Published in Brain Res on September 05, 1983
Neurotensin in human small cell lung carcinoma. Br J Cancer (1984) 0.90
Alpha-synuclein in Lewy bodies. Nature (1997) 20.83
Neurodegenerative tauopathies. Annu Rev Neurosci (2001) 9.53
alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc Natl Acad Sci U S A (1998) 8.41
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proc Natl Acad Sci U S A (1998) 6.13
Paradoxical activation of Raf by a novel Raf inhibitor. Chem Biol (1999) 4.98
Diet and risk factors for coronary heart disease in Asians in northwest London. Lancet (1985) 4.83
Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature (1987) 4.59
Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation. Proc Natl Acad Sci U S A (2000) 3.86
Striatal interneurones: chemical, physiological and morphological characterization. Trends Neurosci (1995) 3.65
Identification of two distinct synucleins from human brain. FEBS Lett (1994) 3.61
Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding. Neuron (1993) 3.45
Roles of nitric oxide in tumor growth. Proc Natl Acad Sci U S A (1995) 3.28
Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies. Neurosci Lett (1998) 3.26
Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404. J Neurosci Res (1994) 3.26
The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region. EMBO J (1992) 3.04
Primary afferent tachykinins are required to experience moderate to intense pain. Nature (1998) 2.97
Altered nociception, analgesia and aggression in mice lacking the receptor for substance P. Nature (1998) 2.90
Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution. Chem Biol (1998) 2.73
Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur. Neuroscience (2002) 2.57
Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cord. Nat Med (2000) 2.54
The mas oncogene encodes an angiotensin receptor. Nature (1988) 2.53
Transmission of chronic nociception by spinal neurons expressing the substance P receptor. Science (1999) 2.43
Alzheimer's disease amyloid propagation by a template-dependent dock-lock mechanism. Biochemistry (2000) 2.37
Tau protein pathology in neurodegenerative diseases. Trends Neurosci (1998) 2.37
Multiple opiate receptor sites on primary afferent fibres. Nature (1980) 2.34
Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation. J Biol Chem (1998) 2.32
Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons. Neuroscience (2000) 2.28
Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly. FEBS Lett (1998) 2.26
The molecular dynamics of pain control. Nat Rev Neurosci (2001) 2.21
Neurochemical and cellular reorganization of the spinal cord in a murine model of bone cancer pain. J Neurosci (1999) 2.19
Amphiphysin heterodimers: potential role in clathrin-mediated endocytosis. Mol Biol Cell (1997) 2.12
Use of a drug-resistant mutant of stress-activated protein kinase 2a/p38 to validate the in vivo specificity of SB 203580. FEBS Lett (1999) 2.05
The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Ann N Y Acad Sci (2000) 2.03
A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease. J Neurosci Res (2000) 1.97
Projection subtypes of rat neostriatal matrix cells revealed by intracellular injection of biocytin. J Neurosci (1990) 1.96
Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP. Proc Natl Acad Sci U S A (1996) 1.94
Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein. Acta Neuropathol (2000) 1.92
Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia. Cell Death Differ (1998) 1.92
Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments. Proc Natl Acad Sci U S A (1997) 1.89
A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin. FEBS Lett (1999) 1.88
Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease. Proc Natl Acad Sci U S A (1988) 1.87
High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands. Am J Hum Genet (1999) 1.87
Effect of SB 203580 on the activity of c-Raf in vitro and in vivo. Oncogene (1999) 1.86
Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging. Neuropathol Appl Neurobiol (2015) 1.86
Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes. Neurobiol Dis (2000) 1.84
Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype. Exp Neurol (1994) 1.84
Intracellular recording of identified neostriatal patch and matrix spiny cells in a slice preparation preserving cortical inputs. J Neurophysiol (1989) 1.81
Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro. Curr Biol (1999) 1.81
Synthetic filaments assembled from C-terminally truncated alpha-synuclein. FEBS Lett (1998) 1.79
Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform. EMBO J (1995) 1.77
Two classes of cortical GABA neurons defined by differential calcium binding protein immunoreactivities. Exp Brain Res (1989) 1.77
Differential expression of immediate early genes in the hippocampus and spinal cord. Neuron (1990) 1.76
AChE-stained horizontal sections of the rat brain in stereotaxic coordinates. J Neurosci Methods (1980) 1.74
Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. Proc Natl Acad Sci U S A (1994) 1.74
Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17. Proc Natl Acad Sci U S A (1999) 1.73
Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau. J Biol Chem (1995) 1.70
Sensory physiology, anatomy and immunohistochemistry of Rohon-Beard neurones in embryos of Xenopus laevis. J Physiol (1984) 1.68
Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo. J Neurosci (1998) 1.68
NMDA-receptor regulation of substance P release from primary afferent nociceptors. Nature (1997) 1.65
A novel mutation at position +12 in the intron following exon 10 of the tau gene in familial frontotemporal dementia (FTD-Kumamoto) Ann Neurol (2000) 1.65
Light pulses that shift rhythms induce gene expression in the suprachiasmatic nucleus. Science (1990) 1.65
Expression and localization of alpha-adaptin isoforms. J Cell Sci (1995) 1.62
Comparative distribution of voltage-gated sodium channel proteins in human brain. Brain Res Mol Brain Res (2001) 1.60
Point substitution in the central hydrophobic cluster of a human beta-amyloid congener disrupts peptide folding and abolishes plaque competence. Biochemistry (1996) 1.58
Diversity in mammalian tachykinin peptidergic neurons: multiple peptides, receptors, and regulatory mechanisms. FASEB J (1990) 1.51
Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition. J Biol Chem (1999) 1.50
Biochemical and anatomical observations on the degeneration of peptide-containing primary afferent neurons after neonatal capsaicin. Neuroscience (1981) 1.50
Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau. J Neuropathol Exp Neurol (1999) 1.49
1H NMR of A beta amyloid peptide congeners in water solution. Conformational changes correlate with plaque competence. Biochemistry (1995) 1.48
The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs. FEBS Lett (1992) 1.45
A Schwann cell mitogen accompanying regeneration of motor neurons. Nature (1997) 1.44
Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7. Biochem J (2000) 1.44
Epitope mapping of LB509, a monoclonal antibody directed against human alpha-synuclein. Neurosci Lett (1999) 1.42
Abnormal tau-containing filaments in neurodegenerative diseases. J Struct Biol (2000) 1.42
Different configurational states of beta-amyloid and their distributions relative to plaques and tangles in Alzheimer disease. Proc Natl Acad Sci U S A (1990) 1.42
Reversible in vitro growth of Alzheimer disease beta-amyloid plaques by deposition of labeled amyloid peptide. Proc Natl Acad Sci U S A (1992) 1.41
Vitamin D status in different subgroups of British Asians. Br Med J (1976) 1.40
Comparison of the neurofibrillary pathology in Alzheimer's disease and familial presenile dementia with tangles. Acta Neuropathol (1996) 1.39
Tau pathology in a family with dementia and a P301L mutation in tau. J Neuropathol Exp Neurol (1999) 1.38
SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases. FEBS Lett (1996) 1.37
A beta deposition inhibitor screen using synthetic amyloid. Nat Biotechnol (1997) 1.37
Gene expression profiling in the post-mortem human brain--no cause for dismay. J Chem Neuroanat (2001) 1.36
The GABAB receptor interacts directly with the related transcription factors CREB2 and ATFx. Proc Natl Acad Sci U S A (2000) 1.36
Distribution of voltage-gated sodium channel alpha-subunit and beta-subunit mRNAs in human hippocampal formation, cortex, and cerebellum. J Comp Neurol (2000) 1.34
Expression pattern of human P2Y receptor subtypes: a quantitative reverse transcription-polymerase chain reaction study. Biochim Biophys Acta (2001) 1.33
Inflammation increases the distribution of dorsal horn neurons that internalize the neurokinin-1 receptor in response to noxious and non-noxious stimulation. J Neurosci (1997) 1.33
Substance P activation of enteric neurons in response to intraluminal Clostridium difficile toxin A in the rat ileum. Gastroenterology (1996) 1.32
Spinal substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain states. J Neurosci (1999) 1.32
Blockade of nerve sprouting and neuroma formation markedly attenuates the development of late stage cancer pain. Neuroscience (2010) 1.31
Rewarding effects of opiates are absent in mice lacking the receptor for substance P. Nature (2000) 1.31
Decreased neuronal nitric oxide synthase messenger RNA and somatostatin messenger RNA in the striatum of Huntington's disease. Neuroscience (1996) 1.30
Modulation of in vivo striatal transmitter release by nitric oxide and cyclic GMP. J Neurochem (1994) 1.29
The binding of [3H]mepyramine to histamine H1 receptors in guinea-pig brain. J Neurochem (1978) 1.28
Expression and localization of endothelin receptors: implications for the involvement of peripheral glia in nociception. J Neurosci (2001) 1.28
Distribution of neuropeptide Y-like immunoreactivity in the rat central nervous system--II. Immunohistochemical analysis. Neuroscience (1986) 1.28
Relationship of neuronal nitric oxide synthase immunoreactivity to GnRH neurons in the ovariectomized and intact female rat. J Neuroendocrinol (1996) 1.27