Published in Am J Hum Genet on November 01, 1984
Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility. Proc Natl Acad Sci U S A (1988) 4.19
Genetic heterogeneity, modes of inheritance, and risk estimates for a joint study of Caucasians with insulin-dependent diabetes mellitus. Am J Hum Genet (1988) 2.88
Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study. Proc Natl Acad Sci U S A (1988) 2.19
Relative predispositional effects (RPEs) of marker alleles with disease: HLA-DR alleles and Graves disease. Am J Hum Genet (1989) 2.03
The HLA class I A locus affects susceptibility to type 1 diabetes. Hum Immunol (2002) 1.98
HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium. Diabetes (2010) 1.62
Genetics of the HLA region in the prediction of type 1 diabetes. Curr Diab Rep (2011) 1.30
T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin. Proc Natl Acad Sci U S A (1998) 1.28
HLA DPA1, DPB1 alleles and haplotypes contribute to the risk associated with type 1 diabetes: analysis of the type 1 diabetes genetics consortium families. Diabetes (2010) 1.26
HLA-DQ primarily confers protection and HLA-DR susceptibility in type I (insulin-dependent) diabetes studied in population-based affected families and controls. Am J Hum Genet (1993) 1.19
Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1. Diabetes Obes Metab (2009) 0.98
Type 1 diabetes risk for human leukocyte antigen (HLA)-DR3 haplotypes depends on genotypic context: association of DPB1 and HLA class I loci among DR3- and DR4-matched Italian patients and controls. Hum Immunol (2008) 0.94
Multiple DNA variant association analysis: application to the insulin gene region in type I diabetes. Am J Hum Genet (1994) 0.90
Insulin-dependent diabetes mellitus: a model for the study of multifactorial disorders. Am J Hum Genet (1988) 0.90
Conditional genotype analysis: detecting secondary disease loci in linkage disequilibrium with a primary disease locus. BMC Proc (2007) 0.90
Genetic variation within the HLA class III influences T1D susceptibility conferred by high-risk HLA haplotypes. Genes Immun (2010) 0.86
Evaluation of IgA deficiency in Sardinians indicates a susceptibility gene is encoded within the HLA class III region. Clin Exp Immunol (1998) 0.85
Conditional meta-analysis stratifying on detailed HLA genotypes identifies a novel type 1 diabetes locus around TCF19 in the MHC. Hum Genet (2010) 0.82
A new model defines the minimal set of polymorphism in HLA-DQ and -DR that determines susceptibility and resistance to autoimmune diabetes. Biol Direct (2008) 0.80
A T cell receptor beta chain polymorphism is associated with patients developing insulin-dependent diabetes after the age of 20 years. Clin Exp Immunol (1990) 0.78
HLA Class II Allele, Haplotype, and Genotype Associations with Type 1 Diabetes in Benin: A Pilot Study. J Diabetes Res (2017) 0.75
HL-A and disease associations--a survey. Transplant Rev (1975) 2.87
Structure of crossreactive human histocompatibility antigens HLA-A28 and HLA-A2: possible implications for the generation of HLA polymorphism. Proc Natl Acad Sci U S A (1982) 2.36
The genetic susceptibility to type 1 (insulin-dependent) diabetes: analysis of the HLA-DR association. Diabetologia (1983) 2.04
HLA-D region beta-chain DNA endonuclease fragments differ between HLA-DR identical healthy and insulin-dependent diabetic individuals. Nature (1983) 1.99
Investigation of the mode of inheritance of the HLA associated diseases by the method of antigen genotype frequencies among diseased individuals. Tissue Antigens (1983) 1.97
HLA genotype distribution and genetic models of insulin-dependent diabetes mellitus. Ann Hum Genet (1981) 1.78
HLA genotypic study of insulin-dependent diabetes the excess of DR3/DR4 heterozygotes allows rejection of the recessive hypothesis. Diabetes (1983) 1.45
HLA-D and -DR antigens in genetic analysis of insulin dependent diabetes mellitus. Diabetologia (1981) 1.43
A haplotype study of HLA complex with special reference to the HLA-DR series and to Bf. C2 and glyoxalase I polymorphisms. Tissue Antigens (1978) 1.35
HLA genotype studies in juvenile insulin-dependent diabetes. Diabetologia (1980) 1.34
HLA haplotype study of 53 juvenile insulin-dependent diabetic (I.D.D.) families. Tissue Antigens (1982) 1.19
Juvenile-onset diabetes HLA-A, -B, -C, and -DR alloantigens. Diabetes (1979) 1.13
HLA-D--related (DRw) antigens in juvenile diabetes mellitus. Diabetes (1979) 1.12
HLA-A, B, C, DR antigens, Bf, C4 and glyoxalase I (GLO) polymorphisms in French Basques with insulin-dependent diabetes mellitus (IDDM). Tissue Antigens (1982) 1.04
Population genetic analyses of insulin dependent diabetes mellitus using HLA allele frequencies. Clin Genet (1983) 0.98
Juvenile diabetes mellitus and the HLA system. Transplant Proc (1979) 0.94
Ia-Type alloantigens and humoral autoimmune responsiveness in insulin-dependent diabetes mellitus. Metabolism (1979) 0.92
HLA-Dw antigens in unrelated juvenile, insulin-dependent diabetics. Tissue Antigens (1979) 0.91
HLA-DR specifications in Japanese with juvenile-onset insulin-dependent diabetes mellitus. Diabetes (1982) 0.91
HLA-DR specificities among black Americans with juvenile-onset diabetes. N Engl J Med (1979) 0.88
HLA-DRw antigens in Mexican-American and Black-American diabetic patients. Diabetes (1980) 0.84
HLA-DR antigens and unique serologic reactions in juvenile-onset diabetes mellitus. Transplant Proc (1978) 0.81
HLA associations with insulin-dependent diabetes mellitus in a sample of the American Black population. Tissue Antigens (1981) 0.81
The effect of a selected locus on linked neutral loci. Genetics (1977) 4.53
Determining the mode of inheritance of RFLP-associated diseases using the affected sib-pair method. Am J Hum Genet (1986) 3.49
Influence of blood lead on the ability and attainment of children in Edinburgh. Lancet (1987) 3.08
The role of HLA class II genes in insulin-dependent diabetes mellitus: molecular analysis of 180 Caucasian, multiplex families. Am J Hum Genet (1996) 2.90
Properties of equilibria in multi-locus genetic systems. Genetics (1977) 2.63
A two locus model for juvenile diabetes. Ann Hum Genet (1980) 2.63
Measuring the strength of associations between HLA antigens and diseases. Tissue Antigens (1981) 2.63
Evidence for balancing selection at HLA. Genetics (1983) 2.35
After the smoke has cleared: evaluation of the impact of a new national smoke-free law in New Zealand. Tob Control (2008) 2.35
A two-locus neutrality test: applications to humans, E. coli and lodgepole pine. Genetics (1986) 2.34
Detecting disease-predisposing variants: the haplotype method. Am J Hum Genet (1997) 2.33
The affected sib method. IV. Sib trios. Ann Hum Genet (1985) 2.22
High blood pressure treatment facilities. Survey in greater New York area. N Y State J Med (1979) 2.18
Efficacy of dexmedetomidine compared with midazolam for sedation in adult intensive care patients: a systematic review. Br J Anaesth (2013) 2.17
HLA-Bw60 increases susceptibility to ankylosing spondylitis in HLA-B27+ patients. Arthritis Rheum (1989) 2.14
Association mapping of disease loci, by use of a pooled DNA genomic screen. Am J Hum Genet (1997) 2.07
A review of theoretical aspects of HLA and disease associations. Theor Popul Biol (1981) 2.06
Relative predispositional effects (RPEs) of marker alleles with disease: HLA-DR alleles and Graves disease. Am J Hum Genet (1989) 2.03
Investigation of the mode of inheritance of the HLA associated diseases by the method of antigen genotype frequencies among diseased individuals. Tissue Antigens (1983) 1.97
Disequilibrium pattern analysis. I. Theory. Genetics (1987) 1.92
Homozygous parent affected sib pair method for detecting disease predisposing variants: application to insulin dependent diabetes mellitus. Genet Epidemiol (1993) 1.91
Differentiation between African populations is evidenced by the diversity of alleles and haplotypes of HLA class I loci. Tissue Antigens (2004) 1.86
Identifying complex disease genes: progress and paradigms. Nat Genet (1994) 1.84
The changing epidemiology of infantile hypertrophic pyloric stenosis in Scotland. Arch Dis Child (2008) 1.79
How selection shapes variation of the human major histocompatibility complex: a review. Ann Hum Genet (2001) 1.75
Crimean-Congo hemorrhagic fever in Europe: current situation calls for preparedness. Euro Surveill (2010) 1.69
The HLA class II locus DPB1 can influence susceptibility to type 1 diabetes. Diabetes (2000) 1.69
MHC microsatellite diversity and linkage disequilibrium among common HLA-A, HLA-B, DRB1 haplotypes: implications for unrelated donor hematopoietic transplantation and disease association studies. Tissue Antigens (2005) 1.65
Ontario. Proliferative and necrotizing pneumonia (PNP) of swine: the Ontario situation. Can Vet J (1991) 1.63
PyPop update--a software pipeline for large-scale multilocus population genomics. Tissue Antigens (2007) 1.60
Investigating the HLA component in rheumatoid arthritis: an additive (dominant) mode of inheritance is rejected, a recessive mode is preferred. Genet Epidemiol (1991) 1.60
New smoke-free environments legislation stimulates calls to a national Quitline. Tob Control (2005) 1.53
The affected sib method. II. The intermediate model. Ann Hum Genet (1983) 1.51
Killing the canary: the international epidemiology of the homicide of media workers. J Epidemiol Community Health (2008) 1.50
The affected sib method. I. Statistical features of the affected sib-pair method. Genetics (1985) 1.49
Responding to new severe diseases--the case for routine hospital surveillance and clinical networks in Europe. Euro Surveill (2010) 1.49
Deaths from international terrorism compared with road crash deaths in OECD countries. Inj Prev (2005) 1.47
Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27. Am J Hum Genet (1995) 1.42
Contrasting evolutionary histories among tightly linked HLA loci. Am J Hum Genet (1986) 1.39
Third order linkage disequilibrium. Tissue Antigens (1984) 1.32
Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8. Hum Mol Genet (1996) 1.31
A community standard for immunogenomic data reporting and analysis: proposal for a STrengthening the REporting of Immunogenomic Studies statement. Tissue Antigens (2011) 1.31
Constrained disequilibrium values and hitchhiking in a three-locus system. Genetics (1998) 1.27
HLA diversity, differentiation, and haplotype evolution in Mesoamerican Natives. Hum Immunol (2001) 1.27
Extended DR3-D6S273-HLA-B haplotypes are associated with increased susceptibility to type 1 diabetes in US Caucasians. Tissue Antigens (2005) 1.25
Three-allele synergistic mixed model for insulin-dependent diabetes mellitus. Diabetes (1986) 1.24
Once-daily, controlled-release tramadol and sustained-release diclofenac relieve chronic pain due to osteoarthritis: a randomized controlled trial. Pain Res Manag (2008) 1.21
African Swine Fever virus. Brief review. Arch Virol (1983) 1.20
HLA class II DR-DQ amino acids and insulin-dependent diabetes mellitus: application of the haplotype method. Am J Hum Genet (1997) 1.19
Neutrophil bactericidal function in diabetes mellitus: evidence for association with blood glucose control. Diabet Med (1995) 1.18
Genetic epidemiology. Annu Rev Public Health (1984) 1.17
How do tobacco retail displays affect cessation attempts? Findings from a qualitative study. Tob Control (2010) 1.16
HLA haplotype associations with disease. Tissue Antigens (1979) 1.15
Maternal-fetal interactions and the maintenance of HLA polymorphism. Genetics (1988) 1.14
Estimating missed government tax revenue from foreign tobacco: survey of discarded cigarette packs. Tob Control (2009) 1.13
Genetics of rheumatoid arthritis. Tissue Antigens (1986) 1.13
Three-locus systems impose additional constraints on pairwise disequilibria. Genetics (1991) 1.12
Association between type 1 diabetes age of onset and HLA among sibling pairs. Diabetes (1999) 1.12
Common chimpanzees have greater diversity than humans at two of the three highly polymorphic MHC class I genes. Immunogenetics (2000) 1.11
Testing for segregation distortion in the HLA complex. Biometrics (1994) 1.11
Susceptibility to insulin-dependent diabetes mellitus maps to a locus (IDDM11) on human chromosome 14q24.3-q31. Genomics (1996) 1.10
Evolution of HLA class II molecules: Allelic and amino acid site variability across populations. Genetics (1999) 1.10
Second-hand smoke at work: the exposure, perceptions and attitudes of bar and restaurant workers to environmental tobacco smoke. Aust N Z J Public Health (2001) 1.10
Modeling of HLA class II susceptibility to Type I diabetes reveals an effect associated with DPB1. Genet Epidemiol (2001) 1.09
Disequilibrium pattern analysis. II. Application to Danish HLA A and B locus data. Genetics (1987) 1.08
Additive susceptibility to insulin-dependent diabetes conferred by HLA-DQB1 and insulin genes. Autoimmunity (1994) 1.08
EuroNHID checklists for the assessment of high-level isolation units and referral centres for highly infectious diseases: results from the pilot phase of a European survey. Clin Microbiol Infect (2009) 1.06
HLA class II associations with rheumatic heart disease are more evident and consistent among clinically homogeneous patients. Circulation (1999) 1.05
HLA-A, -B, -C, -DRB1 allele and haplotype frequencies in an African American population. Tissue Antigens (2007) 1.04
Framing obesity: the framing contest between industry and public health at the New Zealand inquiry into obesity. Obes Rev (2011) 1.03
A model of contagious bovine pleuropneumonia transmission dynamics in East Africa. Prev Vet Med (2005) 1.03
Intelligence and fertility: The Scottish 1947 survey. Eugen Rev (1950) 1.01
D6S265*15 marks a DRB1*15, DQB1*0602 haplotype associated with attenuated protection from type 1 diabetes mellitus. Diabetologia (2005) 1.00
A randomized, double-blind, 8-week crossover study of once-daily controlled-release tramadol versus immediate-release tramadol taken as needed for chronic noncancer pain. Clin Ther (2007) 0.99
The affected sib method. III. Selection and recombination. Am J Hum Genet (1984) 0.99
Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1. Diabetes Obes Metab (2009) 0.98
A heterogeneous population model for contagious bovine pleuropneumonia transmission and control in pastoral communities of East Africa. Prev Vet Med (2005) 0.98
Evidence for an HLA-C-like locus in the orangutan Pongo pygmaeus. Immunogenetics (1999) 0.96
Oilseed rape as a potent antigen. Lancet (1990) 0.95
On distinguishing unique combinations in biological sequences. J Comput Biol (1996) 0.95
Tumor necrosis factor a microsatellite polymorphism is associated with rheumatoid arthritis severity through an interaction with the HLA-DRB1 shared epitope. Arthritis Rheum (1999) 0.94
Selection, hitchhiking and disequilibrium analysis at three linked loci with application to HLA data. Genetics (1991) 0.94
Tests of random mating for a highly polymorphic locus: application to HLA data. Biometrics (1995) 0.94
14th International HLA and Immunogenetics Workshop: report on the HLA component of type 1 diabetes. Tissue Antigens (2007) 0.94
A comprehensive search for segregation distortion in HLA. Hum Immunol (1987) 0.94
Infection control practices in facilities for highly infectious diseases across Europe. J Hosp Infect (2012) 0.93
African-American HLA class II allele and haplotype diversity. Tissue Antigens (1997) 0.92
Pseudomembranous colitis after treatment with metronidazole. Br Med J (Clin Res Ed) (1981) 0.92
HLA and IDDM predisposition: new aspects. Genet Epidemiol Suppl (1986) 0.91
The variance for the disequilibrium coefficient in the individual Hardy-Weinberg test. Biometrics (1999) 0.91
The genotypic distribution among non-insulin-dependent diabetes mellitus (NIDDM) patients of a restriction fragment length polymorphism. Am J Hum Genet (1984) 0.90
Locus and population specific evolution in HLA class II genes. Ann Hum Genet (1999) 0.90
Does genetic anticipation occur in familial rheumatoid arthritis? Ann Rheum Dis (1994) 0.89
Gene conversion in the evolution of both the H-2 and Qa class I genes of the murine major histocompatibility complex. Genetics (1990) 0.89
Genetic anticipation and musculoskeletal disease. Ann Rheum Dis (1994) 0.88
Population samples and genotyping technology. Tissue Antigens (2007) 0.88
How much downside? Quantifying the relative harm from tobacco taxation. J Epidemiol Community Health (2004) 0.87
Analysis of maternal-offspring HLA compatibility, parent-of-origin and non-inherited maternal effects for the classical HLA loci in type 1 diabetes. Diabetes Obes Metab (2009) 0.87
Porcine reproductive and respiratory syndrome virus identification in proliferative and necrotizing pneumonia cases from Ontario. Can Vet J (1994) 0.87