Published in J Biol Chem on January 25, 1984
The aryl hydrocarbon receptor complex and the control of gene expression. Crit Rev Eukaryot Gene Expr (2008) 3.06
Characterization of xenobiotic responsive elements upstream from the drug-metabolizing cytochrome P-450c gene: a similarity to glucocorticoid regulatory elements. Nucleic Acids Res (1987) 1.96
The specific DNA binding activity of the dioxin receptor is modulated by the 90 kd heat shock protein. EMBO J (1990) 1.70
Glutathione S-transferase Ya subunit gene: identification of regulatory elements required for basal level and inducible expression. Proc Natl Acad Sci U S A (1988) 1.69
Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer. Proc Natl Acad Sci U S A (1988) 1.50
Control of cytochrome P1-450 gene expression: analysis of a dioxin-responsive enhancer system. Proc Natl Acad Sci U S A (1986) 1.41
The Ah receptor and the mechanism of dioxin toxicity. Biochem J (1991) 1.22
Placental markers of human exposure to polychlorinated biphenyls and polychlorinated dibenzofurans. Environ Health Perspect (1987) 1.14
Induction of the Cyp1a-1 dioxin-responsive enhancer in transgenic mice. Nucleic Acids Res (1991) 1.06
Multifunctional receptor model for dioxin and related compound toxic action: possible thyroid hormone-responsive effector-linked site. Environ Health Perspect (1989) 1.01
Analysis of the complex relationship between nuclear export and aryl hydrocarbon receptor-mediated gene regulation. Mol Cell Biol (2000) 0.96
Multiple DNA-binding factors interact with overlapping specificities at the aryl hydrocarbon response element of the cytochrome P450IA1 gene. Mol Cell Biol (1990) 0.92
Mechanism of action of toxic halogenated aromatics. Environ Health Perspect (1985) 0.87
In situ protein-DNA interactions at a dioxin-responsive enhancer associated with the cytochrome P1-450 gene. Mol Cell Biol (1987) 0.86
Dioxin-inducible, Ah receptor-dependent transcription in vitro. Proc Natl Acad Sci U S A (1990) 0.83
The molecular basis of chemical toxicity. Environ Health Perspect (1985) 0.79
Aryl hydrocarbon induction of rat cytochrome P-450d results from increased precursor RNA processing. Mol Cell Biol (1990) 0.77
Stability of the aryl hydrocarbon receptor and its regulated genes in the low activity variant of Hepa-1 cell line. Toxicol Lett (2015) 0.75
Mapping DNAase l-susceptible sites in nucleosomes labeled at the 5' ends. Cell (1976) 2.77
Control of cytochrome P1-450 gene expression by dioxin. Science (1985) 2.37
Acidic polypeptides can assemble both histones and chromatin in vitro at physiological ionic strength. Proc Natl Acad Sci U S A (1979) 2.33
Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1. J Biol Chem (1999) 2.13
A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Biol Chem (1997) 1.92
Removal of histone H1 exposes a fifty base pair DNA segment between nucleosomes. Biochemistry (1976) 1.85
Protein-DNA interactions at a dioxin-responsive enhancer. Analysis of six bona fide DNA-binding sites for the liganded Ah receptor. J Biol Chem (1993) 1.79
Xenobiotic-inducible transcription of cytochrome P450 genes. J Biol Chem (1995) 1.77
The DNA recognition site for the dioxin-Ah receptor complex. Nucleotide sequence and functional analysis. J Biol Chem (1988) 1.74
Biochemical and genetic analysis of variant mouse hepatoma cells defective in the induction of benzo(a)pyrene-metabolizing enzyme activity. J Biol Chem (1983) 1.74
Regulation of cytochrome P1-450 gene transcription by 2,3,7, 8-tetrachlorodibenzo-p-dioxin in wild type and variant mouse hepatoma cells. J Biol Chem (1984) 1.73
The Instability of Neurospora Duplication Dp(IL-->IR)H4250 , and Its Genetic Control. Genetics (1977) 1.64
Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alpha. J Biol Chem (1996) 1.59
Chemical evidence that chromatin DNA exists as 160 base pair beads interspersed with 40 base pair bridges. Nucleic Acids Res (1976) 1.57
Localization of the sites along nucleosome DNA which interact with NH2-terminal histone regions. J Biol Chem (1977) 1.51
Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer. Proc Natl Acad Sci U S A (1988) 1.50
Transcriptional activation function of the mouse Ah receptor nuclear translocator. J Biol Chem (1994) 1.43
Control of cytochrome P1-450 gene expression: analysis of a dioxin-responsive enhancer system. Proc Natl Acad Sci U S A (1986) 1.41
Dioxin-induced CYP1A1 transcription in vivo: the aromatic hydrocarbon receptor mediates transactivation, enhancer-promoter communication, and changes in chromatin structure. Mol Cell Biol (1996) 1.36
Protein-DNA interactions at recognition sites for the dioxin-Ah receptor complex. J Biol Chem (1989) 1.36
Induction of mRNA specific for cytochrome P1-450 in wild type and variant mouse hepatoma cells. J Biol Chem (1983) 1.35
The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin. Mol Cell Biol (1996) 1.34
Preparation and physical characterization of a homogeneous population of monomeric nucleosomes from HeLa cells. Nucleic Acids Res (1976) 1.30
The regulation of cytochrome P-450 gene expression. Annu Rev Pharmacol Toxicol (1986) 1.28
Transcriptional activation by the mouse Ah receptor. Interplay between multiple stimulatory and inhibitory functions. J Biol Chem (1995) 1.28
A search for complexity at the mating-type locus of Neurospora crassa. Can J Genet Cytol (1973) 1.22
Aryl hydrocarbon (benzopyrene) hydroxylase is stimulated in human lymphocytes by mitogens and benz(a)anthracene. Science (1972) 1.20
Superinduction of cytochrome P1-450 gene transcription by inhibition of protein synthesis in wild type and variant mouse hepatoma cells. J Biol Chem (1985) 1.19
Folding of DNA by histones which lack their NH2-terminal regions. J Biol Chem (1978) 1.18
The regulation of gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Pharmacol Rev (1987) 1.18
Organization and function of a dioxin-responsive enhancer. J Biol Chem (1990) 1.18
Protein-DNA interactions at a dioxin-responsive enhancer. Evidence that the transformed Ah receptor is heteromeric. J Biol Chem (1990) 1.16
Biochemical and genetic analysis of variant mouse hepatoma cells which overtranscribe the cytochrome P1-450 gene in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Biol Chem (1984) 1.13
Protein-DNA interactions at a dioxin-responsive enhancer. Mutational analysis of the DNA-binding site for the liganded Ah receptor. J Biol Chem (1992) 1.13
Control of gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Multiple dioxin-responsive domains 5'-ward of the cytochrome P1-450 gene. J Biol Chem (1986) 1.10
Superinduction of CYP1A1 transcription by cycloheximide. Role of the DNA binding site for the liganded Ah receptor. J Biol Chem (1992) 1.08
DNA binding by the heterodimeric Ah receptor. Relationship to dioxin-induced CYP1A1 transcription in vivo. J Biol Chem (1996) 1.07
Functional analysis of the transcriptional promoter for the CYP1A1 gene. Mol Cell Biol (1990) 1.07
Calcium-dependent phosphorylation of histone H3 in butyrate-treated HeLa cells. Nature (1980) 1.06
Transcription-dependent and transcription-independent nucleosome disruption induced by dioxin. Proc Natl Acad Sci U S A (1992) 1.04
Mechanism of dioxin action: Ah receptor-mediated increase in promoter accessibility in vivo. Proc Natl Acad Sci U S A (1992) 1.03
The potential role of DNA methylation in the response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Biol Chem (1989) 1.02
Use of cDNA microarrays to analyze dioxin-induced changes in human liver gene expression. Toxicol Lett (2001) 1.01
A meiotic uv-sensitive mutant that causes deletion of duplications in neurospora. Genetics (1978) 1.01
2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible aryl hydrocarbon receptor-mediated change in CYP1A1 chromatin structure occurs independently of transcription. Mol Cell Biol (1989) 1.00
Carcinogen-induced alteration of DNA structure. J Biol Chem (1981) 1.00
An apparent connection between histidine, recombination, and repair in Neurospora. Genetics (1978) 0.98
Dioxin induces localized, graded changes in chromatin structure: implications for Cyp1A1 gene transcription. Mol Cell Biol (1995) 0.97
Aryl hydrocarbon (benzo(a)pyrene) hydroxylase in human peripheral blood monocytes. Nature (1974) 0.96
Transactivation domains facilitate promoter occupancy for the dioxin-inducible CYP1A1 gene in vivo. Mol Cell Biol (1997) 0.95
2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible, Ah receptor-mediated bending of enhancer DNA. J Biol Chem (1990) 0.92
Acetylation and calcium-dependent phosphorylation of histone H3 in nuclei from butyrate-treated HeLa cells. J Biol Chem (1983) 0.92
Hypoxia-inducible mammalian gene expression analyzed in vivo at a TATA-driven promoter and at an initiator-driven promoter. J Biol Chem (1998) 0.91
Activation of transcription as a general mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin action. Mol Carcinog (1989) 0.87
In vitro metabolism of benzo(a)pyrene by human liver microsomes and lymphocytes. Cancer Res (1975) 0.87
Staphylococcal nuclease and pancreatic DNase cleave the DNA within the chromatin core particle at different sites. J Biol Chem (1977) 0.87
A novel response to dioxin. Induction of ecto-ATPase gene expression. J Biol Chem (1998) 0.87
DNase-sensitive sites in nucleosomes. Their relative suspectibilities depend on nuclease used. J Biol Chem (1977) 0.87
Changes in thymidine kinase and alpha-amylase activity during isoproterenol-stimulated DNA synthesis in mouse salivary gland. Cancer Res (1968) 0.87
In situ protein-DNA interactions at a dioxin-responsive enhancer associated with the cytochrome P1-450 gene. Mol Cell Biol (1987) 0.86
Mechanism of dioxin action: receptor-enhancer interactions in intact cells. Nucleic Acids Res (1993) 0.86
2,3,7,8-Tetrachlorodibenzo-p-dioxin receptors regulate transcription of the cytochrome P1-450 gene. J Cell Biochem (1987) 0.86
Use of gel retardation to analyze protein-DNA interactions upstream of CYPIA1 gene. Methods Enzymol (1991) 0.86
DNA sequence requirements for Ah receptor/Arnt recognition determined by in vitro transcription. Receptor (1994) 0.86
Induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase in liver cell culture by temporary inhibition of protein synthesis. J Biol Chem (1973) 0.86
Heterogeneity in the rate of benzo[a]pyrene metabolism in single cells: quantitation using flow cytometry. Mol Cell Biol (1982) 0.85
Efficient metabolism of benzo(a)pyrene at nanomolar concentrations by intact murine hepatoma cells. Cancer Res (1982) 0.85
Variation in aryl hydrocarbon (benzo(a)pyrene) hydroxylase activity in heteroploid and predominantly diploid rat liver cells in culture. J Cell Biol (1976) 0.83
The aromatic hydrocarbon receptor, transcription, and endocrine aspects of dioxin action. Vitam Horm (2000) 0.83
Activation of cytochrome P450IA1 gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin in wild-type and high-activity variant mouse hepatoma cells. Mol Carcinog (1989) 0.83
Dioxin-inducible, Ah receptor-dependent transcription in vitro. Proc Natl Acad Sci U S A (1990) 0.83
Aryl hydrocarbon (benzo(a)pyrene) hydroxylase induction in rat liver cells in culture. J Biol Chem (1974) 0.82
Novel variants in benzo(a)pyrene metabolism. Isolation by fluorescence-activated cell sorting. J Biol Chem (1981) 0.82
Reduction of GTP activation of adenylate cyclase system by its coupling to hormone receptor. J Biol Chem (1979) 0.81
Down-regulation of major histocompatibility complex Q1b gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Biol Chem (1997) 0.81
Induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase and tyrosine aminotransferase in hepatoma cells in culture. J Cell Biol (1974) 0.81
The conformation of the chromatin core particle is ionic strength-dependent. J Biol Chem (1979) 0.81
Dioxin-inducible transactivation in a chromosomal setting. Analysis of the acidic domain of the Ah receptor. J Biol Chem (2001) 0.80
Dioxin-dependent, DNA sequence-specific binding of a multiprotein complex containing the Ah receptor. Receptor (1994) 0.80
2,3,7,8-Tetrachlorodibenzo-p-dioxin induces cytochrome P450IA1 enzyme activity by activating transcription of the corresponding gene. Adv Enzyme Regul (1991) 0.77
Regulation of cytochrome P1-450 gene expression in mouse hepatoma cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Drug Metab Rev (1989) 0.76
Histone-DNA interactions in chromatin core particles. Cold Spring Harb Symp Quant Biol (1978) 0.76
Accessibility and activity of the promoter for a dioxin-inducible ecto-ATPase gene. Arch Biochem Biophys (2001) 0.76
Cytochrome P450 gene regulation. Analysis of protein-DNA interactions in situ. Methods Mol Biol (1998) 0.76
Analysis of CYP1A1 promoter function by transcription in vitro. Mol Carcinog (1991) 0.75
Aryl hydrocarbon hydroxylase and benzo[a] pyrene metabolism in rodent liver and human cels. Ann N Y Acad Sci (1980) 0.75
The control of cytochrome P-450 gene expression by dioxin. Trends Pharmacol Sci (1989) 0.75
Preparation and properties of a new DNase from Aspergillus oryzae. Biochemistry (1977) 0.75
A comparison of 14 and 12 gauge needles for core biopsy of suspicious mammographic calcification. Br J Radiol (1999) 0.75
Aryl hydrocarbon (benzo(a)pyrene) hydroxylase induction in cells in culture. Pharmacol Ther B (1979) 0.75