Published in Arch Biochem Biophys on January 01, 1984
Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics. Chem Rev (2011) 1.93
Cloning and characterization of LCB1, a Saccharomyces gene required for biosynthesis of the long-chain base component of sphingolipids. J Bacteriol (1991) 1.53
Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure. Nat Med (2015) 1.46
The SPTLC3 subunit of serine palmitoyltransferase generates short chain sphingoid bases. J Biol Chem (2009) 1.38
Genetic evidence for ATP-dependent endoplasmic reticulum-to-Golgi apparatus trafficking of ceramide for sphingomyelin synthesis in Chinese hamster ovary cells. J Cell Biol (1999) 1.37
Sphingolipids are required for mammalian epidermal barrier function. Inhibition of sphingolipid synthesis delays barrier recovery after acute perturbation. J Clin Invest (1991) 1.32
Increased sphingomyelin content of plasma lipoproteins in apolipoprotein E knockout mice reflects combined production and catabolic defects and enhances reactivity with mammalian sphingomyelinase. J Clin Invest (1998) 1.23
Dietary fat interacts with PCBs to induce changes in lipid metabolism in mice deficient in low-density lipoprotein receptor. Environ Health Perspect (2005) 1.21
Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity. J Bacteriol (1992) 1.21
Ceramide: a common pathway for atherosclerosis? Atherosclerosis (2007) 1.19
Mammalian ORMDL proteins mediate the feedback response in ceramide biosynthesis. J Biol Chem (2012) 1.17
An improved method to determine serine palmitoyltransferase activity. J Lipid Res (2009) 1.09
Spinal ceramide modulates the development of morphine antinociceptive tolerance via peroxynitrite-mediated nitroxidative stress and neuroimmune activation. J Pharmacol Exp Ther (2008) 1.07
Phospholipid and sphingolipid metabolism in Leishmania. Mol Biochem Parasitol (2009) 1.07
Sphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamage. Biochem Biophys Res Commun (2007) 1.05
Regulation of the sphingosine-recycling pathway for ceramide generation by oxidative stress, and its role in controlling c-Myc/Max function. Biochem J (2006) 1.04
Acid Sphingomyelinase Deficiency Prevents Diet-induced Hepatic Triacylglycerol Accumulation and Hyperglycemia in Mice. J Biol Chem (2008) 1.04
Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity. J Lipid Res (2009) 1.00
Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexans. Prog Lipid Res (2013) 0.96
Involvement of ceramide in ethanol-induced apoptotic neurodegeneration in the neonatal mouse brain. J Neurochem (2010) 0.91
The rate of sphingomyelin synthesis de novo is influenced by the level of cholesterol in cultured human skin fibroblasts. Biochem J (1998) 0.91
The external aldimine form of serine palmitoyltransferase: structural, kinetic, and spectroscopic analysis of the wild-type enzyme and HSAN1 mutant mimics. J Biol Chem (2009) 0.89
An introduction to sphingolipid metabolism and analysis by new technologies. Neuromolecular Med (2010) 0.88
The twists and turns of sphingolipid pathway in glucose regulation. Biochimie (2010) 0.87
The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. J Biol Chem (2014) 0.87
Altering pyrroloquinoline quinone nutritional status modulates mitochondrial, lipid, and energy metabolism in rats. PLoS One (2011) 0.87
Characterization of secretory sphingomyelinase activity, lipoprotein sphingolipid content and LDL aggregation in ldlr-/- mice fed on a high-fat diet. Biosci Rep (2012) 0.85
Localization of epidermal sphingolipid synthesis and serine palmitoyl transferase activity: alterations imposed by permeability barrier requirements. Arch Dermatol Res (1995) 0.85
Sphingolipidomics of A2780 human ovarian carcinoma cells treated with synthetic retinoids. J Lipid Res (2010) 0.85
Lactosylceramide causes endothelial dysfunction in porcine coronary arteries and human coronary artery endothelial cells. Med Sci Monit (2009) 0.83
Importance of the sphingoid base length for the membrane properties of ceramides. Biophys J (2012) 0.79
Regulation of mitochondrial ceramide distribution by members of the BCL-2 family. J Lipid Res (2015) 0.79
Inhibition of de novo ceramide biosynthesis by FTY720 protects rat retina from light-induced degeneration. J Lipid Res (2013) 0.79
Regulation of ceramide generation during macrophage apoptosis by ASMase and de novo synthesis. Biochim Biophys Acta (2015) 0.78
Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology. Biochim Biophys Acta (2009) 0.78
Cutaneous lipid synthesis during late fetal development in the rat. Arch Dermatol Res (1995) 0.78
Identification of a novel L-serine analog that suppresses osteoclastogenesis in vitro and bone turnover in vivo. J Biol Chem (2009) 0.77
Ceramide response post-photodamage is absent after treatment with HA14-1. Biochem Biophys Res Commun (2006) 0.77
Novel functional association of serine palmitoyltransferase subunit 1-A peptide in sphingolipid metabolism with cytochrome P4501A1 transactivation and proliferative capacity of the human Glioma LN18 brain tumor cell line. Int J Environ Res Public Health (2006) 0.76
Novel interconnections in lipid metabolism revealed by overexpression of sphingomyelin synthase-1. J Biol Chem (2017) 0.75
Modulation of sphingolipid metabolism with calorie restriction enhances insulin action in skeletal muscle. J Nutr Biochem (2015) 0.75
Sphingosine Toxicity in EAE and MS: Evidence for Ceramide Generation via Serine-Palmitoyltransferase Activation. Neurochem Res (2017) 0.75
Molecular classification of cutaneous malignant melanoma by gene expression profiling. Nature (2000) 15.53
ACID-BASE EQUIVALENCE OF THE BLOOD IN DISEASES ASSOCIATED WITH HYPERGLOBULINEMIA; WITH SPECIAL REFERENCE TO LYMPHOGRANULOMA INGUINALE AND MULTIPLE MYELOMA. J Clin Invest (1936) 6.18
Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors. Cancer Res (1987) 4.44
Assessing the clinical effectiveness of preventive maneuvers: analytic principles and systematic methods in reviewing evidence and developing clinical practice recommendations. A report by the Canadian Task Force on the Periodic Health Examination. J Clin Epidemiol (1990) 3.88
Simultaneous genotyping and species identification using hybridization pattern recognition analysis of generic Mycobacterium DNA arrays. Genome Res (1998) 3.85
Evidence that the src gene product of Rous sarcoma virus is membrane associated. Virology (1980) 3.71
Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1. Nat Neurosci (2002) 3.28
Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. J Biol Chem (1991) 3.20
Randomised trial of intravenous immunoglobulin G, intravenous anti-D, and oral prednisone in childhood acute immune thrombocytopenic purpura. Lancet (1994) 3.12
Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets. J Biol Chem (1986) 3.05
Cytokine production at the site of disease in human tuberculosis. Infect Immun (1993) 3.04
Cytokine production induced by Mycobacterium tuberculosis lipoarabinomannan. Relationship to chemical structure. J Immunol (1992) 3.03
Malignant urachal lesions. J Urol (1984) 2.99
Gastric pacing improves emptying and symptoms in patients with gastroparesis. Gastroenterology (1998) 2.78
Functions of cytoplasmic fibers in intracellular movements in BHK-21 cells. J Cell Biol (1978) 2.74
New approaches for studying and exploiting an old protuberance, the plant trichome. Ann Bot (2004) 2.54
Sphingolipid metabolism and cell growth regulation. FASEB J (1996) 2.53
Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. Proc Natl Acad Sci U S A (1996) 2.50
Changes in microfilament organization and surface topogrophy upon transformation of chick embryo fibroblasts with Rous sarcoma virus. Proc Natl Acad Sci U S A (1976) 2.38
Oxythiamine and dehydroepiandrosterone inhibit the nonoxidative synthesis of ribose and tumor cell proliferation. Cancer Res (1997) 2.35
Phorbol myristate acetate stimulates microtubule and 10-nm filament extension and lysosome redistribution in mouse macrophages. J Cell Biol (1980) 2.31
Determinants of increased energy expenditure in HIV-infected women. Am J Clin Nutr (1998) 2.21
Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology. Toxicol Appl Pharmacol (1997) 2.19
Selective modulation of human natural killer cells in vivo after prolonged infusion of low dose recombinant interleukin 2. J Clin Invest (1993) 2.18
Role of pretransplant echocardiographic evaluation in predicting outcomes following liver transplantation. Am J Transplant (2013) 2.04
Definition of distinct compartments in polarized Madin-Darby canine kidney (MDCK) cells for membrane-volume sorting, polarized sorting and apical recycling. Traffic (2000) 2.00
Advantages of mRNA amplification for microarray analysis. Biotechniques (2002) 2.00
Interleukin 12 at the site of disease in tuberculosis. J Clin Invest (1994) 1.98
Differences in intracellular location of pp60src in rat and chicken cells transformed by Rous sarcoma virus. Proc Natl Acad Sci U S A (1980) 1.91
Phorbol myristate acetate stimulates pinocytosis and membrane spreading in mouse peritoneal macrophages. J Cell Biol (1980) 1.88
Trisomy 13 detection in the first trimester of pregnancy using a chromosome-selective cell-free DNA analysis method. Ultrasound Obstet Gynecol (2012) 1.83
Involvement of microtubules and 10-nm filaments in the movement and positioning of nuclei in syncytia. J Cell Biol (1979) 1.78
Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst. J Biol Chem (1986) 1.77
Human renal carcinoma cells produce hypercalcemia in the nude mouse and a novel protein recognized by parathyroid hormone receptors. J Clin Invest (1983) 1.77
Functional consequences of posttranslational isomerization of Ser46 in a calcium channel toxin. Science (1994) 1.73
Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5. Proc Natl Acad Sci U S A (2000) 1.73
Genetic variation in the 3' non-coding region of dengue viruses. Virology (2001) 1.71
Improved outcome of respiratory syncytial virus infection in a high-risk hospitalized population of Canadian children. Pediatric Investigators Collaborative Network on Infections in Canada. J Pediatr (1992) 1.71
PHACES association: a neuroradiologic review of 17 patients. AJNR Am J Neuroradiol (2008) 1.70
Fibrillar systems in cell motility. Ciba Found Symp (1973) 1.70
Functional analysis of antigen-specific T lymphocytes by serial measurement of gene expression in peripheral blood mononuclear cells and tumor specimens. J Immunol (1999) 1.67
Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα. J Clin Invest (2014) 1.66
Interferon effects on microfilament organization, cellular fibronectin distribution, and cell motility in human fibroblasts. J Cell Biol (1980) 1.65
Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse. J Pathol (2006) 1.63
Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia. J Pharmacol Exp Ther (2008) 1.60
Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression. J Immunol (1999) 1.58
Flexible use of high-density oligonucleotide arrays for single-nucleotide polymorphism discovery and validation. Genome Res (2001) 1.55
Leukocyte counts and colonization with Ureaplasma urealyticum in preterm neonates. Clin Infect Dis (1993) 1.54
Analysis of sphingosine 1-phosphate, ceramides, and other bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. Sci STKE (2001) 1.53
Structure and expression of a membrane component of the inhibin receptor system. Endocrinology (2000) 1.53
Retention of adaptive control over varying intervals: prevention of slip- induced backward balance loss during gait. J Neurophysiol (2006) 1.52
Cytoplasmic localization of the transforming protein of Fujinami sarcoma virus: salt-sensitive association with subcellular components. J Virol (1983) 1.52
Possible mechanism for seeding of tumor during radical prostatectomy. J Urol (1993) 1.52
Quantitation of free sphingosine in liver by high-performance liquid chromatography. Anal Biochem (1988) 1.51
Binding of deoxyribonuclease I to actin: a new way to visualize microfilament bundles in nonmuscle cells. J Histochem Cytochem (1978) 1.50
Acupuncture for neck disorders. Cochrane Database Syst Rev (2006) 1.50
Amplified C lambda and c-abl genes are on the same marker chromosome in K562 leukemia cells. Proc Natl Acad Sci U S A (1983) 1.48
Digestive function after radical pancreaticoduodenectomy. Am J Surg (1969) 1.47
Suicide substrates for the alanine racemase of Escherichia coli B. Biochemistry (1978) 1.47
The Epstein-Barr virus nuclear protein SM is both a post-transcriptional inhibitor and activator of gene expression. Proc Natl Acad Sci U S A (1998) 1.47
Improvements to the differential display method for gene analysis. Biochem Biophys Res Commun (1994) 1.46
The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia. Oncogene (2012) 1.46
Adenoviral-mediated transfer of the TNF-related apoptosis-inducing ligand/Apo-2 ligand gene induces tumor cell apoptosis. J Immunol (2000) 1.45
Tyrosine phosphorylation in human neutrophil. Biochem Biophys Res Commun (1989) 1.45
Sphingolipids in food and the emerging importance of sphingolipids to nutrition. J Nutr (1999) 1.44
Paclitaxel in advanced urothelial carcinoma: its role in patients with renal insufficiency and as salvage therapy. J Urol (1996) 1.42
Isofenphos induced metabolic changes in K562 myeloid blast cells. Leuk Res (2001) 1.41
Proton nuclear magnetic resonance assignments and structural characterization of an intramolecular DNA triplex. J Mol Biol (1992) 1.41
BMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1. J Cell Physiol (2001) 1.40
Effect of methionine and vitamin B-12 on the activities of methionine biosynthetic enzymes in metJ mutants of Escherichia coli K12. Arch Biochem Biophys (1973) 1.39
Tumors of the kidney, ureter, and bladder. West J Med (1992) 1.39
The effect of benign breast biopsy on subsequent breast cancer detection practices. Oncol Nurs Forum (1994) 1.38
BK virus replication and nephropathy after alemtuzumab-induced kidney transplantation. Am J Transplant (2012) 1.38
Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide. J Biol Chem (1997) 1.37
Obesity and obesity-related secondary conditions in adolescents with intellectual/developmental disabilities. J Intellect Disabil Res (2010) 1.37
Incidental carcinoma of the prostate: a review of the literature and critical reappraisal of classification. J Urol (1980) 1.37
Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase. Neuroscience (2006) 1.37
Body composition and endocrine function in women with acquired immunodeficiency syndrome wasting. J Clin Endocrinol Metab (1997) 1.36
Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases. J Biol Chem (1986) 1.35
Recalled anxiety: from discovery to diagnosis of a benign breast mass. Oncol Nurs Forum (1995) 1.35
Immune selection after antigen-specific immunotherapy of melanoma. Surgery (1999) 1.34
Phase II study of continuous daily sunitinib dosing in patients with previously treated advanced non-small cell lung cancer. Br J Cancer (2009) 1.33
Rupture of the corpus cavernosum: surgical management. J Urol (1983) 1.32
Rotavirus-associated diarrhea in outpatient settings and child care centers. The Greater Toronto Area/Peel Region PRESI Study Group. Pediatric Rotavirus Epidemiology Study for Immunization. Arch Pediatr Adolesc Med (2000) 1.32
Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: a novel cell-mediated gene therapy. J Gene Med (2000) 1.32
Regulation of lipid biosynthesis in Saccharomyces cerevisiae by fumonisin B1. J Biol Chem (1995) 1.31
Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis. Environ Health Perspect (2001) 1.31
Apoptosis rate can be accelerated or decelerated by overexpression or reduction of the level of elongation factor-1 alpha. Exp Cell Res (1998) 1.30
High-frequency S-layer protein variation in Campylobacter fetus revealed by sapA mutagenesis. Mol Microbiol (1994) 1.29
Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. Environ Health Perspect (2001) 1.29
Comparison of broth and human serum as the diluent in the serum bactericidal test. Antimicrob Agents Chemother (1975) 1.28
Human transforming growth factor-alpha stimulates bone resorption in vitro. J Clin Invest (1985) 1.28
Hospitalization for community-acquired, rotavirus-associated diarrhea: a prospective, longitudinal, population-based study during the seasonal outbreak. The Greater Toronto Area/Peel Region PRESI Study Group. Pediatric Rotavirus Epidemiology Study for Immunization. Arch Pediatr Adolesc Med (2000) 1.28
PAX7 expression in embryonal rhabdomyosarcoma suggests an origin in muscle satellite cells. Br J Cancer (2003) 1.28
Controversial aspects of diagnosis and management of blunt abdominal trauma. Am J Surg (1966) 1.28
A high-performance liquid chromatographic method to measure sphingosine 1-phosphate and related compounds from sphingosine kinase assays and other biological samples. Anal Biochem (2000) 1.28
The significance of biliary pressure in cholangitis. Arch Surg (1969) 1.27