Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Prediction of the occurrence of the ADP-binding beta alpha beta-fold in proteins, using an amino acid sequence fingerprint.
|
J Mol Biol
|
1986
|
9.13
|
2
|
The alpha-helix dipole and the properties of proteins.
|
Nature
|
1978
|
4.59
|
3
|
Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA.
|
Science
|
1998
|
4.51
|
4
|
Crystal structure of a cholera toxin-related heat-labile enterotoxin from E. coli.
|
Nature
|
1991
|
4.11
|
5
|
A model for the mechanism of human topoisomerase I.
|
Science
|
1998
|
4.10
|
6
|
Predicted nucleotide-binding properties of p21 protein and its cancer-associated variant.
|
Nature
|
1983
|
3.94
|
7
|
The role of the alpha-helix dipole in protein function and structure.
|
Prog Biophys Mol Biol
|
1985
|
3.42
|
8
|
Crystal structure of cholera toxin B-pentamer bound to receptor GM1 pentasaccharide.
|
Protein Sci
|
1994
|
3.19
|
9
|
Dipoles of the alpha-helix and beta-sheet: their role in protein folding.
|
Nature
|
1981
|
2.56
|
10
|
Synergistic effects of substrate-induced conformational changes in phosphoglycerate kinase activation.
|
Nature
|
1997
|
2.23
|
11
|
Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxin.
|
J Mol Biol
|
1993
|
2.17
|
12
|
Lactose binding to heat-labile enterotoxin revealed by X-ray crystallography.
|
Nature
|
1992
|
2.08
|
13
|
Structure of the heat shock protein chaperonin-10 of Mycobacterium leprae.
|
Science
|
1996
|
2.03
|
14
|
Difference density quality (DDQ): a method to assess the global and local correctness of macromolecular crystal structures.
|
Acta Crystallogr D Biol Crystallogr
|
1999
|
2.01
|
15
|
Dihydrofolate reductase from Lactobacillus casei. X-ray structure of the enzyme methotrexate.NADPH complex.
|
J Biol Chem
|
1978
|
1.94
|
16
|
Computer simulation of the dynamics of hydrated protein crystals and its comparison with x-ray data.
|
Proc Natl Acad Sci U S A
|
1983
|
1.69
|
17
|
Structure of bovine liver rhodanese. I. Structure determination at 2.5 A resolution and a comparison of the conformation and sequence of its two domains.
|
J Mol Biol
|
1978
|
1.67
|
18
|
The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions.
|
Nat Struct Biol
|
1994
|
1.63
|
19
|
Crystal structure of hexameric haemocyanin from Panulirus interruptus refined at 3.2 A resolution.
|
J Mol Biol
|
1989
|
1.63
|
20
|
Crystallographic analysis of oxygenated and deoxygenated states of arthropod hemocyanin shows unusual differences.
|
Proteins
|
1994
|
1.58
|
21
|
Crystal structure of p-hydroxybenzoate hydroxylase.
|
J Mol Biol
|
1979
|
1.53
|
22
|
Three-dimensional structure of the diphtheria toxin repressor in complex with divalent cation co-repressors.
|
Structure
|
1995
|
1.53
|
23
|
Refined 1.83 A structure of trypanosomal triosephosphate isomerase crystallized in the presence of 2.4 M-ammonium sulphate. A comparison with the structure of the trypanosomal triosephosphate isomerase-glycerol-3-phosphate complex.
|
J Mol Biol
|
1991
|
1.50
|
24
|
High-resolution structure of the diphtheria toxin repressor complexed with cobalt and manganese reveals an SH3-like third domain and suggests a possible role of phosphate as co-corepressor.
|
Biochemistry
|
1996
|
1.47
|
25
|
Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain.
|
J Mol Biol
|
1999
|
1.46
|
26
|
Glycolysis as a target for the design of new anti-trypanosome drugs.
|
Drug Resist Updat
|
2001
|
1.45
|
27
|
Crystal structure of the p-hydroxybenzoate hydroxylase-substrate complex refined at 1.9 A resolution. Analysis of the enzyme-substrate and enzyme-product complexes.
|
J Mol Biol
|
1989
|
1.44
|
28
|
Structure of bovine pancreatic phospholipase A2 at 1.7A resolution.
|
J Mol Biol
|
1981
|
1.44
|
29
|
Atomic structure of the cubic core of the pyruvate dehydrogenase multienzyme complex.
|
Science
|
1992
|
1.44
|
30
|
Galactose-binding site in Escherichia coli heat-labile enterotoxin (LT) and cholera toxin (CT).
|
Mol Microbiol
|
1994
|
1.43
|
31
|
Crystal structure of a new heat-labile enterotoxin, LT-IIb.
|
Structure
|
1996
|
1.42
|
32
|
Crystal structure of deoxygenated Limulus polyphemus subunit II hemocyanin at 2.18 A resolution: clues for a mechanism for allosteric regulation.
|
Protein Sci
|
1993
|
1.41
|
33
|
The covalent and tertiary structure of bovine liver rhodanese.
|
Nature
|
1978
|
1.41
|
34
|
The 2.0 A crystal structure of cephalosporin acylase.
|
Structure
|
2000
|
1.37
|
35
|
Molecular dynamics refinement of a thermitase-eglin-c complex at 1.98 A resolution and comparison of two crystal forms that differ in calcium content.
|
J Mol Biol
|
1989
|
1.34
|
36
|
A rapid method for positioning small flexible molecules, nucleic acids, and large protein fragments in experimental electron density maps.
|
Proteins
|
1999
|
1.33
|
37
|
Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action.
|
J Mol Biol
|
2000
|
1.32
|
38
|
Crystal structure of the iron-dependent regulator (IdeR) from Mycobacterium tuberculosis shows both metal binding sites fully occupied.
|
J Mol Biol
|
1999
|
1.32
|
39
|
Overcoming codon bias: a method for high-level overexpression of Plasmodium and other AT-rich parasite genes in Escherichia coli.
|
Int J Parasitol
|
2000
|
1.32
|
40
|
Principles of quasi-equivalence and Euclidean geometry govern the assembly of cubic and dodecahedral cores of pyruvate dehydrogenase complexes.
|
Proc Natl Acad Sci U S A
|
1999
|
1.31
|
41
|
Refined crystal structure of lipoamide dehydrogenase from Azotobacter vinelandii at 2.2 A resolution. A comparison with the structure of glutathione reductase.
|
J Mol Biol
|
1991
|
1.27
|
42
|
Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs.
|
J Mol Biol
|
2000
|
1.27
|
43
|
Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA.
|
Biochemistry
|
2000
|
1.27
|
44
|
AB5 toxins.
|
Curr Opin Struct Biol
|
1995
|
1.26
|
45
|
A flash-annealing technique to improve diffraction limits and lower mosaicity in crystals of glycerol kinase.
|
Acta Crystallogr D Biol Crystallogr
|
1998
|
1.26
|
46
|
Structure of quinoprotein methylamine dehydrogenase at 2.25 A resolution.
|
EMBO J
|
1989
|
1.25
|
47
|
Structural flexibility in human topoisomerase I revealed in multiple non-isomorphous crystal structures.
|
J Mol Biol
|
1999
|
1.24
|
48
|
The 1.25 A resolution refinement of the cholera toxin B-pentamer: evidence of peptide backbone strain at the receptor-binding site.
|
J Mol Biol
|
1998
|
1.24
|
49
|
Crystal structure of recombinant human triosephosphate isomerase at 2.8 A resolution. Triosephosphate isomerase-related human genetic disorders and comparison with the trypanosomal enzyme.
|
Protein Sci
|
1994
|
1.23
|
50
|
Effects of the alpha-helix dipole upon the functioning and structure of proteins and peptides.
|
Adv Biophys
|
1985
|
1.23
|
51
|
Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase.
|
Structure
|
1996
|
1.22
|
52
|
Comparison of the hemocyanin beta-barrel with other Greek key beta-barrels: possible importance of the "beta-zipper" in protein structure and folding.
|
Proteins
|
1992
|
1.21
|
53
|
A comparison of the three-dimensional structures of subtilisin BPN' and subtilisin novo.
|
Cold Spring Harb Symp Quant Biol
|
1972
|
1.21
|
54
|
Inclusion of thermal motion in crystallographic structures by restrained molecular dynamics.
|
Science
|
1990
|
1.20
|
55
|
AB(5) toxins: structures and inhibitor design.
|
Curr Opin Struct Biol
|
2000
|
1.19
|
56
|
The refined crystal structure of Pseudomonas putida lipoamide dehydrogenase complexed with NAD+ at 2.45 A resolution.
|
Proteins
|
1992
|
1.19
|
57
|
Crystal structure of 2-oxoisovalerate and dehydrogenase and the architecture of 2-oxo acid dehydrogenase multienzyme complexes.
|
Nat Struct Biol
|
1999
|
1.18
|
58
|
The crystal structure of the "open" and the "closed" conformation of the flexible loop of trypanosomal triosephosphate isomerase.
|
Proteins
|
1991
|
1.17
|
59
|
Structure of porcine pancreatic phospholipase A2 at 2.6 A resolution and comparison with bovine phospholipase A2.
|
J Mol Biol
|
1983
|
1.16
|
60
|
Crystal structure of the iron-dependent regulator from Mycobacterium tuberculosis at 2.0-A resolution reveals the Src homology domain 3-like fold and metal binding function of the third domain.
|
J Biol Chem
|
2000
|
1.15
|
61
|
A very fast program for visualizing protein surfaces, channels and cavities.
|
J Mol Graph
|
1989
|
1.14
|
62
|
Structural insights into the function of type IB topoisomerases.
|
Curr Opin Struct Biol
|
1999
|
1.13
|
63
|
Structure-based drug design: progress, results and challenges.
|
Structure
|
1994
|
1.13
|
64
|
The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
|
Proteins
|
1991
|
1.12
|
65
|
Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase.
|
Proc Natl Acad Sci U S A
|
1999
|
1.12
|
66
|
Role of GM1 binding in the mucosal immunogenicity and adjuvant activity of the Escherichia coli heat-labile enterotoxin and its B subunit.
|
Immunology
|
1998
|
1.11
|
67
|
Crystal structure of human branched-chain alpha-ketoacid dehydrogenase and the molecular basis of multienzyme complex deficiency in maple syrup urine disease.
|
Structure
|
2000
|
1.11
|
68
|
Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
|
J Biol Chem
|
1998
|
1.11
|
69
|
Structure of the native cysteine-sulfenic acid redox center of enterococcal NADH peroxidase refined at 2.8 A resolution.
|
Biochemistry
|
1996
|
1.10
|
70
|
Crystal structure of p-hydroxybenzoate hydroxylase complexed with its reaction product 3,4-dihydroxybenzoate.
|
J Mol Biol
|
1988
|
1.10
|
71
|
Selective inhibition of trypanosomal glyceraldehyde-3-phosphate dehydrogenase by protein structure-based design: toward new drugs for the treatment of sleeping sickness.
|
J Med Chem
|
1994
|
1.10
|
72
|
Three-dimensional structure of the human 'protective protein': structure of the precursor form suggests a complex activation mechanism.
|
Structure
|
1995
|
1.09
|
73
|
A mutant cholera toxin B subunit that binds GM1- ganglioside but lacks immunomodulatory or toxic activity.
|
Proc Natl Acad Sci U S A
|
2001
|
1.09
|
74
|
Subtilisin Novo. The three-dimensional structure and its comparison with subtilisin BPN'.
|
Eur J Biochem
|
1972
|
1.08
|
75
|
Structure determination of the glycosomal triosephosphate isomerase from Trypanosoma brucei brucei at 2.4 A resolution.
|
J Mol Biol
|
1987
|
1.08
|
76
|
Crystal structure of recombinant triosephosphate isomerase from Bacillus stearothermophilus. An analysis of potential thermostability factors in six isomerases with known three-dimensional structures points to the importance of hydrophobic interactions.
|
Protein Sci
|
1995
|
1.07
|
77
|
Three-dimensional structure of the quinoprotein methylamine dehydrogenase from Paracoccus denitrificans determined by molecular replacement at 2.8 A resolution.
|
Proteins
|
1992
|
1.07
|
78
|
Crystal structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Leishmania mexicana: implications for structure-based drug design and a new position for the inorganic phosphate binding site.
|
Biochemistry
|
1995
|
1.06
|
79
|
Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin.
|
Infect Immun
|
1996
|
1.06
|
80
|
Crystal structure of fructose-1,6-bisphosphate aldolase from the human malaria parasite Plasmodium falciparum.
|
Biochemistry
|
1998
|
1.05
|
81
|
Structural studies of receptor binding by cholera toxin mutants.
|
Protein Sci
|
1997
|
1.05
|
82
|
Three hTIM mutants that provide new insights on why TIM is a dimer.
|
J Mol Biol
|
1996
|
1.05
|
83
|
Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring.
|
Biochemistry
|
1994
|
1.04
|
84
|
Structure determination of Panulirus interruptus haemocyanin at 3.2 A resolution. Successful phase extension by sixfold density averaging.
|
J Mol Biol
|
1986
|
1.03
|
85
|
Structures of type 2 peroxisomal targeting signals in two trypanosomatid aldolases.
|
J Mol Biol
|
2000
|
1.01
|
86
|
Structure-based exploration of the ganglioside GM1 binding sites of Escherichia coli heat-labile enterotoxin and cholera toxin for the discovery of receptor antagonists.
|
Biochemistry
|
1999
|
1.00
|
87
|
Purification, crystallization and preliminary X-ray investigation of quinoprotein methylamine dehydrogenase from Thiobacillus versutus.
|
Eur J Biochem
|
1986
|
1.00
|
88
|
Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design.
|
J Med Chem
|
2001
|
1.00
|
89
|
Anion-coordinating residues at binding site 1 are essential for the biological activity of the diphtheria toxin repressor.
|
Infect Immun
|
1999
|
0.99
|
90
|
Crystal structure of the reduced form of p-hydroxybenzoate hydroxylase refined at 2.3 A resolution.
|
Proteins
|
1992
|
0.98
|
91
|
Calcium binding to thermitase. Crystallographic studies of thermitase at 0, 5, and 100 mM calcium.
|
J Biol Chem
|
1991
|
0.98
|
92
|
Mutational analysis of the role of ADP-ribosylation activity and GM1-binding activity in the adjuvant properties of the Escherichia coli heat-labile enterotoxin towards intranasally administered keyhole limpet hemocyanin.
|
Eur J Immunol
|
1998
|
0.97
|
93
|
Crystallographic and enzymatic investigations on the role of Ser558, His610, and Asn614 in the catalytic mechanism of Azotobacter vinelandii dihydrolipoamide acetyltransferase (E2p).
|
Biochemistry
|
1995
|
0.97
|
94
|
In search of new lead compounds for trypanosomiasis drug design: a protein structure-based linked-fragment approach.
|
J Comput Aided Mol Des
|
1992
|
0.97
|
95
|
Refined crystal structure of the catalytic domain of dihydrolipoyl transacetylase (E2p) from Azotobacter vinelandii at 2.6 A resolution.
|
J Mol Biol
|
1993
|
0.97
|
96
|
An unexpected extended conformation for the third TPR motif of the peroxin PEX5 from Trypanosoma brucei.
|
J Mol Biol
|
2001
|
0.96
|
97
|
Crystallographic investigations of the tryptophan-derived cofactor in the quinoprotein methylamine dehydrogenase.
|
FEBS Lett
|
1991
|
0.96
|
98
|
Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor.
|
Biochemistry
|
1992
|
0.96
|
99
|
A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana.
|
Structure
|
2000
|
0.96
|
100
|
Intermolecular interactions between the A and B subunits of heat-labile enterotoxin from Escherichia coli promote holotoxin assembly and stability in vivo.
|
Proc Natl Acad Sci U S A
|
1992
|
0.95
|
101
|
Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
|
Biochemistry
|
1993
|
0.95
|
102
|
The Arg7Lys mutant of heat-labile enterotoxin exhibits great flexibility of active site loop 47-56 of the A subunit.
|
Biochemistry
|
1995
|
0.95
|
103
|
Protein crystallography and infectious diseases.
|
Protein Sci
|
1994
|
0.95
|
104
|
Structural foundation for the design of receptor antagonists targeting Escherichia coli heat-labile enterotoxin.
|
Structure
|
1997
|
0.94
|
105
|
Pseudo 2-fold symmetry in the copper-binding domain of arthropodan haemocyanins. Possible implications for the evolution of oxygen transport proteins.
|
J Mol Biol
|
1989
|
0.94
|
106
|
The role of waters in docking strategies with incremental flexibility for carbohydrate derivatives: heat-labile enterotoxin, a multivalent test case.
|
J Med Chem
|
1999
|
0.94
|
107
|
Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants.
|
Structure
|
1995
|
0.93
|
108
|
The high resolution three-dimensional structure of bovine liver rhodanese.
|
Fundam Appl Toxicol
|
1984
|
0.93
|
109
|
Conformational changes in Leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase induced by designed inhibitors.
|
J Mol Biol
|
2001
|
0.93
|
110
|
Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine.
|
J Med Chem
|
2000
|
0.93
|
111
|
Selective tight binding inhibitors of trypanosomal glyceraldehyde-3-phosphate dehydrogenase via structure-based drug design.
|
J Med Chem
|
1998
|
0.92
|
112
|
Comparison of the B-pentamers of heat-labile enterotoxin and verotoxin-1: two structures with remarkable similarity and dissimilarity.
|
Biochemistry
|
1993
|
0.92
|
113
|
Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid and glutarate: insight into the basis of its substrate specificity.
|
Chem Biol
|
2001
|
0.92
|
114
|
Analysis of the active site of the flavoprotein p-hydroxybenzoate hydroxylase and some ideas with respect to its reaction mechanism.
|
Biochemistry
|
1990
|
0.91
|
115
|
Structure of partially-activated E. coli heat-labile enterotoxin (LT) at 2.6 A resolution.
|
FEBS Lett
|
1994
|
0.91
|
116
|
Synthesis and structure-activity relationships of analogs of 2'-deoxy-2'-(3-methoxybenzamido)adenosine, a selective inhibitor of trypanosomal glycosomal glyceraldehyde-3-phosphate dehydrogenase.
|
J Med Chem
|
1995
|
0.91
|
117
|
A bisubstrate analog induces unexpected conformational changes in phosphoglycerate kinase from Trypanosoma brucei.
|
J Mol Biol
|
1998
|
0.90
|
118
|
Preliminary crystallographic studies of triosephosphate isomerase from the blood parasite Trypanosoma brucei brucei.
|
J Mol Biol
|
1984
|
0.89
|
119
|
Heat-labile enterotoxin of Escherichia coli. Characterization of different crystal forms.
|
J Biol Chem
|
1985
|
0.89
|
120
|
On the role of the active site helix in papain, an ab initio molecular orbital study.
|
Biophys Chem
|
1979
|
0.89
|
121
|
Three-dimensional structure of lipoamide dehydrogenase from Pseudomonas fluorescens at 2.8 A resolution. Analysis of redox and thermostability properties.
|
J Mol Biol
|
1993
|
0.89
|
122
|
Comparison of high-resolution structures of the diphtheria toxin repressor in complex with cobalt and zinc at the cation-anion binding site.
|
Protein Sci
|
1997
|
0.89
|
123
|
The catalytic domain of the dihydrolipoyl transacetylase component of the pyruvate dehydrogenase complex from Azotobacter vinelandii and Escherichia coli. Expression, purification, properties and preliminary X-ray analysis.
|
Eur J Biochem
|
1991
|
0.88
|
124
|
Protein engineering studies of A-chain loop 47-56 of Escherichia coli heat-labile enterotoxin point to a prominent role of this loop for cytotoxicity.
|
Mol Microbiol
|
1996
|
0.88
|
125
|
Use of electron microscopy in the examination of lattice defects in crystals of alcohol oxidase.
|
FEBS Lett
|
1989
|
0.87
|
126
|
Crystallographic and molecular modeling studies on trypanosomal triosephosphate isomerase: a critical assessment of the predicted and observed structures of the complex with 2-phosphoglycerate.
|
J Med Chem
|
1991
|
0.87
|
127
|
Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
|
Acta Crystallogr D Biol Crystallogr
|
2001
|
0.87
|
128
|
Structure of the complex between trypanosomal triosephosphate isomerase and N-hydroxy-4-phosphono-butanamide: binding at the active site despite an "open" flexible loop conformation.
|
Protein Sci
|
1992
|
0.86
|
129
|
Anion binding at the active site of trypanosomal triosephosphate isomerase. Monohydrogen phosphate does not mimic sulphate.
|
Eur J Biochem
|
1991
|
0.86
|
130
|
Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant.
|
Protein Sci
|
1997
|
0.85
|
131
|
X-ray structure of lipoamide dehydrogenase from Azotobacter vinelandii determined by a combination of molecular and isomorphous replacement techniques.
|
J Mol Biol
|
1989
|
0.85
|
132
|
Solid-phase synthesis of N-acyl-N'-alkyl/aryl disubstituted guanidines.
|
J Org Chem
|
2001
|
0.85
|
133
|
Improvement of diffraction quality upon rehydration of dehydrated icosahedral Enterococcus faecalis pyruvate dehydrogenase core crystals.
|
Protein Sci
|
1997
|
0.85
|
134
|
The coenzyme analogue adenosine 5-diphosphoribose displaces FAD in the active site of p-hydroxybenzoate hydroxylase. An x-ray crystallographic investigation.
|
Biochemistry
|
1989
|
0.84
|
135
|
The atomic model of the human protective protein/cathepsin A suggests a structural basis for galactosialidosis.
|
Proc Natl Acad Sci U S A
|
1998
|
0.84
|
136
|
Tumor marker disaccharide D-Gal-beta 1, 3-GalNAc complexed to heat-labile enterotoxin from Escherichia coli.
|
Protein Sci
|
1996
|
0.84
|
137
|
Crystal structure of heat-labile enterotoxin from Escherichia coli with increased thermostability introduced by an engineered disulfide bond in the A subunit.
|
Protein Sci
|
1997
|
0.84
|
138
|
Papain in water-rich and in methanol-rich media; crystallization and conformation.
|
J Mol Biol
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