tumor reactive recombinant anti-ganglioside GD2 interleukin-2 fusion protein (ch14.18-IL2). Clin Cancer Res (1996) 1.10
The formation of ternary complexes by diphosphopyridine nucleotide-dependent dehydrogenases. Arch Biochem Biophys (1971) 1.10
Purification of porcine thyrocalcitonin. Proc Natl Acad Sci U S A (1967) 1.10
Effect of phagocytosis and Fc receptor occupancy on complement-dependent neutrophil chemotaxis. J Lab Clin Med (1978) 1.10