Published in Infect Immun on May 01, 1980
Construction and characterization of isogenic mutants of Streptococcus mutans deficient in major surface protein antigen P1 (I/II). Infect Immun (1989) 3.06
Streptococcus adherence and colonization. Microbiol Mol Biol Rev (2009) 2.83
Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues. Infect Immun (1989) 2.74
Immunization with purified protein antigens from Streptococcus mutans against dental caries in rhesus monkeys. Infect Immun (1981) 2.72
IgA antibody-producing cells in peripheral blood after antigen ingestion: evidence for a common mucosal immune system in humans. Proc Natl Acad Sci U S A (1987) 2.37
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Surface hydrophobicity, adherence, and aggregation of cell surface protein antigen mutants of Streptococcus mutans serotype c. Infect Immun (1990) 1.95
Local passive immunization by monoclonal antibodies against streptococcal antigen I/II in the prevention of dental caries. Infect Immun (1985) 1.92
Isolation and characterization of monoclonal antibodies specific for antigen P1, a major surface protein of mutans streptococci. Infect Immun (1987) 1.90
Molecular cloning and expression of a Streptococcus mutans major surface protein antigen, P1 (I/II), in Escherichia coli. Infect Immun (1988) 1.88
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Streptococcus mutans genes that code for extracellular proteins in Escherichia coli K-12. Infect Immun (1982) 1.87
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Cloning and expression of a Streptococcus sanguis surface antigen that interacts with a human salivary agglutinin. Infect Immun (1988) 1.75
Salivary, nasal, genital, and systemic antibody responses in monkeys immunized intranasally with a bacterial protein antigen and the Cholera toxin B subunit. Infect Immun (1996) 1.71
Use of monoclonal antibodies in local passive immunization to prevent colonization of human teeth by Streptococcus mutans. Infect Immun (1987) 1.70
Distribution, persistence, and recall of serum and salivary antibody responses to peroral immunization with protein antigen I/II of Streptococcus mutans coupled to the cholera toxin B subunit. Infect Immun (1991) 1.56
A radioimmunoassay for serum and gingival crevicular fluid antibodies to a purified protein of Streptococcus mutans. Clin Exp Immunol (1981) 1.56
Immunoglobulin A subclass distribution of naturally occurring salivary antibodies to microbial antigens. Infect Immun (1985) 1.53
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Sequence and structural analysis of surface protein antigen I/II (SpaA) of Streptococcus sobrinus. Infect Immun (1991) 1.44
Affinity purification and characterization of protease-susceptible antigen I of Streptococcus mutans. Infect Immun (1980) 1.44
Ultrastructural localization of protein antigens I/II and III in Streptococcus mutans. Infect Immun (1983) 1.42
Discrete protein determinant directs the species-specific adherence of Porphyromonas gingivalis to oral streptococci. Infect Immun (2001) 1.41
An investigation into the mechanism of protection by local passive immunization with monoclonal antibodies against Streptococcus mutans. Infect Immun (1990) 1.39
Inhibition of Streptococcus mutans adherence to saliva-coated hydroxyapatite by human secretory immunoglobulin A (S-IgA) antibodies to cell surface protein antigen I/II: reversal by IgA1 protease cleavage. Infect Immun (1992) 1.37
Conservation of the gene encoding streptococcal antigen I/II in oral streptococci. Infect Immun (1991) 1.36
The detection and specificity of class specific antibodies to whole bacterial cells using a solid phase radioimmunoassay. Clin Exp Immunol (1983) 1.31
A protein fragment of streptococcal cell surface antigen I/II which prevents adhesion of Streptococcus mutans. Infect Immun (1993) 1.30
Regions of the Streptococcus sobrinus spaA gene encoding major determinants of antigen I. J Bacteriol (1990) 1.30
The changing faces of Streptococcus antigen I/II polypeptide family adhesins. Mol Microbiol (2010) 1.30
Characterization of monoclonal antibodies to Streptococcus mutans antigenic determinants I/II, I, II, and III and their serotype specificities. Infect Immun (1984) 1.28
Separation and characterization of a subset of human T8+ cells which function as antigen-presenting and contrasuppressor cells. Immunology (1985) 1.28
Elongated fibrillar structure of a streptococcal adhesin assembled by the high-affinity association of alpha- and PPII-helices. Proc Natl Acad Sci U S A (2010) 1.27
Mucosal immunogenicity of a recombinant Salmonella typhimurium-cloned heterologous antigen in the absence or presence of coexpressed cholera toxin A2 and B subunits. Infect Immun (1997) 1.27
Protective salivary immunoglobulin A responses against Streptococcus mutans infection after intranasal immunization with S. mutans antigen I/II coupled to the B subunit of cholera toxin. Infect Immun (1993) 1.25
Mucosal adjuvant properties of mutant LT-IIa and LT-IIb enterotoxins that exhibit altered ganglioside-binding activities. Infect Immun (2005) 1.24
Identification of monoclonal antibody-binding domains within antigen P1 of Streptococcus mutans and cross-reactivity with related surface antigens of oral streptococci. Infect Immun (1991) 1.21
Effective immunity to dental caries: enhancement of salivary anti-Streptococcus mutans antibody responses with oral adjuvants. Infect Immun (1983) 1.20
Restriction fragment length polymorphisms and sequence variation within the spaP gene of Streptococcus mutans serotype c isolates. Infect Immun (1991) 1.19
Role of HtrA in surface protein expression and biofilm formation by Streptococcus mutans. Infect Immun (2005) 1.19
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T-cell, adhesion, and B-cell epitopes of the cell surface Streptococcus mutans protein antigen I/II. Infect Immun (1995) 1.16
Saliva-binding region of Streptococcus mutans surface protein antigen. Infect Immun (1993) 1.15
Development of antibody-secreting cells and antigen-specific T cells in cervical lymph nodes after intranasal immunization. Infect Immun (1997) 1.15
Identification and characterization of an antigen I/II family protein produced by group A Streptococcus. Infect Immun (2006) 1.14
Recognition of carbohydrate and protein epitopes by monoclonal antibodies to a cell wall antigen from Streptococcus mutans. Infect Immun (1987) 1.12
Complete nucleotide sequence of the gene for a surface protein antigen of Streptococcus sobrinus. Infect Immun (1991) 1.12
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Specificity of monoclonal antibodies in local passive immunization against Streptococcus mutans. Clin Exp Immunol (1989) 1.10
Cloning of the saliva-interacting protein gene from Streptococcus mutans. J Bacteriol (1987) 1.07
Lack of antibodies to human heart tissue in sera of rhesus monkeys immunized with Streptococcus mutans antigens and comparative study with rabbit antisera. Infect Immun (1983) 1.07
Oral passive immunization against dental caries in rats by use of hen egg yolk antibodies specific for cell-associated glucosyltransferase of Streptococcus mutans. Infect Immun (1991) 1.05
Active release of bound antibody by Streptococcus mutans. Infect Immun (1995) 1.05
Comparison of an adherence domain and a structural region of Streptococcus mutans antigen I/II in protective immunity against dental caries in rats after intranasal immunization. Infect Immun (1998) 1.04
Specificity of opsonizing antibodies to antigens of Streptococcus mutans. Immunology (1980) 1.04
Identification, purification and characterization of a streptococcal protein antigen with a molecular weight of 3800. Immunology (1983) 1.03
Common antigens of streptococcal and nonstreptococcal oral bacteria: characterization of wall-associated protein and comparison with extracellular protein antigen. Infect Immun (1983) 1.03
Effective immunity to dental caries: gastric intubation of Streptococcus mutans whole cells or cell walls induces protective immunity in gnotobiotic rats. Infect Immun (1983) 1.01
IgA subclasses of human colostral antibodies specific for microbial and food antigens. Clin Exp Immunol (1989) 1.01
Identification and preliminary characterization of saliva-interacting surface antigens of Streptococcus mutans by immunoblotting, ligand blotting, and immunoprecipitation. Infect Immun (1984) 1.01
Identification of antigenic epitopes in an alanine-rich repeating region of a surface protein antigen of Streptococcus mutants. Infect Immun (1993) 1.00
Oral immunization with the saliva-binding region of Streptococcus mutans AgI/II genetically coupled to the cholera toxin B subunit elicits T-helper-cell responses in gut-associated lymphoid tissues. Infect Immun (1997) 1.00
Antigenic characterization of fimbria preparations from Streptococcus mutans isolates from caries-free and caries-susceptible subjects. Clin Diagn Lab Immunol (1997) 1.00
A comparative study of streptococcal antigen-binding human T8+ cells and monocytes, in relation to the HLA-DRw6 locus and the helper, suppressor and contrasuppressor functions. Immunology (1984) 1.00
Oral immunization with recombinant Streptococcus lactis carrying the Streptococcus mutans surface protein antigen gene. Infect Immun (1990) 0.99
Detection and specificity of antibodies secreted by spleen cells in mice immunized with Streptococcus mutans. Infect Immun (1986) 0.97
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Molecular and immunochemical characterization of recombinant Escherichia coli containing the spaA gene region of Streptococcus sobrinus. Infect Immun (1989) 0.96
The role of a human antigen specific T8+ cell subset in antigen presentation, helper function and contrasuppression. Clin Exp Immunol (1985) 0.96
Crystal structure of the C-terminal region of Streptococcus mutans antigen I/II and characterization of salivary agglutinin adherence domains. J Biol Chem (2011) 0.96
In vivo and in vitro adjuvant activities of the B subunit of Type IIb heat-labile enterotoxin (LT-IIb-B5) from Escherichia coli. Vaccine (2009) 0.95
Generation of female genital tract antibody responses by local or central (common) mucosal immunization. Infect Immun (2000) 0.95
The role of MHC class II antigenic determinants in the function of human antigen binding T8+ cells, monocytes and helper and suppressor factors. Clin Exp Immunol (1984) 0.95
Effectiveness of liposomes possessing surface-linked recombinant B subunit of cholera toxin as an oral antigen delivery system. Infect Immun (1998) 0.94
Antigen presentation by a subset of T8+ Ia+ cells to T4+ helper cells. Clin Exp Immunol (1987) 0.93
Characterization of the conformational epitope of Guy's 13, a monoclonal antibody that prevents Streptococcus mutans colonization in humans. Infect Immun (2003) 0.93
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Antibody-secreting cell responses in the mouse liver. Immunology (1992) 0.93
Requirements for surface expression and function of adhesin P1 from Streptococcus mutans. Infect Immun (2008) 0.92
Contribution of the alanine-rich region of Streptococcus mutans P1 to antigenicity, surface expression, and interaction with the proline-rich repeat domain. Infect Immun (2004) 0.92
Binding to gangliosides containing N-acetylneuraminic acid is sufficient to mediate the immunomodulatory properties of the nontoxic mucosal adjuvant LT-IIb(T13I). Clin Vaccine Immunol (2010) 0.91
Cross-reactivity between the immunodominant determinant of the antigen I component of Streptococcus sobrinus SpaA protein and surface antigens from other members of the Streptococcus mutans group. Infect Immun (1990) 0.91
Immunological cross-reactivity between Streptococcus mutans and human heart tissue examined by cross-immunization experiments. Infect Immun (1990) 0.90
Adhesion determinants of the Streptococcus species. Microb Biotechnol (2009) 0.90
Immunochemistry of the Streptococcus mutans BHT cell membrane: detection of determinants cross-reactive with human heart tissue. Infect Immun (1985) 0.90
Unexpectedly high levels of some presumably protective secretory immunoglobulin A antibodies to dental plaque bacteria in salivas of both caries-resistant and caries-susceptible subjects. Infect Immun (1993) 0.90
Characterization of human helper and suppressor factors with special reference to HLA-DR determinants. Immunology (1983) 0.90
Streptococcus sanguis expresses a 150-kilodalton two-domain adhesin: characterization of several independent adhesin epitopes. Infect Immun (1997) 0.90
LT-IIc, a new member of the type II heat-labile enterotoxin family, exhibits potent immunomodulatory properties that are different from those induced by LT-IIa or LT-IIb. Vaccine (2010) 0.89
Characterization of human T8+ suppressor and contrasuppressor cells, separated by the lectin Vicia villosa. Immunology (1988) 0.89
Natural antibodies in man to Streptococcus mutans: specificity and quantification. Immunology (1984) 0.89
Local active gingival immunization by a 3,800-molecular-weight streptococcal antigen in protection against dental caries. Infect Immun (1986) 0.89
Antibody specificity and antigen characterization of rat monoclonal antibodies against Streptococcus mutans cell wall-associated protein antigens. Infect Immun (1985) 0.88
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