Published in J Cell Biol on April 01, 1985
Inhibition of kinesin-driven microtubule motility by monoclonal antibodies to kinesin heavy chains. J Cell Biol (1988) 2.69
Conserved protein domains in a myosin heavy chain gene from Dictyostelium discoideum. Proc Natl Acad Sci U S A (1986) 2.05
Immunological identification of the genes encoding the four myosin heavy chain isoforms of Caenorhabditis elegans. Proc Natl Acad Sci U S A (1986) 1.84
Topography of N-CAM structural and functional determinants. I. Classification of monoclonal antibody epitopes. J Cell Biol (1986) 1.35
Monoclonal antibodies against seven sites on the head and tail of Dictyostelium myosin. J Cell Biol (1985) 1.32
Intermolecular versus intramolecular interactions of Dictyostelium myosin: possible regulation by heavy chain phosphorylation. J Cell Biol (1989) 1.30
Expression of Dictyostelium myosin tail segments in Escherichia coli: domains required for assembly and phosphorylation. J Cell Biol (1990) 1.22
Topography of N-CAM structural and functional determinants. II. Placement of monoclonal antibody epitopes. J Cell Biol (1986) 1.18
Monoclonal antibodies binding to the tail of Dictyostelium discoideum myosin: their effects on antiparallel and parallel assembly and actin-activated ATPase activity. J Cell Biol (1986) 1.12
Expression in Escherichia coli of a functional Dictyostelium myosin tail fragment. J Cell Biol (1987) 1.11
A Dictyostelium myosin II lacking a proximal 58-kDa portion of the tail is functional in vitro and in vivo. Mol Biol Cell (1992) 1.03
Genetically engineered truncated myosin in Dictyostelium: the carboxyl-terminal regulatory domain is not required for the developmental cycle. Proc Natl Acad Sci U S A (1990) 1.01
Identification and characterization of a novel alpha-kinase with a von Willebrand factor A-like motif localized to the contractile vacuole and Golgi complex in Dictyostelium discoideum. Mol Biol Cell (2005) 0.95
A structural model for phosphorylation control of Dictyostelium myosin II thick filament assembly. J Cell Biol (1999) 0.92
Identification of functional regions on the tail of Acanthamoeba myosin-II using recombinant fusion proteins. I. High resolution epitope mapping and characterization of monoclonal antibody binding sites. J Cell Biol (1990) 0.86
The mechanism of muscular contraction. Science (1969) 14.47
Substructure of the myosin molecule. I. Subfragments of myosin by enzymic degradation. J Mol Biol (1969) 6.44
Antibody to myosin: the specific visualization of myosin-containing filaments in nonmuscle cells. Proc Natl Acad Sci U S A (1974) 5.93
Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro. J Cell Biol (1982) 5.52
Rotary shadowing of extended molecules dried from glycerol. J Ultrastruct Res (1980) 5.01
Regulation and kinetics of the actin-myosin-ATP interaction. Annu Rev Biochem (1980) 4.57
Movement of myosin-coated fluorescent beads on actin cables in vitro. Nature (1983) 3.76
On the fragmentation of monoclonal IgG1, IgG2a, and IgG2b from BALB/c mice. J Immunol (1983) 3.57
Purification and characterization of smooth muscle myosin light chain kinase. J Biol Chem (1981) 2.84
Phosphorylation of platelet myosin increases actin-activated myosin ATPase activity. Nature (1975) 2.79
Light-chain phosphorylation controls the conformation of vertebrate non-muscle and smooth muscle myosin molecules. Nature (1983) 2.73
Regulation of non-muscle myosin assembly by calmodulin-dependent light chain kinase. Nature (1980) 2.53
A bent monomeric conformation of myosin from smooth muscle. Proc Natl Acad Sci U S A (1982) 2.51
Shape and flexibility of the myosin molecule. J Mol Biol (1978) 2.45
Calcium control of actin-activated myosin adenosine triphosphatase from Dictyostelium discoideum. Proc Natl Acad Sci U S A (1976) 2.45
Regulation of myosin self-assembly: phosphorylation of Dictyostelium heavy chain inhibits formation of thick filaments. Proc Natl Acad Sci U S A (1980) 2.35
Modulator protein as a component of the myosin light chain kinase from chicken gizzard. Biochemistry (1978) 2.32
Fluctuations in polarized fluorescence: evidence that muscle cross bridges rotate repetitively during contraction. Proc Natl Acad Sci U S A (1979) 2.27
A mechanochemical mechanism for muscle contraction. Proc Natl Acad Sci U S A (1971) 1.93
Distribution of myosin isoenzymes among skeletal muscle fiber types. J Cell Biol (1979) 1.92
Millisecond time-resolved changes in x-ray reflections from contracting muscle during rapid mechanical transients, recorded using synchrotron radiation. Proc Natl Acad Sci U S A (1981) 1.84
ATP-dependent movement of myosin in vitro: characterization of a quantitative assay. J Cell Biol (1984) 1.84
Electron microscopic mapping of monoclonal antibodies on the tail region of Dictyostelium myosin. EMBO J (1982) 1.75
Tropomyosin paracrystals formed by divalent cations. Science (1966) 1.73
Effect of phosphorylation of smooth muscle myosin on actin activation and Ca2+ regulation. Proc Natl Acad Sci U S A (1977) 1.70
Monoclonal antibodies localize changes on myosin heavy chain isozymes during avian myogenesis. Cell (1983) 1.65
Distribution and properties of myosin isozymes in developing avian and mammalian skeletal muscle fibers. J Cell Biol (1982) 1.64
Electron microscopy of scallop myosin. Location of regulatory light chains. J Mol Biol (1983) 1.60
On the origin of the contractile force in skeletal muscle. Proc Natl Acad Sci U S A (1979) 1.55
Polymorphism of myosin among skeletal muscle fiber types. J Cell Biol (1977) 1.36
Monoclonal antibodies against seven sites on the head and tail of Dictyostelium myosin. J Cell Biol (1985) 1.32
Electron microscopy of myosin molecules from muscle and non-muscle sources. Proc R Soc Lond B Biol Sci (1976) 1.29
Dictyostelium myosin: characterization of chymotryptic fragments and localization of the heavy-chain phosphorylation site. J Cell Biol (1981) 1.18
Light-chain movement and regulation in scallop myosin. Nature (1983) 1.07
An immunological approach to myosin light-chain function in thick filament linked regulation. 2. Effects of anti-scallop myosin light-chain antibodies. Possible regulatory role for the essential light chain. Biochemistry (1981) 0.96
The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. J Biol Chem (1971) 35.39
Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell (1985) 13.73
Single myosin molecule mechanics: piconewton forces and nanometre steps. Nature (1994) 13.73
Tracking kinesin-driven movements with nanometre-scale precision. Nature (1988) 13.43
Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages. Cell (1997) 10.22
Single particle tracking. Analysis of diffusion and flow in two-dimensional systems. Biophys J (1991) 9.39
Purification of muscle actin. Methods Enzymol (1982) 9.11
Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination. Science (1987) 8.51
Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte interactions. Proc Natl Acad Sci U S A (1974) 7.95
Localization of cytoplasmic dynein to mitotic spindles and kinetochores. Nature (1990) 7.33
Myosin-V is a processive actin-based motor. Nature (1999) 7.13
Monoclonal antibodies for analysis of the HLA system. Immunol Rev (1979) 6.63
Analysis of a successful immune response against hepatitis C virus. Immunity (1999) 6.31
Pictures of MHC restriction. Nature (1996) 6.04
Pilus retraction powers bacterial twitching motility. Nature (2000) 5.69
Fluorescent actin filaments move on myosin fixed to a glass surface. Proc Natl Acad Sci U S A (1986) 5.67
Force of single kinesin molecules measured with optical tweezers. Science (1993) 5.57
Streptococcal M protein: alpha-helical coiled-coil structure and arrangement on the cell surface. Proc Natl Acad Sci U S A (1981) 5.56
Cytoskeletal elements of chick embryo fibroblasts revealed by detergent extraction. J Supramol Struct (1976) 5.42
Use of a monoclonal antibody (W6/32) in structural studies of HLA-A,B,C, antigens. J Immunol (1979) 5.06
Myosin-V stepping kinetics: a molecular model for processivity. Proc Natl Acad Sci U S A (2000) 5.03
Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein. J Cell Biol (1991) 5.02
Human diversity in killer cell inhibitory receptor genes. Immunity (1997) 4.82
In silico mapping of complex disease-related traits in mice. Science (2001) 4.67
Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro. Cell (1985) 4.61
Lateral mobility of integral membrane proteins is increased in spherocytic erythrocytes. Nature (1980) 4.50
A micromachined device provides a new bend on fibroblast traction forces. Proc Natl Acad Sci U S A (1997) 4.50
Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion. Cell (2000) 4.45
Myosin structure and function in cell motility. Annu Rev Cell Biol (1987) 4.33
Nonmuscle contractile proteins: the role of actin and myosin in cell motility and shape determination. Annu Rev Biochem (1977) 4.25
Two activators of microtubule-based vesicle transport. J Cell Biol (1991) 4.06
Lateral movements of membrane glycoproteins restricted by dynamic cytoplasmic barriers. Science (1991) 4.05
Cytoplasmic dynein is a minus end-directed motor for membranous organelles. Cell (1989) 4.05
Structure, function, and diversity of class I major histocompatibility complex molecules. Annu Rev Biochem (1990) 4.02
Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma. Nat Immunol (2000) 4.02
Myosin VI is a processive motor with a large step size. Proc Natl Acad Sci U S A (2001) 3.95
Biochemical and structural studies of actomyosin-like proteins from non-muscle cells. Isolation and characterization of myosin from amoebae of Dictyostelium discoideum. J Mol Biol (1974) 3.91
Organelle, bead, and microtubule translocations promoted by soluble factors from the squid giant axon. Cell (1985) 3.87
Purification of muscle actin. Methods Cell Biol (1982) 3.87
Origin of proteins in sporulation. Annu Rev Biochem (1968) 3.86
Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. Immunity (1997) 3.84
Myosin step size. Estimation from slow sliding movement of actin over low densities of heavy meromyosin. J Mol Biol (1990) 3.80
Quantitative measurements of force and displacement using an optical trap. Biophys J (1996) 3.78
Movement of myosin-coated fluorescent beads on actin cables in vitro. Nature (1983) 3.76
Transcription by single molecules of RNA polymerase observed by light microscopy. Nature (1991) 3.63
The neck region of the myosin motor domain acts as a lever arm to generate movement. Proc Natl Acad Sci U S A (1996) 3.61
Movement of organelles along filaments dissociated from the axoplasm of the squid giant axon. Cell (1985) 3.59
On the fragmentation of monoclonal IgG1, IgG2a, and IgG2b from BALB/c mice. J Immunol (1983) 3.57
Single microtubules from squid axoplasm support bidirectional movement of organelles. Cell (1985) 3.55
Assays for actin sliding movement over myosin-coated surfaces. Methods Enzymol (1991) 3.53
Nomenclature for the major histocompatibility complexes of different species: a proposal. Immunogenetics (1990) 3.53
Membrane tether formation from blebbing cells. Biophys J (1999) 3.47
Myosin subfragment-1 is sufficient to move actin filaments in vitro. Nature (1987) 3.44
The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor. J Exp Med (1995) 3.43
Deformation and flow of membrane into tethers extracted from neuronal growth cones. Biophys J (1996) 3.42
IMGT/HLA database--a sequence database for the human major histocompatibility complex. Tissue Antigens (2000) 3.41
Mechanical properties of neuronal growth cone membranes studied by tether formation with laser optical tweezers. Biophys J (1995) 3.39
Guilt by association: HLA-B27 and ankylosing spondylitis. Immunol Today (1990) 3.38
Integrin-cytoskeletal interactions in migrating fibroblasts are dynamic, asymmetric, and regulated. J Cell Biol (1993) 3.37
Single-molecule biomechanics with optical methods. Science (1999) 3.35
The microtubule-dependent formation of a tubulovesicular network with characteristics of the ER from cultured cell extracts. Cell (1988) 3.34
Forward transport of glycoproteins on leading lamellipodia in locomoting cells. Nature (1989) 3.34
Control of nonmuscle myosins by phosphorylation. Annu Rev Biochem (1992) 3.34
Characterization of a monoclonal anti-beta 2-microglobulin antibody and its use in the genetic and biochemical analysis of major histocompatibility antigens. Eur J Immunol (1979) 3.27
Capping of surface receptors and concomitant cortical tension are generated by conventional myosin. Nature (1989) 3.24
Nomenclature for factors of the HLA system, 2010. Tissue Antigens (2010) 3.22
HLA-A and B polymorphisms predate the divergence of humans and chimpanzees. Nature (1988) 3.21
Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus. Immunity (2001) 3.18
Cell spreading and lamellipodial extension rate is regulated by membrane tension. J Cell Biol (2000) 3.18
Gene replacement in Dictyostelium: generation of myosin null mutants. EMBO J (1989) 3.04
Partial purification and some properties of BB7.2. A cytotoxic monoclonal antibody with specificity for HLA-A2 and a variant of HLA-A28. Hum Immunol (1981) 3.01
Matrix control of protein diffusion in biological membranes. Proc Natl Acad Sci U S A (1981) 2.96
Effect of sonication on the structure of lecithin bilayers. Biochemistry (1972) 2.94
Characteristics of a membrane reservoir buffering membrane tension. Biophys J (1999) 2.93
Monoclonal antibody to a human histocompatibility alloantigen, HLA-A2. Nature (1978) 2.93
Biochemical and structural studies of actomyosin-like proteins from non-muscle cells. II. Purification, properties, and membrane association of actin from amoebae of Dictyostelium discoideum. J Biol Chem (1974) 2.87
Targeting of motor proteins. Science (1996) 2.80
Direct binding and functional transfer of NK cell inhibitory receptors reveal novel patterns of HLA-C allotype recognition. J Immunol (1998) 2.79
Immunology. Deconstructing the MHC. Nature (1992) 2.76
Monomorphic anti-HLA-A,B,C monoclonal antibodies detecting molecular subunits and combinatorial determinants. J Immunol (1982) 2.74
Structure of HLA antigens: amino-acid and carbohydrate compositions and NH2-terminal sequences of four antigen preparations. Proc Natl Acad Sci U S A (1976) 2.71
Cytochalasin B, its interaction with actin and actomyosin from muscle (cell movement-microfilaments-rabbit striated muscle). Proc Natl Acad Sci U S A (1972) 2.68
Cytochalasin inhibits the rate of elongation of actin filament fragments. J Cell Biol (1979) 2.67
Dictyostelium myosin heavy chain phosphorylation sites regulate myosin filament assembly and localization in vivo. Cell (1993) 2.61
NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules. J Exp Med (1994) 2.59
Actin microheterogeneity in chick embryo fibroblasts. Proc Natl Acad Sci U S A (1977) 2.57
Structural relationships of actin, myosin, and tropomyosin revealed by cryo-electron microscopy. J Cell Biol (1987) 2.57
A monoclonal antibody that recognizes an antigenic determinant shared by HLA A2 and B17. Hum Immunol (1980) 2.56
Calcium control of actin-activated myosin adenosine triphosphatase from Dictyostelium discoideum. Proc Natl Acad Sci U S A (1976) 2.45
Three-dimensional atomic model of F-actin decorated with Dictyostelium myosin S1. Nature (1993) 2.44
Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes. Science (1995) 2.44
Cell migration does not produce membrane flow. J Cell Biol (1990) 2.42
Selective regulation of integrin--cytoskeleton interactions by the tyrosine kinase Src. Nat Cell Biol (1999) 2.41
Chemical subdomains within the kinetochore domain of isolated CHO mitotic chromosomes. J Cell Biol (1991) 2.40
Ligand binding regulates the directed movement of beta1 integrins on fibroblasts. Nature (1996) 2.40
Biochemical and structural characterization of actin from Dictyostelium discoideum. J Biol Chem (1978) 2.39
Rapid cloning of HLA-A,B cDNA by using the polymerase chain reaction: frequency and nature of errors produced in amplification. Proc Natl Acad Sci U S A (1990) 2.37
Mechanism of action of cytochalasin: evidence that it binds to actin filament ends. J Cell Biol (1981) 2.36
Regulation of myosin self-assembly: phosphorylation of Dictyostelium heavy chain inhibits formation of thick filaments. Proc Natl Acad Sci U S A (1980) 2.35