Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions.

PubWeight™: 2.06‹?› | Rank: Top 2%

🔗 View Article (PMC 2196413)

Published in J Cell Biol on August 06, 2001

Authors

M Itoh1, H Sasaki, M Furuse, H Ozaki, T Kita, S Tsukita

Author Affiliations

1: 1Department of Cell Biology, Faculty of Medicine, Kyoto University, Kyoto 606-8501, Japan.

Articles citing this

Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice. J Cell Biol (2003) 5.74

Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex. J Cell Biol (2002) 2.18

Biology of claudins. Am J Physiol Renal Physiol (2008) 2.17

Tight junctions and the modulation of barrier function in disease. Histochem Cell Biol (2008) 2.13

Slit diaphragms contain tight junction proteins. J Am Soc Nephrol (2009) 2.08

The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex. J Cell Biol (2005) 2.03

aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells. Cell (2010) 1.94

Molecular basis of the core structure of tight junctions. Cold Spring Harb Perspect Biol (2010) 1.87

Dynamic behavior of paired claudin strands within apposing plasma membranes. Proc Natl Acad Sci U S A (2003) 1.66

Synapses: sites of cell recognition, adhesion, and functional specification. Annu Rev Biochem (2007) 1.65

Active participation of endothelial cells in inflammation. J Leukoc Biol (2005) 1.61

Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells. J Cell Biol (2002) 1.60

Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophils. Mol Biol Cell (2005) 1.57

Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis. Proc Natl Acad Sci U S A (2008) 1.53

Widely conserved signaling pathways in the establishment of cell polarity. Cold Spring Harb Perspect Biol (2009) 1.47

Barrier mechanisms in the developing brain. Front Pharmacol (2012) 1.45

Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation. Fluids Barriers CNS (2012) 1.44

Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem (2008) 1.43

Brain endothelial cell-cell junctions: how to "open" the blood brain barrier. Curr Neuropharmacol (2008) 1.38

A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cells. EMBO Rep (2006) 1.35

Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: similarities and differences. Fluids Barriers CNS (2011) 1.33

Organization of multiprotein complexes at cell-cell junctions. Histochem Cell Biol (2008) 1.33

JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1. Mol Cell Biol (2003) 1.28

Organization and signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees. Cell Tissue Res (2008) 1.26

Protein complexes that control renal epithelial polarity. Am J Physiol Renal Physiol (2011) 1.22

Architecture of tight junctions and principles of molecular composition. Semin Cell Dev Biol (2014) 1.21

Fractionation of the epithelial apical junctional complex: reassessment of protein distributions in different substructures. Mol Biol Cell (2004) 1.21

The organization of tight junctions in epithelia: implications for mammary gland biology and breast tumorigenesis. J Mammary Gland Biol Neoplasia (2003) 1.18

Cis-dimerization mediates function of junctional adhesion molecule A. Mol Biol Cell (2008) 1.17

Breaking into the epithelial apical-junctional complex--news from pathogen hackers. Curr Opin Cell Biol (2004) 1.15

Tight junction proteins: from barrier to tumorigenesis. Cancer Lett (2013) 1.14

The adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites. J Neurosci (2013) 1.11

Multiple protein interactions involving proposed extracellular loop domains of the tight junction protein occludin. Mol Biol Cell (2005) 1.07

aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation. J Cell Biol (2012) 1.07

Immunolocalization of tight junction proteins in the adult and developing human brain. Histochem Cell Biol (2004) 1.05

Reovirus preferentially infects the basolateral surface and is released from the apical surface of polarized human respiratory epithelial cells. J Infect Dis (2008) 1.02

Similar and distinct properties of MUPP1 and Patj, two homologous PDZ domain-containing tight-junction proteins. Mol Cell Biol (2009) 1.00

Similarities and differences in the regulation of leukocyte extravasation and vascular permeability. Semin Immunopathol (2014) 0.97

Structural determinants of Junctional Adhesion Molecule A (JAM-A) function and mechanisms of intracellular signaling. Curr Opin Cell Biol (2009) 0.96

Expression of JAM-A in the human corneal endothelium and retinal pigment epithelium: localization and evidence for role in barrier function. Invest Ophthalmol Vis Sci (2007) 0.95

JAM-related proteins in mucosal homeostasis and inflammation. Semin Immunopathol (2014) 0.93

Tight junctions in salivary epithelium. J Biomed Biotechnol (2010) 0.93

Signaling pathways in cell polarity. Cold Spring Harb Perspect Biol (2012) 0.92

Different domains of C. elegans PAR-3 are required at different times in development. Dev Biol (2010) 0.92

Deciphering the functional role of endothelial junctions by using in vivo models. EMBO Rep (2008) 0.92

"You Shall Not Pass"-tight junctions of the blood brain barrier. Front Neurosci (2014) 0.92

The interdependence of the Rho GTPases and apicobasal cell polarity. Small GTPases (2014) 0.91

Effects of JAM-A deficiency or blocking antibodies on neutrophil migration and lung injury in a murine model of ALI. Am J Physiol Lung Cell Mol Physiol (2012) 0.90

Tetraspanin CD9 links junctional adhesion molecule-A to αvβ3 integrin to mediate basic fibroblast growth factor-specific angiogenic signaling. Mol Biol Cell (2013) 0.90

Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-myosin II signaling. Proc Natl Acad Sci U S A (2012) 0.89

Enterocytes' tight junctions: From molecules to diseases. World J Gastrointest Pathophysiol (2011) 0.89

The Mammalian Blood-Testis Barrier: Its Biology and Regulation. Endocr Rev (2015) 0.88

The Wnt/planar cell polarity signaling pathway contributes to the integrity of tight junctions in brain endothelial cells. J Cereb Blood Flow Metab (2013) 0.87

Epithelial cell polarity and tumorigenesis: new perspectives for cancer detection and treatment. Acta Pharmacol Sin (2011) 0.87

Possible involvement of tight junctions, extracellular matrix and nuclear receptors in epithelial differentiation. J Biomed Biotechnol (2011) 0.87

Tight junctions: from simple barriers to multifunctional molecular gates. Nat Rev Mol Cell Biol (2016) 0.87

Regulation of blood-testis barrier (BTB) dynamics during spermatogenesis via the "Yin" and "Yang" effects of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2. Int Rev Cell Mol Biol (2013) 0.86

Loss of partitioning-defective-3/isotype-specific interacting protein (par-3/ASIP) in the elongating spermatid of RA175 (IGSF4A/SynCAM)-deficient mice. Am J Pathol (2007) 0.86

Relocalization of junctional adhesion molecule A during inflammatory stimulation of brain endothelial cells. Mol Cell Biol (2012) 0.86

The structure of the PDZ3-SH3-GuK tandem of ZO-1 protein suggests a supramodular organization of the membrane-associated guanylate kinase (MAGUK) family scaffold protein core. J Biol Chem (2011) 0.86

Microbial induction of vascular pathology in the CNS. J Neuroimmune Pharmacol (2010) 0.86

Establishment of epithelial polarity--GEF who's minding the GAP? J Cell Sci (2014) 0.84

Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells. Histochem Cell Biol (2008) 0.84

Critical role of tight junctions in drug delivery across epithelial and endothelial cell layers. J Membr Biol (2005) 0.82

Blood vessel epicardial substance (Bves) regulates epidermal tight junction integrity through atypical protein kinase C. J Biol Chem (2012) 0.82

Junctional adhesion molecule A promotes epithelial tight junction assembly to augment lung barrier function. Am J Pathol (2014) 0.81

Junctional proteins of the blood-brain barrier: New insights into function and dysfunction. Tissue Barriers (2016) 0.80

Inflammation and the Intestinal Barrier: Leukocyte-Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair. Gastroenterology (2016) 0.79

Mesenchymal stem cells with modification of junctional adhesion molecule a induce hair formation. Stem Cells Transl Med (2014) 0.78

Nectin-3 (CD113) interacts with Nectin-2 (CD112) to promote lymphocyte transendothelial migration. PLoS One (2013) 0.78

Emerging roles of Semaphorins in the regulation of epithelial and endothelial junctions. Tissue Barriers (2013) 0.78

Melatonin receptor expression in Xenopus laevis surface corneal epithelium: diurnal rhythm of lateral membrane localization. Mol Vis (2009) 0.78

Genomic organisation, embryonic expression and biochemical interactions of the zebrafish junctional adhesion molecule family of receptors. PLoS One (2012) 0.78

JAM-A is a novel surface marker for NG2-Glia in the adult mouse brain. BMC Neurosci (2010) 0.77

α1-Acid glycoprotein induced effects in rat brain microvessel endothelial cells. Microvasc Res (2012) 0.77

Beyond cell-cell adhesion: Emerging roles of the tight junction scaffold ZO-2. Tissue Barriers (2013) 0.77

Expression and distribution of junctional adhesion molecule-1 in the human cornea. Jpn J Ophthalmol (2007) 0.76

The role of JAM-B in cancer and cancer metastasis (Review). Oncol Rep (2016) 0.75

Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli. Cell Mol Gastroenterol Hepatol (2016) 0.75

Analysis of different components in the peritumoral tissue microenvironment of colorectal cancer: A potential prospect in tumorigenesis. Mol Med Rep (2016) 0.75

Tight junction modulation of the blood brain barrier: CNS delivery of small molecules. Tissue Barriers (2016) 0.75

The Par3 polarity protein is an exocyst receptor essential for mammary cell survival. Nat Commun (2017) 0.75

JAM-A and aPKC: A close pair during cell-cell contact maturation and tight junction formation in epithelial cells. Tissue Barriers (2013) 0.75

Articles cited by this

Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol (1993) 10.65

Multifunctional strands in tight junctions. Nat Rev Mol Cell Biol (2001) 9.62

Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J Cell Biol (1986) 8.74

Structure and function of intercellular junctions. Int Rev Cytol (1974) 8.14

Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol (1998) 7.78

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat Cell Biol (2000) 6.01

Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol (1998) 5.32

Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J Cell Biol (1999) 5.06

A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity. Nat Cell Biol (2000) 5.06

Identification of genes required for cytoplasmic localization in early C. elegans embryos. Cell (1988) 4.98

A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol (1998) 4.64

Tight junctions and the molecular basis for regulation of paracellular permeability. Am J Physiol (1995) 4.37

Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular junctional complexes. J Cell Sci (1995) 4.27

The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy. J Cell Biol (1993) 4.22

Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1. Proc Natl Acad Sci U S A (1991) 3.60

The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions. Proc Natl Acad Sci U S A (1993) 3.48

Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein. J Cell Biol (1994) 3.45

An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3. J Cell Biol (1998) 3.04

ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J Cell Biol (1998) 2.99

Human junction adhesion molecule regulates tight junction resealing in epithelia. J Cell Sci (2000) 2.97

Assembly of the tight junction: the role of diacylglycerol. J Cell Biol (1993) 2.61

Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures. J Cell Biol (2001) 2.51

Structural and signalling molecules come together at tight junctions. Curr Opin Cell Biol (1999) 2.16

Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin. J Biol Chem (2000) 2.13

PARsing embryonic polarity. Cell (2000) 2.08

A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCzeta signaling and cell transformation. Curr Biol (2000) 1.95

Cutting edge: combined treatment of TNF-alpha and IFN-gamma causes redistribution of junctional adhesion molecule in human endothelial cells. J Immunol (1999) 1.71

Molecular genetics of asymmetric cleavage in the early Caenorhabditis elegans embryo. Curr Opin Genet Dev (1996) 1.44

Homophilic interaction of junctional adhesion molecule. J Biol Chem (2000) 1.37

Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells. J Biol Chem (2000) 1.34

Identification and characterisation of human Junctional Adhesion Molecule (JAM). Mol Immunol (1999) 1.29

Articles by these authors

Functional annotation of a full-length mouse cDNA collection. Nature (2001) 23.61

Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol (1993) 10.65

Multifunctional strands in tight junctions. Nat Rev Mol Cell Biol (2001) 9.62

Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol (1998) 7.78

Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor. Nature (1979) 6.56

Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science (1995) 6.37

Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc Natl Acad Sci U S A (1999) 5.54

The Cognitive Abilities Screening Instrument (CASI): a practical test for cross-cultural epidemiological studies of dementia. Int Psychogeriatr (1994) 5.47

The 102 kd cadherin-associated protein: similarity to vinculin and posttranscriptional regulation of expression. Cell (1991) 5.27

Acquired growth hormone deficiency due to pituitary stalk transection after head trauma in childhood. Eur J Pediatr (1993) 5.16

Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. J Cell Biol (1998) 5.15

Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J Cell Biol (1999) 5.06

Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J Cell Biol (1994) 5.01

Prediction of acute left main coronary artery obstruction by 12-lead electrocardiography. ST segment elevation in lead aVR with less ST segment elevation in lead V(1). J Am Coll Cardiol (2001) 4.81

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras. Science (1993) 4.76

Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell (2000) 4.69

A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol (1998) 4.64

Calyculin A and okadaic acid: inhibitors of protein phosphatase activity. Biochem Biophys Res Commun (1989) 4.63

The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy. J Cell Biol (1993) 4.22

Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts. J Cell Biol (1992) 4.12

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons. J Cell Biol (1994) 4.09

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway. J Cell Biol (1996) 4.06

Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments. J Cell Biol (1997) 4.00

The dynamic behavior of the APC-binding protein EB1 on the distal ends of microtubules. Curr Biol (2000) 3.98

Preoperative portal embolization to increase safety of major hepatectomy for hilar bile duct carcinoma: a preliminary report. Surgery (1990) 3.93

Occludin is a functional component of the tight junction. J Cell Sci (1996) 3.90

Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells. J Cell Biol (1999) 3.78

An endothelial receptor for oxidized low-density lipoprotein. Nature (1997) 3.76

Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells. J Cell Biol (2001) 3.66

Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J Cell Biol (1998) 3.62

Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions. Curr Opin Cell Biol (1992) 3.61

Manner of interaction of heterogeneous claudin species within and between tight junction strands. J Cell Biol (1999) 3.57

Interaction of spinach leaf adenosine diphosphate glucose alpha-1,4-glucan alpha-4-glucosyl transferase and alpha-1,4-glucan, alpha-1,4-glucan-6-glycosyl transferase in synthesis of branched alpha-glucan. Arch Biochem Biophys (1974) 3.55

Clinical characteristics of clear cell carcinoma of the ovary: a distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy. Cancer (2000) 3.46

Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line. J Cell Biol (1994) 3.43

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2. J Cell Biol (1998) 3.39

Magnifying endoscopy combined with narrow band imaging system for early gastric cancer: correlation of vascular pattern with histopathology (including video). Endoscopy (2004) 3.36

Possible involvement of phosphorylation of occludin in tight junction formation. J Cell Biol (1997) 3.35

Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia. Proc Natl Acad Sci U S A (1987) 3.32

The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules. J Cell Biol (1994) 3.31

A 220-kD undercoat-constitutive protein: its specific localization at cadherin-based cell-cell adhesion sites. J Cell Biol (1991) 3.31

Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells. J Cell Sci (1995) 3.27

Real-time imaging of cell-cell adherens junctions reveals that Drosophila mesoderm invagination begins with two phases of apical constriction of cells. J Cell Sci (2001) 3.25

The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane. Trends Biochem Sci (1998) 3.24

Occludin and claudins in tight-junction strands: leading or supporting players? Trends Cell Biol (1999) 3.23

Cytoplasmic regulation of the movement of E-cadherin on the free cell surface as studied by optical tweezers and single particle tracking: corralling and tethering by the membrane skeleton. J Cell Biol (1998) 3.23

Calcium movements, distribution, and functions in smooth muscle. Pharmacol Rev (1997) 3.23

Regulation of imprinted X-chromosome inactivation in mice by Tsix. Development (2001) 3.12

Parental-origin-specific epigenetic modification of the mouse H19 gene. Nature (1993) 3.11

The movement of membranous organelles in axons. Electron microscopic identification of anterogradely and retrogradely transported organelles. J Cell Biol (1980) 3.08

Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein. J Biol Chem (1997) 3.08

Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique, DIRECT. Nat Genet (1996) 3.07

Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia. Blood (2001) 3.07

Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. Am J Hum Genet (2000) 3.06

A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites. J Cell Sci (1992) 3.04

Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier. J Cell Biol (1999) 3.02

Occludin as a possible determinant of tight junction permeability in endothelial cells. J Cell Sci (1997) 2.97

Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. J Cell Biol (1996) 2.94

Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members. J Cell Biol (1994) 2.93

Cadherin dysfunction in a human cancer cell line: possible involvement of loss of alpha-catenin expression in reduced cell-cell adhesiveness. Cancer Res (1992) 2.89

Vagally mediated heart rate recovery after exercise is accelerated in athletes but blunted in patients with chronic heart failure. J Am Coll Cardiol (1994) 2.89

Submembranous junctional plaque proteins include potential tumor suppressor molecules. J Cell Biol (1993) 2.87

A new 82-kD barbed end-capping protein (radixin) localized in the cell-to-cell adherens junction: purification and characterization. J Cell Biol (1989) 2.84

Basal cell carcinomas in mice overexpressing Gli2 in skin. Nat Genet (2000) 2.82

Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junction. J Cell Biol (1997) 2.82

Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell (1995) 2.81

Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M. Nat Genet (1996) 2.77

Continuing evolution of H9N2 influenza viruses in Southeastern China. J Virol (2004) 2.75

Quantum Hall effect in polar oxide heterostructures. Science (2007) 2.73

Transgenic mice with increased expression of vascular endothelial growth factor in the retina: a new model of intraretinal and subretinal neovascularization. Am J Pathol (1997) 2.73

Amantadine and pneumonia. Lancet (1999) 2.69

Defective lipoprotein receptors and atherosclerosis. Lessons from an animal counterpart of familial hypercholesterolemia. N Engl J Med (1983) 2.67

Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development (1998) 2.67

Pores in the wall: claudins constitute tight junction strands containing aqueous pores. J Cell Biol (2000) 2.62