Published in Biochemistry on April 26, 1983
Compilation of published signal sequences. Nucleic Acids Res (1984) 11.33
The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment. EMBO J (1989) 4.49
The gene structure of human anti-haemophilic factor IX. EMBO J (1984) 4.09
Cloning and characterization of two cDNAs coding for human von Willebrand factor. Proc Natl Acad Sci U S A (1985) 3.41
Direct detection of point mutations by mismatch analysis: application to haemophilia B. Nucleic Acids Res (1989) 2.64
The nucleotide sequence of the gene for human protein C. Proc Natl Acad Sci U S A (1985) 2.24
The human urokinase-plasminogen activator gene and its promoter. Nucleic Acids Res (1985) 2.14
Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones. EMBO J (1986) 2.10
Characterization of an almost full-length cDNA coding for human blood coagulation factor X. Proc Natl Acad Sci U S A (1985) 2.08
Characterization of a cDNA coding for human factor VII. Proc Natl Acad Sci U S A (1986) 1.89
Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA. Proc Natl Acad Sci U S A (1987) 1.71
Nucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulation. Proc Natl Acad Sci U S A (1987) 1.71
Characterization of the gene for the a subunit of human factor XIII (plasma transglutaminase), a blood coagulation factor. Proc Natl Acad Sci U S A (1988) 1.64
Integration site preferences of the Alu family and similar repetitive DNA sequences. Nucleic Acids Res (1985) 1.50
Gamma-carboxyglutamate-containing proteins and the vitamin K-dependent carboxylase. Biochem J (1990) 1.45
Characterization of a cDNA coding for human protein C. Proc Natl Acad Sci U S A (1984) 1.45
Molecular cloning of matrix Gla protein: implications for substrate recognition by the vitamin K-dependent gamma-carboxylase. Proc Natl Acad Sci U S A (1987) 1.43
Characterization of a cDNA coding for human factor X. Proc Natl Acad Sci U S A (1984) 1.36
Cloning of a cDNA coding for human factor V, a blood coagulation factor homologous to factor VIII and ceruloplasmin. Proc Natl Acad Sci U S A (1986) 1.22
Molecular mapping of the heparin-binding exosite of thrombin. Proc Natl Acad Sci U S A (1994) 1.22
Blood coagulation factor X mRNA encodes a single polypeptide chain containing a prepro leader sequence. Nucleic Acids Res (1984) 1.20
Identification of a thrombin sequence with growth factor activity on macrophages. Proc Natl Acad Sci U S A (1986) 1.12
The structure and evolution of a 461 amino acid human protein C precursor and its messenger RNA, based upon the DNA sequence of cloned human liver cDNAs. Nucleic Acids Res (1985) 1.09
Characterization of the osmotic response element of the human aldose reductase gene promoter. Proc Natl Acad Sci U S A (1996) 1.08
A factor IX mutation, verified by direct genomic sequencing, causes haemophilia B by a novel mechanism. EMBO J (1988) 1.06
A novel one-step purification of human alpha-thrombin after direct activation of crude prothrombin enriched from plasma. Biochem J (1991) 0.97
Vitamin K-dependent carboxylase: affinity purification from bovine liver by using a synthetic propeptide containing the gamma-carboxylation recognition site. Proc Natl Acad Sci U S A (1989) 0.94
Partial characterization of vertebrate prothrombin cDNAs: amplification and sequence analysis of the B chain of thrombin from nine different species. Proc Natl Acad Sci U S A (1992) 0.93
Transcriptional analysis of the mts1 gene with specific reference to 5' flanking sequences. Proc Natl Acad Sci U S A (1992) 0.86
Meizothrombin is an unexpectedly zymogen-like variant of thrombin. J Biol Chem (2012) 0.86
Eisenia fetida protease-III-1 functions in both fibrinolysis and fibrogenesis. J Biomed Biotechnol (2007) 0.85
Cloning and characterization of human liver cDNA encoding a protein S precursor. Proc Natl Acad Sci U S A (1987) 0.85
Models of the serine protease domain of the human antithrombotic plasma factor activated protein C and its zymogen. Protein Sci (1994) 0.84
Molecular cloning and sequence analysis of the cDNA for ancrod, a thrombin-like enzyme from the venom of Calloselasma rhodostoma. Biochem J (1993) 0.82
Vitamin K-dependent carboxylase: possible role of the substrate "propeptide" as an intracellular recognition site. Proc Natl Acad Sci U S A (1987) 0.82
DNA sequence analysis: a procedure to find homologies among many sequences. Nucleic Acids Res (1986) 0.78
Catalytically competent human and bovine zeta-thrombin and chimeras generated from unfolded polypeptide chains. Protein Sci (1992) 0.76
Molecular and genetic analysis of a compound heterozygote for dysprothrombinemia of prothrombin Tokushima and hypoprothrombinemia. Am J Hum Genet (1992) 0.75
RFLP for the human prothrombin (F2) gene. Nucleic Acids Res (1990) 0.75
Nucleotide sequence of the gene for human factor IX (antihemophilic factor B). Biochemistry (1985) 11.80
Complete sequence of the cDNA for human alpha 1-antitrypsin and the gene for the S variant. Biochemistry (1984) 3.75
Cloning and characterization of human protease-activated receptor 4. Proc Natl Acad Sci U S A (1998) 3.50
Cloning and characterization of two cDNAs coding for human von Willebrand factor. Proc Natl Acad Sci U S A (1985) 3.41
The human tissue plasminogen activator gene. J Biol Chem (1986) 3.35
Isolation and characterization of a cDNA coding for human factor IX. Proc Natl Acad Sci U S A (1982) 3.14
Anticoagulant properties of bovine plasma protein C following activation by thrombin. Biochemistry (1977) 2.96
Preparation and properties of bovine factor VIII (antihemophilic factor). Biochemistry (1980) 2.89
A comparison of human prothrombin, factor IX (Christmas factor), factor X (Stuart factor), and protein S. Biochemistry (1977) 2.77
Isolation and characterization of human Factor VIII (antihemophilic factor). J Biol Chem (1973) 2.46
The nucleotide sequence of the gene for human protein C. Proc Natl Acad Sci U S A (1985) 2.24
Human genes encoding prothrombin and ceruloplasmin map to 11p11-q12 and 3q21-24, respectively. Somat Cell Mol Genet (1987) 2.21
The role of serine proteases in the blood coagulation cascade. Adv Enzymol Relat Areas Mol Biol (1979) 2.21
Proteolytic activation of protein C from bovine plasma. Biochemistry (1976) 2.12
Characterization of an almost full-length cDNA coding for human blood coagulation factor X. Proc Natl Acad Sci U S A (1985) 2.08
Isolation and characterization of bovine factor IX (Christmas factor). Biochemistry (1973) 2.04
Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders. Blood (1988) 2.01
Aceruloplasminemia: molecular characterization of this disorder of iron metabolism. Proc Natl Acad Sci U S A (1995) 2.01
Structure of the C2 domain of human factor VIII at 1.5 A resolution. Nature (1999) 1.97
Sequence of the cDNA and gene for angiogenin, a human angiogenesis factor. Biochemistry (1985) 1.94
Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation. Proc Natl Acad Sci U S A (1996) 1.93
Nucleotide sequence of the gene for human prothrombin. Biochemistry (1987) 1.92
Cloning and sequence of cDNA coding for alpha 1-antitrypsin. Proc Natl Acad Sci U S A (1981) 1.91
A novel trypsin-like serine protease (hepsin) with a putative transmembrane domain expressed by human liver and hepatoma cells. Biochemistry (1988) 1.89
Nucleotide sequence of the gene for the gamma chain of human fibrinogen. Biochemistry (1985) 1.88
The mechanism of activation of bovine factor IX (Christmas factor) by bovine factor XIa (activated plasma thromboplastin antecedent). Biochemistry (1974) 1.86
The primary structure of human serum transferrin. The structures of seven cyanogen bromide fragments and the assembly of the complete structure. J Biol Chem (1983) 1.83
Activation of human factor IX (Christmas factor). J Clin Invest (1978) 1.82
Role of fibrinogen alpha and gamma chain sites in platelet aggregation. Proc Natl Acad Sci U S A (1992) 1.81
Comparison of amino acid sequence of bovine coagulation Factor IX (Christmas Factor) with that of other vitamin K-dependent plasma proteins. Proc Natl Acad Sci U S A (1979) 1.77
Bovine factors X 1 and X 2 (Stuart factor). Isolation and characterization. Biochemistry (1972) 1.73
Regulation of protein synthesis in mitogen-activated bovine lymphocytes. Analysis of actin-specific and total mRNA accumulation and utilization. J Biol Chem (1983) 1.73
Characterization of protein S, a gamma-carboxyglutamic acid containing protein from bovine and human plasma. Biochemistry (1979) 1.73
Effects of cations on DNA-dependent RNA polymerase. Proc Natl Acad Sci U S A (1967) 1.73
The alpha and beta chains of human platelet glycoprotein Ib are both transmembrane proteins containing a leucine-rich amino acid sequence. Proc Natl Acad Sci U S A (1988) 1.70
Sequence homology and structural comparison between the chromosomal human alpha 1-antitrypsin and chicken ovalbumin genes. Nature (1982) 1.70
Polysome immunoprecipitation of phenylalanine hydroxylase mRNA from rat liver and cloning of its cDNA. Proc Natl Acad Sci U S A (1982) 1.69
gamma and gamma' chains of human fibrinogen are produced by alternative mRNA processing. Biochemistry (1984) 1.67
Basic mechanisms in blood coagulation. Annu Rev Biochem (1975) 1.66
The isolation nd characterization of bovine factor VIII (antihemophilic factor). J Biol Chem (1972) 1.66
Characterization of the gene for the a subunit of human factor XIII (plasma transglutaminase), a blood coagulation factor. Proc Natl Acad Sci U S A (1988) 1.64
Organization of the gene for human factor XI. Biochemistry (1987) 1.62
Gene for human factor X: a blood coagulation factor whose gene organization is essentially identical with that of factor IX and protein C. Biochemistry (1986) 1.62
Crystal structure of a 30 kDa C-terminal fragment from the gamma chain of human fibrinogen. Structure (1997) 1.60
Factor XI deficiency in Ashkenazi Jews in Israel. N Engl J Med (1991) 1.56
Amino acid sequence of human histidine-rich glycoprotein derived from the nucleotide sequence of its cDNA. Biochemistry (1986) 1.52
Amino acid sequence of human factor XI, a blood coagulation factor with four tandem repeats that are highly homologous with plasma prekallikrein. Biochemistry (1986) 1.50
Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor. Biochemistry (1991) 1.49
Localization of the gene encoding human factor V to chromosome 1q21-25. Genomics (1988) 1.46
Bovine factor X 1 (Stuart factor). Mechanism of activation by protein from Russell's viper venom. Biochemistry (1972) 1.46
Characterization of a cDNA coding for human protein C. Proc Natl Acad Sci U S A (1984) 1.45
Cloning and sequencing of liver cDNA coding for bovine protein C. Proc Natl Acad Sci U S A (1984) 1.45
Primary structure of the catalytic subunit of calf thymus DNA polymerase delta: sequence similarities with other DNA polymerases. Biochemistry (1991) 1.44
Structure of transglutaminases. J Biol Chem (1990) 1.43
Ron-mediated cytoplasmic signaling is dispensable for viability but is required to limit inflammatory responses. J Clin Invest (2001) 1.42
Activation of bovine factor IX (Christmas factor) by factor XIa (activated plasma thromboplastin antecedent) and a protease from Russell's viper venom. J Biol Chem (1978) 1.41
Amino acid sequence of the b subunit of human factor XIII, a protein composed of ten repetitive segments. Biochemistry (1986) 1.40
Activation of human factor X (Stuart factor) by a protease from Russell's viper venom. Biochemistry (1977) 1.39
Characterization of a cDNA coding for human factor X. Proc Natl Acad Sci U S A (1984) 1.36
Factor X activating enzyme from Russell's viper venom: isolation and characterization. Biochemistry (1976) 1.35
Prothrombin deficiency results in embryonic and neonatal lethality in mice. Proc Natl Acad Sci U S A (1998) 1.32
Amino acid sequence of the a subunit of human factor XIII. Biochemistry (1986) 1.32
Ligand-induced conformational change in transferrins: crystal structure of the open form of the N-terminal half-molecule of human transferrin. Biochemistry (1998) 1.31
Nucleotide sequence of the cDNA coding for human complement C1r. Biochemistry (1986) 1.29
Cloning and analysis of a cDNA coding for bovine prothrombin. Proc Natl Acad Sci U S A (1980) 1.28
Characterization of human blood coagulation factor XII cDNA. Prediction of the primary structure of factor XII and the tertiary structure of beta-factor XIIa. J Biol Chem (1985) 1.28
Expression of the amino-terminal half-molecule of human serum transferrin in cultured cells and characterization of the recombinant protein. Biochemistry (1990) 1.28
Characterization of human, bovine, and horse antithrombin III. Biochemistry (1976) 1.28
The mechanism of activation of bovine factor X (Stuart factor) by intrinsic and extrinsic pathways. Biochemistry (1974) 1.28
Dual role of Lys206-Lys296 interaction in human transferrin N-lobe: iron-release trigger and anion-binding site. Biochemistry (1999) 1.27
Molecular cloning of human ABPL, an actin-binding protein homologue. Biochem Biophys Res Commun (1998) 1.26
The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro. Proc Natl Acad Sci U S A (1997) 1.26
Transmutation of a heme protein. Proc Natl Acad Sci U S A (1993) 1.25
Location of the disulfide bonds in human coagulation factor XI: the presence of tandem apple domains. Biochemistry (1991) 1.24
A comparison of bovine prothrombin, factor IX (Christmas factor), and factor X (Stuart factor). Proc Natl Acad Sci U S A (1974) 1.24
Characterization of a complementary deoxyribonucleic acid coding for the alpha chain of human fibrinogen. Biochemistry (1983) 1.23
Cloning of a cDNA coding for human factor V, a blood coagulation factor homologous to factor VIII and ceruloplasmin. Proc Natl Acad Sci U S A (1986) 1.22
Nucleotide sequence of the gene for the b subunit of human factor XIII. Biochemistry (1990) 1.21
Activation of human factor XI (plasma thromboplastin antecedent) by factor XIIa (activated Hageman factor). Biochemistry (1977) 1.21
Characterization of a complementary deoxyribonucleic acid coding for the gamma chain of human fibrinogen. Biochemistry (1983) 1.20
Blood coagulation factor X mRNA encodes a single polypeptide chain containing a prepro leader sequence. Nucleic Acids Res (1984) 1.20
Activation of bovine factor VII (proconvertin) by factor XIIa (activated Hageman factor). Biochemistry (1977) 1.20
Characterization of complementary deoxyribonucleic acid and genomic deoxyribonucleic acid for the beta chain of human fibrinogen. Biochemistry (1983) 1.20
Characterization of bovine prothrombin mRNA and its translation product. Biochemistry (1984) 1.19
Human plasma prekallikrein, a zymogen to a serine protease that contains four tandem repeats. Biochemistry (1986) 1.19
Characterization of a cDNA clone coding for the beta chain of bovine fibrinogen. Proc Natl Acad Sci U S A (1981) 1.19
Bovine factor X 1a (activated Stuart factor). Evidence of homology with mammalian serine proteases. Biochemistry (1972) 1.19
Amino acid sequence of human protein Z, a vitamin K-dependent plasma glycoprotein. Biochem Biophys Res Commun (1990) 1.18
Propeptide of human protein C is necessary for gamma-carboxylation. Biochemistry (1987) 1.18
Inhibition of bovine factor IXa and factor Xabeta by antithrombin III. Biochemistry (1976) 1.16
A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha. Blood (1998) 1.16
Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene. Proc Natl Acad Sci U S A (1991) 1.15
Point mutations and overexpression of Ron induce transformation, tumor formation, and metastasis. Oncogene (2001) 1.14
Characterization of a complementary deoxyribonucleic acid coding for human and bovine plasminogen. Biochemistry (1984) 1.13