Published in Science on July 01, 1983
Monocyte-conditioned medium, interleukin-1, and tumor necrosis factor stimulate the acute phase response in human hepatoma cells in vitro. J Cell Biol (1986) 3.20
Isolation and sequence of a human apolipoprotein CII cDNA clone and its use to isolate and map to human chromosome 19 the gene for apolipoprotein CII. Proc Natl Acad Sci U S A (1984) 1.91
Inducible and tissue-specific expression of human C-reactive protein in transgenic mice. EMBO J (1987) 1.51
Identification of sequences responsible for acute-phase induction of human C-reactive protein. Nucleic Acids Res (1988) 1.44
Linking C-reactive protein to late-life disability in the National Health and Nutrition Examination Survey (NHANES) 1999-2002. J Gerontol A Biol Sci Med Sci (2006) 1.40
Expression of murine 21-hydroxylase in mouse adrenal glands and in transfected Y1 adrenocortical tumor cells. Proc Natl Acad Sci U S A (1985) 1.20
Acute phase reactants as novel predictors of cardiovascular disease. ISRN Inflamm (2012) 0.87
A new surgical technique versus an old marker: can expansion sphincter pharyngoplasty reduce C-reactive protein levels in patients with obstructive sleep apnea? Eur Arch Otorhinolaryngol (2016) 0.75
Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS). Nucleic Acids Res (1989) 15.35
Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature (1984) 10.52
A novel, rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones. Nucleic Acids Res (1990) 8.52
Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. Science (1987) 8.29
Rapid synthesis of oligodeoxyribonucleotides. IV. Improved solid phase synthesis of oligodeoxyribonucleotides through phosphotriester intermediates. Nucleic Acids Res (1980) 7.01
Role of pili in adherence of Pseudomonas aeruginosa to mammalian buccal epithelial cells. Infect Immun (1980) 6.19
Burkholderia thailandensis sp. nov., a Burkholderia pseudomallei-like species. Int J Syst Bacteriol (1998) 5.34
Human von Willebrand factor (vWF): isolation of complementary DNA (cDNA) clones and chromosomal localization. Science (1985) 5.23
Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping. Nature (1990) 5.13
Serum amyloid A, the major vertebrate acute-phase reactant. Eur J Biochem (1999) 4.94
Efflux-mediated aminoglycoside and macrolide resistance in Burkholderia pseudomallei. Antimicrob Agents Chemother (1999) 4.29
A rat model of chronic respiratory infection with Pseudomonas aeruginosa. Am Rev Respir Dis (1979) 4.27
Vertebrate pseudogenes. FEBS Lett (2000) 3.93
Isolation of cDNA clones for the human complement protein factor B, a class III major histocompatibility complex gene product. Proc Natl Acad Sci U S A (1982) 3.89
Characterization and use of a DNA probe as an epidemiological marker for Pseudomonas aeruginosa. J Infect Dis (1987) 3.79
Synthesis of the second component of complement by long-term primary cultures of human monocytes. J Exp Med (1976) 3.64
Mutagenesis of Burkholderia pseudomallei with Tn5-OT182: isolation of motility mutants and molecular characterization of the flagellin structural gene. J Bacteriol (1997) 3.60
Intracellular survival of Burkholderia pseudomallei. Infect Immun (1996) 3.56
Role of fibronectin in the prevention of adherence of Pseudomonas aeruginosa to buccal cells. J Infect Dis (1981) 3.51
Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain. Nature (1986) 3.50
Isolation of cDNA clones encoding the 20K T3 glycoprotein of human T-cell receptor complex. Nature (1985) 3.34
The T cell receptor beta chain genes are located on chromosome 6 in mice and chromosome 7 in humans. Cell (1984) 3.34
Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase. Proc Natl Acad Sci U S A (1983) 3.33
Brief report: deficiency of pulmonary surfactant protein B in congenital alveolar proteinosis. N Engl J Med (1993) 3.33
Alternate-day prednisone reduces morbidity and improves pulmonary function in cystic fibrosis. Lancet (1985) 3.32
The common 'thermolabile' variant of methylene tetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia. QJM (1996) 3.31
Role of adherence in the pathogenesis of Pseudomonas aeruginosa lung infection in cystic fibrosis patients. Infect Immun (1980) 3.23
Inhibition of phagocytosis of complement C3- or immunoglobulin G-coated particles and of C3bi binding by monoclonal antibodies to a monocyte-granulocyte membrane glycoprotein (Mol). J Clin Invest (1983) 3.23
Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease. Nat Genet (2001) 3.15
The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein. Immunol Today (1994) 3.13
Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression. J Clin Invest (1986) 3.05
Homozygous deficiency of C3 in a patient with repeated infections. Lancet (1972) 3.04
Epidemiology of sporadic diarrhea due to verocytotoxin-producing Escherichia coli: a two-year prospective study. J Infect Dis (1988) 3.01
Diagnosis of alpha 1-antitrypsin deficiency by enzymatic amplification of human genomic DNA and direct sequencing of polymerase chain reaction products. Nucleic Acids Res (1988) 3.00
A mutation in the surfactant protein B gene responsible for fatal neonatal respiratory disease in multiple kindreds. J Clin Invest (1994) 2.98
Solid phase phosphotriester synthesis of large oligodeoxyribonucleotides on a polyamide support. Nucleic Acids Res (1980) 2.96
The gene encoding the epsilon subunit of the T3/T-cell receptor complex maps to chromosome 11 in humans and to chromosome 9 in mice. Proc Natl Acad Sci U S A (1987) 2.91
Pretranslational modulation of acute phase hepatic protein synthesis by murine recombinant interleukin 1 (IL-1) and purified human IL-1. J Exp Med (1985) 2.84
Detection of bacterial virulence genes by subtractive hybridization: identification of capsular polysaccharide of Burkholderia pseudomallei as a major virulence determinant. Infect Immun (2001) 2.76
Total synthesis of a human leukocyte interferon gene. Nature (1981) 2.76
Contribution of toxin A and elastase to virulence of Pseudomonas aeruginosa in chronic lung infections of rats. Infect Immun (1982) 2.76
mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification. Nature (1983) 2.72
Effect of rpoS mutation on the stress response and expression of virulence factors in Pseudomonas aeruginosa. J Bacteriol (1999) 2.72
Association of respiratory tract colonization with adherence of gram-negative bacilli to epithelial cells. J Infect Dis (1979) 2.70
Sequence of cDNA encoding human insulin-like growth factor I precursor. Nature (1984) 2.69
Characterization of Burkholderia pseudomallei and Burkholderia pseudomallei-like strains. Epidemiol Infect (1997) 2.69
The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome. Proc Natl Acad Sci U S A (1990) 2.68
EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle. Oncogene (1998) 2.65
Localization of gelsolin proximal to ABL on chromosome 9. Am J Hum Genet (1988) 2.64
Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal carcinoma. Gut (2000) 2.56
Identification of a Burkholderia mallei polysaccharide gene cluster by subtractive hybridization and demonstration that the encoded capsule is an essential virulence determinant. Microb Pathog (2001) 2.52
A 3.5 genome equivalent multi access YAC library: construction, characterisation, screening and storage. Nucleic Acids Res (1990) 2.51
Homozygosity of chromosome 13 in retinoblastoma. N Engl J Med (1984) 2.49
Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13). Hum Mol Genet (2001) 2.48
Deficiency of a granulocyte-membrane glycoprotein (gp150) in a boy with recurrent bacterial infections. N Engl J Med (1982) 2.47
The type II O-antigenic polysaccharide moiety of Burkholderia pseudomallei lipopolysaccharide is required for serum resistance and virulence. Mol Microbiol (1998) 2.46
Abrogation of the alternative complement pathway by targeted deletion of murine factor B. Proc Natl Acad Sci U S A (1997) 2.44
Biosynthesis of complement. Adv Immunol (1976) 2.36
Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells. J Biol Chem (1992) 2.35
Human adenosine deaminase. cDNA and complete primary amino acid sequence. J Biol Chem (1984) 2.33
The second locus for autosomal recessive primary microcephaly (MCPH2) maps to chromosome 19q13.1-13.2. Eur J Hum Genet (2000) 2.31
Molecular map of the murine S region. Proc Natl Acad Sci U S A (1983) 2.24
Characterization of Pseudomonas cepacia isolates from patients with cystic fibrosis. J Clin Microbiol (1984) 2.23
Report of the committee on the genetic constitution of chromosome 1. Cytogenet Cell Genet (1989) 2.18
Quantification of the close association between DNA haplotypes and specific beta-thalassaemia mutations in Mediterraneans. Nature (1984) 2.18
Thermolabile variant of 5,10-methylenetetrahydrofolate reductase associated with low red-cell folates: implications for folate intake recommendations. Lancet (1997) 2.10
Warfarin response and vitamin K epoxide reductase complex 1 in African Americans and Caucasians. Clin Pharmacol Ther (2007) 2.01
Polymorphism of the human complement C4 and steroid 21-hydroxylase genes. Restriction fragment length polymorphisms revealing structural deletions, homoduplications, and size variants. J Clin Invest (1986) 2.00
Primary autosomal recessive microcephaly (MCPH1) maps to chromosome 8p22-pter. Am J Hum Genet (1998) 2.00
Assignment of the structural gene for the third component of human complement to chromosome 19. Proc Natl Acad Sci U S A (1982) 2.00
Hyperkalemic periodic paralysis and the adult muscle sodium channel alpha-subunit gene. Science (1990) 1.99
Human profilin. Molecular cloning, sequence comparison, and chromosomal analysis. J Biol Chem (1988) 1.97
Screening for cystic fibrosis; public policy and personal choices. N Engl J Med (1990) 1.97
Direct detection of the common Mediterranean beta-thalassemia gene with synthetic DNA probes. An alternative approach for prenatal diagnosis. J Clin Invest (1983) 1.95
The "thermolabile" variant of methylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother. Am J Hum Genet (1999) 1.94
A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32. J Immunol (1987) 1.94
Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA. Immunopharmacology (1999) 1.94
beta-Thalassemia in Chinese: use of in vivo RNA analysis and oligonucleotide hybridization in systematic characterization of molecular defects. Proc Natl Acad Sci U S A (1984) 1.92
Cloning and characterization of two human skeletal muscle alpha-actinin genes located on chromosomes 1 and 11. J Biol Chem (1992) 1.91
Isolation and sequence of a human apolipoprotein CII cDNA clone and its use to isolate and map to human chromosome 19 the gene for apolipoprotein CII. Proc Natl Acad Sci U S A (1984) 1.91
Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease. J Clin Invest (1990) 1.91
Dosing algorithms to predict warfarin maintenance dose in Caucasians and African Americans. Clin Pharmacol Ther (2008) 1.90
Rheumatoid arthritis. Biosynthesis of complement proteins by synovial tissues. N Engl J Med (1974) 1.88
Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages. Proc Natl Acad Sci U S A (1985) 1.85
The beta-subunit of follicle-stimulating hormone is deleted in patients with aniridia and Wilms' tumour, allowing a further definition of the WAGR locus. Nature (1986) 1.84
Regulation of serum amyloid A protein expression during the acute-phase response. Biochem J (1998) 1.83
Use of a cDNA clone for the fourth component of human complement (C4) for analysis of a genetic deficiency of C4 in guinea pig. Proc Natl Acad Sci U S A (1983) 1.82
Demonstration of an iron-siderophore-binding protein in the outer membrane of Pseudomonas aeruginosa. Infect Immun (1983) 1.82
Alu sequences. FEBS Lett (1997) 1.81
Cell-free synthesis of the fourth component of guinea pig complement (C4): identification of a precursor of serum C4 (pro-C4). Proc Natl Acad Sci U S A (1977) 1.79
Characterization of genomic and complementary DNA sequence of human C-reactive protein, and comparison with the complementary DNA sequence of serum amyloid P component. J Biol Chem (1985) 1.79