Computer analysis and structure prediction of nucleic acids and proteins.

PubWeight™: 1.30‹?› | Rank: Top 10%

🔗 View Article (PMC 321015)

Published in Nucleic Acids Res on January 11, 1984

Authors

M Kanehisa, P Klein, P Greif, C DeLisi

Articles by these authors

KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res (1999) 40.62

DBGET/LinkDB: an integrated database retrieval system. Pac Symp Biocomput (1998) 24.06

Whole genome sequencing of meticillin-resistant Staphylococcus aureus. Lancet (2001) 18.55

LIGAND: chemical database of enzyme reactions. Nucleic Acids Res (2000) 17.91

The GenBank nucleic acid sequence database. Comput Appl Biosci (1985) 16.50

A knowledge base for predicting protein localization sites in eukaryotic cells. Genomics (1992) 11.85

The detection and classification of membrane-spanning proteins. Biochim Biophys Acta (1985) 8.75

LIGAND: chemical database for enzyme reactions. Bioinformatics (1998) 8.36

Reconstruction of amino acid biosynthesis pathways from the complete genome sequence. Genome Res (1998) 7.03

Expert system for predicting protein localization sites in gram-negative bacteria. Proteins (1991) 6.06

T-cell antigenic sites tend to be amphipathic structures. Proc Natl Acad Sci U S A (1985) 5.05

An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1988) 4.72

A heuristic graph comparison algorithm and its application to detect functionally related enzyme clusters. Nucleic Acids Res (2000) 4.53

Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins. J Mol Biol (1987) 4.07

AAindex: amino acid index database. Nucleic Acids Res (2000) 3.83

AAindex: Amino Acid Index Database. Nucleic Acids Res (1999) 3.52

Determination of atomic desolvation energies from the structures of crystallized proteins. J Mol Biol (1997) 3.49

Efficacy of a homeopathic Crataegus preparation compared with usual therapy for mild (NYHA II) cardiac insufficiency: results of an observational cohort study. Eur J Heart Fail (2003) 3.36

DNA microarray analysis of cyanobacterial gene expression during acclimation to high light. Plant Cell (2001) 3.12

The biophysics of ligand-receptor interactions. Q Rev Biophys (1980) 3.04

Analysis of amino acid indices and mutation matrices for sequence comparison and structure prediction of proteins. Protein Eng (1996) 3.00

Genes linked by fusion events are generally of the same functional category: a systematic analysis of 30 microbial genomes. Proc Natl Acad Sci U S A (2001) 2.95

Computation with the KEGG pathway database. Biosystems (1998) 2.79

Interaction between proteins localized in membranes. Proc Natl Acad Sci U S A (1986) 2.74

Construction of a dictionary of sequence motifs that characterize groups of related proteins. Protein Eng (1992) 2.58

Two complementary methods for predicting peptides binding major histocompatibility complex molecules. J Mol Biol (1997) 2.57

Structure of the human interleukin-2 receptor gene. Science (1985) 2.43

Protein network inference from multiple genomic data: a supervised approach. Bioinformatics (2004) 2.41

Cluster analysis of amino acid indices for prediction of protein structure and function. Protein Eng (1988) 2.37

Three patterns of catamenial epilepsy. Epilepsia (1997) 2.29

Helper T-cell antigenic site identification in the acquired immunodeficiency syndrome virus gp120 envelope protein and induction of immunity in mice to the native protein using a 16-residue synthetic peptide. Proc Natl Acad Sci U S A (1987) 2.25

Effect of nonspecific forces and finite receptor number on rate constants of ligand--cell bound-receptor interactions. Proc Natl Acad Sci U S A (1981) 2.21

Organizing and computing metabolic pathway data in terms of binary relations. Pac Symp Biocomput (1997) 2.19

Homeopathic vs conventional treatment of vertigo: a randomized double-blind controlled clinical study. Arch Otolaryngol Head Neck Surg (1998) 2.14

Free energy landscapes of encounter complexes in protein-protein association. Biophys J (1999) 2.12

Kinetics of desolvation-mediated protein-protein binding. Biophys J (2000) 2.03

Protein antigenic structures recognized by T cells: potential applications to vaccine design. Immunol Rev (1987) 1.95

Use of statistical criteria for screening potential homologies in nucleic acid sequences. Nucleic Acids Res (1984) 1.85

Effect of conformational flexibility and solvation on receptor-ligand binding free energies. Biochemistry (1994) 1.78

A comparative analysis of ABC transporters in complete microbial genomes. Genome Res (1998) 1.73

Ruptured splenic artery aneurysm during pregnancy: a rare case with both maternal and fetal survival. Am J Obstet Gynecol (1999) 1.70

Predictions of gene family distributions in microbial genomes: evolution by gene duplication and modification. Phys Rev Lett (2000) 1.69

Urban-rural differences in prehospital care of major trauma. J Trauma (1997) 1.58

Mechanism of binding of multivalent immune complexes to Fc receptors. 1. Equilibrium binding. Biochemistry (1981) 1.56

Cold-regulated genes under control of the cold sensor Hik33 in Synechocystis. Mol Microbiol (2001) 1.54

Automatic detection of conserved gene clusters in multiple genomes by graph comparison and P-quasi grouping. Nucleic Acids Res (2000) 1.52

Transmembrane signaling in Dictyostelium. Methods Cell Biol (1987) 1.48

Construction and analysis of a profile library characterizing groups of structurally known proteins. Protein Sci (1996) 1.47

Helping the urban poor stay with antiretroviral HIV drug therapy. Am J Public Health (2000) 1.45

Outcome and cost analysis of scheduled versus emergency scleral buckling surgery. Ophthalmology (1992) 1.45

Prediction of protein structural class from the amino acid sequence. Biopolymers (1986) 1.41

Prediction of protein function from sequence properties. Discriminant analysis of a data base. Biochim Biophys Acta (1984) 1.40

The effect of cell size and receptor density on ligand--receptor reaction rate constants. Mol Immunol (1981) 1.39

Fat partitioning of lidocaine in tumescent liposuction. Ann Plast Surg (1999) 1.39

Strong conformational propensities enhance T cell antigenicity. J Immunol (1987) 1.39

Comparison of succinylcholine with two doses of rocuronium using a new method of monitoring neuromuscular block at the laryngeal muscles by surface laryngeal electromyography. Br J Anaesth (2000) 1.38

Characterization of genes encoding multi-domain proteins in the genome of the filamentous nitrogen-fixing Cyanobacterium anabaena sp. strain PCC 7120. DNA Res (2001) 1.37

Comparison of mitotic phenomena and effects induced by hypertonic solutions in HeLa cells. J Cell Biol (1970) 1.37

Extraction of correlated gene clusters from multiple genomic data by generalized kernel canonical correlation analysis. Bioinformatics (2003) 1.36

Paclitaxel-induced apoptosis and mitotic arrest assessed by serial fine-needle aspiration: implications for early prediction of breast cancer response to neoadjuvant treatment. Clin Cancer Res (2000) 1.33

Estimating the number of protein folds. J Mol Biol (1998) 1.33

Treatment of muscle injuries by local administration of autologous conditioned serum: a pilot study on sportsmen with muscle strains. Int J Sports Med (2004) 1.31

On the mechanism of hemolytic plaque inhibition. Immunochemistry (1974) 1.27

Prediction of membrane proteins based on classification of transmembrane segments. Protein Eng (1998) 1.26

Isolated central nervous system metastases in patients with HER2-overexpressing advanced breast cancer treated with first-line trastuzumab-based therapy. Ann Oncol (2005) 1.25

Hydration-state-responsive proteins link cold and drought stress in spinach. Planta (1992) 1.23

mRNA is expected to form stable secondary structures. Nature (1974) 1.21

An assessment of neural network and statistical approaches for prediction of E. coli promoter sites. Nucleic Acids Res (1992) 1.21

Cystoid macular edema in pseudophakia. Surv Ophthalmol (1984) 1.21

Structural principles that govern the peptide-binding motifs of class I MHC molecules. J Mol Biol (1998) 1.20

Solubilization and molecular characterization of membrane-bound antigens shared by thymocytes and brain. Eur J Immunol (1976) 1.18

T cell multideterminant regions in the human immunodeficiency virus envelope: toward overcoming the problem of major histocompatibility complex restriction. Int Immunol (1989) 1.17

Identification and cyclic AMP-induced modification of the cyclic AMP receptor in Dictyostelium discoideum. J Biol Chem (1985) 1.16

Prediction of protein structural class by discriminant analysis. Biochim Biophys Acta (1986) 1.15

Prediction of splice junctions in mRNA sequences. Nucleic Acids Res (1985) 1.14

Protein-protein recognition: exploring the energy funnels near the binding sites. Proteins (1999) 1.14

Analysis of the rate-limiting step in a ligand-cell receptor interaction: the immunoglobulin E system. Biochemistry (1983) 1.12

Fragment peptide library for classification and functional prediction of proteins. Proteins (1990) 1.12

Mechanism of binding of multivalent immune complexes to Fc receptors. 2. Kinetics of binding. Biochemistry (1981) 1.12

Bile salt metabolism in the human premature infant. Preliminary observations of pool size and synthesis rate following prenatal administration of dexamethasone and phenobarbital. Gastroenterology (1975) 1.11

Intraoperative monitoring of the recurrent laryngeal nerve in 151 consecutive patients undergoing thyroid surgery. Anesth Analg (2001) 1.11

Immunoglobulin E and eosinophilic cationic protein in segmental lavage fluid of the small and large bowel identify patients with food allergy. Am J Gastroenterol (2001) 1.09

Successful application of prenatal diagnosis in a pregnancy at risk for homozygous beta-thalassemia. N Engl J Med (1975) 1.09

Determining protein loop conformation using scaling-relaxation techniques. Protein Sci (1993) 1.08

[Ropivacaine for spinal anesthesia. A dose-finding study]. Anaesthesist (1996) 1.07

Multiple sequence alignment by parallel simulated annealing. Comput Appl Biosci (1993) 1.07

HOX homeobox genes exhibit spatial and temporal changes in expression during human skin development. J Invest Dermatol (1998) 1.07

A theory of measurement error and its implications for spatial and temporal gradient sensing during chemotaxis. Cell Biophys (1982) 1.07

Detection of weak sequence homology of proteins for tertiary structure prediction. Protein Seq Data Anal (1987) 1.05

Limitation in gamma probe localization of the sentinel node in breast cancer patients with large excisional biopsy. J Am Coll Surg (1999) 1.01

Computing the structure of bound peptides. Application to antigen recognition by class I major histocompatibility complex receptors. J Mol Biol (1993) 1.01

LIGAND database for enzymes, compounds and reactions. Nucleic Acids Res (1999) 1.01

The surface cyclic AMP receptor in Dictyostelium. Levels of ligand-induced phosphorylation, solubilization, identification of primary transcript, and developmental regulation of expression. J Biol Chem (1987) 1.01

[Intraoperative electromyographic recurrent laryngeal nerve identification as a routine measure]. Chirurg (2000) 1.01

Water-soluble poly-(L-glutamic acid)-Gly-camptothecin conjugates enhance camptothecin stability and efficacy in vivo. J Control Release (2001) 1.00