Published in Vox Sang on January 01, 1982
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature (1984) 17.70
The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet (2012) 17.29
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature (1985) 13.79
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science (1985) 9.12
Construction and fine mapping of recombinant plasmids containing the rrnB ribosomal RNA operon of E. coli. Plasmid (1981) 9.00
The economic burden of back pain in the UK. Pain (2000) 6.79
Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J (1986) 6.62
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. Nature (1998) 6.49
Current cost of medical negligence in NHS hospitals: analysis of claims database. BMJ (2000) 4.25
Randomised controlled trial comparing hospital at home care with inpatient hospital care. I: three month follow up of health outcomes. BMJ (1998) 3.82
Isolation of the human insulin-like growth factor I gene using a single synthetic DNA probe. EMBO J (1984) 3.74
Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin. Proc Natl Acad Sci U S A (1992) 3.72
Nucleotide sequence of epidermal growth factor cDNA predicts a 128,000-molecular weight protein precursor. Nature (1983) 3.43
Randomised controlled trial of laparoscopic versus open repair of inguinal hernia: early results. BMJ (1995) 3.37
Randomised controlled trial comparing hospital at home care with inpatient hospital care. II: cost minimisation analysis. BMJ (1998) 3.21
The future of general medicine: lessons from an admissions ward. J R Coll Physicians Lond (1998) 3.19
Human beta-nerve growth factor gene sequence highly homologous to that of mouse. Nature (1983) 3.17
Genetic variation in the human insulin gene. Science (1980) 3.13
Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1. Biochem J (1999) 3.03
The distribution of health care costs and their statistical analysis for economic evaluation. J Health Serv Res Policy (1998) 2.94
The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor. EMBO J (1984) 2.77
Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4. Proc Natl Acad Sci U S A (1996) 2.77
Randomised controlled trial of an interactive multimedia decision aid on benign prostatic hypertrophy in primary care. BMJ (2001) 2.71
The platelet function defect of cardiopulmonary bypass. Blood (1993) 2.63
A randomised controlled trial and cost analysis of problem-solving treatment for emotional disorders given by community nurses in primary care. Br J Psychiatry (1997) 2.56
Insulin-like growth factor II precursor gene organization in relation to insulin gene family. Nature (1984) 2.53
Measuring the impact of menopausal symptoms on quality of life. BMJ (1993) 2.42
Serum concentration measurements in man of the radiosensitizer Ro-07-0582: some preliminary results. Br J Cancer (1975) 2.39
The use of out of hours health services: a cross sectional survey. BMJ (1998) 2.36
Randomised controlled trial of an interactive multimedia decision aid on hormone replacement therapy in primary care. BMJ (2001) 2.30
Effect of colesevelam on faecal bile acids and bowel functions in diarrhoea-predominant irritable bowel syndrome. Aliment Pharmacol Ther (2015) 2.13
HRT: an analysis of benefits, risks and costs. Br Med Bull (1992) 2.11
Cost of poor adherence to anti-hypertensive therapy in five European countries. Eur J Health Econ (2014) 2.06
Segregation at a locus determining an immunoglobulin genetic marker for the light chain variable region affects inheritance of expression of an idiotype. Proc Natl Acad Sci U S A (1977) 1.97
Size dependent platelet subpopulations: relationship of platelet volume to ultrastructure, enzymatic activity, and function. Br J Haematol (1982) 1.96
Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. J Am Coll Cardiol (1998) 1.95
Does erythrocyte infusion improve 3.2-km run performance at high altitude? Eur J Appl Physiol Occup Physiol (1998) 1.94
Relation between recurrence of cancer of the colon and blood transfusion. Br Med J (Clin Res Ed) (1985) 1.91
In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proc Natl Acad Sci U S A (1996) 1.90
Electrical alternans and cardiac electrical instability. Circulation (1988) 1.86
Excretion of deoxyribonucleic acid by lymphocytes stimulated with phytohemagglutinin or antigen. Proc Natl Acad Sci U S A (1972) 1.84
Nucleotide sequence of human preproinsulin complementary DNA. Science (1980) 1.80
The economic burden of coronary heart disease in the UK. Heart (2002) 1.78
Postischemic renal injury is mediated by neutrophils and leukotrienes. Am J Physiol (1989) 1.77
Cost of cardiovascular diseases in the United Kingdom. Heart (2006) 1.70
Automated hemagglutination assays. Ann N Y Acad Sci (1965) 1.68
Frequency of occurrence of idiotypes associated with anti-p-azophenylarsonate antibodies arising in mice immunologically suppressed with respect to a cross-reactive idiotype. J Exp Med (1977) 1.67
Reversible inhibition of human platelet activation by hypothermia in vivo and in vitro. Thromb Haemost (1994) 1.66
Differential signalling potential of insulin- and IGF-1-receptor cytoplasmic domains. EMBO J (1989) 1.64
Isolation of a cDNA clone coding for the gamma-subunit of mouse nerve growth factor using a high-stringency selection procedure. DNA (1984) 1.64
Fibrinogen. Int J Biochem Cell Biol (1999) 1.57
Pathophysiology of ischaemia reperfusion injury: central role of the neutrophil. Br J Surg (1991) 1.57
Estimating the relationship between disease progression and cost of care in dementia. Br J Psychiatry (2002) 1.55
Variation in the sequence and modification state of the human insulin gene flanking regions. Nucleic Acids Res (1982) 1.55
Blood glucose self-monitoring in type 2 diabetes: a randomised controlled trial. Health Technol Assess (2009) 1.54
Hypothermia-induced reversible platelet dysfunction. Ann Surg (1987) 1.51
Heparin causes platelet dysfunction and induces fibrinolysis before cardiopulmonary bypass. Ann Thorac Surg (1995) 1.51
Distinct phosphatidylinositol 3-kinase lipid products accumulate upon oxidative and osmotic stress and lead to different cellular responses. J Biol Chem (1999) 1.49
Deletion of glutamate receptor-A (GluR-A) AMPA receptor subunits impairs one-trial spatial memory. Behav Neurosci (2007) 1.48
Safety and therapeutic effectiveness of reinfused shed blood after open heart surgery. Ann Thorac Surg (1994) 1.45
Five-year results of a randomised controlled trial comparing mobile and fixed bearings in total knee replacement. Bone Joint J (2013) 1.43
Fluctuations in attention: PD dementia vs DLB with parkinsonism. Neurology (2002) 1.42
Estimating long-term cost savings from treatment of Alzheimer's disease. A modelling approach. Pharmacoeconomics (1999) 1.41
Suspected adverse reactions, 2000. Vet Rec (2001) 1.40
Antibodies to plasma proteins: an association with platelet transfusion refractoriness. Br J Haematol (1992) 1.40
Calcium-dependent unmasking of active center cysteine during activation of fibrin stabilizing factor. Biochemistry (1974) 1.40
Permethrin toxicity in cats. Vet Rec (2000) 1.40
Nucleotide sequence of a portion of human chromosome 9 containing a leukocyte interferon gene cluster. J Mol Biol (1982) 1.39
Suspected adverse reactions to valnemulin in pigs. Vet Rec (2000) 1.39
Reduction of bleeding after heart operations through the prophylactic use of epsilon-aminocaproic acid. J Thorac Cardiovasc Surg (1996) 1.39
Myopathy of internal anal sphincter with polyglucosan inclusions. J Pathol (1990) 1.39
Respiration of 13C-labeled substrates added to soil in the field and subsequent 16S rRNA gene analysis of 13C-labeled soil DNA. Appl Environ Microbiol (2003) 1.38
Platelet size as a determinant of platelet function. J Lab Clin Med (1983) 1.37
Candida lusitaniae: a new opportunistic pathogen of the urinary tract. Diagn Microbiol Infect Dis (1984) 1.34
A clinical and immunologic study of blood transfusion and postoperative bacterial infection in spinal surgery. Transfusion (1992) 1.34
Neutrophil and nonneutrophil-mediated injury in intestinal ischemia-reperfusion. Ann Surg (1993) 1.34
Restoration in vivo of erythrocyte adenosine triphosphate, 2,3-diphosphoglycerate, potassium ion, and sodium ion concentrations following the transfusion of acid-citrate-dextrose-stored human red blood cells. J Lab Clin Med (1969) 1.34
Association between transfusion of whole blood and recurrence of cancer. Br Med J (Clin Res Ed) (1986) 1.33
The impact of diabetes-related complications on healthcare costs: results from the United Kingdom Prospective Diabetes Study (UKPDS Study No. 65). Diabet Med (2003) 1.32
Attention and fluctuating attention in patients with dementia with Lewy bodies and Alzheimer disease. Arch Neurol (2001) 1.32
Follow-up of breast cancer in primary care vs specialist care: results of an economic evaluation. Br J Cancer (1999) 1.31
Arachidonic acid metabolism by platelets of differing size. Br J Haematol (1983) 1.29
Hematopoietic stem cell transplantation for multiply transfused patients with sickle cell disease and thalassemia after low-dose total body irradiation, fludarabine, and rabbit anti-thymocyte globulin. Bone Marrow Transplant (2005) 1.29
Decreased platelet inhibition by nitric oxide in two brothers with a history of arterial thrombosis. J Clin Invest (1996) 1.29
Platelet derived CD154 (CD40 ligand) and febrile responses to transfusion. Lancet (2001) 1.29
Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions. Biochem J (2001) 1.29
Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN. Oncogene (2009) 1.27
Infection or suspected infection after hip replacement surgery with autologous or homologous blood transfusions. Transfusion (1991) 1.26
The psychological impact of human papillomavirus testing in women with borderline or mildly dyskaryotic cervical smear test results: 6-month follow-up. Br J Cancer (2005) 1.26
Use of a high-sensitivity rapid strep test without culture confirmation of negative results: 2 years' experience. J Fam Pract (2000) 1.26
Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components. Biochem J (2000) 1.26
Cost-effectiveness analysis of intensive blood-glucose control with metformin in overweight patients with type II diabetes (UKPDS No. 51). Diabetologia (2001) 1.25
Cost-effectiveness of referral for generic care or problem-solving treatment from community mental health nurses, compared with usual general practitioner care for common mental disorders: Randomised controlled trial. Br J Psychiatry (2006) 1.23
Infrared fibers for radiometer thermometry in hypothermia and hyperthermia treatment. IEEE Trans Biomed Eng (1989) 1.22
Platelet size and age determine platelet function independently. Blood (1984) 1.22
Characterization of huJAM: evidence for involvement in cell-cell contact and tight junction regulation. Am J Physiol Cell Physiol (2000) 1.21
The relation between response to hypotonic stress and the 51Cr recovery in vivo of preserved platelets. Transfusion (1974) 1.21
Platelet size does not correlate with platelet age. Blood (1983) 1.19