Published in Biochemistry on May 25, 1982
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Changes in cell shape correlate with collagenase gene expression in rabbit synovial fibroblasts. J Cell Biol (1984) 1.67
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Endogenous activiation of latent collagenase by rheumatoid synovial cells. Evidence for a role of plasminogen activator. N Engl J Med (1977) 3.81
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Post-translational cleavage of presecretory proteins with an extract of rough microsomes from dog pancreas containing signal peptidase activity. Proc Natl Acad Sci U S A (1977) 3.54
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Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins. Science (1999) 3.22
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Isolation of a cDNA for HSF2: evidence for two heat shock factor genes in humans. Proc Natl Acad Sci U S A (1991) 2.89
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Collagenases in human synovial fluid. J Clin Invest (1969) 2.52
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Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family. J Biol Chem (1999) 2.33
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An endopeptidase from rheumatoid synovial tissue culture. Biochim Biophys Acta (1972) 2.25
Post-translational processing of full-length presecretory proteins with canine pancreatic signal peptidase. Ann N Y Acad Sci (1980) 2.23
Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1. Nature (1997) 2.17
Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts. Purification and activation of the precursor and enzymic properties. Eur J Biochem (1990) 2.13
Secretion requires a cytoplasmically disposed sulphydryl of the RER membrane. Nature (1980) 2.10
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Mechanisms of activation of tissue procollagenase by matrix metalloproteinase 3 (stromelysin). Biochemistry (1990) 2.06
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The amount and proteolytic content of vesicles shed by human cancer cell lines correlates with their in vitro invasiveness. Anticancer Res (1998) 1.94
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Using inhibitors of metalloproteinases to treat arthritis. Easier said than done? Arthritis Rheum (1994) 1.93
Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol (1998) 1.90
Particulate matter and heart rate variability among elderly retirees: the Baltimore 1998 PM study. J Expo Anal Environ Epidemiol (2001) 1.85
Regulation of matrix metalloproteinases (MMP-2, -3, -9, and -13) by interleukin-1 and interleukin-6 in mouse calvaria: association of MMP induction with bone resorption. Endocrinology (1998) 1.75
Localization of matrix metalloproteinase 3 (stromelysin) in osteoarthritic cartilage and synovium. Lab Invest (1992) 1.74
Nuclear factor kappaB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1beta-stimulated synovial fibroblasts. Arthritis Rheum (1998) 1.73
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Cleavage of Type II and III collagens with mammalian collagenase: site of cleavage and primary structure at the NH2-terminal portion of the smaller fragment released from both collagens. Biochemistry (1976) 1.72
IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways. Nucleic Acids Res (2001) 1.71
Immunolocalization of matrix metalloproteinase 3 (stromelysin) in rheumatoid synovioblasts (B cells): correlation with rheumatoid arthritis. Ann Rheum Dis (1989) 1.71
Degradation of interleukin 1beta by matrix metalloproteinases. J Biol Chem (1996) 1.69
Evaluation of injuries in youth soccer. Am J Sports Med (1980) 1.69
Purification and characterization of a collagenase extracted from rabbit tumours. Biochem J (1975) 1.69
Studies on glycopeptides released by trypsin from intact human erythrocytes. Biochemistry (1967) 1.67
Effect of penicillamine on human collagen and its possible application to treatment of scleroderma. Lancet (1966) 1.66
Rat collagenase. Cloning, amino acid sequence comparison, and parathyroid hormone regulation in osteoblastic cells. J Biol Chem (1990) 1.63
IMP dehydrogenase, an enzyme linked with proliferation and malignancy. Nature (1975) 1.62
Frequent somatic mutations of the APC gene in human pancreatic cancer. Cancer Res (1992) 1.55
The complete primary structure of human matrix metalloproteinase-3. Identity with stromelysin. J Biol Chem (1988) 1.54
Recent insights into the pathogenesis of the proliferative lesion in rheumatoid arthritis. Arthritis Rheum (1976) 1.54
Human plasma kallikrein. A rapid purification method with high yield. Biochem J (1981) 1.53
A gene for rabbit synovial cell collagenase: member of a family of metalloproteinases that degrade the connective tissue matrix. Biochemistry (1987) 1.52
Nor-binaltorphimine: a potent and selective kappa-opioid receptor antagonist with long-lasting activity in vivo. Arch Int Pharmacodyn Ther (1992) 1.51
Collagenase production by rheumatoid synovial cells: morphological and immunohistochemical studies of the dendritic cell. Ann Rheum Dis (1979) 1.50
Detection of 12 germ-line mutations in the adenomatous polyposis coli gene by polymerase chain reaction. Gastroenterology (1993) 1.49
Regulation of the mammalian collagenases. Coll Relat Res (1984) 1.49
Collagenase immunolocalization in cultures of rheumatoid synovial cells. Science (1978) 1.49
The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer. Cancer Res (1992) 1.47
Urokinase plasminogen activator and gelatinases are associated with membrane vesicles shed by human HT1080 fibrosarcoma cells. J Biol Chem (1997) 1.45
Native cross-links in collagen fibrils induce resistance to human synovial collagenase. Biochem J (1979) 1.45
Biochemical characterization of a factor released by macrophages. Cell Immunol (1975) 1.44
Effects of colchicine on collagenase in cultures of rheumatoid synovium. Arthritis Rheum (1972) 1.43
Structural properties of matrix metalloproteinases. Cell Mol Life Sci (1999) 1.43
The isolation of ecdysterone inducible genes by hybridization subtraction chromatography. Nucleic Acids Res (1981) 1.43
Collagenases (second of three parts). N Engl J Med (1974) 1.42
Synovial procollagenase activation by human mast cell tryptase dependence upon matrix metalloproteinase 3 activation. J Clin Invest (1989) 1.42
A quantitative test for copper using bicinchoninic acid. Anal Biochem (1995) 1.42
Anticancer activity of the structurally novel antibiotic Cl-920 and its analogues. Cancer Res (1984) 1.42
Purification of an endogenous activator of procollagenase from rabbit synovial fibroblast culture medium. J Biol Chem (1983) 1.42
Steps involved in activation of the pro-matrix metalloproteinase 9 (progelatinase B)-tissue inhibitor of metalloproteinases-1 complex by 4-aminophenylmercuric acetate and proteinases. J Biol Chem (1995) 1.42
Synovial collagenase: its presence in culture from joint disease of diverse etiology. Arthritis Rheum (1969) 1.40
Cytochalasin B increases collagenase production by cells in vitro. Nature (1975) 1.40
Inactivation of tissue inhibitor of metalloproteinases by neutrophil elastase and other serine proteinases. FEBS Lett (1988) 1.39
Regulating expression of the gene for matrix metalloproteinase-1 (collagenase): mechanisms that control enzyme activity, transcription, and mRNA stability. Crit Rev Eukaryot Gene Expr (1996) 1.38
Inhibition of matrix metalloproteinases prevents allergen-induced airway inflammation in a murine model of asthma. J Immunol (1999) 1.38
The liberally educated and the physician. Pharos Alpha Omega Alpha Honor Med Soc (1999) 1.38
Diagnosis: degrees of difficulty and degrees of urgency. Pharos Alpha Omega Alpha Honor Med Soc (1997) 1.38
Elevated levels of collagenase and prostaglandin E2 from synovium associated with erosion of cartilage and bone in a patient with chronic Lyme arthritis. Arthritis Rheum (1980) 1.38
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A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis. Oncogene (2009) 1.35
Hydrolysis of triple-helical collagen peptide models by matrix metalloproteinases. J Biol Chem (2000) 1.35
Biochemical and antitumor activity of tiazofurin and its selenium analog (2-beta-D-ribofuranosyl-4-selenazolecarboxamide). Biochem Pharmacol (1985) 1.34
The influence of temperature and fibril stability on degradation of cartilage collagen by rheumatoid synovial collagenase. N Engl J Med (1974) 1.34
Selective localization of matrix metalloproteinase 9, beta1 integrins, and human lymphocyte antigen class I molecules on membrane vesicles shed by 8701-BC breast carcinoma cells. Cancer Res (1998) 1.33
Increased proliferation of human synovial fibroblasts treated with recombinant immune interferon. J Immunol (1985) 1.33
Identification of the (183)RWTNNFREY(191) region as a critical segment of matrix metalloproteinase 1 for the expression of collagenolytic activity. J Biol Chem (2000) 1.32
Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures. J Biol Chem (1994) 1.32
Inhibitor of human collagenase from cultures of human tendon. J Biol Chem (1979) 1.32
The AP-1 sequence is necessary but not sufficient for phorbol induction of collagenase in fibroblasts. Biochemistry (1991) 1.31
Enzymic and Photosynthetic Characteristics of Reciprocal F(1) Hybrids of Flaveria pringlei (C(3)) and Flaveria brownii (C(4)-Like Species). Plant Physiol (1988) 1.31
The precursor of a metalloendopeptidase from human rheumatoid synovial fibroblasts. Purification and mechanisms of activation by endopeptidases and 4-aminophenylmercuric acetate. Biochem J (1988) 1.30