Published in Proc Natl Acad Sci U S A on July 01, 1984
Cloning and characterization of cDNAs encoding 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible rabbit mRNAs for cytochrome P-450 isozymes 4 and 6. Proc Natl Acad Sci U S A (1985) 1.08
Identification of human cytochromes P-450 analogous to forms induced by phenobarbital and 3-methylcholanthrene in the rat. Biochem J (1985) 1.03
Human cytochrome P-450 4 mRNA and gene: part of a multigene family that contains Alu sequences in its mRNA. Proc Natl Acad Sci U S A (1986) 0.96
Inter-relatedness of some isoenzymes of cytochrome P-450 from rat, rabbit and human, determined with monoclonal antibodies. Biochem J (1986) 0.87
Interspecies conservation of structure of interphotoreceptor retinoid-binding protein. Similarities and differences as adjudged by peptide mapping and N-terminal sequencing. Biochem J (1986) 0.79
Tissue sulfhydryl groups. Arch Biochem Biophys (1959) 61.89
Mechanisms for the incorporation of proteins in membranes and organelles. J Cell Biol (1982) 9.67
The chromatographic determination of cystine and cysteine residues in proteins as s-beta-(4-pyridylethyl)cysteine. J Biol Chem (1970) 2.59
Improved manual sequencing methods. Methods Enzymol (1977) 2.34
Primary structure of a cytochrome P-450: coding nucleotide sequence of phenobarbital-inducible cytochrome P-450 cDNA from rat liver. Proc Natl Acad Sci U S A (1982) 2.19
Cleavage at glutamic acid with staphylococcal protease. Methods Enzymol (1977) 2.03
Purification and characterization of a unique isozyme of cytochrome P-450 from liver microsomes of ethanol-treated rabbits. J Biol Chem (1982) 1.71
Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450. J Biol Chem (1976) 1.50
Identification and localization of amino acid substitutions between two phenobarbital-inducible rat hepatic microsomal cytochromes P-450 by micro sequence analyses. Proc Natl Acad Sci U S A (1983) 1.43
Amino acid sequence of an analogous peptide from two forms of cytochrome P-450. J Biol Chem (1981) 1.43
Purified liver microsomal cytochrome P-450. Separation and characterization of multiple forms. J Biol Chem (1975) 1.39
Reverse-phase high-performance liquid chromatography of hydrophobic proteins and fragments thereof. Anal Biochem (1983) 1.31
Complete amino acid sequence and predicted membrane topology of phenobarbital-induced cytochrome P-450 (isozyme 2) from rabbit liver microsomes. Proc Natl Acad Sci U S A (1983) 1.30
Steroid 21-hydroxylase (cytochrome P-450) from porcine adrenocortical microsomes: microsequence analysis of cysteine-containing peptides. Biochemistry (1983) 1.23
The complete amino acid sequence of rabbit phenobarbital-induced liver microsomal cytochrome P-450. J Biol Chem (1983) 1.18
Coding nucleotide sequence of 3-methylcholanthrene-inducible cytochrome P-450d cDNA from rat liver. Proc Natl Acad Sci U S A (1984) 1.14
Hepatic microsomal cytochrome P-450 from rats treated with isosafrole. Purification and characterization of four enzymic forms. J Biol Chem (1980) 1.13
Amino-terminal and carboxy-terminal sequence of hepatic microsomal cytochrome P-450d, a unique hemoprotein from rats treated with isosafrole. Biochemistry (1982) 1.09
Amino acid sequence of the Pseudomonas putida cytochrome P-450. II. Cyanogen bromide peptides, acid cleavage peptides, and the complete sequence. J Biol Chem (1982) 1.07
Amino-terminal sequence of phenobarbital-inducible cytochrome P-450 from rabbit liver microsomes: similarity to hydrophobic amino-terminal segments of preproteins. Biochem Biophys Res Commun (1977) 1.03
Simple, rapid, and highly efficient separation of amino acid phenylthiohydantoins by reversed-phase high-performance liquid chromatography. Anal Biochem (1982) 1.02
Structural features of isozyme 2 of liver microsomal cytochrome P-450. Identification of a highly conserved cysteine-containing peptide. J Biol Chem (1982) 0.97
Selective cleavage of the single tryptophanyl peptide bond in horse heart cytochrome c. FEBS Lett (1973) 0.94
The covalent structure of rabbit phenobarbital-induced cytochrome P-450. Partial amino acid sequence and order of cyanogen bromide peptides. J Biol Chem (1982) 0.87
Specific O-acylation of hydroxylamino acids in presence of free amino groups. Biochim Biophys Acta (1972) 0.80
A comparison of fluorescamine and o-phthaldialdehyde as effective blocking reagents in protein sequence analyses by the Beckman sequencer. Anal Biochem (1983) 0.80
Role of isosafrole as complexing agent and inducer of P-450LM4 in rabbit liver microsomes. Biochem Biophys Res Commun (1982) 0.79
Isolation, purification, and properties of a unique form of cytochrome P-450 in microsomes of isosafrole-treated rats. J Biol Chem (1981) 0.77
P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics (1996) 6.12
The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. DNA Cell Biol (1993) 4.92
Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains. Nature (1990) 4.70
The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature. DNA Cell Biol (1991) 3.73
Polyquarternary amines prevent peptide loss from sequenators. Anal Biochem (1978) 3.61
Oxygen activation by cytochrome P-450. Annu Rev Biochem (1980) 3.44
The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci. DNA (1989) 3.03
Inactivation of key metabolic enzymes by mixed-function oxidation reactions: possible implication in protein turnover and ageing. Proc Natl Acad Sci U S A (1983) 2.98
The P450 gene superfamily: recommended nomenclature. DNA (1987) 2.95
Enzymatic omega-oxidation. IV. Purification and properties of the omega-hydroxylase of Pseudomonas oleovorans. J Biol Chem (1970) 2.89
Enzymatic omega-oxidation. I. Electon carriers in fatty acid and hydrocarbon hydroxylation. J Biol Chem (1966) 2.83
Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms. J Biol Chem (1991) 2.68
Enzymatic omega-oxidation. II. Function of rubredoxin as the electron carrier in omega-hydroxylation. J Biol Chem (1967) 2.62
Effect of superoxide generation and dismutation on hydroxylation reactions catalyzed by liver microsomal cytochrome P-450. J Biol Chem (1971) 2.35
Improved manual sequencing methods. Methods Enzymol (1977) 2.34
Role of hemoprotein P-450 in fatty acid omega-hydroxylation in a soluble enzyme system from liver microsomes. J Biol Chem (1968) 1.92
Resolution of the cytochrome P-450-containing omega-hydroxylation system of liver microsomes into three components. J Biol Chem (1969) 1.84
Phosphatidylcholine requirement in the enzymatic reduction of hemoprotein P-450 and in fatty acid, hydrocarbon, and drug hydroxylation. J Biol Chem (1970) 1.76
Purification and characterization of a unique isozyme of cytochrome P-450 from liver microsomes of ethanol-treated rabbits. J Biol Chem (1982) 1.71
Preparation and properties of partially purified cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase from rabbit liver microsomes. J Biol Chem (1974) 1.69
Purified liver microsomal NADPH-cytochrome P-450 reductase. Spectral characterization of oxidation-reduction states. J Biol Chem (1978) 1.68
Attenuation of CCl(4)-induced hepatic fibrosis by GdCl(3) treatment or dietary glycine. Am J Physiol Gastrointest Liver Physiol (2001) 1.64
Purification, physicochemical, and kinetic properties of liver acetyl-CoA:arylamine N-acetyltransferase from rapid acetylator rabbits. Mol Pharmacol (1987) 1.60
Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a. Mol Pharmacol (1986) 1.58
Enzymatic omega-oxidation. 3. Purification and properties of rubredoxin, a component of the omega-hydroxylation system of Pseudomonas oleovorans. J Biol Chem (1968) 1.56
Separate roles for FMN and FAD in catalysis by liver microsomal NADPH-cytochrome P-450 reductase. J Biol Chem (1981) 1.56
Studies on hydroperoxide-dependent substrate hydroxylation by purified liver microsomal cytochrome P-450. Arch Biochem Biophys (1976) 1.54
On the stoichiometry of the oxidase and monooxygenase reactions catalyzed by liver microsomal cytochrome P-450. Products of oxygen reduction. J Biol Chem (1984) 1.52
Purification and characterization of the Rieske iron-sulfur protein from Thermus thermophilus. Evidence for a [2Fe-2S] cluster having non-cysteine ligands. J Biol Chem (1984) 1.51
Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450. J Biol Chem (1976) 1.50
CD10/neutral endopeptidase 24.11 hydrolyzes bombesin-like peptides and regulates the growth of small cell carcinomas of the lung. Proc Natl Acad Sci U S A (1991) 1.47
Structural features of liver microsomal NADPH-cytochrome P-450 reductase. Hydrophobic domain, hydrophilic domain, and connecting region. J Biol Chem (1982) 1.45
Effects of the wine polyphenolics quercetin and resveratrol on pro-inflammatory cytokine expression in RAW 264.7 macrophages. Biochem Pharmacol (1999) 1.44
Molecular cloning of the CD3 eta subunit identifies a CD3 zeta-related product in thymus-derived cells. Proc Natl Acad Sci U S A (1990) 1.44
Two forms of liver microsomal cytochrome P-450, P-450lm2 and P-450LM4 (rabbit liver). Methods Enzymol (1978) 1.42
Interactions of cytochrome P-450, NADPH-cytochrome P-450 reductase, phospholipid, and substrate in the reconstituted liver microsomal enzyme system. J Biol Chem (1980) 1.40
Epoxidation of olefins by cytochrome P450: evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidant. Proc Natl Acad Sci U S A (1998) 1.40
Human hypoxanthine (guanine) phosphoribosyltransferase: an amino acid substitution in a mutant form of the enzyme isolated from a patient with gout. Proc Natl Acad Sci U S A (1983) 1.39
Purified liver microsomal cytochrome P-450. Separation and characterization of multiple forms. J Biol Chem (1975) 1.39
Peroxo-iron and oxenoid-iron species as alternative oxygenating agents in cytochrome P450-catalyzed reactions: switching by threonine-302 to alanine mutagenesis of cytochrome P450 2B4. Proc Natl Acad Sci U S A (1996) 1.39
Stereospecificity and other properties of highly purified beta-hydroxy-beta-methylglutaryl coenzyme A cleavage enzyme from bovine liver. J Biol Chem (1968) 1.36
Identification of the omega-hydroxylase of Pseudomonas oleovorans as a nonheme iron protein requiring phospholipid for catalytic activity. Biochem Biophys Res Commun (1974) 1.35
Identification of the high and low potential flavins of liver microsomal NADPH-cytochrome P-450 reductase. J Biol Chem (1978) 1.35
Human hypoxanthine-guanine phosphoribosyltransferase. Complete amino acid sequence of the erythrocyte enzyme. J Biol Chem (1982) 1.33
Reverse-phase high-performance liquid chromatography of hydrophobic proteins and fragments thereof. Anal Biochem (1983) 1.31
Complete amino acid sequence and predicted membrane topology of phenobarbital-induced cytochrome P-450 (isozyme 2) from rabbit liver microsomes. Proc Natl Acad Sci U S A (1983) 1.30
Enzymatic omega-oxidation. V. Forms of Pseudomonas oleovorans rubredoxin containing one or two iron atoms: structure and function in omega-hydroxylation. J Biol Chem (1971) 1.30
Subunit structure of rabbit muscle pyruvate kinase. J Biol Chem (1969) 1.29
CYP2E1 is not involved in early alcohol-induced liver injury. Am J Physiol (1999) 1.29
Properties of NADPH-cytochrome P-450 reductase purified from rabbit liver microsomes. Arch Biochem Biophys (1979) 1.25
Role of cytochrome P-450 2E1 in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidation. Hepatology (1992) 1.22
Induction of multiple forms of mouse liver cytochrome P-450. Evidence for genetically controlled de novo protein synthesis in response to treatment with beta-naphthoflavone or phenobarbital. J Biol Chem (1976) 1.19
A general procedure for the manual sequencing of small quantities of peptides. Anal Biochem (1975) 1.19
An analysis of the electron paramagnetic resonance spectrum of pseudomonas oleovorans rubredoxin. A method for determination of the liganids of ferric iron in completely rhombic sites. J Biol Chem (1971) 1.17
P-450 cytochromes: structure and function. Adv Enzymol Relat Areas Mol Biol (1987) 1.16
Role of a hydrophobic polypeptide in the N-terminal region of NADPH-cytochrome P-450 reductase in complex formation with P-450LM. Biochem Biophys Res Commun (1979) 1.15
Enzymatic oxidation. VII. Reduced diphosphopyridine nucleotide-rubredoxin reductase: properties and function as an electron carrier in hydroxylation. J Biol Chem (1972) 1.15
Crystal structure of the conserved subdomain of human protein SRP54M at 2.1 A resolution: evidence for the mechanism of signal peptide binding. J Mol Biol (1999) 1.12
Hydrogen peroxide formation and stoichiometry of hydroxylation reactions catalyzed by highly purified liver microsomal cytochrome P-450. Arch Biochem Biophys (1977) 1.11
Immunochemical characterization of multiple forms of cytochrome P-450 in rabbit nasal microsomes and evidence for tissue-specific expression of P-450s NMa and NMb. Mol Pharmacol (1990) 1.11
Catalysis by cytochrome P-450 of an oxidative reaction in xenobiotic aldehyde metabolism: deformylation with olefin formation. Proc Natl Acad Sci U S A (1991) 1.11
Oxidation-reduction states of FMN and FAD in NADPH-cytochrome P-450 reductase during reduction by NADPH. J Biol Chem (1982) 1.09
Regio- and stereoselective epoxidation of arachidonic acid by human cytochromes P450 2C8 and 2C9. J Pharmacol Exp Ther (1994) 1.08
Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P-450 of rabbit liver microsomes by diverse agents: ethanol, imidazole, trichloroethylene, acetone, pyrazole, and isoniazid. Proc Natl Acad Sci U S A (1985) 1.08
Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-alpha. Biochem Pharmacol (2001) 1.08
Alcohol-inducible cytochrome P-450IIE1 lacking the hydrophobic NH2-terminal segment retains catalytic activity and is membrane-bound when expressed in Escherichia coli. J Biol Chem (1991) 1.07
Characterization of the omega-hydroxylase of Pseudomonas oleovorans as a nonheme iron protein. Arch Biochem Biophys (1977) 1.06
C-terminal ladder sequencing via matrix-assisted laser desorption mass spectrometry coupled with carboxypeptidase Y time-dependent and concentration-dependent digestions. Anal Chem (1995) 1.06
Identification of ethanol-inducible P-450 isozyme 3a as the acetone and acetol monooxygenase of rabbit microsomes. J Biol Chem (1985) 1.05
Highly purified detergent-solubilized NADPH-cytochrome P-450 reductase from phenobarbital-induced rat liver microsomes. Biochem Biophys Res Commun (1974) 1.05
Role of lysyl epsilon-amino groups in adenosine diphosphate binding and catalytic activity of pyruvate kinase. J Biol Chem (1971) 1.05
Properties of a solubilized form of the cytochrome P-450-containing mixed-function oxidase of liver microsomes. Mol Pharmacol (1970) 1.05
Membrane topology of mammalian cytochromes P-450 from liver endoplasmic reticulum. Determination by trypsinolysis of phenobarbital-treated microsomes. J Biol Chem (1989) 1.05
Reduction of alkyl hydroperoxides to alcohols: role of rubredoxin, an electron carrier in the bacterial hydroxylation of hydrocarbons. Biochem Biophys Res Commun (1971) 1.04
Catalytic activity of cytochrome P-450 isozyme 3a isolated from liver microsomes of ethanol-treated rabbits. Oxidation of alcohols. J Biol Chem (1982) 1.03
Amino-terminal sequence of phenobarbital-inducible cytochrome P-450 from rabbit liver microsomes: similarity to hydrophobic amino-terminal segments of preproteins. Biochem Biophys Res Commun (1977) 1.03
Degradation of cytochrome P450 2E1: selective loss after labilization of the enzyme. Arch Biochem Biophys (1992) 1.03
Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1. J Biol Chem (1993) 1.02
Simple, rapid, and highly efficient separation of amino acid phenylthiohydantoins by reversed-phase high-performance liquid chromatography. Anal Biochem (1982) 1.02
Fatty acid and hydrocarbon hydroxylation in yeast: role of cytochrome P-450 in Candida tropicalis. Biochem Biophys Res Commun (1971) 1.02
Structural resemblance of cytochrome P-450 isolated from Pseudomonas putida and from rabbit liver microsomes. Biochem Biophys Res Commun (1974) 1.01
Mechanism of action of pyruvate kinase. Role of sulfhydryl groups in catalytic activity as determined by disulfide interchange. J Biol Chem (1972) 1.01
Isolation of a cDNA coding for human galactosyltransferase. Biochem Biophys Res Commun (1986) 1.01
Effects of cytochrome b5 on cytochrome P-450-catalyzed reactions. Studies with manganese-substituted cytochrome b5. Drug Metab Dispos (1984) 1.01
Properties of a yeast cytochrome P-450-containing enzyme system which catalyzes the hydroxylation of fatty acids, alkanes, and drugs. Eur J Biochem (1973) 1.01
Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding. Biochemistry (1999) 1.01
Cooperative assembly of signal recognition particle RNA with protein SRP19. Biochemistry (1995) 0.99
Rapid separation of amino acid phenylthiohydantoins by isocratic high-performance liquid chromatography. Anal Biochem (1981) 0.98