Published in Nature on February 26, 1981
Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles. Microbiol Rev (1983) 24.58
The tac promoter: a functional hybrid derived from the trp and lac promoters. Proc Natl Acad Sci U S A (1983) 9.95
Nucleotide sequence and functional map of pE194, a plasmid that specifies inducible resistance to macrolide, lincosamide, and streptogramin type B antibodies. J Bacteriol (1982) 9.02
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Metabolic repression of transcription in higher plants. Plant Cell (1990) 6.21
The complete nucleotide sequence of the tryptophan operon of Escherichia coli. Nucleic Acids Res (1981) 5.91
Comparison of intron-dependent and intron-independent gene expression. Mol Cell Biol (1988) 4.75
A computer algorithm for testing potential prokaryotic terminators. Nucleic Acids Res (1984) 4.73
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Novel form of transcription attenuation regulates expression the Bacillus subtilis tryptophan operon. J Bacteriol (1986) 3.90
Cooperation between translating ribosomes and RNA polymerase in transcription elongation. Science (2010) 3.87
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The nucleotide sequence of tobacco vein mottling virus RNA. Nucleic Acids Res (1986) 3.33
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Nucleotide sequence of the ilvB promoter-regulatory region: a biosynthetic operon controlled by attenuation and cyclic AMP. Proc Natl Acad Sci U S A (1982) 2.50
Influence of the codon following the AUG initiation codon on the expression of a modified lacZ gene in Escherichia coli. EMBO J (1987) 2.46
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Actinomycin and DNA transcription. Proc Natl Acad Sci U S A (1985) 2.45
Attenuation control of pyrBI operon expression in Escherichia coli K-12. Proc Natl Acad Sci U S A (1983) 2.39
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Transcription of the Escherichia coli fumarate reductase genes (frdABCD) and their coordinate regulation by oxygen, nitrate, and fumarate. J Bacteriol (1985) 2.24
Transcription termination occurs within a 1000 base pair region downstream from the poly(A) site of the mouse beta-globin (major) gene. Nucleic Acids Res (1984) 2.24
Evolution in biosynthetic pathways: two enzymes catalyzing consecutive steps in methionine biosynthesis originate from a common ancestor and possess a similar regulatory region. Proc Natl Acad Sci U S A (1986) 2.21
Tandem termination sites in the tryptophan operon of Escherichia coli. Proc Natl Acad Sci U S A (1981) 2.19
Evidence for transcription antitermination control of tryptophanase operon expression in Escherichia coli K-12. J Bacteriol (1985) 2.19
Synthesis of calf prochymosin (prorennin) in Escherichia coli. Proc Natl Acad Sci U S A (1983) 2.13
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Pausing and premature termination of human RNA polymerase II during transcription of adenovirus in vivo and in vitro. Proc Natl Acad Sci U S A (1984) 2.08
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Mechanism for iron-regulated transcription of the Escherichia coli cir gene: metal-dependent binding of fur protein to the promoters. J Bacteriol (1989) 1.93
Mechanism of sequence-specific pausing of bacterial RNA polymerase. Proc Natl Acad Sci U S A (2009) 1.92
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The nucleotide sequence of aroG, the gene for 3-deoxy-D-arabinoheptulosonate-7-phosphate synthetase (phe) in Escherichia coli K12. Nucleic Acids Res (1982) 1.82
Regulation of Escherichia coli aspartate transcarbamylase synthesis by guanosine tetraphosphate and pyrimidine ribonucleoside triphosphates. J Bacteriol (1983) 1.81
Transcription initiation at the tryptophanase promoter of Escherichia coli K-12. J Bacteriol (1982) 1.80
Engineering biological systems with synthetic RNA molecules. Mol Cell (2011) 1.80
The serC-aro A operon of Escherichia coli. A mixed function operon encoding enzymes from two different amino acid biosynthetic pathways. Biochem J (1986) 1.75
How the phage lambda N gene product suppresses transcription termination: communication of RNA polymerase with regulatory proteins mediated by signals in nascent RNA. J Bacteriol (1992) 1.71
An aminoacyl-tRNA synthetase paralog with a catalytic role in histidine biosynthesis. Proc Natl Acad Sci U S A (1999) 1.71
Repression is relieved before attenuation in the trp operon of Escherichia coli as tryptophan starvation becomes increasingly severe. J Bacteriol (1984) 1.70
Identification of two genes immediately downstream from the polA gene of Escherichia coli. J Bacteriol (1982) 1.68
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Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation. EMBO J (1987) 1.60
The regulatory region of the divergent argECBH operon in Escherichia coli K-12. Nucleic Acids Res (1982) 1.60
Translation activates the paused transcription complex and restores transcription of the trp operon leader region. Proc Natl Acad Sci U S A (1985) 1.59
RNA misfolding and the action of chaperones. Front Biosci (2008) 1.59
Termination and antitermination: RNA polymerase runs a stop sign. Nat Rev Microbiol (2011) 1.59
Regulation of pyrimidine biosynthetic gene expression in bacteria: repression without repressors. Microbiol Mol Biol Rev (2008) 1.57
Regulation of phenylalanine biosynthesis in Escherichia coli K-12: control of transcription of the pheA operon. J Bacteriol (1982) 1.57
Transcription attenuation: once viewed as a novel regulatory strategy. J Bacteriol (2000) 1.56
Quantities of individual aminoacyl-tRNA families and their turnover in Escherichia coli. J Bacteriol (1984) 1.56
The influence of messenger RNA secondary structure on expression of an immunoglobulin heavy chain in Escherichia coli. Nucleic Acids Res (1984) 1.56
Characterization of the Bacillus subtilis tryptophan promoter region. Proc Natl Acad Sci U S A (1984) 1.55
Nucleotide sequence of metF, the E. coli structural gene for 5-10 methylene tetrahydrofolate reductase and of its control region. Nucleic Acids Res (1983) 1.53
Overlapping open reading frames revealed by complete nucleotide sequencing of turnip yellow mosaic virus genomic RNA. Nucleic Acids Res (1988) 1.52
Structural and transcriptional evidence for related thrS and infC expression. Proc Natl Acad Sci U S A (1983) 1.51
Synthesis of aspartate transcarbamoylase in Escherichia coli: transcriptional regulation of the pyrB-pyrI operon. Proc Natl Acad Sci U S A (1983) 1.50
Regulation of expression of the Pasteurella haemolytica leukotoxin determinant. J Bacteriol (1989) 1.45
Attenuation of late simian virus 40 mRNA synthesis is enhanced by the agnoprotein and is temporally regulated in isolated nuclear systems. Mol Cell Biol (1985) 1.43
Translational requirement of La Crosse virus S-mRNA synthesis: in vitro studies. J Virol (1987) 1.43
Homologous control sites and DNA transcription starts in the related argF and argI genes of Escherichia coli K12. EMBO J (1982) 1.43
Transcription terminates at lambda tR1 in three clusters. Proc Natl Acad Sci U S A (1982) 1.42
Nucleotide sequences of two serine tRNAs with a GGA anticodon: the structure-function relationships in the serine family of E. coli tRNAs. Nucleic Acids Res (1985) 1.41
Nucleotide sequence of the ilvB multivalent attenuator region of Escherichia coli K12. Nucleic Acids Res (1983) 1.40
Molecular analysis of a pathogenicity locus in Pseudomonas syringae pv. syringae. J Bacteriol (1988) 1.40
Transcription unit of the rabbit beta 1 globin gene. Mol Cell Biol (1985) 1.40
Bacterial transcriptomics: what is beyond the RNA horiz-ome? Nat Rev Microbiol (2011) 1.39
A Bacillus subtilis operon containing genes of unknown function senses tRNATrp charging and regulates expression of the genes of tryptophan biosynthesis. Proc Natl Acad Sci U S A (2000) 1.38
Iron mediated methylthiolation of tRNA as a regulator of operon expression in Escherichia coli. Nucleic Acids Res (1982) 1.38
Cloning and characterization of the gene for Escherichia coli tryptophanyl-transfer ribonucleic acid synthetase. J Bacteriol (1981) 1.38
Nucleotide sequence of the asd gene of Escherichia coli: absence of a typical attenuation signal. EMBO J (1982) 1.38
Differential mRNA stability controls relative gene expression within the plasmid-encoded arsenical resistance operon. J Bacteriol (1990) 1.37
Sequence for human argininosuccinate synthetase cDNA. Nucleic Acids Res (1983) 1.36
Indigo formation by microorganisms expressing styrene monooxygenase activity. Appl Environ Microbiol (1997) 1.35
Nucleotide sequence of bean golden mosaic virus and a model for gene regulation in geminiviruses. Proc Natl Acad Sci U S A (1985) 1.35
Attenuation in SV40 as a mechanism of transcription-termination by RNA polymerase B. Nucleic Acids Res (1984) 1.35
A high resolution map of a cyanobacterial transcriptome. Genome Biol (2011) 1.35
Bacteriophage T7 RNA polymerase travels far ahead of ribosomes in vivo. J Bacteriol (1992) 1.35
Translational requirement for La Crosse virus S-mRNA synthesis: a possible mechanism. J Virol (1987) 1.34
Transcription termination at the tryptophan operon attenuator is decreased in vitro by an oligomer complementary to a segment of the leader transcript. Proc Natl Acad Sci U S A (1982) 1.31
Premature termination by human RNA polymerase II occurs temporally in the adenovirus major late transcriptional unit. Mol Cell Biol (1984) 1.30
Promoter domain mediates guanosine tetraphosphate activation of the histidine operon. Proc Natl Acad Sci U S A (1986) 1.30
Tn9 and IS1 inserts in a ribosomal ribonucleic acid operon of Escherichia coli are incompletely polar. J Bacteriol (1981) 1.29
The TRP4 gene of Saccharomyces cerevisiae: isolation and structural analysis. Nucleic Acids Res (1986) 1.28
ArgR and AhrC are both required for regulation of arginine metabolism in Lactococcus lactis. J Bacteriol (2004) 1.27
A cis-acting repressive sequence that overlaps the Rev-responsive element of human immunodeficiency virus type 1 regulates nuclear retention of env mRNAs independently of known splice signals. Proc Natl Acad Sci U S A (1994) 1.26
Entropy-based mechanism of ribosome-nucleoid segregation in E. coli cells. Biophys J (2011) 1.24
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The complete nucleotide sequence of the tryptophan operon of Escherichia coli. Nucleic Acids Res (1981) 5.91
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Translational coupling during expression of the tryptophan operon of Escherichia coli. Genetics (1980) 5.57
New features of the regulation of the tryptophan operon. Science (1975) 5.40
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An electrophoretic karyotype of Neurospora crassa. Mol Cell Biol (1988) 4.46
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The unusual mutagenic specificity of an E. Coli mutator gene. Proc Natl Acad Sci U S A (1966) 4.26
Regulated in vitro synthesis of Escherichia coli tryptophan operon messenger ribonucleic acid and enzymes. J Biol Chem (1974) 4.25
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An intercistronic region and ribosome-binding site in bacterial messenger RNA. Proc Natl Acad Sci U S A (1975) 3.95
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Nucleotide sequences of trpA of Salmonella typhimurium and Escherichia coli: an evolutionary comparison. Proc Natl Acad Sci U S A (1979) 3.87
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Nucleotide sequence of the structural gene for tryptophanase of Escherichia coli K-12. J Bacteriol (1981) 2.91
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