Secretion of lipoproteins from the liver of normal and Watanabe heritable hyperlipidemic rabbits.

PubWeight™: 1.16‹?› | Rank: Top 10%

🔗 View Article (PMC 534367)

Published in Proc Natl Acad Sci U S A on October 01, 1983

Authors

C A Hornick, T Kita, R L Hamilton, J P Kane, R J Havel

Articles citing this

The role of the LDL receptor in apolipoprotein B secretion. J Clin Invest (2000) 1.46

Metabolism of lipoproteins containing apolipoprotein B-100 in blood plasma of rabbits: heterogeneity related to the presence of apolipoprotein E. Proc Natl Acad Sci U S A (1986) 1.46

Endoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein B. Proc Natl Acad Sci U S A (2002) 1.35

Effect of low density lipoprotein receptor deficiency on the metabolism of apolipoprotein B-100 in blood plasma. Kinetic studies in normal and Watanabe heritable hyperlipidemic rabbits. J Clin Invest (1987) 1.34

JD induced pluripotent stem cell-derived hepatocytes faithfully recapitulate the pathophysiology of familial hypercholesterolemia. Hepatology (2012) 1.25

Metabolism of apolipoprotein B-100 in large very low density lipoproteins of blood plasma. Kinetic studies in normal and Watanabe heritable hyperlipidemic rabbits. J Clin Invest (1988) 1.24

Development of an integrated model for analysis of the kinetics of apolipoprotein B in plasma very low density lipoproteins, intermediate density lipoproteins, and low density lipoproteins. J Clin Invest (1985) 1.06

Regulatory effects of the saturated fatty acids 6:0 through 18:0 on hepatic low density lipoprotein receptor activity in the hamster. J Clin Invest (1992) 0.96

Fatty acids regulate hepatic low density lipoprotein receptor activity through redistribution of intracellular cholesterol pools. Proc Natl Acad Sci U S A (1992) 0.89

Lowering cholesterol, 1988. Rationale, mechanisms, and means. J Clin Invest (1988) 0.82

Increased hepatic lipase activity and increased direct removal of very-low-density lipoprotein remnants in Watanabe heritable hyperlipidaemic (WHHL) rabbits treated with ethinyl oestradiol. Biochem J (1990) 0.81

Inhibition of cholesterol synthesis reduces low-density-lipoprotein apoprotein B production without decreasing very-low-density-lipoprotein apoprotein B synthesis in rabbits. Biochem J (1984) 0.79

Alterations in the metabolism of very-low- and low-density lipoproteins after partial ileal-bypass surgery in the Watanabe heritable hyperlipidaemic rabbit. Biochem J (1991) 0.75

Articles cited by this

Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry (1965) 96.68

The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest (1955) 31.08

The estradiol-stimulated lipoprotein receptor of rat liver. A binding site that membrane mediates the uptake of rat lipoproteins containing apoproteins B and E. J Biol Chem (1980) 3.05

Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons. Proc Natl Acad Sci U S A (1980) 2.88

Delayed clearance of very low density and intermediate density lipoproteins with enhanced conversion to low density lipoprotein in WHHL rabbits. Proc Natl Acad Sci U S A (1982) 2.60

Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor. Proc Natl Acad Sci U S A (1982) 2.43

Discoidal bilayer structure of nascent high density lipoproteins from perfused rat liver. J Clin Invest (1976) 2.14

Deficiency of low density lipoprotein receptors in liver and adrenal gland of the WHHL rabbit, an animal model of familial hypercholesterolemia. Proc Natl Acad Sci U S A (1981) 2.08

Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia. Proc Natl Acad Sci U S A (1982) 1.98

The metabolism of the apoprotein of plasma low density lipoprotein in familial hyperbetalipoproteinaemia in the homozygous form. Atherosclerosis (1975) 1.95

Concentration and composition of lipoproteins in blood plasma of the WHHL rabbit. An animal model of human familial hypercholesterolemia. Arteriosclerosis (1983) 1.90

Characterization of human very low density lipoproteins containing two electrophoretic populations: double pre-beta lipoproteinemia and primary dysbetalipoproteinemia. J Lipid Res (1977) 1.80

A simple and inexpensive membrane "lung" for small organ perfusion. J Lipid Res (1974) 1.79

WHHL-rabbit: a low density lipoprotein receptor-deficient animal model for familial hypercholesterolemia. FEBS Lett (1980) 1.55

Radioimmunoassay of human arginine-rich apolipoprotein, apoprotein E. Concentration in blood plasma and lipoproteins as affected by apoprotein E-3 deficiency. J Clin Invest (1980) 1.54

Simultaneous measurement of apolipoprotein B turnover in very-low-and low-density lipoproteins in familial hypercholesterolaemia. Atherosclerosis (1977) 1.52

Cholestasis: lamellar structure of the abnormal human serum lipoprotein. Science (1971) 1.51

Cellular pathology of progressive atherosclerosis in the WHHL rabbit. An animal model of familial hypercholesterolemia. Arteriosclerosis (1983) 1.48

The LDL receptor locus and the genetics of familial hypercholesterolemia. Annu Rev Genet (1979) 1.46

Metabolism of apoprotein B of plasma very low density lipoproteins in the rat. J Clin Invest (1975) 1.36

Cholesterol synthesis in vivo and in vitro in the WHHL rabbit, an animal with defective low density lipoprotein receptors. J Lipid Res (1983) 1.12

Evidence that two synthetic pathways contribute to the apolipoprotein B pool of the low density lipoprotein fraction of rabbit plasma. Biochim Biophys Acta (1982) 1.01

Metabolism of esterified cholesterol in the plasma very low density lipoproteins of the rabbit. Atherosclerosis (1978) 0.93

Secretion of cholesterol-rich lipoproteins by perfused livers of hypercholesterolemic rats. J Clin Invest (1979) 0.92

Synthesis and release of low density lipoproteins by the isolated perfused pig liver. J Biol Chem (1977) 0.88

Secretion of nascent lipoproteins and apolipoproteins by perfused livers of normal and cholesterol-fed guinea pigs. J Lipid Res (1982) 0.88

Properties of lipoproteins in blood plasma and liver perfusates of rats with cholestasis. Gastroenterology (1982) 0.79

Articles by these authors

Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor. Nature (1979) 6.56

Prediction of acute left main coronary artery obstruction by 12-lead electrocardiography. ST segment elevation in lead aVR with less ST segment elevation in lead V(1). J Am Coll Cardiol (2001) 4.81

An endothelial receptor for oxidized low-density lipoprotein. Nature (1997) 3.76

Clinical characteristics of clear cell carcinoma of the ovary: a distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy. Cancer (2000) 3.46

Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia. Proc Natl Acad Sci U S A (1987) 3.32

The estradiol-stimulated lipoprotein receptor of rat liver. A binding site that membrane mediates the uptake of rat lipoproteins containing apoproteins B and E. J Biol Chem (1980) 3.05

Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons. Proc Natl Acad Sci U S A (1980) 2.88

Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens. JAMA (1990) 2.78

Quantum Hall effect in polar oxide heterostructures. Science (2007) 2.73

Lipid transport in liver. I. Electron microscopic identification of very low density lipoproteins in perfused rat liver. Lab Invest (1967) 2.72

Defective lipoprotein receptors and atherosclerosis. Lessons from an animal counterpart of familial hypercholesterolemia. N Engl J Med (1983) 2.67

Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL. J Clin Invest (1999) 2.66

Research evaluation and diagnosis of probable Alzheimer's disease over the last two decades: I. Neurology (2000) 2.64

Delayed clearance of very low density and intermediate density lipoproteins with enhanced conversion to low density lipoprotein in WHHL rabbits. Proc Natl Acad Sci U S A (1982) 2.60

Apolipoprotein L, a new human high density lipoprotein apolipoprotein expressed by the pancreas. Identification, cloning, characterization, and plasma distribution of apolipoprotein L. J Biol Chem (1997) 2.53

Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice. J Clin Invest (1999) 2.50

Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. J Exp Med (1994) 2.49

Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor. Proc Natl Acad Sci U S A (1982) 2.43

Pathogenesis, differentiation and management of hypertriglyceridemia. Adv Intern Med (1969) 2.40

Expression of SR-PSOX, a novel cell-surface scavenger receptor for phosphatidylserine and oxidized LDL in human atherosclerotic lesions. Arterioscler Thromb Vasc Biol (2001) 2.39

Apolipoprotein B: structural and metabolic heterogeneity. Annu Rev Physiol (1983) 2.33

Mouse macrophages synthesize and secrete a protein resembling apolipoprotein E. Proc Natl Acad Sci U S A (1981) 2.30

Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase. J Clin Invest (1980) 2.26

Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man. J Clin Invest (1973) 2.26

A rapid electrophoretic technique for identification of subunit species of apoproteins in serum lipoproteins. Anal Biochem (1973) 2.19

Apoprotein composition of very low density lipoproteins of human serum. J Clin Invest (1975) 2.18

Effects of a surfactant-associated protein and calcium ions on the structure and surface activity of lung surfactant lipids. Biochemistry (1985) 2.17

Splanchnic metabolism of free fatty acids and production of triglycerides of very low density lipoproteins in normotriglyceridemic and hypertriglyceridemic humans. J Clin Invest (1970) 2.17

Characterization of remnants produced during the metabolism of triglyceride-rich lipoproteins of blood plasma and intestinal lymph in the rat. J Clin Invest (1975) 2.15

Discoidal bilayer structure of nascent high density lipoproteins from perfused rat liver. J Clin Invest (1976) 2.14

A multilocus genotyping assay for candidate markers of cardiovascular disease risk. Genome Res (1999) 2.13

Inhibitory effects of C apolipoproteins from rats and humans on the uptake of triglyceride-rich lipoproteins and their remnants by the perfused rat liver. J Lipid Res (1985) 2.11

Regulation of the hepatic uptake of triglyceride-rich lipoproteins in the rat. Opposing effects of homologous apolipoprotein E and individual C apoproteins. J Biol Chem (1980) 2.09

Deficiency of low density lipoprotein receptors in liver and adrenal gland of the WHHL rabbit, an animal model of familial hypercholesterolemia. Proc Natl Acad Sci U S A (1981) 2.08

Characterization of subfractions of triglyceride-rich lipoproteins separated by gel chromatography from blood plasma of normolipemic and hyperlipemic humans. J Lipid Res (1972) 2.07

Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions. J Cell Biol (2001) 2.06

Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene. J Lipid Res (2001) 2.02

Proposed nomenclature of apoE isoproteins, apoE genotypes, and phenotypes. J Lipid Res (1982) 2.01

Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia. Proc Natl Acad Sci U S A (1982) 1.98

Hepatic metabolism of free fatty acids in normal and diabetic dogs. J Clin Invest (1970) 1.98

Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice. Nat Med (2000) 1.94

Concentration and composition of lipoproteins in blood plasma of the WHHL rabbit. An animal model of human familial hypercholesterolemia. Arteriosclerosis (1983) 1.90

Expression of lectinlike oxidized low-density lipoprotein receptor-1 in human atherosclerotic lesions. Circulation (1999) 1.88

Isolation of a cDNA clone encoding the amino-terminal region of human apolipoprotein B. Proc Natl Acad Sci U S A (1986) 1.86

Determinants of hepatic uptake of triglyceride-rich lipoproteins and their remnants in the rat. J Biol Chem (1980) 1.86

Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cells. Proc Natl Acad Sci U S A (1998) 1.84

Subcellular localization of B apoprotein of plasma lipoproteins in rat liver. J Cell Biol (1976) 1.81

X-34, a fluorescent derivative of Congo red: a novel histochemical stain for Alzheimer's disease pathology. J Histochem Cytochem (2000) 1.81

Isolation of a Golgi apparatus-rich fraction from rat liver. I. Method and morphology. J Cell Biol (1970) 1.80

Characterization of human very low density lipoproteins containing two electrophoretic populations: double pre-beta lipoproteinemia and primary dysbetalipoproteinemia. J Lipid Res (1977) 1.80

Expressions of PDGF receptor alpha, c-Kit and Flk1 genes clustering in mouse chromosome 5 define distinct subsets of nascent mesodermal cells. Dev Growth Differ (1997) 1.79

A simple and inexpensive membrane "lung" for small organ perfusion. J Lipid Res (1974) 1.79

Isoprotein specificity in the hepatic uptake of apolipoprotein E and the pathogenesis of familial dysbetalipoproteinemia. Proc Natl Acad Sci U S A (1980) 1.79

Familial dysbetalipoproteinemia. Abnormal binding of mutant apoprotein E to low density lipoprotein receptors of human fibroblasts and membranes from liver and adrenal of rats, rabbits, and cows. J Clin Invest (1981) 1.79

Hepatic catabolism of rat and human lipoproteins in rats treated with 17 alpha-ethinyl estradiol. J Biol Chem (1979) 1.78

Molecular cloning of a novel scavenger receptor for oxidized low density lipoprotein, SR-PSOX, on macrophages. J Biol Chem (2000) 1.76

Epidermal growth factor receptor expression and gene amplification in high-grade non-brainstem gliomas of childhood. Clin Cancer Res (1999) 1.76

Direct evidence of neuron impairment by oral infection with verotoxin-producing Escherichia coli O157:H- in mitomycin-treated mice. Infect Immun (1994) 1.72

Introduction to the plasma lipoproteins. Methods Enzymol (1986) 1.71

Cutting edge: combined treatment of TNF-alpha and IFN-gamma causes redistribution of junctional adhesion molecule in human endothelial cells. J Immunol (1999) 1.71

Cofactor activity of protein components of human very low density lipoproteins in the hydrolysis of triglycerides by lipoproteins lipase from different sources. Biochemistry (1973) 1.68

Sudden death from fulminant acute cerebellitis. Pediatr Neurosurg (2001) 1.68

The vast majority of gastric T cells are polarized to produce T helper 1 type cytokines upon antigenic stimulation despite the absence of Helicobacter pylori infection. J Gastroenterol (1999) 1.66

Primary dysbetalipoproteinemia: predominance of a specific apoprotein species in triglyceride-rich lipoproteins. Proc Natl Acad Sci U S A (1973) 1.66

Unilamellar liposomes made with the French pressure cell: a simple preparative and semiquantitative technique. J Lipid Res (1980) 1.64

Gains of 1q21-q22 and 13q12-q14 are potential indicators for resistance to cisplatin-based chemotherapy in ovarian cancer patients. Clin Cancer Res (1999) 1.60

Characterization of lipoprotein particles isolated from the Golgi apparatus of rat liver. J Lipid Res (1969) 1.59

SITES OF INITIAL REMOVAL OF CHYLOMICRON TRIGLYCERIDE FATTY ACIDS FROM THE BLOOD. J Clin Invest (1962) 1.58

Structural and metabolic heterogeneity of beta-very low density lipoproteins from cholesterol-fed dogs and from humans with type III hyperlipoproteinemia. J Lipid Res (1982) 1.57

Changes in lipid structure produced by surfactant proteins SP-A, SP-B, and SP-C. Am J Respir Cell Mol Biol (1991) 1.57

Research evaluation and diagnosis of possible Alzheimer's disease over the last two decades: II. Neurology (2000) 1.57

Attenuating effect of H+K+ATPase inhibitors on airway cough hypersensitivity induced by allergic airway inflammation in guinea-pigs. Clin Exp Allergy (2005) 1.56

Rationale and design of the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) study that evaluates atorvastatin in unstable angina pectoris and in non-Q-wave acute myocardial infarction. Am J Cardiol (1998) 1.55

Radioimmunoassay of human arginine-rich apolipoprotein, apoprotein E. Concentration in blood plasma and lipoproteins as affected by apoprotein E-3 deficiency. J Clin Invest (1980) 1.54

Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes. Proc Natl Acad Sci U S A (1998) 1.53

Bladder cancer and squamous metaplasia in spinal cord injury patients. J Urol (1977) 1.53

Role of specific glycopeptides of human serum lipoproteins in the activation of lipoprotein lipase. Circ Res (1970) 1.52

Multiple receptors for modified low density lipoproteins in mouse peritoneal macrophages: different uptake mechanisms for acetylated and oxidized low density lipoproteins. Biochem Biophys Res Commun (1989) 1.52

Autoradiographic localization of the sites of uptake, cellular transport, and catabolism of low density lipoproteins in the liver of normal and estrogen-treated rats. Proc Natl Acad Sci U S A (1981) 1.51

Cholestasis: lamellar structure of the abnormal human serum lipoprotein. Science (1971) 1.51

Normotriglyceridemic abetalipoproteinemia. absence of the B-100 apolipoprotein. J Clin Invest (1981) 1.50