Published in J Exp Med on August 01, 1977
Inhibition of dual Ir gene-controlled T-lymphocyte proliferative response to poly (Glu56Lys35Phe9)n with anti-Ia antisera directed against products of either I-A or I-C subregion. Proc Natl Acad Sci U S A (1978) 1.55
Monoclonal antibodies to guinea pig Ia antigens. II. Effect on alloantigen-, antigen-, and mitogen-induced T lymphocyte proliferation in vitro. J Exp Med (1980) 1.17
The role of rabbit Ia molecules in immune functions as determined with the use of an anti-Ia monoclonal antibody. Immunology (1984) 0.97
Genetic control of allogeneic interactions in the guinea-pig. V. Evidence for a dissociation between genes coding for A GPLA-B region-controlled determinant and genes coding for MLC suppressor cells. Immunology (1983) 0.75
Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes. J Exp Med (1973) 11.59
The H-2 major histocompatibility complex and the I immune response region: genetic variation, function, and organization. Adv Immunol (1975) 9.19
Cell interactions between histoincompatible T and B lymphocytes. VII. Cooperative responses between lymphocytes are controlled by genes in the I region of the H-2 complex. J Exp Med (1975) 7.64
Histocompatibility-linked immune response gene function in guinea pigs. Specific inhibition of antigen-induced lymphocyte proliferation by alloantisera. J Exp Med (1972) 3.81
The peritoneal exudate lymphocyte. I. Differences in antigen responsiveness between peritoneal exudate and lymph node lymphocytes from immunized guinea pigs. J Exp Med (1971) 3.81
Role of major histocompatibility complex gene products in delayed-type hypersensitivity. Proc Natl Acad Sci U S A (1976) 3.69
Specific immune response genes of the guinea pig. I. Dominant genetic control of immune responsiveness to copolymers of L-glutamic acid and L-alanine and L-glutamic acid and L-tyrosine. J Exp Med (1971) 1.64
The function of macrophages in antigen recognition by guinea pig T lymphocytes. III. Genetic analysis of the antigens mediating macrophage-T lymphocyte interaction. J Immunol (1976) 1.54
Hapten-specific augmentation of the anti-idiotype antibody response to hapten-myeloma protein conjugates in mice. Eur J Immunol (1973) 1.37
A simple and versatile harvesting device for processing radioactive label incorporated into and-or released from cells in microculture. J Immunol Methods (1974) 1.32
Inclusion group systems and cis-trans effects in responses controlled by the two complementing Ir-GLphi genes. J Exp Med (1976) 1.29
Structural control of immunogenicity. II. Antibody synthesis and cellular immunity in response to immunization with mono-epsilon-oligo-L-lysines. Immunology (1971) 1.19
Private specificities of H-2K and H-2D loci as possible selective targets for effector lymphocytes in cell-mediated immunity. J Exp Med (1975) 1.04
The guinea pig I region. I. A structural and genetic analysis. J Exp Med (1977) 0.86
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med (1998) 19.03
Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes. J Exp Med (1973) 11.59
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol (2000) 9.15
CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J Immunol (1998) 7.31
Function of macrophages in antigen recognition by guinea pig T lymphocytes. II. Role of the macrophage in the regulation of genetic control of the immune response. J Exp Med (1973) 7.14
Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2. J Immunol (1984) 5.51
Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex. Proc Natl Acad Sci U S A (1983) 4.83
IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression. J Immunol (1993) 4.65
An improved method for isolation of H-2 and Ia alloantigens with immunoprecipitation induced by protein A-bearing staphylococci. J Immunol (1976) 4.55
Immunologic functions of Ia-bearing epidermal Langerhans cells. J Immunol (1978) 4.55
Macrophage Ia antigens. I. macrophage populations differ in their expression of Ia antigens. J Immunol (1978) 4.04
Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells. J Immunol (2001) 3.99
The effects of cyclosporin A on the immune system. Annu Rev Immunol (1985) 3.86
Histocompatibility-linked immune response gene function in guinea pigs. Specific inhibition of antigen-induced lymphocyte proliferation by alloantisera. J Exp Med (1972) 3.81
Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box. Proc Natl Acad Sci U S A (1988) 3.64
Receptors for complement and immunoglobulin on human leukemic cells and human lymphoblastoid cell lines. J Clin Invest (1972) 3.64
Immunoglobulin and theta-bearing murine leukemias and lymphomas. J Immunol (1972) 3.41
Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort. N Engl J Med (1999) 3.30
T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4. J Exp Med (1984) 3.26
IL-10 inhibits mitogen-induced T cell proliferation by selectively inhibiting macrophage costimulatory function. J Immunol (1992) 2.89
Evidence for a specific B27-associated cell surface marker on lymphocytes of patients with ankylosing spondylitis. Nature (1979) 2.79
Characterization of bullous pemphigoid antigen: a unique basement membrane protein of stratified squamous epithelia. Cell (1981) 2.72
Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. J Exp Med (1994) 2.70
IL-12 unmasks latent autoimmune disease in resistant mice. J Exp Med (1996) 2.69
The murine IL 2 receptor. I. Monoclonal antibodies that define distinct functional epitopes on activated T cells and react with activated B cells. J Immunol (1984) 2.60
A factor(s) in Klebsiella culture filtrates specifically modifies an HLA-B27 associated cell-surface component. Nature (1980) 2.49
Dendritic cells with antigen-presenting capability reside in airway epithelium, lung parenchyma, and visceral pleura. J Exp Med (1986) 2.45
Receptors for complement and immunoglobulin on human and animal lymphoid cells. Transplant Rev (1973) 2.43
Nodular lymphoma--evidence for origin from follicular B lymphocytes. N Engl J Med (1974) 2.26
An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease. J Exp Med (1998) 2.26
Isolation of H-2 alloantigens solubilized by the detergent NP-40. J Immunol (1971) 2.26
Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. J Immunol (1988) 2.17
Identification of a T3-associated gamma delta T cell receptor on Thy-1+ dendritic epidermal Cell lines. Science (1987) 2.12
The distribution of histocompatibility antigens on T and B cells in the guinea pig. Transplantation (1973) 2.12
Nature of the antigenic complex recognized by T lymphocytes: specific sensitization by antigens associated with allogeneic macrophages. Proc Natl Acad Sci U S A (1977) 2.10
B cell stimulatory factor 1 (interleukin 4) is a potent costimulant for normal resting T lymphocytes. J Exp Med (1987) 2.09
Nucleotide sequence and expression of a mouse interleukin 2 receptor cDNA. J Immunol (1985) 2.00
HLA-B27, Klebsiella and ankylosing spondylitis: biological and chemical studies. Immunol Rev (1983) 1.99
The expression of Ia antigens on immunocompetent cells in the guinea pig. II. Ia antigens on macrophages. J Immunol (1977) 1.96
The Thy-1-bearing cell of murine epidermis. A distinctive leukocyte perhaps related to natural killer cells. J Exp Med (1985) 1.93
Detection of Ia antigens on Langerhans cells in guinea pig skin. J Immunol (1978) 1.90
Independent populations of primed F1 guinea pig T lymphocytes respond to antigen-pulsed parental peritoneal exudate cells. J Exp Med (1977) 1.88
Preferential cutaneous infiltration by neoplastic thymus-derived lymphocytes. Morphologic and functional studies. Ann Intern Med (1974) 1.87
Transplantation and preliminary characterisation of lymphocyte surface markers of Abelson virus-induced lymphomas. Nature (1975) 1.87
Role of Ly-6 in lymphocyte activation. II. Induction of T cell activation by monoclonal anti-Ly-6 antibodies. J Exp Med (1986) 1.87
Adhesion molecules: a rheumatologic perspective. Arthritis Rheum (1997) 1.80
Interleukin 7 is a T-cell growth factor. Proc Natl Acad Sci U S A (1989) 1.79
Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects. Arthritis Rheum (1998) 1.79
Safety of tacrolimus in patients with rheumatoid arthritis: long-term experience. Rheumatology (Oxford) (2004) 1.76
Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes. Nature (1986) 1.76
Chromosomal location of the Ly-49 (A1, YE1/48) multigene family. Genetic association with the NK 1.1 antigen. J Immunol (1990) 1.74
Analogous functions of macrophages and Langerhans cells in the initiation in the immune response. J Invest Dermatol (1978) 1.71
Production of autoreactive I region-restricted T cell hybridomas. J Exp Med (1982) 1.70
Genetic restriction in T-lymphocyte activation by antigen-pulse peritoneal exudate cells. Cold Spring Harb Symp Quant Biol (1977) 1.70
The distribution of alloantigenic specificities of native H-2 products. J Immunol (1972) 1.69
A murine T lymphocyte antigen belongs to a supergene family of type II integral membrane proteins. J Immunol (1989) 1.69
H-2 histocompatibility alloantigens. Some biochemical properties of the molecules solubilized by NP-40 detergent. Biochemistry (1973) 1.68
Nature of the antigenic complex recognized by T lymphocytes. I. Analysis with an in vitro primary response to soluble protein antigens. J Exp Med (1976) 1.68
Studies of Ia antigens on murine peritoneal macrophages. Scand J Immunol (1976) 1.66
Strong human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte activity in Sydney Blood Bank Cohort patients infected with nef-defective HIV type 1. J Virol (1999) 1.63
Pathogenesis of post-thymectomy autoimmune gastritis. Identification of anti-H/K adenosine triphosphatase-reactive T cells. J Immunol (1996) 1.60
Role of the L3T4-antigen in T cell activation. II. Inhibition of T cell activation by monoclonal anti-L3T4 antibodies in the absence of accessory cells. J Immunol (1985) 1.57
Regeneration of transplantation antigens on mouse cells. Transplant Proc (1971) 1.56
CD59 functions as a signal-transducing molecule for human T cell activation. J Immunol (1991) 1.56
Pathogenesis of post-thymectomy autoimmunity. Role of syngeneic MLR-reactive T cells. J Immunol (1995) 1.55
Lymphocyte transformation in contact sensitivity. Immunology (1970) 1.54
The function of macrophages in antigen recognition by guinea pig T lymphocytes. III. Genetic analysis of the antigens mediating macrophage-T lymphocyte interaction. J Immunol (1976) 1.54
L2C Guinea pig lymphatic leukemia: a "B" cell leukemia. Blood (1972) 1.52
IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease. Immunol Today (1996) 1.52
Both interleukin 2 and a second T cell-derived factor in EL-4 supernatant have activity as differentiation factors in IgM synthesis. J Exp Med (1984) 1.51
Thy-1+ dendritic epidermal cells belong to the T-cell lineage. Proc Natl Acad Sci U S A (1987) 1.46
Alloantiserum-induced inhibition of immune response gene product function. II. Genetic analysis of target antigens. J Exp Med (1974) 1.45
Guinea-pig Ia antigens: functional significance and chemical characterization. Transplant Rev (1976) 1.44
Macrophage-lymphocyte interaction and antigen recognition. Fed Proc (1975) 1.44
Association of HLA-DRw4 with rheumatoid arthritis in black and white patients. Arthritis Rheum (1980) 1.42
A T cell receptor transgenic model of severe, spontaneous organ-specific autoimmunity. Eur J Immunol (2001) 1.41
Thy-1-mediated T-cell activation requires co-expression of CD3/Ti complex. Nature (1987) 1.41
Infection breaks T-cell tolerance. Nature (1992) 1.41
The murine IL 2 receptor. III. Cellular requirements for the induction of IL 2 receptor expression on T cell subpopulations. J Immunol (1985) 1.40
The syngeneic mixed leukocyte reaction: the genetic requirements for the recognition of self resemble the requirements for the recognition of antigen in association with self. J Immunol (1980) 1.40
Regulation of interleukin (IL)-12 receptor beta2 subunit expression by endogenous IL-12: a critical step in the differentiation of pathogenic autoreactive T cells. J Exp Med (1999) 1.40
Leukemic reticuloendotheliosis: presence of a receptor for cytophilic antibody. Am J Med (1974) 1.37
Ly-6: a multigene family in search of a function. Immunol Today (1989) 1.34
The murine IL 2 receptor. II. Monoclonal anti-IL 2 receptor antibodies as specific inhibitors of T cell function in vitro. J Immunol (1984) 1.34
Molecular characterization of the early activation antigen CD69: a type II membrane glycoprotein related to a family of natural killer cell activation antigens. Eur J Immunol (1993) 1.34
Molecular relationships of the human B cell alloantigens, MT2, MB3, MT4, and DR5. J Immunol (1982) 1.34
Fine specificity of cloned insulin-specific T cell hybridomas: evidence supporting a role for tertiary conformation. J Immunol (1983) 1.33
The histocompatibility restrictions on macrophage T-helper cell interaction determine the histocompatibility restrictions on T-helper cell B-cell interaction. J Exp Med (1978) 1.32
Thy-1- and Ly-6-mediated lymphokine production and growth inhibition of a T cell hybridoma require co-expression of the T cell antigen receptor complex. J Immunol (1988) 1.31
Insertion of Ia and H-2 alloantigens into model membranes. Proc Natl Acad Sci U S A (1979) 1.31
CpG oligonucleotides are potent adjuvants for the activation of autoreactive encephalitogenic T cells in vivo. J Immunol (2000) 1.30
Induction of T cell activation by monoclonal anti-Thy-1 antibodies. J Immunol (1986) 1.30
The role of the macrophage as the stimulator cell in contact sensitivity. J Immunol (1977) 1.28
Pocket 4 of the HLA-DR(alpha,beta 1*0401) molecule is a major determinant of T cells recognition of peptide. J Exp Med (1995) 1.28
Collagen-induced arthritis in the BB rat. Prevention of disease by treatment with CTLA-4-Ig. J Clin Invest (1995) 1.27
HLA-B27, Klebsiella, and ankylosing spondylitis. Lancet (1979) 1.26
Immunochemical characterization of Klebsiella antigens which specifically modify an HLA-B27-associated cell-surface component. Hum Immunol (1982) 1.25
HLA-DR associates with specific stress proteins and is retained in the endoplasmic reticulum in invariant chain negative cells. J Exp Med (1992) 1.25
Post-thymectomy autoimmunity: abnormal T-cell homeostasis. Immunol Today (1995) 1.25