Published in Proc Natl Acad Sci U S A on September 01, 1980
Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cell growth in vitro. Proc Natl Acad Sci U S A (1982) 2.42
Delivery of macromolecules into living cells: a method that exploits folate receptor endocytosis. Proc Natl Acad Sci U S A (1991) 2.16
Immunotoxins for targeted cancer therapy. AAPS J (2006) 1.86
Human trophoblast cell-surface antigens defined by monoclonal antibodies. Proc Natl Acad Sci U S A (1981) 1.59
Antibodies to RNA from autoimmune NZB/NZW mice recognize a similar antigenic determinant and show a large idiotypic diversity. Proc Natl Acad Sci U S A (1982) 1.58
T cell-derived B cell growth and differentiation factors. Dichotomy between the responsiveness of B cells from adult and neonatal mice. J Exp Med (1983) 1.54
Induction of proliferation and differentiation of neoplastic B cells by anti-immunoglobulin and T-cell factors. Proc Natl Acad Sci U S A (1981) 1.12
Monoclonal antibody and an antibody-toxin conjugate to a cell surface proteoglycan of melanoma cells suppress in vivo tumor growth. Proc Natl Acad Sci U S A (1983) 1.12
Recombinant immunotoxins containing truncated bacterial toxins for the treatment of hematologic malignancies. BioDrugs (2009) 1.05
Mutant monoclonal antibodies with alterations in biological functions. J Exp Med (1982) 1.05
Selective cytotoxicity against human tumour cells by a vindesine-monoclonal antibody conjugate. Br J Cancer (1983) 1.02
Tumor dormancy and cell signaling. II. Antibody as an agonist in inducing dormancy of a B cell lymphoma in SCID mice. J Exp Med (1995) 1.02
Therapy of murine leukemia with monoclonal antibody against a normal differentiation antigen. J Exp Med (1983) 1.01
In vivo therapy of a murine B cell tumor (BCL1) using antibody-ricin A chain immunotoxins. J Exp Med (1982) 0.96
Induction of immune cytolysis: tumor-cell killing by complement is initiated by covalent complex of monoclonal antibody and stable C3/C5 convertase. Proc Natl Acad Sci U S A (1981) 0.87
Selective abrogation of antigen-specific human B cell responses by antigen-ricin conjugates. J Exp Med (1982) 0.84
Differential agglutination by soybean agglutinin of human leukemia and neuroblastoma cell lines: potential application to autologous bone marrow transplantation. Proc Natl Acad Sci U S A (1983) 0.83
H-40, an antigen controlled by an Igh linked gene and recognized by cytotoxic T lymphocytes. I. Genetic analysis of H-40 and distribution of its product on B cell tumors. J Exp Med (1984) 0.81
Immunotoxins: a review of their use in cancer treatment. J Stem Cells Regen Med (2006) 0.77
Selective cytotoxicity of ricin A chain immunotoxins towards murine cytomegalovirus-infected cells. Antimicrob Agents Chemother (1996) 0.77
BCL1, a murine model of prolymphocytic leukemia. I. Effect of splenectomy on growth kinetics and organ distribution. Am J Pathol (1981) 0.77
Immunotherapeutic strategies to target prognostic and predictive markers of cancer. Biomark Med (2013) 0.76
Cytotoxic effect of anti-idiotype antibody-chlorambucil conjugates against human lymphoblastoid cells. Immunology (1983) 0.75
BCL1, a murine model of prolymphocytic leukemia. II. Morphology and ultrastructure. Am J Pathol (1981) 0.75
Selective growth-inhibition of multidrug-resistant CHO-cells by the monoclonal antibody 265/F4. Br J Cancer (1991) 0.75
Clinical targeting recombinant immunotoxins for cancer therapy. Onco Targets Ther (2017) 0.75
Addressing the Immunogenicity of the Cargo and of the Targeting Antibodies with a Focus on Demmunized Bacterial Toxins and on Antibody-Targeted Human Effector Proteins. Biomedicines (2017) 0.75
Continuous cultures of fused cells secreting antibody of predefined specificity. Nature (1975) 83.56
Properties of monoclonal antibodies to mouse Ig allotypes, H-2, and Ia antigens. Curr Top Microbiol Immunol (1978) 13.40
Protein thiolation and reversible protein-protein conjugation. N-Succinimidyl 3-(2-pyridyldithio)propionate, a new heterobifunctional reagent. Biochem J (1978) 5.40
Affinity chromatography. Annu Rev Biochem (1971) 3.95
Cell fusion. Methods Enzymol (1979) 2.89
Diphtheria. Science (1973) 2.83
Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis. Biochemistry (1973) 2.30
Similar idiotypic specificity for the membrane IgD and IgM of human B lymphocytes. J Immunol (1975) 2.28
Antibody-linked cytotoxic agents in the treatment of cancer: current status and future prospects. J Natl Cancer Inst (1978) 1.29
Murine B cell leukemia (BCL1): organ distribution and kinetics of growth as determined by fluorescence analysis with an anti-idiotypic antibody. J Immunol (1979) 1.27
The effect of anti-immunoglobulin antibodies on the in vitro proliferation and differentiation of normal and neoplastic murineB cells. J Immunol (1980) 1.26
Characterization of the spontaneous murine B cell leukemia (BCL1). III. Evidence for monoclonality by using an anti-idiotype antibody. J Immunol (1979) 1.18
Chimeric toxins: toxic, disulfide-linked conjugate of concanavalin A with fragment A from diphtheria toxin. Proc Natl Acad Sci U S A (1978) 1.13
Antigen-induced murine B cell lymphomas. I. Induction and characterization of CH1 and CH2. J Immunol (1978) 1.11
A hybrid protein containing the toxic subunit of ricin and the cell-specific subunit of human chorionic gonadotropin. II. Biologic properties. J Biol Chem (1979) 1.05
Antitumor effects of antibody-diphtheria toxin conjugates. II. Immunotherapy with conjugates directed against tumor antigens induced by simian virus 40. J Natl Cancer Inst (1975) 0.99
Reconstitution of hybrid toxin from Fragment A of diphtheria toxin and a subunit of Wistaria floribunda lectin. J Biol Chem (1978) 0.97
Preparation of a hybrid of fragment Fab' of antibody and fragment A of diphtheria toxin and its cytotoxicity. Biochem Biophys Res Commun (1979) 0.94
Increased toxicity of diphtheria toxin for human lymphoblastoid cells following covalent linkage to anti-(human lymphocyte) globulin or its F(ab')2 fragment. Eur J Biochem (1980) 0.91
Allelic exclusion of IgD allotypes on murine B cells. J Immunol (1980) 0.91
Regulatory effect of antibody on the immune response. Adv Immunol (1968) 6.03
Cell surface immunoglobulin. II. Isolation and characterization of immunoglobulin from mouse splenic lymphocytes. J Exp Med (1971) 5.80
Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature (1988) 5.56
Detection and characterization of carcinoma cells in the blood. Proc Natl Acad Sci U S A (1998) 4.76
The carriage of immunological memory by small lymphocytes in the rat. J Exp Med (1966) 4.73
Increased expression of Ia antigens on resting B cells: an additional role for B-cell growth factor. Proc Natl Acad Sci U S A (1984) 4.62
T cell-derived B cell differentiation factor(s). Effect on the isotype switch of murine B cells. J Exp Med (1982) 4.51
Serological, biochemical, and functional identity of B cell-stimulatory factor 1 and B cell differentiation factor for IgG1. J Exp Med (1985) 4.47
Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc Natl Acad Sci U S A (1994) 4.21
Passive sensitization of lymphocytes and macrophages by antigen-antibody complexes. Proc Natl Acad Sci U S A (1965) 3.83
Polyribosomal synthesis and assembly of the H and L chains of gamma globulin. Proc Natl Acad Sci U S A (1966) 3.53
Immunoglobulin-receptors revisited. Science (1975) 3.38
Biochemical evidence linking the GIX thymocyte surface antigen to the gp69/71 envelope glycoprotein of murine leukemia virus. J Exp Med (1975) 3.31
Cell surface immunoglobulin. XI. The appearance of an IgD-like molecule on murine lymphoid cells during ontogeny. J Exp Med (1975) 3.26
Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells. J Exp Med (1988) 3.16
Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. J Clin Invest (1997) 2.99
Primary-type antibody response in vitro. Science (1966) 2.82
Delayed hypersensitivity. Physiol Rev (1966) 2.64
Cell surface immunoglobulin. IV. Distribution among thymocytes, bone mrrow cells, and their derived populations. J Exp Med (1972) 2.50
B-cell growth factor (B-cell growth factor I or B-cell-stimulating factor, provisional 1) is a differentiation factor for resting B cells and may not induce cell growth. Proc Natl Acad Sci U S A (1985) 2.41
Functional and ontogenetic analysis of murine CD45Rhi and CD45Rlo CD4+ T cells. J Immunol (1990) 2.41
Isolation of heavy and light chains of immunoglobulin from the surfaces of lymphoid cells. J Immunol (1971) 2.35
COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex. Proc Natl Acad Sci U S A (1996) 2.28
Organization of the immune response genes. Science (1979) 2.18
Vascular leak syndrome: a side effect of immunotherapy. Immunopharmacology (1997) 2.07
Mechanisms underlying binding of immune complexes to macrophages. J Exp Med (1971) 2.00
The kinetics of antibody formation. Prog Allergy (1967) 1.92
The differential expression of homing and adhesion molecules on virgin and memory T cells in the mouse. Cell Immunol (1991) 1.88
B cell-stimulatory factor 1 (BSF-1) promotes growth of helper T cell lines. J Exp Med (1986) 1.82
Monitoring expression of HER-2 on circulating epithelial cells in patients with advanced breast cancer. Int J Oncol (2002) 1.81
Redesigning nature's poisons to create anti-tumor reagents. Science (1987) 1.81
Association of a beta2-microglobulin-like subunit with H-2 and TL alloantigens on murine thymocytes. J Immunol (1975) 1.79
The response of lymphocytes from non-immunized humans to antigen-antibody complexes. Clin Exp Immunol (1968) 1.79
Synthesis of germ-line gamma 1 immunoglobulin heavy-chain transcripts in resting B cells: induction by interleukin 4 and inhibition by interferon gamma. Proc Natl Acad Sci U S A (1989) 1.78
Immunoglobulin synthesis and secretion. II. Radioautographic studies of sites of addition of carbohydrate moieties and intracellular transport. J Cell Biol (1970) 1.78
Regulation of antibody formation by serum antibody. I. Removal of specific antibody by means of immunoadsorption. J Exp Med (1969) 1.76
Structural similarities between a product of the T/t-locus isolated from sperm and teratoma cells, and H-2 antigens isolated from splenocytes. Proc Natl Acad Sci U S A (1975) 1.76
The protein products of the murine 17th chromosome: genetics and structure. Adv Immunol (1978) 1.76
Induction of B cell differentiation by T cell factors. I. Stimulation of IgM secretion by products of a T cell hybridoma and a T cell line. J Immunol (1981) 1.73
Activation of antigen-specific B cells: role of T cells, cytokines, and antigen in induction of growth and differentiation. Proc Natl Acad Sci U S A (1983) 1.73
The relationship between surface immunoglobulin isotype and immune function of murine B lymphocytes. I. Surface immunoglobulin isotypes on primed B cells in the spleen. J Exp Med (1977) 1.71
Regulation of antibody formation by serum antibody. II. Removal of specific antibody by means of exchange transfusion. J Exp Med (1970) 1.70
Cell surface immunoglobulin. X. Identification of an IgD-like molecule on the surface of murine splenocytes. J Exp Med (1974) 1.70
Synthesis of excess light chains of gamma globulin by rabbit lymph node cells. Nature (1966) 1.66
Immunotoxins: a new approach to cancer therapy. Science (1983) 1.65
T-cell-derived lymphokines that induce IgM and IgG secretion in activated murine B cells. Immunol Rev (1984) 1.65
Highly purified CD25- resting T cells cannot be infected de novo with HIV-1. Proc Natl Acad Sci U S A (1997) 1.62
Up-regulation of endoglin on vascular endothelial cells in human solid tumors: implications for diagnosis and therapy. Clin Cancer Res (1995) 1.62
Expression of murine leukemia virus envelope glycoprotein gp69/71 on mouse thymocytes. Evidence for two structural variants distinguished by presence vs. absence of GIX antigen. J Exp Med (1975) 1.62
IgD and B cell differentiation. Immunol Rev (1977) 1.59
Clonal analysis of B cells induced to secrete IgG by T cell-derived lymphokine(s). J Exp Med (1984) 1.58
B-cell tolerance. II. Trinitrophenyl human gamma globulin-induced tolerance in adult and neonatal murine B cells responsive to thymus-dependent and independent forms of the same hapten. J Exp Med (1977) 1.57
Cell surface immunoglobulin. XX. Antibody responsiveness of subpopulations of B lymphocytes bearing different isotypes. J Exp Med (1977) 1.57
Lymphokine-induced IgM secretion by clones of neoplastic B cells. Nature (1983) 1.56
Cell surface immunoglobulin. V. Release from murine splenic lymphocytes. J Exp Med (1972) 1.56
The cytophilic activity of human immunoglobulins. J Immunol (1970) 1.55
T cell-derived B cell growth and differentiation factors. Dichotomy between the responsiveness of B cells from adult and neonatal mice. J Exp Med (1983) 1.54
Characterization of the physical interaction between antigen-specific B and T cells. J Immunol (1986) 1.53
Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice. J Neurosci (2001) 1.53
Immunoglobulins, antibodies and the bursa of Fabricus: induction of agammaglobulinemia and the loss of all antibody-forming capacity by hormonal bursectomy. J Immunol (1969) 1.52
Neoplastic B cells as targets for antibody-ricin A chain immunotoxins. Immunol Rev (1982) 1.52
Interleukin 4 mediates autocrine growth of helper T cells after antigenic stimulation. Proc Natl Acad Sci U S A (1986) 1.51
Differential susceptibility of neonatal and adult murine spleen cells to in vitro induction of B-cell tolerance. J Exp Med (1976) 1.50
Antibody formation in dysgammaglobulinemia. J Clin Invest (1966) 1.50
Antibody formation. V. The avidity of gamma-M and gamma-G guinea pig antibodies to bacteriophage phi-x 174. J Immunol (1966) 1.45
Isolation and characterization of H-2 and TL alloantigens from the surface of mouse lymphocytes. Cell Immunol (1972) 1.45
Immunoglobulin synthesis and secretion. VI. Synthesis and intracellular transport of immunoglobulin in nonsecretory lymphoma cells. J Exp Med (1971) 1.45
Epitopes on CD45R [T200] molecules define differentiation antigens on murine B and T lymphocytes. J Mol Cell Immunol (1988) 1.43
Absence of H-2 antigens capable of reacting with cytotoxic T cells on a teratoma line expressing a T/t locus antigen. Proc Natl Acad Sci U S A (1975) 1.43
Structural studies on the murine Ia alloantigens--III. Tryptic peptide comparisons of allelic products of the I-E/C sub-region. Mol Immunol (1979) 1.42
Repetitive nerve stimulation vs. twitch tension in rats with EAMG. Muscle Nerve (1992) 1.40