Published in J Mol Biol on September 25, 1983
Structural relationships of actin, myosin, and tropomyosin revealed by cryo-electron microscopy. J Cell Biol (1987) 2.57
The dynamic distribution of fluorescent analogues of actin and myosin in protrusions at the leading edge of migrating Swiss 3T3 fibroblasts. J Cell Biol (1988) 2.14
Subunit structure of junctional feet in triads of skeletal muscle: a freeze-drying, rotary-shadowing study. J Cell Biol (1984) 1.99
Three-dimensional structure of myosin subfragment-1 from electron microscopy of sectioned crystals. J Cell Biol (1991) 1.56
The essential light chain is required for full force production by skeletal muscle myosin. Proc Natl Acad Sci U S A (1994) 1.52
The substructure of isolated and in situ outer dynein arms of sea urchin sperm flagella. J Cell Biol (1985) 1.43
Site-specific inhibition of myosin-mediated motility in vitro by monoclonal antibodies. J Cell Biol (1985) 1.31
Structural changes that occur in scallop myosin filaments upon activation. J Cell Biol (1985) 1.27
The myosin alkali light chain proteins and their genes. Biochem J (1985) 1.22
Electron cryomicroscopy of acto-myosin-S1 during steady-state ATP hydrolysis. Biophys J (1994) 1.18
A point mutation in the regulatory light chain reduces the step size of skeletal muscle myosin. Proc Natl Acad Sci U S A (2004) 1.15
Isolation of the regulatory domain of scallop myosin: role of the essential light chain in calcium binding. Proc Natl Acad Sci U S A (1990) 1.09
Imaging biological structures with the cryo atomic force microscope. Biophys J (1996) 1.09
Orientation of spin-labeled light chain-2 exchanged onto myosin cross-bridges in glycerinated muscle fibers. Biophys J (1991) 1.03
Monoclonal antibodies detect and stabilize conformational states of smooth muscle myosin. J Cell Biol (1989) 1.02
Three-dimensional reconstruction of thick filaments from Limulus and scorpion muscle. J Cell Biol (1985) 1.02
Crystallization of myosin subfragment 1. Proc Natl Acad Sci U S A (1984) 1.00
Single myosin cross-bridge orientation in cardiac papillary muscle detects lever-arm shear strain in transduction. Biochemistry (2011) 0.97
Mapping myosin light chains by immunoelectron microscopy. Use of anti-fluorescyl antibodies as structural probes. J Cell Biol (1989) 0.94
Unshadowed myosin molecules: STEM mass-maps of myosin heads. EMBO J (1984) 0.94
Dictyostelium discoideum myosin: isolation and characterization of cDNAs encoding the essential light chain. Mol Cell Biol (1988) 0.91
Oligomeric structure of the multifunctional protein CAD that initiates pyrimidine biosynthesis in mammalian cells. Proc Natl Acad Sci U S A (1985) 0.90
Rod phosphorylation favors folding in a catch muscle myosin. Proc Natl Acad Sci U S A (1987) 0.90
Cryo-atomic force microscopy of smooth muscle myosin. Biophys J (1997) 0.89
Identification of sequences necessary for the association of cardiac myosin subunits. J Cell Biol (1991) 0.88
Structure of the myosin head in solution and the effect of light chain 2 removal. Biophys J (1992) 0.88
Role of skeletal and smooth muscle myosin light chains. Biophys J (1995) 0.84
Structural models for the regulatory switch of Myosin. Biophys J (1986) 0.83
The mechanism of regulatory light chain dissociation from scallop myosin. Biochem J (1986) 0.82
Calcium-induced mechanical change in the neck domain alters the activity of plant myosin XI. J Biol Chem (2012) 0.81
Localization and topography of antigenic domains within the heavy chain of smooth muscle myosin. J Cell Biol (1985) 0.79
Electron Microscopy: From 2D to 3D Images with Special Reference to Muscle. Eur J Transl Myol (2015) 0.75
Streptococcal M protein: alpha-helical coiled-coil structure and arrangement on the cell surface. Proc Natl Acad Sci U S A (1981) 5.56
Structural relationships of actin, myosin, and tropomyosin revealed by cryo-electron microscopy. J Cell Biol (1987) 2.57
Ca(2+)-induced tropomyosin movement in Limulus thin filaments revealed by three-dimensional reconstruction. Nature (1994) 2.34
Structure of mitochondrial creatine kinase. Nature (1996) 2.33
Electron microscopy of thin filaments decorated with a Ca2+-regulated myosin. J Mol Biol (1980) 1.64
Steric-blocking by tropomyosin visualized in relaxed vertebrate muscle thin filaments. J Mol Biol (1995) 1.63
A protein that binds specifically to the M-line of skeletal muscle is identified as the muscle form of creatine kinase. Proc Natl Acad Sci U S A (1973) 1.62
Mitochondrial creatine kinase: a key enzyme of aerobic energy metabolism. Biochim Biophys Acta (1992) 1.59
Localization of creatine kinase isoenzymes in myofibrils. I. Chicken skeletal muscle. J Cell Biol (1977) 1.55
Troponin and its interactions with tropomyosin. An electron microscope study. J Mol Biol (1982) 1.48
Three-dimensional reconstruction of thin filaments decorated with a Ca2+-regulated myosin. J Mol Biol (1982) 1.40
Localization and function of M-line-bound creatine kinase. M-band model and creatine phosphate shuttle. Cell Muscle Motil (1985) 1.34
Function of M-line-bound creatine kinase as intramyofibrillar ATP regenerator at the receiving end of the phosphorylcreatine shuttle in muscle. J Biol Chem (1984) 1.33
Muscle-type MM creatine kinase is specifically bound to sarcoplasmic reticulum and can support Ca2+ uptake and regulate local ATP/ADP ratios. J Biol Chem (1990) 1.31
Site-specific inhibition of myosin-mediated motility in vitro by monoclonal antibodies. J Cell Biol (1985) 1.31
Intermolecular versus intramolecular interactions of Dictyostelium myosin: possible regulation by heavy chain phosphorylation. J Cell Biol (1989) 1.30
Sequence homology and structure predictions of the creatine kinase isoenzymes. Mol Cell Biochem (1995) 1.29
Structural changes that occur in scallop myosin filaments upon activation. J Cell Biol (1985) 1.27
Electron microscopy and image analysis of myosin filaments from scallop striated muscle. J Mol Biol (1983) 1.26
Differential effects of creatine depletion on the regulation of enzyme activities and on creatine-stimulated mitochondrial respiration in skeletal muscle, heart, and brain. Biochim Biophys Acta (1996) 1.25
The C-protein tetramer binds 230 to 240 nucleotides of pre-mRNA and nucleates the assembly of 40S heterogeneous nuclear ribonucleoprotein particles. Mol Cell Biol (1994) 1.25
Direct evidence for the control of mitochondrial respiration by mitochondrial creatine kinase in oxidative muscle cells in situ. J Biol Chem (2000) 1.23
Actin filaments in muscle: pattern of myosin and tropomyosin/troponin attachments. J Mol Biol (1978) 1.20
The molecular structure of mitochondrial contact sites. Their role in regulation of energy metabolism and permeability transition. Biofactors (1998) 1.18
Creatine kinase: the reactive cysteine is required for synergism but is nonessential for catalysis. Biochemistry (1993) 1.17
End-stabilized microtubules observed in vitro: stability, subunit, interchange, and breakage. Cell Motil Cytoskeleton (1992) 1.17
Equilibration and exchange of fluorescently labeled molecules in skinned skeletal muscle fibers visualized by confocal microscopy. Biophys J (1995) 1.16
In situ compartmentation of creatine kinase in intact sarcomeric muscle: the acto-myosin overlap zone as a molecular sieve. J Muscle Res Cell Motil (1992) 1.16
Localization of reactive cysteine residues by maleidoyl undecagold in the mitochondrial creatine kinase octamer. J Struct Biol (1995) 1.16
Mitochondrial creatine kinase mediates contact formation between mitochondrial membranes. J Biol Chem (1991) 1.12
A new myosin fragment: visualization of the regulatory domain. Nature (1984) 1.11
Further characterization of contact sites from mitochondria of different tissues: topology of peripheral kinases. Biochim Biophys Acta (1989) 1.09
The role of creatine kinase in inhibition of mitochondrial permeability transition. FEBS Lett (1997) 1.09
Three-dimensional image reconstruction of reconstituted smooth muscle thin filaments: effects of caldesmon. Biophys J (1997) 1.07
Creatine kinase activity in the Torpedo electrocyte and in the nonreceptor, peripheral v proteins from acetylcholine receptor-rich membranes. Proc Natl Acad Sci U S A (1983) 1.07
Light-chain movement and regulation in scallop myosin. Nature (1983) 1.07
Crystallization of the human, mitochondrial voltage-dependent anion-selective channel in the presence of phospholipids. J Struct Biol (1999) 1.07
Crystal structure of brain-type creatine kinase at 1.41 A resolution. Protein Sci (1999) 1.06
Differentiation in cultures derived from embryonic chicken muscle. II. Phosphorylase histochemistry and fluorescent antibody staining for creatin kinase and aldolase. Dev Biol (1976) 1.06
Heart C-protein is transiently expressed during skeletal muscle development in the embryo, but persists in cultured myogenic cells. Dev Biol (1985) 1.06
A minimal motor domain from chicken skeletal muscle myosin. J Biol Chem (1995) 1.05
Downregulation of the Na(+)-creatine cotransporter in failing human myocardium and in experimental heart failure. Circulation (1999) 1.05
3-D image reconstruction of reconstituted smooth muscle thin filaments containing calponin: visualization of interactions between F-actin and calponin. J Mol Biol (1997) 1.04
Dimer ribbons in the three-dimensional structure of sarcoplasmic reticulum. J Mol Biol (1985) 1.02
Monovalent antibodies against MM-creatine kinase remove the M line from myofibrils. Proc Natl Acad Sci U S A (1978) 1.02
Mitochondrial creatine kinase and mitochondrial outer membrane porin show a direct interaction that is modulated by calcium. J Biol Chem (2001) 1.01
Creatine supplementation in health and disease. Effects of chronic creatine ingestion in vivo: down-regulation of the expression of creatine transporter isoforms in skeletal muscle. Mol Cell Biochem (1998) 1.01
Reconstituted adenine nucleotide translocase forms a channel for small molecules comparable to the mitochondrial permeability transition pore. FEBS Lett (1998) 1.01
Functional studies with the octameric and dimeric form of mitochondrial creatine kinase. Differential pH-dependent association of the two oligomeric forms with the inner mitochondrial membrane. J Biol Chem (1990) 1.01
A molecular approach to the concerted action of kinases involved in energy homoeostasis. Biochem Soc Trans (2003) 1.00
Mitochondrial creatine kinase: a major constituent of pathological inclusions seen in mitochondrial myopathies. Proc Natl Acad Sci U S A (1994) 0.98
Mitochondrial creatine kinase from chicken brain. Purification, biophysical characterization, and generation of heterodimeric and heterooctameric molecules with subunits of other creatine kinase isoenzymes. J Biol Chem (1990) 0.98
Adult rat cardiomyocytes cultured in creatine-deficient medium display large mitochondria with paracrystalline inclusions, enriched for creatine kinase. J Cell Biol (1991) 0.98
Location and regulation of octameric mitochondrial creatine kinase in the contact sites. Biochim Biophys Acta (1991) 0.97
Structural changes of creatine kinase upon substrate binding. Biophys J (1998) 0.97
Distinct tissue specific mitochondrial creatine kinases from chicken brain and striated muscle with a conserved CK framework. Biochem Biophys Res Commun (1988) 0.97
The tryptophan residues of mitochondrial creatine kinase: roles of Trp-223, Trp-206, and Trp-264 in active-site and quaternary structure formation. Protein Sci (1994) 0.97
Mitochondrial creatine kinase from cardiac muscle and brain are two distinct isoenzymes but both form octameric molecules. J Biol Chem (1988) 0.97
Interaction of mitochondrial creatine kinase with model membranes. A monolayer study. FEBS Lett (1991) 0.96
Crystal structure of human ubiquitous mitochondrial creatine kinase. Proteins (2000) 0.96
An immunological approach to myosin light-chain function in thick filament linked regulation. 2. Effects of anti-scallop myosin light-chain antibodies. Possible regulatory role for the essential light chain. Biochemistry (1981) 0.96
Isoenzyme-specific localization of M-line bound creatine kinase in myogenic cells. J Muscle Res Cell Motil (1983) 0.95
Multiple-state equilibrium unfolding of guanidino kinases. Biochemistry (1995) 0.95
Functional aspects of the X-ray structure of mitochondrial creatine kinase: a molecular physiology approach. Mol Cell Biochem (1998) 0.95
Expression of active octameric chicken cardiac mitochondrial creatine kinase in Escherichia coli. Biochem J (1992) 0.94
Localization of creatine kinase isoenzymes in myofibrils. II. Chicken heart muscle. J Cell Biol (1977) 0.94
Kinetics of assembly and dissociation of the mitochondrial creatine kinase octamer. A fluorescence study. Biochemistry (1993) 0.94
Unshadowed myosin molecules: STEM mass-maps of myosin heads. EMBO J (1984) 0.94
Mitochondrial creatine kinase in contact sites: interaction with porin and adenine nucleotide translocase, role in permeability transition and sensitivity to oxidative damage. Biol Signals Recept (2001) 0.93
High content of creatine kinase in chicken retina: compartmentalized localization of creatine kinase isoenzymes in photoreceptor cells. Proc Natl Acad Sci U S A (1986) 0.93
Compartmentation of ATP synthesis and utilization in smooth muscle: roles of aerobic glycolysis and creatine kinase. Mol Cell Biochem (1995) 0.93
Functional aspects of creatine kinase in brain. Dev Neurosci (1993) 0.92
Creatine metabolism and the consequences of creatine depletion in muscle. Mol Cell Biochem (1995) 0.92
Human, rat and chicken small intestinal Na+ - Cl- -creatine transporter: functional, molecular characterization and localization. J Physiol (2002) 0.92
Myofibrillar interaction of cytosolic creatine kinase (CK) isoenzymes: allocation of N-terminal binding epitope in MM-CK and BB-CK. J Cell Sci (1998) 0.91
Isoenzyme-specific interaction of muscle-type creatine kinase with the sarcomeric M-line is mediated by NH(2)-terminal lysine charge-clamps. J Cell Biol (2000) 0.90
In vitro complex formation between the octamer of mitochondrial creatine kinase and porin. J Biol Chem (1994) 0.90
Novel staining pattern of skeletal muscle M-lines upon incubation with antibodies against MM-creatine kinase. J Cell Biol (1983) 0.90
Effects of creatine treatment on survival and differentiation of GABA-ergic neurons in cultured striatal tissue. J Neurochem (2005) 0.90
Creatine transporter and mitochondrial creatine kinase protein content in myopathies. Muscle Nerve (2001) 0.90
Coupling of creatine kinase to glycolytic enzymes at the sarcomeric I-band of skeletal muscle: a biochemical study in situ. J Muscle Res Cell Motil (2000) 0.90
Creatine kinase isoenzymes in spermatozoa. J Muscle Res Cell Motil (1986) 0.90
Mitochondrial creatine kinase is a prime target of peroxynitrite-induced modification and inactivation. J Biol Chem (1998) 0.89
Structure of myosin/paramyosin filaments from a molluscan smooth muscle. J Mol Biol (1983) 0.89
Subcellular localization of creatine kinase in Torpedo electrocytes: association with acetylcholine receptor-rich membranes. J Cell Biol (1985) 0.89
Novel thick filament protein of chicken pectoralis muscle: the 86 kd protein. II. Distribution and localization. J Mol Biol (1985) 0.89
Myofibrillar M-band proteins in rat skeletal muscles during development. Histochemistry (1990) 0.89
Creatine supplementation improves intracellular Ca2+ handling and survival in mdx skeletal muscle cells. FEBS Lett (1998) 0.89
Crystallization and preliminary X-ray analysis of two different forms of mitochondrial creatine kinase from chicken cardiac muscle. J Mol Biol (1990) 0.88
Structure of the mitochondrial creatine kinase octamer: high-resolution shadowing and image averaging of single molecules and formation of linear filaments under specific staining conditions. J Cell Biol (1991) 0.88
Reconstitution of active octameric mitochondrial creatine kinase from two genetically engineered fragments. Protein Sci (1996) 0.87
Melting of myosin rod as revealed by electron microscopy. II. Effects of temperature and pH on length and stability of myosin rod and its fragments. Eur J Cell Biol (1986) 0.87
The importance of the outer mitochondrial compartment in regulation of energy metabolism. Mol Cell Biochem (1995) 0.87
Phosphorylation of chicken brain-type creatine kinase affects a physiologically important kinetic parameter and gives rise to protein microheterogeneity in vivo. FEBS Lett (1990) 0.87
Brain-type creatine kinase in photoreceptor cell outer segments: role of a phosphocreatine circuit in outer segment energy metabolism and phototransduction. J Cell Sci (1993) 0.87
Differential expression and localization of brain-type and mitochondrial creatine kinase isoenzymes during development of the chicken retina: Mi-CK as a marker for differentiation of photoreceptor cells. Differentiation (1991) 0.86
Octamers of mitochondrial creatine kinase isoenzymes differ in stability and membrane binding. J Biol Chem (2000) 0.86