Published in Nucleic Acids Res on September 25, 1981
Compilation of published signal sequences. Nucleic Acids Res (1984) 11.33
Isolation and characterization of a cDNA encoding a human liver/bone/kidney-type alkaline phosphatase. Proc Natl Acad Sci U S A (1986) 3.62
Determinants for glycophospholipid anchoring of the Saccharomyces cerevisiae GAS1 protein to the plasma membrane. Mol Cell Biol (1991) 2.96
Rapid processing of the carboxyl terminus of a trypanosome variant surface glycoprotein. Proc Natl Acad Sci U S A (1985) 2.67
Posttranslational modification and intracellular transport of a trypanosome variant surface glycoprotein. J Cell Biol (1986) 1.83
Isolation and nucleotide sequence of mouse NCAM cDNA that codes for a Mr 79,000 polypeptide without a membrane-spanning region. EMBO J (1987) 1.83
Characterization of the DNA duplication-transposition that controls the expression of two genes for variant surface glycoproteins in Trypanosoma brucei. Nucleic Acids Res (1982) 1.79
Molecular biology of trypanosome antigenic variation. Microbiol Rev (1985) 1.59
Duplication and transcription of procyclin genes in Trypanosoma brucei. Nucleic Acids Res (1989) 1.52
Carbohydrate is linked through ethanolamine to the C-terminal amino acid of Trypanosoma brucei variant surface glycoprotein. Biochem J (1983) 1.50
Anchoring of membrane proteins via phosphatidylinositol is deficient in two classes of Thy-1 negative mutant lymphoma cells. EMBO J (1986) 1.49
Biosynthesis, membrane association, and release of N-CAM-120, a phosphatidylinositol-linked form of the neural cell adhesion molecule. J Cell Biol (1987) 1.36
Homologous 3'-terminal regions of mRNAs for surface antigens of different antigenic variants of Trypanosoma brucei. Nucleic Acids Res (1981) 1.31
Fusion of sequence elements from non-anchored proteins to generate a fully functional signal for glycophosphatidylinositol membrane anchor attachment. J Cell Biol (1991) 1.19
Intracellular transport of a variant surface glycoprotein in Trypanosoma brucei. J Cell Biol (1988) 1.18
A nonfunctional sequence converted to a signal for glycophosphatidylinositol membrane anchor attachment. J Cell Biol (1991) 1.14
Size fractionation of Trypanosoma brucei DNA: localization of the 177-bp repeat satellite DNA and a variant surface glycoprotein gene in a mini-chromosomal DNA fraction. Nucleic Acids Res (1983) 1.11
Glycosylphosphatidylinositol-dependent secretory transport in Trypanosoma brucei. Biochem J (1998) 1.11
Reverse transcription of trypanosome variable antigen mRNAs initiated by a specific oligonucleotide primer. Proc Natl Acad Sci U S A (1983) 1.10
Expression of bloodstream variant surface glycoproteins in procyclic stage Trypanosoma brucei: role of GPI anchors in secretion. EMBO J (1997) 1.06
Proteins containing an uncleaved signal for glycophosphatidylinositol membrane anchor attachment are retained in a post-ER compartment. J Cell Biol (1992) 1.04
An internally positioned signal can direct attachment of a glycophospholipid membrane anchor. J Cell Biol (1991) 1.01
The secretory pathway of protists: spatial and functional organization and evolution. Microbiol Rev (1996) 0.96
The variable surface glycoproteins of Trypanosoma equiperdum are phosphorylated. EMBO J (1982) 0.95
Transcription of a transposed trypanosome surface antigen gene starts upstream of the transposed segment. EMBO J (1985) 0.90
Life and times: synthesis, trafficking, and evolution of VSG. Trends Parasitol (2014) 0.88
Glycosyl-phosphatidylinositol anchor attachment in a yeast in vitro system. Biochem J (1997) 0.81
Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68
3' non-coding region sequences in eukaryotic messenger RNA. Nature (1976) 39.12
Further procedures for sequence analysis by computer. Nucleic Acids Res (1978) 18.94
The ovalbumin gene-sequence of putative control regions. Nucleic Acids Res (1980) 18.04
Identification, purification and properties of clone-specific glycoprotein antigens constituting the surface coat of Trypanosoma brucei. Parasitology (1975) 7.22
Two mRNAs with different 3' ends encode membrane-bound and secreted forms of immunoglobulin mu chain. Cell (1980) 6.32
Antigenic drift between the haemagglutinin of the Hong Kong influenza strains A/Aichi/2/68 and A/Victoria/3/75. Nature (1980) 5.25
The mechanism of protein secretion across membranes. Nature (1980) 4.72
Evaluation of the "scanning model" for initiation of protein synthesis in eucaryotes. Cell (1980) 3.98
Antigenic variation in trypanosomes. Nature (1978) 3.24
The isolation of plasmids containing DNA complementary to messenger RNA for variant surface glycoproteins of Trypanosoma brucei. Gene (1980) 2.99
N-terminal amino acid sequences of variant-specific surface antigens from Trypanosoma brucei. Nature (1976) 2.64
Novel expression-linked copies of the genes for variant surface antigens in trypanosomes. Nature (1980) 2.51
Antigenic variation in trypanosomes. Proc R Soc Lond B Biol Sci (1978) 2.05
Glycopeptides from variant surface glycoproteins of Trypanosoma Brucei. C-terminal location of antigenically cross-reacting carbohydrate moieties. Mol Biochem Parasitol (1981) 2.00
A variant surface glycoprotein of Trypanosoma brucei synthesized with a C-terminal hydrophobic 'tail' absent from purified glycoprotein. Nature (1980) 1.65
Selective cleavage of variant surface glycoproteins from Trypanosoma brucei. Biochem J (1979) 1.23
An introduction to antigenic variation in trypanosomes. Am J Trop Med Hyg (1980) 0.98
The gel electrophoresis of DNA. Biochim Biophys Acta (1972) 11.85
A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei. Mol Biochem Parasitol (1999) 11.77
A freeze-squeeze method for recovering long DNA from agarose gels. Anal Biochem (1975) 11.28
Identification, purification and properties of clone-specific glycoprotein antigens constituting the surface coat of Trypanosoma brucei. Parasitology (1975) 7.22
Direct and sensitive detection of a pathogenic protozoan, Toxoplasma gondii, by polymerase chain reaction. J Clin Microbiol (1989) 5.85
Discontinuous transcription and antigenic variation in trypanosomes. Annu Rev Biochem (1986) 5.60
Evidence for trans splicing in trypanosomes. Cell (1986) 5.58
Virulent strains of Toxoplasma gondii comprise a single clonal lineage. Nature (1992) 4.92
Renaturation of mitochondrial DNA. Biochim Biophys Acta (1966) 4.79
Mitochondrial DNA from sheep heart. Proc Natl Acad Sci U S A (1966) 4.65
Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum. Proc Natl Acad Sci U S A (1988) 4.58
Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue. Nature (2006) 4.50
Mitochondrial nucleic acids. Annu Rev Biochem (1972) 4.25
Polymorphic secreted kinases are key virulence factors in toxoplasmosis. Science (2006) 4.23
Programmed gene rearrangements altering gene expression. Science (1987) 4.12
Antigenic variation in Trypanosoma brucei analyzed by electrophoretic separation of chromosome-sized DNA molecules. Cell (1984) 4.03
Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii. J Immunol (1988) 3.98
Tumour predisposition in mice heterozygous for a targeted mutation in Nf1. Nat Genet (1994) 3.97
The mitochondrial genome of yeast. Cell (1978) 3.84
Molecular basis for trypanosome antigenic variation. Cell (1982) 3.80
Mitochondrial DNA. V. A 25 micron closed circular duplex DNA molecule in wild-type yeast mitochondria. Stucture and genetic complexity. Biochim Biophys Acta (1970) 3.67
Activation of trypanosome surface glycoprotein genes involves a duplication-transposition leading to an altered 3' end. Cell (1981) 3.65
Glycosyl-sn-1,2-dimyristylphosphatidylinositol is covalently linked to Trypanosoma brucei variant surface glycoprotein. J Biol Chem (1985) 3.64
Transient transfection and expression in the obligate intracellular parasite Toxoplasma gondii. Science (1993) 3.36
Neuronal pp60c-src contains a six-amino acid insertion relative to its non-neuronal counterpart. Science (1987) 3.35
Three small RNAs within the 10 kb trypanosome rRNA transcription unit are analogous to domain VII of other eukaryotic 28S rRNAs. Nucleic Acids Res (1986) 3.30
Structure of the growing telomeres of Trypanosomes. Cell (1984) 3.24
Success and virulence in Toxoplasma as the result of sexual recombination between two distinct ancestries. Science (2001) 3.21
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins. Proc Natl Acad Sci U S A (1997) 3.20
Growth of chromosome ends in multiplying trypanosomes. Nature (1983) 3.16
Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. J Clin Invest (1995) 3.13
Eukaryotic protein modification and membrane attachment via phosphatidylinositol. Cell (1987) 3.08
Gel electrophoresis of RNA under denaturing conditions. Biochim Biophys Acta (1973) 3.05
The isolation of plasmids containing DNA complementary to messenger RNA for variant surface glycoproteins of Trypanosoma brucei. Gene (1980) 2.99
Gene replacement in Toxoplasma gondii with chloramphenicol acetyltransferase as selectable marker. Science (1993) 2.98
Inactivation of transcription by UV irradiation of T. brucei provides evidence for a multicistronic transcription unit including a VSG gene. Cell (1987) 2.93
Targeted insertion of the neomycin phosphotransferase gene into the tubulin gene cluster of Trypanosoma brucei. Nature (1990) 2.91
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine. Proc Natl Acad Sci U S A (1997) 2.91
MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine. Cell (1996) 2.87
RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes. Nucleic Acids Res (1982) 2.87
Unusual abundance of atypical strains associated with human ocular toxoplasmosis. J Infect Dis (2001) 2.86
Alternative 5' exons in c-abl mRNA. Cell (1986) 2.85
Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes. Nature (1984) 2.85
Lytic cycle of Toxoplasma gondii. Microbiol Mol Biol Rev (2000) 2.84
Nucleotide sequence of the mitochondrial structural gene for subunit 9 of yeast ATPase complex. Proc Natl Acad Sci U S A (1979) 2.83
Genomic environment of the expression-linked extra copies of genes for surface antigens of Trypanosoma brucei resembles the end of a chromosome. Nature (1982) 2.75
Alpha-amanitin-insensitive transcription of variant surface glycoprotein genes provides further evidence for discontinuous transcription in trypanosomes. Nucleic Acids Res (1984) 2.74
Tandem repetition of the 5' mini-exon of variant surface glycoprotein genes: a multiple promoter for VSG gene transcription? Cell (1983) 2.67
Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res (1997) 2.67
N-terminal amino acid sequences of variant-specific surface antigens from Trypanosoma brucei. Nature (1976) 2.64
The anatomy and transcription of a telomeric expression site for variant-specific surface antigens in T. brucei. Cell (1987) 2.63
Polycistronic transcripts in trypanosomes and their accumulation during heat shock: evidence for a precursor role in mRNA synthesis. Mol Cell Biol (1988) 2.63
Overexpression and amplification of five genes in a multidrug-resistant Chinese hamster ovary cell line. Mol Cell Biol (1986) 2.59
Transcripts coding for variant surface glycoproteins of Trypanosoma brucei have a short, identical exon at their 5' end. Gene (1982) 2.58
Discontinuous synthesis of mRNA in trypanosomes. EMBO J (1984) 2.57
Chromosome rearrangements in Trypanosoma brucei. Cell (1984) 2.56
Protective monoclonal antibodies recognising stage-specific merozoite antigens of a rodent malaria parasite. Nature (1980) 2.55
Biosynthesis of Trypanosoma brucei variant surface glycoproteins. N-glycosylation and addition of a phosphatidylinositol membrane anchor. J Biol Chem (1986) 2.54
An insert in the single gene for the large ribosomal RNA in yeast mitochondrial DNA. Nature (1978) 2.53
Expression of a bacterial gene in a trypanosomatid protozoan. Science (1989) 2.52
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport. Proc Natl Acad Sci U S A (1994) 2.52
Novel expression-linked copies of the genes for variant surface antigens in trypanosomes. Nature (1980) 2.51
Hypermodified bases in DNA. FASEB J (1995) 2.49
Localization of nine glycolytic enzymes in a microbody-like organelle in Trypanosoma brucei: the glycosome. FEBS Lett (1977) 2.44
Molecular cloning and cellular localization of a BiP homologue in Trypanosoma brucei. Divergent ER retention signals in a lower eukaryote. J Cell Sci (1993) 2.44
The organization of ribosomal RNA genes in the mitochondrial DNA of Tetrahymena pyriformis strain ST. Biochim Biophys Acta (1978) 2.42
The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei. EMBO J (1990) 2.41
Comparison of the genes coding for the common 5' terminal sequence of messenger RNAs in three trypanosome species. Nucleic Acids Res (1984) 2.40
Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. Science (1996) 2.35
Rescue of a Drosophila NF1 mutant phenotype by protein kinase A. Science (1997) 2.30
Kinetoplast DNA. Plasmid (1979) 2.20
Rapid isolation of DNA from trypanosomatid protozoa using a simple 'mini-prep' procedure. Mol Biochem Parasitol (1993) 2.19
An analysis of cosmid clones of nuclear DNA from Trypanosoma brucei shows that the genes for variant surface glycoproteins are clustered in the genome. Nucleic Acids Res (1982) 2.16
Gene discovery by EST sequencing in Toxoplasma gondii reveals sequences restricted to the Apicomplexa. Genome Res (1998) 2.14
Many trypanosome messenger RNAs share a common 5' terminal sequence. Nucleic Acids Res (1984) 2.11
Cultivation of Trypanosoma brucei sspp. in semi-defined and defined media. Parasitology (1973) 2.10
Trypanosoma brucei variant surface glycoprotein has a sn-1,2-dimyristyl glycerol membrane anchor at its COOH terminus. J Biol Chem (1985) 2.10
How proteins get into microbodies (peroxisomes, glyoxysomes, glycosomes). Biochim Biophys Acta (1986) 2.08
Myristylation of the membrane form of a Trypanosoma brucei variant surface glycoprotein. J Biol Chem (1984) 2.07
Microarray analysis reveals previously unknown changes in Toxoplasma gondii-infected human cells. J Biol Chem (2001) 2.06
Isolation and characterization of kinetoplast DNA from bloodstream form of Trypanosoma brucei. J Cell Biol (1978) 2.06
Antigenic variation in trypanosomes. Proc R Soc Lond B Biol Sci (1978) 2.05
Toxoplasma gondii homologue of plasmodium apical membrane antigen 1 is involved in invasion of host cells. Infect Immun (2000) 2.03
Generation of a restriction fragment length polymorphism linkage map for Toxoplasma gondii. Genetics (1992) 2.01
Glycopeptides from variant surface glycoproteins of Trypanosoma Brucei. C-terminal location of antigenically cross-reacting carbohydrate moieties. Mol Biochem Parasitol (1981) 2.00
An unusually compact ribosomal DNA repeat in the protozoan Giardia lamblia. Nucleic Acids Res (1987) 2.00
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein. Proc Natl Acad Sci U S A (1995) 2.00
beta-D-glucosyl-hydroxymethyluracil: a novel modified base present in the DNA of the parasitic protozoan T. brucei. Cell (1993) 2.00
Mitochondrial DNA: physicochemical properties, replication, and genetic function. Int Rev Cytol (1969) 1.99
The transposition unit of variant surface glycoprotein gene 118 of Trypanosoma brucei. Presence of repeated elements at its border and absence of promoter-associated sequences. J Mol Biol (1983) 1.98
Acylation of a Plasmodium falciparum merozoite surface antigen via sn-1,2-diacyl glycerol. J Biol Chem (1985) 1.98