Published in Trans R Soc Trop Med Hyg on January 01, 1981
Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. Proc Natl Acad Sci U S A (1988) 5.92
Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil. Proc Natl Acad Sci U S A (1997) 5.75
Mutations in Plasmodium falciparum cytochrome b that are associated with atovaquone resistance are located at a putative drug-binding site. Antimicrob Agents Chemother (2000) 3.58
Polymorphism of a high molecular weight schizont antigen of the human malaria parasite Plasmodium falciparum. J Exp Med (1985) 2.15
Polymorphism of the precursor for the major surface antigens of Plasmodium falciparum merozoites: studies at the genetic level. EMBO J (1985) 1.69
A malaria protein exported into a new compartment within the host erythrocyte. EMBO J (1987) 1.49
Cloning and characterisation of the rRNA genes from the human malaria parasite Plasmodium falciparum. Nucleic Acids Res (1983) 1.47
Validation of the hexose transporter of Plasmodium falciparum as a novel drug target. Proc Natl Acad Sci U S A (2003) 1.38
Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo. Infect Immun (2006) 1.37
Comparative transcriptional and genomic analysis of Plasmodium falciparum field isolates. PLoS Pathog (2009) 1.24
Antigenic differences among isolates of Plasmodium falciparum demonstrated by monoclonal antibodies. Infect Immun (1982) 1.22
The gene for an exported antigen of the malaria parasite Plasmodium falciparum cloned and expressed in Escherichia coli. Nucleic Acids Res (1985) 1.18
An improved and highly sensitive microfluorimetric method for assessing susceptibility of Plasmodium falciparum to antimalarial drugs in vitro. Malar J (2006) 1.16
A framework for assessing the risk of resistance for anti-malarials in development. Malar J (2012) 1.09
First assessment in humans of the safety, tolerability, pharmacokinetics, and ex vivo pharmacodynamic antimalarial activity of the new artemisinin derivative artemisone. Antimicrob Agents Chemother (2008) 1.07
Targeting of hematin by the antimalarial pyronaridine. Antimicrob Agents Chemother (2006) 1.02
Plasmodium falciparum merozoite surface protein 6 is a dimorphic antigen. Infect Immun (2004) 1.00
Culture-adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers. Malar J (2013) 1.00
DNA polymerase delta: gene sequences from Plasmodium falciparum indicate that this enzyme is more highly conserved than DNA polymerase alpha. Nucleic Acids Res (1991) 0.98
Clones of different sensitivities in drug-resistant isolates of Plasmodium falciparum. Bull World Health Organ (1983) 0.93
Antiprotozoal activities of organic extracts from French marine seaweeds. Mar Drugs (2011) 0.92
Removal of heterologous sequences from Plasmodium falciparum mutants using FLPe-recombinase. PLoS One (2010) 0.90
Antigenicity of recombinant proteins derived from rhoptry-associated protein 1 of Plasmodium falciparum. Infect Immun (1998) 0.88
Development of halofantrine resistance and determination of cross-resistance patterns in Plasmodium falciparum. Antimicrob Agents Chemother (1993) 0.87
Antimalarial 9-anilinoacridine compounds directed at hematin. Antimicrob Agents Chemother (2003) 0.87
Rhoptry-associated protein 1-binding monoclonal antibody raised against a heterologous peptide sequence inhibits Plasmodium falciparum growth in vitro. Infect Immun (2001) 0.85
The gene encoding DNA polymerase alpha from Plasmodium falciparum. Nucleic Acids Res (1993) 0.81
In vitro activities of the biguanide PS-15 and its metabolite, WR99210, against cycloguanil-resistant Plasmodium falciparum isolates from Thailand. Antimicrob Agents Chemother (1997) 0.80
The gene encoding topoisomerase II from Plasmodium falciparum. Nucleic Acids Res (1994) 0.79
Molecular cloning of a Plasmodium falciparum gene interrupted by 15 introns encoding a functional primase 53 kDa subunit as demonstrated by expression in a baculovirus system. Nucleic Acids Res (1996) 0.78
New quinoline di-Mannich base compounds with greater antimalarial activity than chloroquine, amodiaquine, or pyronaridine. Antimicrob Agents Chemother (1997) 0.76
Eleganolone, a diterpene from the French marine alga Bifurcaria bifurcata inhibits growth of the human pathogens Trypanosoma brucei and Plasmodium falciparum. Mar Drugs (2013) 0.75
Analysis of P-glycoprotein expression in purified parasite plasma membrane and food vacuole from Plasmodium falciparum. Parasitol Res (2006) 0.75
High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction. Mol Biochem Parasitol (1993) 17.06
Identification of the four human malaria parasite species in field samples by the polymerase chain reaction and detection of a high prevalence of mixed infections. Mol Biochem Parasitol (1993) 8.43
Biased distribution of msp1 and msp2 allelic variants in Plasmodium falciparum populations in Thailand. Trans R Soc Trop Med Hyg (2000) 7.93
Amplification of pfmdr 1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand. Mol Biochem Parasitol (1993) 3.16
Genotyping of Plasmodium falciparum isolates by the polymerase chain reaction and potential uses in epidemiological studies. Bull World Health Organ (1995) 2.00
4-aminoquinoline analogs of chloroquine with shortened side chains retain activity against chloroquine-resistant Plasmodium falciparum. Antimicrob Agents Chemother (1996) 1.65
Clonal diversity in a single isolate of the malaria parasite Plasmodium falciparum. Trans R Soc Trop Med Hyg (1984) 1.63
Susceptibility of Plasmodium falciparum to five drugs: an in vitro study of isolates mainly from Thailand. Trans R Soc Trop Med Hyg (1983) 1.34
Interallelic recombination in the merozoite surface protein 1 (MSP-1) gene of Plasmodium vivax from Thai isolates. Mol Biochem Parasitol (1997) 1.24
Mitochondrial genetics in Paramecium. Nature (1972) 1.24
Persistence of drug-resistant malaria parasites. Lancet (1978) 1.21
Genetic diversity of Plasmodium falciparum shows geographical variation. Am J Trop Med Hyg (1990) 1.18
Immunomagnetic purification to facilitate DNA diagnosis of Plasmodium falciparum. J Clin Microbiol (1993) 1.14
Susceptibility of Thai isolates of Plasmodium falciparum to artemisinine (qinghaosu) and artemether. Bull World Health Organ (1985) 1.13
Cloning and characterization of mefloquine-resistant Plasmodium falciparum from Thailand. Am J Trop Med Hyg (1985) 1.11
Cytoadherence characteristics of rosette-forming Plasmodium falciparum. Infect Immun (1992) 1.05
Plasmodium falciparum: gene mutations and amplification of dihydrofolate reductase genes in parasites grown in vitro in presence of pyrimethamine. Exp Parasitol (2001) 1.04
A note on the inheritance of erythromycin-resistance in Paramecium aurelia. Genet Res (1969) 1.04
An integrated system using immunomagnetic separation, polymerase chain reaction, and colorimetric detection for diagnosis of Plasmodium falciparum. Am J Trop Med Hyg (1997) 1.03
Flow cytometric screening of blood samples for malaria parasites. Cytometry (1993) 0.99
Enzyme typing of some isolates of Plasmodium falciparum from Thailand. Trans R Soc Trop Med Hyg (1981) 0.94
Epidemiological studies of malaria at Pong Nam Ron, eastern Thailand. Southeast Asian J Trop Med Public Health (1994) 0.94
Clones of different sensitivities in drug-resistant isolates of Plasmodium falciparum. Bull World Health Organ (1983) 0.93
Flow cytometric assessment of hydroxypyridinone iron chelators on in vitro growth of drug-resistant malaria. Cytometry (1997) 0.90
Interspecies transfer of mitochondria in Paramecium aurelia. Mol Gen Genet (1976) 0.89
Differentiation of Plasmodium falciparum clones by means of a repetitive DNA probe. Trans R Soc Trop Med Hyg (1988) 0.89
Automated flow cytometric analysis of drug susceptibility of malaria parasites. Am J Trop Med Hyg (1990) 0.87
Three different types of mate-killer (mu) particle in Paramecium aurelia (syngen 1). J Cell Sci (1966) 0.87
The genetics of drug resistance in malaria parasites. Bull World Health Organ (1980) 0.86
Alterations in membrane proteins of mouse erythrocytes infected with different species and strains of malaria parasites. Comp Biochem Physiol B (1979) 0.86
Mitochondrial mutations affecting resistance to erythromycin and mikamycin in Paramecium aurelia: provisional results with a new method. Genet Res (1974) 0.82
Culturing Plasmodium falciparum from finger-prick samples of infected blood. Trans R Soc Trop Med Hyg (1995) 0.81
Evidence of increased chloroquine sensitivity in Thai isolates of Plasmodium falciparum. Trans R Soc Trop Med Hyg (1988) 0.80
Seroepidemiologic studies of humoral immune response to the Plasmodium falciparum antigens in Thailand. Am J Trop Med Hyg (1992) 0.80
Genetic studies on mitochondrially inherited mikamycin-resistance in Paramecium aurelia. Mol Gen Genet (1973) 0.79
Human behavior in relation to selection of malaria treatment. Southeast Asian J Trop Med Public Health (1992) 0.78
Malaria in a rural area of eastern Thailand: baseline epidemiological studies at Bo Thong. Southeast Asian J Trop Med Public Health (1992) 0.78
Some additional results on the maintenance of kappa particles in Paramecium aurelia (stock 51) after loss of the gene K. Genet Res (1967) 0.78
Variability in drug susceptibility amongst clones and isolates of Plasmodium falciparum. Trans R Soc Trop Med Hyg (1988) 0.77
The role of the cytoplasm in heredity. Proc R Soc Lond B Biol Sci (1966) 0.76
Polymorphism of proteins in malaria parasites following mefloquine treatment. Mol Biochem Parasitol (1987) 0.76
The variation of Pf155/RESA gene in field isolates of Plasmodium falciparum from Thailand. J Med Assoc Thai (1996) 0.75
Electrophoretic variants of enzymes in isolates of Plasmodium falciparum, P. malariae and P. vivax from Thailand. Trans R Soc Trop Med Hyg (1990) 0.75
Comparison of bacterial and other extrachromosomal genetic elements. J Gen Microbiol (1969) 0.75
Isolation of clones of Plasmodium falciparum by micromanipulation. Trans R Soc Trop Med Hyg (1991) 0.75
Ciliated protozoa. J Gen Microbiol (1968) 0.75
Electrophoretic analysis of a natural population of the Thai Paragonimus heterotremus and its genetic relationship to the three Japanese species P. miyazaki, P. ohirai and P. westermani. Parasitol Res (1992) 0.75
The Leeuwenhoek lecture, 1976: protozoa and genetics. Proc R Soc Lond B Biol Sci (1977) 0.75
Erythromycin binding studies on two different classes of antibiotic resistant mutant in Paramecium. FEBS Lett (1975) 0.75
[Genotyping of Plasmodium falciparum isolates by amplification of glutamate-rich protein gene using polymerase chain reaction]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi (1998) 0.75
Antiparasite adherence activity in Thai individuals living in a P. falciparum endemic area. Asian Pac J Allergy Immunol (1999) 0.75
Lymphocyte responses to Plasmodium falciparum ring-infected erythrocyte surface antigen (Pf155/RESA) peptides in individuals with naturally acquired Plasmodium falciparum malaria. Am J Trop Med Hyg (1994) 0.75
Surface ultrastructure of newly excysted metacercariae of Paragonimus heterotremus. Southeast Asian J Trop Med Public Health (1990) 0.75