| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
The fluid mosaic model of the structure of cell membranes.
|
Science
|
1972
|
37.43
|
|
2
|
Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte interactions.
|
Proc Natl Acad Sci U S A
|
1974
|
7.95
|
|
3
|
The molecular organization of membranes.
|
Annu Rev Biochem
|
1974
|
7.13
|
|
4
|
Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431.
|
Proc Natl Acad Sci U S A
|
1978
|
5.91
|
|
5
|
Vinculin: a cytoskeletal target of the transforming protein of Rous sarcoma virus.
|
Cell
|
1981
|
5.74
|
|
6
|
Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranes.
|
Proc Natl Acad Sci U S A
|
1980
|
4.90
|
|
7
|
Improved procedures for immunoferritin labeling of ultrathin frozen sections.
|
J Cell Biol
|
1976
|
4.58
|
|
8
|
Filamin, a new high-molecular-weight protein found in smooth muscle and non-muscle cells.
|
Proc Natl Acad Sci U S A
|
1975
|
4.38
|
|
9
|
Antibody-induced linkages of plasma membrane proteins to intracellular actomyosin-containing filaments in cultured fibroblasts.
|
Proc Natl Acad Sci U S A
|
1977
|
4.23
|
|
10
|
Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound.
|
Proc Natl Acad Sci U S A
|
1982
|
4.17
|
|
11
|
Immunoelectron microscope studies of membrane-microfilament interactions: distributions of alpha-actinin, tropomyosin, and vinculin in intestinal epithelial brush border and chicken gizzard smooth muscle cells.
|
J Cell Biol
|
1981
|
4.15
|
|
12
|
Transmembrane interactions and the mechanism of capping of surface receptors by their specific ligands.
|
Proc Natl Acad Sci U S A
|
1977
|
4.04
|
|
13
|
Passage of an integral membrane protein, the vesicular stomatitis virus glycoprotein, through the Golgi apparatus en route to the plasma membrane.
|
Proc Natl Acad Sci U S A
|
1981
|
3.95
|
|
14
|
Immunoelectron microscopic studies of the sites of cell-substratum and cell-cell contacts in cultured fibroblasts.
|
J Cell Biol
|
1982
|
3.92
|
|
15
|
Ferritin-conjugated plant agglutinins as specific saccharide stains for electron microscopy: application to saccharides bound to cell membranes.
|
Proc Natl Acad Sci U S A
|
1971
|
3.90
|
|
16
|
Phosphotyrosine-containing proteins are concentrated in focal adhesions and intercellular junctions in normal cells.
|
Proc Natl Acad Sci U S A
|
1985
|
3.76
|
|
17
|
Intracellular distributions of mechanochemical proteins in cultured fibroblasts.
|
Proc Natl Acad Sci U S A
|
1977
|
3.63
|
|
18
|
Associations of elements of the Golgi apparatus with microtubules.
|
J Cell Biol
|
1984
|
3.42
|
|
19
|
Reversion from transformed to normal phenotype by inhibition of protein synthesis in rat kidney cells infected with a temperature-sensitive mutant of Rous sarcoma virus.
|
Proc Natl Acad Sci U S A
|
1976
|
3.38
|
|
20
|
Altered distributions of the cytoskeletal proteins vinculin and alpha-actinin in cultured fibroblasts transformed by Rous sarcoma virus.
|
Proc Natl Acad Sci U S A
|
1980
|
3.29
|
|
21
|
The directed migration of eukaryotic cells.
|
Annu Rev Cell Biol
|
1986
|
3.28
|
|
22
|
Protein conformation in cell membrane preparations as studied by optical rotatory dispersion and circular dichroism.
|
Proc Natl Acad Sci U S A
|
1966
|
3.16
|
|
23
|
Sequence and domain structure of talin.
|
Nature
|
1990
|
2.98
|
|
24
|
Antibody active sites and immunoglobulin molecules.
|
Science
|
1966
|
2.98
|
|
25
|
The localization of spectrin on the inner surface of human red blood cell membranes by ferritin-conjugated antibodies.
|
J Cell Biol
|
1971
|
2.96
|
|
26
|
Immunocytochemical localization of alpha-actinin in intestinal epithelial cells.
|
Proc Natl Acad Sci U S A
|
1979
|
2.86
|
|
27
|
Polarization of the Golgi apparatus and the microtubule-organizing center within cloned natural killer cells bound to their targets.
|
Proc Natl Acad Sci U S A
|
1983
|
2.85
|
|
28
|
Association of mitochondria with microtubules in cultured cells.
|
Proc Natl Acad Sci U S A
|
1978
|
2.85
|
|
29
|
Cell biology of cytotoxic and helper T cell functions: immunofluorescence microscopic studies of single cells and cell couples.
|
Annu Rev Immunol
|
1989
|
2.83
|
|
30
|
Ultrastructure of chicken cardiac muscle as studied by double immunolabeling in electron microscopy.
|
Proc Natl Acad Sci U S A
|
1981
|
2.76
|
|
31
|
Effect of microtubule assembly status on the intracellular processing and surface expression of an integral protein of the plasma membrane.
|
J Cell Biol
|
1984
|
2.68
|
|
32
|
Immunoelectron microscopic studies of the intracellular transport of the membrane glycoprotein (G) of vesicular stomatitis virus in infected Chinese hamster ovary cells.
|
J Cell Biol
|
1983
|
2.62
|
|
33
|
Identification of a developmentally regulated protein-tyrosine kinase by using anti-phosphotyrosine antibodies to screen a cDNA expression library.
|
Proc Natl Acad Sci U S A
|
1989
|
2.60
|
|
34
|
The participation of alpha-actinin in the capping of cell membrane components.
|
Cell
|
1979
|
2.58
|
|
35
|
On the mechanism of ATP-induced shape changes in human erythrocyte membranes. II. The role of ATP.
|
J Cell Biol
|
1977
|
2.54
|
|
36
|
An improved procedure for immunoelectron microscopy: ultrathin plastic embedding of immunolabeled ultrathin frozen sections.
|
Proc Natl Acad Sci U S A
|
1984
|
2.50
|
|
37
|
Membrane insertion at the leading edge of motile fibroblasts.
|
Proc Natl Acad Sci U S A
|
1983
|
2.45
|
|
38
|
Molecular biology of cellular membranes with applications to immunology.
|
Adv Immunol
|
1974
|
2.43
|
|
39
|
Alteration of the conformation of proteins in red blood cell membranes and in solution by fixatives used in electron microscopy.
|
J Cell Biol
|
1968
|
2.42
|
|
40
|
A general method for the specific staining of intracellular antigens with ferritin-antibody conjugates.
|
Proc Natl Acad Sci U S A
|
1970
|
2.31
|
|
41
|
Distribution of saccharide residues on membrane fragments from a myeloma-cell homogenate: its implications for membrane biogenesis.
|
Proc Natl Acad Sci U S A
|
1972
|
2.29
|
|
42
|
Detection and ultrastructural localization of human smooth muscle myosin-like molecules in human non-muscle cells by specific antibodies.
|
Proc Natl Acad Sci U S A
|
1975
|
2.29
|
|
43
|
The antibody-induced clustering and endocytosis of HLA antigens on cultured human fibroblasts.
|
Cell
|
1980
|
2.27
|
|
44
|
Mitochondria are associated with microtubules and not with intermediate filaments in cultured fibroblasts.
|
Proc Natl Acad Sci U S A
|
1982
|
2.23
|
|
45
|
Iron-dextran antibody conjugates: General method for simultaneous staining of two components in high-resolution immunoelectron microscopy.
|
Proc Natl Acad Sci U S A
|
1979
|
2.22
|
|
46
|
On the mechanism of ATP-induced shape changes in human erythrocyte membranes. I. The role of the spectrin complex.
|
J Cell Biol
|
1977
|
2.20
|
|
47
|
Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide.
|
Proc Natl Acad Sci U S A
|
1982
|
2.18
|
|
48
|
Bifunctional imidoesters as cross-linking reagents.
|
Biochem Biophys Res Commun
|
1966
|
2.14
|
|
49
|
Dynamic membrane-cytoskeletal interactions: specific association of integrin and talin arises in vivo after phorbol ester treatment of peripheral blood lymphocytes.
|
Proc Natl Acad Sci U S A
|
1988
|
2.12
|
|
50
|
Concanavalin-A-induced transmembrane linkage of concanavalin A surface receptors to intracellular myosin-containing filaments.
|
Proc Natl Acad Sci U S A
|
1976
|
2.09
|
|
51
|
Immunoferritin localization of intracellular antigens: the use of ultracryotomy to obtain ultrathin sections suitable for direct immunoferritin staining.
|
Proc Natl Acad Sci U S A
|
1973
|
2.07
|
|
52
|
Market-based reform: what to regulate and by whom.
|
Health Aff (Millwood)
|
1995
|
2.04
|
|
53
|
Coclustering of CD4 (L3T4) molecule with the T-cell receptor is induced by specific direct interaction of helper T cells and antigen-presenting cells.
|
Proc Natl Acad Sci U S A
|
1987
|
2.04
|
|
54
|
Covalent labeling of active sites.
|
Adv Protein Chem
|
1967
|
2.03
|
|
55
|
Talin is phosphorylated on tyrosine in chicken embryo fibroblasts transformed by Rous sarcoma virus.
|
Proc Natl Acad Sci U S A
|
1986
|
1.98
|
|
56
|
The specific direct interaction of helper T cells and antigen-presenting B cells.
|
Proc Natl Acad Sci U S A
|
1986
|
1.98
|
|
57
|
On the mechanism of unidirectional killing in mixtures of two cytotoxic T lymphocytes. Unidirectional polarization of cytoplasmic organelles and the membrane-associated cytoskeleton in the effector cell.
|
J Exp Med
|
1986
|
1.92
|
|
58
|
The specific direct interaction of helper T cells and antigen-presenting B cells. II. Reorientation of the microtubule organizing center and reorganization of the membrane-associated cytoskeleton inside the bound helper T cells.
|
J Exp Med
|
1987
|
1.90
|
|
59
|
On the nature of crossreactions observed with antibodies directed to defined epitopes.
|
Proc Natl Acad Sci U S A
|
1982
|
1.89
|
|
60
|
Interaction of filamin with f-actin in solution.
|
Proc Natl Acad Sci U S A
|
1977
|
1.87
|
|
61
|
Association of microtubules and intermediate filaments in chicken gizzard cells as detected by double immunofluorescence.
|
Proc Natl Acad Sci U S A
|
1980
|
1.87
|
|
62
|
Transmembrane linkage of fibronectin to intracellular actin-containing filaments in cultured human fibroblasts.
|
Ann N Y Acad Sci
|
1978
|
1.79
|
|
63
|
The specific interaction of helper T cells and antigen-presenting B cells. IV. Membrane and cytoskeletal reorganizations in the bound T cell as a function of antigen dose.
|
J Exp Med
|
1989
|
1.78
|
|
64
|
Fibronectin is not present in the focal adhesions formed between normal cultured fibroblasts and their substrata.
|
Proc Natl Acad Sci U S A
|
1980
|
1.76
|
|
65
|
ON DISSOCIATION AND RECOMBINATION OF HUMAN ADULT HEMOGLOBINS A, S, AND C.
|
Proc Natl Acad Sci U S A
|
1958
|
1.71
|
|
66
|
Relationships of the spectrin complex of human erythrocyte membranes to the actomyosins of muscle cells.
|
Biochemistry
|
1976
|
1.70
|
|
67
|
Molecular changes in the membranes of mouse erythroid cells accompanying differentiation.
|
Cell
|
1979
|
1.66
|
|
68
|
Distributions of vimentin and desmin in developing chick myotubes in vivo. I. Immunofluorescence study.
|
J Cell Biol
|
1984
|
1.65
|
|
69
|
The reorientation of the Golgi apparatus and the microtubule-organizing center in the cytotoxic effector cell is a prerequisite in the lysis of bound target cells.
|
J Mol Cell Immunol
|
1985
|
1.62
|
|
70
|
Quantitative two-dimensional ultrastructural distribution of Rh o (D) antigenic sites on human erythrocyte membranes.
|
Proc Natl Acad Sci U S A
|
1971
|
1.60
|
|
71
|
Association of microtubules and intermediate filaments in normal fibroblasts and its disruption upon transformation by a temperature-sensitive mutant of Rous sarcoma virus.
|
Proc Natl Acad Sci U S A
|
1981
|
1.57
|
|
72
|
A single-payer system in Jackson Hole clothing.
|
Health Aff (Millwood)
|
1994
|
1.57
|
|
73
|
The mechanism of photoaffinity labeling.
|
Proc Natl Acad Sci U S A
|
1973
|
1.57
|
|
74
|
Lysosomes are associated with microtubules and not with intermediate filaments in cultured fibroblasts.
|
Proc Natl Acad Sci U S A
|
1984
|
1.56
|
|
75
|
Mechanochemical proteins, cell motility and cell-cell contacts: the localization of mechanochemical proteins inside cultured cells at the edge of an in vitro "wound".
|
J Cell Physiol
|
1979
|
1.55
|
|
76
|
Anomalous interaction of the acetylcholine receptor protein with the nonionic detergent Triton X-114.
|
Proc Natl Acad Sci U S A
|
1985
|
1.54
|
|
77
|
The generation of antihapten antibodies with electrophoretically homogeneous L chains.
|
Proc Natl Acad Sci U S A
|
1968
|
1.52
|
|
78
|
Biological membranes as bilayer couples. III. Compensatory shape changes induced in membranes.
|
J Cell Biol
|
1976
|
1.52
|
|
79
|
Participation of histocompatibility antigens in capping of molecularly independent cell surface components by their specific antibodies.
|
Proc Natl Acad Sci U S A
|
1978
|
1.51
|
|
80
|
The distribution and asymmetry of mammalian cell surface saccharides utilizing ferritin-conjugated plant agglutinins as specific saccharide stains.
|
J Cell Biol
|
1974
|
1.49
|
|
81
|
Phosphotyrosine-modified proteins are concentrated at the membranes of epithelial and endothelial cells during tissue development in chick embryos.
|
J Cell Biol
|
1988
|
1.46
|
|
82
|
Immunocytochemical localization of 140 kD cell adhesion molecules in cultured chicken fibroblasts, and in chicken smooth muscle and intestinal epithelial tissues.
|
J Histochem Cytochem
|
1985
|
1.46
|
|
83
|
On the transfer of integral proteins into membranes.
|
Proc Natl Acad Sci U S A
|
1987
|
1.45
|
|
84
|
Transmembrane interactions and the mechanisms of transport of proteins across membranes.
|
J Supramol Struct
|
1978
|
1.44
|
|
85
|
On the interactions of lipids and proteins in the red blood cell membrane.
|
Proc Natl Acad Sci U S A
|
1970
|
1.42
|
|
86
|
The solubility of amphipathic molecules in biological membranes and lipid bilayers and its implications for membrane structure.
|
Biochemistry
|
1981
|
1.42
|
|
87
|
Photo-affinity labeling of specific acetylcholine-binding sites on membranes.
|
Proc Natl Acad Sci U S A
|
1970
|
1.38
|
|
88
|
Equilibrium and kinetic effects of drugs on the shapes of human erythrocytes.
|
J Cell Biol
|
1976
|
1.37
|
|
89
|
Cell membrane formation during the cellularization of the syncytial blastoderm of Drosophila.
|
Proc Natl Acad Sci U S A
|
1995
|
1.36
|
|
90
|
Clustering and endocytosis of membrane receptors can be induced in mature erythrocytes of neonatal but not adult humans.
|
Proc Natl Acad Sci U S A
|
1976
|
1.35
|
|
91
|
Immunoelectron microscopic studies of desmin (skeletin) localization and intermediate filament organization in chicken skeletal muscle.
|
J Cell Biol
|
1983
|
1.34
|
|
92
|
The capping of lymphocytes and other cells, studied by an improved method for immunofluorescence staining of frozen sections.
|
J Cell Physiol
|
1978
|
1.33
|
|
93
|
A soluble secretory protein is first concentrated in the endoplasmic reticulum before transfer to the Golgi apparatus.
|
Proc Natl Acad Sci U S A
|
1993
|
1.32
|
|
94
|
Crosslinking and labeling of membrane proteins by transglutaminase-catalyzed reactions.
|
Proc Natl Acad Sci U S A
|
1975
|
1.29
|
|
95
|
Structure of membranes: reaction of red blood cell membranes with phospholipase C.
|
Science
|
1968
|
1.27
|
|
96
|
Thermodynamics of the binding of haptens to rabbit anit-2,4-dinitrophenyl antibodies.
|
Biochemistry
|
1971
|
1.25
|
|
97
|
Immunoelectron microscopic studies of desmin (skeletin) localization and intermediate filament organization in chicken cardiac muscle.
|
J Cell Biol
|
1983
|
1.24
|
|
98
|
Circular dichroism and the conformations of membrane proteins. Studies with red blood cell membranes.
|
Biochemistry
|
1971
|
1.24
|
|
99
|
Congestive heart failure associated with itraconazole.
|
Lancet
|
2001
|
1.23
|
|
100
|
A disulfide-bridge bifunctional imidoester as a reversible cross-linking reagent.
|
Biochem Biophys Res Commun
|
1975
|
1.22
|
|
101
|
Disulfide bonds and the translocation of proteins across membranes.
|
Proc Natl Acad Sci U S A
|
1986
|
1.20
|
|
102
|
On the translocation of proteins across membranes.
|
Proc Natl Acad Sci U S A
|
1987
|
1.18
|
|
103
|
Member-associated changes during erythropoiesis. On the mechanism of maturation of reticulocytes to erythrocytes.
|
J Supramol Struct Cell Biochem
|
1981
|
1.15
|
|
104
|
The two-dimensional topographic distribution of H-2 histocompatibility alloantigens on mouse red blood cell membranes.
|
J Cell Biol
|
1971
|
1.14
|
|
105
|
Affinity labeling of the active sites of rabbit anti-2,4-dinitrophenyl antibodies with m-nitrobenzenediazonium fluoroborate.
|
Biochemistry
|
1967
|
1.13
|
|
106
|
Genetic clues to Alzheimer's disease.
|
Science
|
1996
|
1.13
|
|
107
|
Thermodynamics of the binding of 2,4-dinitrophenyl and 2,4,6-trinitrophenyl haptens to the homologous and heterologous rabbit antibodies.
|
Biochemistry
|
1972
|
1.13
|
|
108
|
Reversion of transformed glycolysis to normal by inhibition of protein synthesis in rat kidney cells infected with temperature-sensitive mutant of Rous sarcoma virus.
|
Proc Natl Acad Sci U S A
|
1978
|
1.13
|
|
109
|
Molecular dynamics in the membranes of helper T cells.
|
Proc Natl Acad Sci U S A
|
1988
|
1.12
|
|
110
|
Subcellular localization of sterol carrier protein-2 in rat hepatocytes: its primary localization to peroxisomes.
|
J Cell Biol
|
1989
|
1.12
|
|
111
|
Comparative study of the tyrosine phosphorylation of proteins in Swiss 3T3 fibroblasts stimulated by a variety of mitogenic agents.
|
J Cell Physiol
|
1988
|
1.11
|
|
112
|
The microtubule-organizing complex and the Golgi apparatus are co-localized around the entire nuclear envelope of interphase cardiac myocytes.
|
J Cell Sci
|
1987
|
1.10
|
|
113
|
Affinity labeling of the active sites of antibodies and myeloma proteins.
|
Ann N Y Acad Sci
|
1971
|
1.08
|
|
114
|
The specific cleavage of immunoglobulin polypeptide chains at cysteinyl residues.
|
J Biol Chem
|
1968
|
1.07
|
|
115
|
Evidence for a large internal pressure in biological membranes.
|
Proc Natl Acad Sci U S A
|
1979
|
1.07
|
|
116
|
On the location and structure of the active sites of antibody molecules.
|
Proc Natl Acad Sci U S A
|
1968
|
1.07
|
|
117
|
A possible role for stable microtubules in intracellular transport from the endoplasmic reticulum to the Golgi apparatus.
|
J Cell Sci
|
1994
|
1.07
|
|
118
|
Affinity labeling of antibodies to the p-azophenyltrimethylammonium hapten and a structural relationship among antibody active sites of different specificities.
|
Biochem Biophys Res Commun
|
1965
|
1.05
|
|
119
|
The affinity-labeled residues in antibody active sites. II. Nearest-neighbor analyses.
|
Biochemistry
|
1969
|
1.05
|
|
120
|
Reorientation of the Golgi apparatus and the microtubule-organizing center inside macrophages subjected to a chemotactic gradient.
|
Cell Motil
|
1985
|
1.05
|
|
121
|
Structural changes in membranes produced by the binding of small amphipathic molecules.
|
Biochemistry
|
1984
|
1.05
|
|
122
|
Domains of receptor mobility and endocytosis in the membranes of neonatal human erythrocytes and reticulocytes are deficient in spectrin.
|
J Cell Biol
|
1979
|
1.05
|
|
123
|
An integral glycoprotein associated with the membrane attachment sites of actin microfilaments.
|
J Cell Biol
|
1985
|
1.04
|
|
124
|
An experiment eliminating the rotating carrier mechanism for the active transport of Ca ion in sarcoplasmic reticulum membranes.
|
Proc Natl Acad Sci U S A
|
1976
|
1.04
|
|
125
|
The seven-transmembrane spanning topography of the Alzheimer disease-related presenilin proteins in the plasma membranes of cultured cells.
|
Proc Natl Acad Sci U S A
|
1997
|
1.04
|
|
126
|
Distributions of vimentin and desmin in developing chick myotubes in vivo. II. Immunoelectron microscopic study.
|
J Cell Biol
|
1985
|
1.04
|
|
127
|
3-Hydroxy-3-methylglutaryl-coenzyme A reductase is present in peroxisomes in normal rat liver cells.
|
Proc Natl Acad Sci U S A
|
1985
|
1.04
|
|
128
|
Selective and unidirectional membrane redistribution of an H-2 antigen with an antibody-clustered viral antigen: relationship to mechanisms of cytotoxic T-cell interactions.
|
Proc Natl Acad Sci U S A
|
1979
|
1.02
|
|
129
|
A 200-kd protein isolated from the fascia adherens membrane domains of chicken cardiac muscle cells is detected immunologically in fibroblast focal adhesions.
|
Cell Motil
|
1983
|
1.02
|
|
130
|
Cell surface expression of the Alzheimer disease-related presenilin proteins.
|
Proc Natl Acad Sci U S A
|
1997
|
1.01
|
|
131
|
Zeugmatin: a new high molecular weight protein associated with Z lines in adult and early embryonic striated muscle.
|
J Cell Biol
|
1985
|
1.00
|
|
132
|
The structure and chemistry of mammalian cell membranes.
|
Am J Pathol
|
1971
|
1.00
|
|
133
|
Cytoskeletal organization, vinculin-phosphorylation, and fibronectin expression in transformed fibroblasts with different cell morphologies.
|
Virology
|
1986
|
1.00
|
|
134
|
Cytoskeletal targets for viral transforming proteins with tyrosine protein kinase activity.
|
Cold Spring Harb Symp Quant Biol
|
1982
|
1.00
|
|
135
|
Thermodynamics, the structure of integral membrane proteins, and transport.
|
J Supramol Struct
|
1977
|
0.98
|
|
136
|
Interstitial pneumonitis associated with sirolimus therapy in renal-transplant recipients.
|
N Engl J Med
|
2000
|
0.98
|
|
137
|
The preparation and properties of some tritiated diazonium salts and related compounds.
|
Biochemistry
|
1967
|
0.97
|
|
138
|
A critical role for the polarization of membrane recycling in cell motility.
|
Cell Motil Cytoskeleton
|
1987
|
0.97
|
|
139
|
The presenilins turned inside out: implications for their structures and functions.
|
Proc Natl Acad Sci U S A
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