Published in Eur J Immunol on January 01, 1985
Crosslinking of surface antigens causes mobilization of intracellular ionized calcium in T lymphocytes. Proc Natl Acad Sci U S A (1987) 2.53
Cholera toxin inhibits the T-cell antigen receptor-mediated increases in inositol trisphosphate and cytoplasmic free calcium. Proc Natl Acad Sci U S A (1986) 1.98
Endocytosis and recycling of the T3-T cell receptor complex. The role of T3 phosphorylation. J Exp Med (1987) 1.80
Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor. Proc Natl Acad Sci U S A (1987) 1.57
Distinct patterns of transmembrane calcium flux and intracellular calcium mobilization after differentiation antigen cluster 2 (E rosette receptor) or 3 (T3) stimulation of human lymphocytes. J Clin Invest (1986) 1.53
Stimulation of T cells through the CD3/T-cell receptor complex: role of cytoplasmic calcium, protein kinase C translocation, and phosphorylation of pp60c-src in the activation pathway. Mol Cell Biol (1987) 1.32
The T-cell antigen receptor regulates sustained increases in cytoplasmic free Ca2+ through extracellular Ca2+ influx and ongoing intracellular Ca2+ mobilization. Biochem J (1987) 1.32
Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events. Proc Natl Acad Sci U S A (1993) 1.21
Different pathways of human T-cell activation revealed by PHA-P and PHA-M. Immunology (1986) 1.16
T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes. Proc Natl Acad Sci U S A (1987) 1.01
Inositol lipid metabolism in human T lymphocytes activated via the T3 complex. Immunology (1987) 0.84
Human T-cell activation: comparative studies on the role of different phorbol esters. Immunology (1988) 0.83
Analysis of isolated and combined effects of calcium ionophore and phorbol ester on T lymphocyte activation. Clin Exp Immunol (1986) 0.81
Two distinct signals regulate induction of IL-2 responsiveness in CD8+ murine T cells. Immunology (1988) 0.80
Characterization of a T-lymphocyte membrane protein involved in T-cell function: its contribution to T-cell recognition or cellular interaction. Immunology (1986) 0.76
Suppress of the increase in free cytosolic calcium during the inhibition of T-cell activation by an autoantibody present in the serum of leprosy patients. Immunology (1989) 0.75
Phenylarsine oxide and phorbol myristate acetate inhibit the CD3-induced rise of cytosolic Ca2+ in Jurkat cells by refilling internal Ca2+ stores. Biochem J (1994) 0.75
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature (1985) 30.47
Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells. J Immunol (1988) 7.37
Distinctive functional characteristics of human "T" lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody. Eur J Immunol (1981) 5.32
Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints. EMBO J (1998) 5.25
Lifespan of human lymphocyte subsets defined by CD45 isoforms. Nature (1992) 4.86
Epitopes of the CD4 antigen and HIV infection. Science (1986) 4.50
Protein antigens of Streptococcus mutans: purification and properties of a double antigen and its protease-resistant component. Infect Immun (1980) 4.36
Ly antigens as markers for functionally distinct subpopulations of thymus-derived lymphocytes of the mouse. Nature (1975) 4.34
Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1. Immunology (1986) 4.00
Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin. J Exp Med (1983) 3.52
Limiting dilution analysis of proliferative responses in human lymphocyte populations defined by the monoclonal antibody UCHL1: implications for differential CD45 expression in T cell memory formation. Eur J Immunol (1988) 3.47
Polymorphism in mitogenic effect of IgG1 monoclonal antibodies against T3 antigen on human T cells. Nature (1983) 3.16
Epithelial cells expressing aberrant MHC class II determinants can present antigen to cloned human T cells. Nature (1985) 3.11
Separation of suppressor and killer T cells by surgace phenotype. Nature (1976) 3.03
Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding. J Exp Med (1990) 3.01
Different Ly antigen phenotypes of in vitro induced helper and suppressor cells. Nature (1975) 2.91
PIB is a non-specific imaging marker of amyloid-beta (Abeta) peptide-related cerebral amyloidosis. Brain (2007) 2.88
Human T-cell clones recognize chemically synthesized peptides of influenza haemagglutinin. Nature (1982) 2.84
Monoclonal antibodies specific for human monocytes, granulocytes and endothelium. Immunology (1984) 2.82
T-cell lines producing antigen-specific suppressor factor. Nature (1978) 2.63
T lymphocytes respond to solid-phase antigen: a novel approach to the molecular analysis of cellular immunity. Immunology (1986) 2.45
Structural model of HLA-DR1 restricted T cell antigen recognition. Cell (1988) 2.41
The human and simian immunodeficiency viruses HIV-1, HIV-2 and SIV interact with similar epitopes on their cellular receptor, the CD4 molecule. AIDS (1988) 2.35
The monoclonal antibody, UCHL1, recognizes a 180,000 MW component of the human leucocyte-common antigen, CD45. Immunology (1988) 2.32
Antigen-specific human T lymphocyte clones: induction, antigen specificity, and MHC restriction of influenza virus-immune clones. J Immunol (1982) 2.30
Risk of second malignancy after Hodgkin's disease in a collaborative British cohort: the relation to age at treatment. J Clin Oncol (2000) 2.29
Monoclonal antibody (UCHL1) that recognises normal and neoplastic T cells in routinely fixed tissues. J Clin Pathol (1986) 2.24
T-T interactions in the induction of suppressor and helper T cells: analysis of membrane phenotype of precursor and amplifier cells. J Exp Med (1977) 2.22
Amplification of mitochondrial DNA in acute myeloid leukaemia. Br J Haematol (1996) 2.17
Tolerance of T-cell clones is associated with membrane antigen changes. Nature (1983) 2.10
Mapping of T cell epitopes using recombinant antigens and synthetic peptides. EMBO J (1987) 2.09
Randomised trial of filgrastim-mobilised peripheral blood progenitor cell transplantation versus autologous bone-marrow transplantation in lymphoma patients. Lancet (1996) 2.06
Biological activity of protein antigens isolated from Mycobacterium tuberculosis culture filtrate. Infect Immun (1988) 2.01
A large proportion of patients with a diagnosis of essential thrombocythemia do not have a clonal disorder and may be at lower risk of thrombotic complications. Blood (1999) 1.97
In vivo CAMPATH-1H prevents graft-versus-host disease following nonmyeloablative stem cell transplantation. Blood (2000) 1.93
Characterization of the two heavy chains of the T3 complex on the surface of human T lymphocytes. J Biol Chem (1984) 1.93
Phytohaemagglutinin activation of T cells through the sheep red blood cell receptor. Nature (1985) 1.89
Analysis of the antigen specificity of influenza haemagglutinin-immune human T lymphocyte clones: identification of an immunodominant region for T cells. Immunology (1983) 1.88
Monoclonal antibodies against human T lymphocytes label Purkinje neurones of many species. Nature (1982) 1.85
Neural cell adhesion molecule (NCAM) is the antigen recognized by monoclonal antibodies of similar specificity in small-cell lung carcinoma and neuroblastoma. Int J Cancer (1989) 1.85
HIV infection of primate lymphocytes and conservation of the CD4 receptor. Nature (1988) 1.84
Acquired skewing of X-chromosome inactivation patterns in myeloid cells of the elderly suggests stochastic clonal loss with age. Br J Haematol (1997) 1.83
Long-term effect of a watch and wait policy versus immediate systemic treatment for asymptomatic advanced-stage non-Hodgkin lymphoma: a randomised controlled trial. Lancet (2003) 1.80
Binary and ternary complexes between T-cell receptor, class II MHC and superantigen in vitro. Nature (1994) 1.79
Evidence for differential expression of CD45 isoforms by precursors for memory-dependent and independent cytotoxic responses: human CD8 memory CTLp selectively express CD45RO (UCHL1). Int Immunol (1989) 1.77
Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4+ T cells. J Immunol (1999) 1.77
Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice. J Exp Med (1993) 1.71
Development of antibodies to unprotected glycosylation sites on recombinant human GM-CSF. Lancet (1990) 1.71
Two monoclonal anti-human T lymphocyte antibodies have similar biologic effects and recognize the same cell surface antigen. J Immunol (1982) 1.68
Phenotypic changes associated with activation of CD45RA+ and CD45RO+ T cells. Immunology (1990) 1.66
Which guesstimate is the best guesstimate? Predicting chemotherapeutic outcomes. Nat Med (1997) 1.66
A novel approach to the identification of T-cell epitopes in Mycobacterium tuberculosis using human T-lymphocyte clones. Immunology (1987) 1.63
PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways. Leukemia (2005) 1.61
T-cell clonality in immune responses. Immunol Today (1999) 1.61
Structural analysis of the human immunodeficiency virus-binding domain of CD4. Epitope mapping with site-directed mutants and anti-idiotypes. J Exp Med (1989) 1.60
Fc receptors for mouse IgG1 on human monocytes: polymorphism and role in antibody-induced T cell proliferation. J Immunol (1984) 1.59
Molecular cloning and tissue expression of FAT, the human homologue of the Drosophila fat gene that is located on chromosome 4q34-q35 and encodes a putative adhesion molecule. Genomics (1995) 1.59
Isolation of human haematopoietic progenitor cells using monoclonal antibodies. Nature (1980) 1.57
The CD20 (Bp35) antigen is involved in activation of B cells from the G0 to the G1 phase of the cell cycle. J Immunol (1985) 1.57
Impaired production of interleukins in patients with cell-mediated immunodeficiencies. Clin Exp Immunol (1983) 1.55
The place of high-dose BEAM therapy and autologous bone marrow transplantation in poor-risk Hodgkin's disease. A single-center eight-year study of 155 patients. Blood (1993) 1.55
Augmentation of fetal-hemoglobin production in anemic monkeys by hydroxyurea. N Engl J Med (1984) 1.54
A human suppressor T cell clone which recognizes an autologous helper T cell clone. Nature (1982) 1.54
Human T cell subsets. Immunol Lett (1987) 1.53
The tissue distribution of T lymphocytes expressing different CD45 polypeptides. Immunology (1989) 1.52
TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor prognosis. Leukemia (2008) 1.50
Ly antigens: markers of T cell function on mouse spleen cells. J Immunol (1975) 1.49
Antigen-specific human T lymphocyte clones: viral antigen specificity of influenza virus-immune clones. J Immunol (1982) 1.49
T cell activation by anti-T3 antibodies: comparison of IgG1 and IgG2b switch variants and direct evidence for accessory function of macrophage Fc receptors. Eur J Immunol (1986) 1.49
Human macrophage colony-stimulating factor levels are elevated in pregnancy and in immune thrombocytopenia. Blood (1992) 1.49
Evidence for an extra-chromosomal element involved in mitochondrial function: a mitochondrial episome? FEBS Lett (1975) 1.48
Interleukin-2 can prevent and reverse antigen-induced unresponsiveness in cloned human T lymphocytes. Immunology (1988) 1.48
Fc gamma RII, but not erythropoietin or GM-CSF, mediates calcium mobilization in fetal hemopoietic blast cells. Exp Hematol (1992) 1.45
Cushing's syndrome--killing disease: discriminatory value of signs and symptoms aiding early diagnosis. Lancet (1982) 1.45
Separation and characterization of a protein antigen from cells of Streptococcus mutans. J Gen Microbiol (1981) 1.44
Affinity purification and characterization of protease-susceptible antigen I of Streptococcus mutans. Infect Immun (1980) 1.44
Lack of effect of granulocyte-macrophage and granulocyte colony-stimulating factors on cultured human endothelial cells. Blood (1991) 1.43
Ontogeny of expression of UCHL1 antigen on TcR-1+ (CD4/8) and TcR delta+ T cells. Eur J Immunol (1989) 1.42
Incidence and mechanism of neutropenia and thrombocytopenia in patients with human immunodeficiency virus infection. Br J Haematol (1987) 1.42
The distribution of CD45R, CD29 and CD45RO (UCHL1) antigens in mature CD4 positive T-cell leukaemias. Br J Haematol (1990) 1.41
Lymphopenia in diverticulitis. Lancet (1991) 1.41
Induction of a type 1 immune response to a recombinant antigen from Mycobacterium tuberculosis expressed in Mycobacterium vaccae. Infect Immun (1997) 1.41
X-chromosome inactivation patterns using HPRT and PGK polymorphisms in haematologically normal and post-chemotherapy females. Br J Haematol (1991) 1.39
Acute-phase response in patients given rhIL-3 after chemotherapy. Lancet (1992) 1.39
The natural history of lymphocyte subsets infiltrating the pancreas of NOD mice. Diabetologia (1989) 1.38
Major histocompatibility complex independent clonal T cell anergy by direct interaction of Staphylococcus aureus enterotoxin B with the T cell antigen receptor. J Exp Med (1992) 1.37
Tissue specificity of X-chromosome inactivation patterns. Blood (1994) 1.37
Prevention of venous thromboembolism after total knee replacement by high-dose aspirin or intermittent calf and thigh compression. Br Med J (1980) 1.37
An immunohistological study of secondary Sjögren's syndrome. Ann Rheum Dis (1984) 1.36
Unusual phenotype and function of an expanded subpopulation of T cells in patients with haemopoietic disorders. Clin Exp Immunol (1981) 1.35
Evidence for a superantigen mediated process in Kawasaki disease. Arch Dis Child (1995) 1.34
A deletion in the gene encoding the CD45 antigen in a patient with SCID. J Immunol (2001) 1.34