Published in J Biol Chem on April 04, 1997
The search for endogenous activators of the aryl hydrocarbon receptor. Chem Res Toxicol (2007) 3.68
The aryl hydrocarbon receptor complex and the control of gene expression. Crit Rev Eukaryot Gene Expr (2008) 3.06
Mutations in a new photoreceptor-pineal gene on 17p cause Leber congenital amaurosis. Nat Genet (2000) 2.85
Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism. Proc Natl Acad Sci U S A (2010) 2.46
The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo. EMBO J (2003) 1.96
The aryl hydrocarbon receptor cross-talks with multiple signal transduction pathways. Biochem Pharmacol (2008) 1.90
Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity. Mol Cell Biol (1998) 1.86
Understanding the human health effects of chemical mixtures. Environ Health Perspect (2002) 1.83
Tetratricopeptide repeat cochaperones in steroid receptor complexes. Cell Stress Chaperones (2004) 1.79
Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex. Mol Cell Biol (2002) 1.58
Developmental control of apoptosis by the immunophilin aryl hydrocarbon receptor-interacting protein (AIP) involves mitochondrial import of the survivin protein. J Biol Chem (2011) 1.54
Familial isolated pituitary adenomas (FIPA) and the pituitary adenoma predisposition due to mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene. Endocr Rev (2013) 1.40
Assessment of aryl hydrocarbon receptor complex interactions using pBEVY plasmids: expressionvectors with bi-directional promoters for use in Saccharomyces cerevisiae. Nucleic Acids Res (1998) 1.34
The hsp90 chaperone complex regulates intracellular localization of the dioxin receptor. Mol Cell Biol (2001) 1.27
Multiple roles of ligand in transforming the dioxin receptor to an active basic helix-loop-helix/PAS transcription factor complex with the nuclear protein Arnt. Mol Cell Biol (1999) 1.13
The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1. Hum Mol Genet (2002) 1.12
The Leber congenital amaurosis protein AIPL1 functions as part of a chaperone heterocomplex. Invest Ophthalmol Vis Sci (2008) 1.07
Molecular chaperones and photoreceptor function. Prog Retin Eye Res (2008) 1.04
Timing is everything: consequences of transient and sustained AhR activity. Biochem Pharmacol (2008) 1.02
Aryl hydrocarbon (Ah) receptor levels are selectively modulated by hsp90-associated immunophilin homolog XAP2. Cell Stress Chaperones (2000) 1.00
Genetic and epigenetic mutations of tumor suppressive genes in sporadic pituitary adenoma. Mol Cell Endocrinol (2013) 0.99
AIP is a mitochondrial import mediator that binds to both import receptor Tom20 and preproteins. J Cell Biol (2003) 0.99
Two forms of aryl hydrocarbon receptor type 2 in rainbow trout (Oncorhynchus mykiss). Evidence for differential expression and enhancer specificity. J Biol Chem (1999) 0.97
The role of endogenous aryl hydrocarbon receptor signaling in cardiovascular physiology. J Cardiovasc Dis Res (2011) 0.96
Carboxyl terminus of hsc70-interacting protein (CHIP) can remodel mature aryl hydrocarbon receptor (AhR) complexes and mediate ubiquitination of both the AhR and the 90 kDa heat-shock protein (hsp90) in vitro. Biochemistry (2007) 0.95
The aryl hydrocarbon receptor-interacting protein (AIP) is required for dioxin-induced hepatotoxicity but not for the induction of the Cyp1a1 and Cyp1a2 genes. J Biol Chem (2010) 0.95
Analysis of the transcriptional activation domain of the Drosophila tango bHLH-PAS transcription factor. Dev Genes Evol (2005) 0.94
A hypomorphic allele of aryl hydrocarbon receptor-associated protein-9 produces a phenocopy of the AHR-null mouse. Mol Pharmacol (2008) 0.94
Cooperation of heat shock protein 90 and p23 in aryl hydrocarbon receptor signaling. Cell Stress Chaperones (2004) 0.94
Aryl hydrocarbon receptor and kynurenine: recent advances in autoimmune disease research. Front Immunol (2014) 0.93
The tumor suppressor Kruppel-like factor 6 is a novel aryl hydrocarbon receptor DNA binding partner. J Pharmacol Exp Ther (2013) 0.93
The aryl hydrocarbon receptor is required for normal gonadotropin responsiveness in the mouse ovary. Toxicol Appl Pharmacol (2007) 0.91
Identification and characterization of genes susceptible to transcriptional cross-talk between the hypoxia and dioxin signaling cascades. Chem Res Toxicol (2006) 0.91
The co-chaperone XAP2 is required for activation of hypothalamic thyrotropin-releasing hormone transcription in vivo. EMBO Rep (2006) 0.88
Interaction networks in yeast define and enumerate the signaling steps of the vertebrate aryl hydrocarbon receptor. PLoS Biol (2004) 0.87
Hypoxia and Mucosal Inflammation. Annu Rev Pathol (2016) 0.87
Repression of Ah receptor and induction of transforming growth factor-beta genes in DEN-induced mouse liver tumors. Toxicology (2008) 0.85
Distinct roles for aryl hydrocarbon receptor nuclear translocator and ah receptor in estrogen-mediated signaling in human cancer cell lines. PLoS One (2012) 0.85
Immunological Relevance of the Coevolution of IDO1 and AHR. Front Immunol (2014) 0.84
Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms. Food Chem Toxicol (2011) 0.83
Potential roles of Arnt2 in zebrafish larval development. Zebrafish (2009) 0.83
Differential suppression of the aryl hydrocarbon receptor nuclear translocator-dependent function by an aryl hydrocarbon receptor PAS-A-derived inhibitory molecule. Biochem Pharmacol (2014) 0.80
p23 co-chaperone protects the aryl hydrocarbon receptor from degradation in mouse and human cell lines. Biochem Pharmacol (2012) 0.79
The immunophilin-like protein XAP2 is a negative regulator of estrogen signaling through interaction with estrogen receptor α. PLoS One (2011) 0.79
Cyclophilin-40 has a cellular role in the aryl hydrocarbon receptor signaling. FEBS Lett (2008) 0.79
AIP augments CARMA1-BCL10-MALT1 complex formation to facilitate NF-κB signaling upon T cell activation. Cell Commun Signal (2014) 0.78
Differential proteomics analysis reveals a role for E2F2 in the regulation of the Ahr pathway in T lymphocytes. Mol Cell Proteomics (2010) 0.78
3-Methylcholanthrene, an AhR agonist, caused cell-cycle arrest by histone deacetylation through a RhoA-dependent recruitment of HDAC1 and pRb2 to E2F1 complex. PLoS One (2014) 0.77
Ah Receptor Pathway Intricacies; Signaling Through Diverse Protein Partners and DNA-Motifs. Toxicol Res (Camb) (2015) 0.77
Aryl Hydrocarbon Receptor Interacting Protein Targets IRF7 to Suppress Antiviral Signaling and the Induction of Type I Interferon. J Biol Chem (2015) 0.77
Role of the Aryl Hydrocarbon Receptor in Colon Neoplasia. Cancers (Basel) (2015) 0.76
Mutations in a new photoreceptor-pineal gene on 17p cause leber congenital amaurosis. Nat gen 2000;24:79-83 Am J Ophthalmol (2000) 0.76
Local Generation of Kynurenines Mediates Inhibition of Neutrophil Chemotaxis by Uropathogenic Escherichia coli. Infect Immun (2016) 0.76
Functional analysis of the dioxin response elements (DREs) of the murine CYP1A1 gene promoter: beyond the core DRE sequence. Int J Mol Sci (2014) 0.76
Aryl hydrocarbon receptor antagonism and its role in rheumatoid arthritis. J Exp Pharmacol (2015) 0.75
Loss of hepatic aryl hydrocarbon receptor protein in adrenalectomized rats does not involve altered levels of the receptor's cytoplasmic chaperones. Can J Physiol Pharmacol (2013) 0.75
Stability of the aryl hydrocarbon receptor and its regulated genes in the low activity variant of Hepa-1 cell line. Toxicol Lett (2015) 0.75
Coal dust alters beta-naphthoflavone-induced aryl hydrocarbon receptor nuclear translocation in alveolar type II cells. Part Fibre Toxicol (2009) 0.75
The Complex Biology of the Aryl Hydrocarbon Receptor and Its Role in the Pituitary Gland. Horm Cancer (2017) 0.75
Mapping DNAase l-susceptible sites in nucleosomes labeled at the 5' ends. Cell (1976) 2.77
Control of cytochrome P1-450 gene expression by dioxin. Science (1985) 2.37
Acidic polypeptides can assemble both histones and chromatin in vitro at physiological ionic strength. Proc Natl Acad Sci U S A (1979) 2.33
Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1. J Biol Chem (1999) 2.13
Removal of histone H1 exposes a fifty base pair DNA segment between nucleosomes. Biochemistry (1976) 1.85
Protein-DNA interactions at a dioxin-responsive enhancer. Analysis of six bona fide DNA-binding sites for the liganded Ah receptor. J Biol Chem (1993) 1.79
Xenobiotic-inducible transcription of cytochrome P450 genes. J Biol Chem (1995) 1.77
The DNA recognition site for the dioxin-Ah receptor complex. Nucleotide sequence and functional analysis. J Biol Chem (1988) 1.74
Biochemical and genetic analysis of variant mouse hepatoma cells defective in the induction of benzo(a)pyrene-metabolizing enzyme activity. J Biol Chem (1983) 1.74
Regulation of cytochrome P1-450 gene transcription by 2,3,7, 8-tetrachlorodibenzo-p-dioxin in wild type and variant mouse hepatoma cells. J Biol Chem (1984) 1.73
Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alpha. J Biol Chem (1996) 1.59
Chemical evidence that chromatin DNA exists as 160 base pair beads interspersed with 40 base pair bridges. Nucleic Acids Res (1976) 1.57
Localization of the sites along nucleosome DNA which interact with NH2-terminal histone regions. J Biol Chem (1977) 1.51
Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer. Proc Natl Acad Sci U S A (1988) 1.50
Transcriptional activation function of the mouse Ah receptor nuclear translocator. J Biol Chem (1994) 1.43
Control of cytochrome P1-450 gene expression: analysis of a dioxin-responsive enhancer system. Proc Natl Acad Sci U S A (1986) 1.41
Protein-DNA interactions at recognition sites for the dioxin-Ah receptor complex. J Biol Chem (1989) 1.36
Dioxin-induced CYP1A1 transcription in vivo: the aromatic hydrocarbon receptor mediates transactivation, enhancer-promoter communication, and changes in chromatin structure. Mol Cell Biol (1996) 1.36
Induction of mRNA specific for cytochrome P1-450 in wild type and variant mouse hepatoma cells. J Biol Chem (1983) 1.35
The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin. Mol Cell Biol (1996) 1.34
Preparation and physical characterization of a homogeneous population of monomeric nucleosomes from HeLa cells. Nucleic Acids Res (1976) 1.30
The regulation of cytochrome P-450 gene expression. Annu Rev Pharmacol Toxicol (1986) 1.28
Transcriptional activation by the mouse Ah receptor. Interplay between multiple stimulatory and inhibitory functions. J Biol Chem (1995) 1.28
2,3,7,8-Tetrachlorodibenzo-p-dioxin receptors in wild type and variant mouse hepatoma cells. Nuclear location and strength of nuclear binding. J Biol Chem (1984) 1.24
Aryl hydrocarbon (benzopyrene) hydroxylase is stimulated in human lymphocytes by mitogens and benz(a)anthracene. Science (1972) 1.20
Superinduction of cytochrome P1-450 gene transcription by inhibition of protein synthesis in wild type and variant mouse hepatoma cells. J Biol Chem (1985) 1.19
Organization and function of a dioxin-responsive enhancer. J Biol Chem (1990) 1.18
Folding of DNA by histones which lack their NH2-terminal regions. J Biol Chem (1978) 1.18
The regulation of gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Pharmacol Rev (1987) 1.18
Protein-DNA interactions at a dioxin-responsive enhancer. Evidence that the transformed Ah receptor is heteromeric. J Biol Chem (1990) 1.16
Biochemical and genetic analysis of variant mouse hepatoma cells which overtranscribe the cytochrome P1-450 gene in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Biol Chem (1984) 1.13
Protein-DNA interactions at a dioxin-responsive enhancer. Mutational analysis of the DNA-binding site for the liganded Ah receptor. J Biol Chem (1992) 1.13
Control of gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Multiple dioxin-responsive domains 5'-ward of the cytochrome P1-450 gene. J Biol Chem (1986) 1.10
Superinduction of CYP1A1 transcription by cycloheximide. Role of the DNA binding site for the liganded Ah receptor. J Biol Chem (1992) 1.08
Functional analysis of the transcriptional promoter for the CYP1A1 gene. Mol Cell Biol (1990) 1.07
DNA binding by the heterodimeric Ah receptor. Relationship to dioxin-induced CYP1A1 transcription in vivo. J Biol Chem (1996) 1.07
Calcium-dependent phosphorylation of histone H3 in butyrate-treated HeLa cells. Nature (1980) 1.06
Transcription-dependent and transcription-independent nucleosome disruption induced by dioxin. Proc Natl Acad Sci U S A (1992) 1.04
Mechanism of dioxin action: Ah receptor-mediated increase in promoter accessibility in vivo. Proc Natl Acad Sci U S A (1992) 1.03
The potential role of DNA methylation in the response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Biol Chem (1989) 1.02
Use of cDNA microarrays to analyze dioxin-induced changes in human liver gene expression. Toxicol Lett (2001) 1.01
Carcinogen-induced alteration of DNA structure. J Biol Chem (1981) 1.00
2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible aryl hydrocarbon receptor-mediated change in CYP1A1 chromatin structure occurs independently of transcription. Mol Cell Biol (1989) 1.00
Dioxin induces localized, graded changes in chromatin structure: implications for Cyp1A1 gene transcription. Mol Cell Biol (1995) 0.97
Aryl hydrocarbon (benzo(a)pyrene) hydroxylase in human peripheral blood monocytes. Nature (1974) 0.96
Transactivation domains facilitate promoter occupancy for the dioxin-inducible CYP1A1 gene in vivo. Mol Cell Biol (1997) 0.95
Acetylation and calcium-dependent phosphorylation of histone H3 in nuclei from butyrate-treated HeLa cells. J Biol Chem (1983) 0.92
2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible, Ah receptor-mediated bending of enhancer DNA. J Biol Chem (1990) 0.92
Hypoxia-inducible mammalian gene expression analyzed in vivo at a TATA-driven promoter and at an initiator-driven promoter. J Biol Chem (1998) 0.91
Activation of transcription as a general mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin action. Mol Carcinog (1989) 0.87
A novel response to dioxin. Induction of ecto-ATPase gene expression. J Biol Chem (1998) 0.87
In vitro metabolism of benzo(a)pyrene by human liver microsomes and lymphocytes. Cancer Res (1975) 0.87
Staphylococcal nuclease and pancreatic DNase cleave the DNA within the chromatin core particle at different sites. J Biol Chem (1977) 0.87
Changes in thymidine kinase and alpha-amylase activity during isoproterenol-stimulated DNA synthesis in mouse salivary gland. Cancer Res (1968) 0.87
DNase-sensitive sites in nucleosomes. Their relative suspectibilities depend on nuclease used. J Biol Chem (1977) 0.87
Use of gel retardation to analyze protein-DNA interactions upstream of CYPIA1 gene. Methods Enzymol (1991) 0.86
Mechanism of dioxin action: receptor-enhancer interactions in intact cells. Nucleic Acids Res (1993) 0.86
In situ protein-DNA interactions at a dioxin-responsive enhancer associated with the cytochrome P1-450 gene. Mol Cell Biol (1987) 0.86
DNA sequence requirements for Ah receptor/Arnt recognition determined by in vitro transcription. Receptor (1994) 0.86
2,3,7,8-Tetrachlorodibenzo-p-dioxin receptors regulate transcription of the cytochrome P1-450 gene. J Cell Biochem (1987) 0.86
Induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase in liver cell culture by temporary inhibition of protein synthesis. J Biol Chem (1973) 0.86
Efficient metabolism of benzo(a)pyrene at nanomolar concentrations by intact murine hepatoma cells. Cancer Res (1982) 0.85
Heterogeneity in the rate of benzo[a]pyrene metabolism in single cells: quantitation using flow cytometry. Mol Cell Biol (1982) 0.85
The aromatic hydrocarbon receptor, transcription, and endocrine aspects of dioxin action. Vitam Horm (2000) 0.83
Dioxin-inducible, Ah receptor-dependent transcription in vitro. Proc Natl Acad Sci U S A (1990) 0.83
Activation of cytochrome P450IA1 gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin in wild-type and high-activity variant mouse hepatoma cells. Mol Carcinog (1989) 0.83
Variation in aryl hydrocarbon (benzo(a)pyrene) hydroxylase activity in heteroploid and predominantly diploid rat liver cells in culture. J Cell Biol (1976) 0.83
Novel variants in benzo(a)pyrene metabolism. Isolation by fluorescence-activated cell sorting. J Biol Chem (1981) 0.82
Aryl hydrocarbon (benzo(a)pyrene) hydroxylase induction in rat liver cells in culture. J Biol Chem (1974) 0.82
Induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase and tyrosine aminotransferase in hepatoma cells in culture. J Cell Biol (1974) 0.81
Reduction of GTP activation of adenylate cyclase system by its coupling to hormone receptor. J Biol Chem (1979) 0.81
Down-regulation of major histocompatibility complex Q1b gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Biol Chem (1997) 0.81
The conformation of the chromatin core particle is ionic strength-dependent. J Biol Chem (1979) 0.81
Dioxin-dependent, DNA sequence-specific binding of a multiprotein complex containing the Ah receptor. Receptor (1994) 0.80
Dioxin-inducible transactivation in a chromosomal setting. Analysis of the acidic domain of the Ah receptor. J Biol Chem (2001) 0.80
2,3,7,8-Tetrachlorodibenzo-p-dioxin induces cytochrome P450IA1 enzyme activity by activating transcription of the corresponding gene. Adv Enzyme Regul (1991) 0.77
Cytochrome P450 gene regulation. Analysis of protein-DNA interactions in situ. Methods Mol Biol (1998) 0.76
Accessibility and activity of the promoter for a dioxin-inducible ecto-ATPase gene. Arch Biochem Biophys (2001) 0.76
Histone-DNA interactions in chromatin core particles. Cold Spring Harb Symp Quant Biol (1978) 0.76
A comparison of 14 and 12 gauge needles for core biopsy of suspicious mammographic calcification. Br J Radiol (1999) 0.75
Aryl hydrocarbon hydroxylase and benzo[a] pyrene metabolism in rodent liver and human cels. Ann N Y Acad Sci (1980) 0.75
The control of cytochrome P-450 gene expression by dioxin. Trends Pharmacol Sci (1989) 0.75
Preparation and properties of a new DNase from Aspergillus oryzae. Biochemistry (1977) 0.75
Analysis of CYP1A1 promoter function by transcription in vitro. Mol Carcinog (1991) 0.75
Aryl hydrocarbon (benzo(a)pyrene) hydroxylase induction in cells in culture. Pharmacol Ther B (1979) 0.75