Published in Blood on June 01, 1984
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Differential T cell costimulatory requirements in CD28-deficient mice. Science (1993) 6.93
The B7 and CD28 receptor families. Immunol Today (1994) 6.38
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Role of the CD28 receptor in T-cell activation. Immunol Today (1990) 4.89
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IL-7 enhances the survival and maintains the size of naive T cells. J Immunol (2001) 3.39
bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria. Development (1994) 3.34
Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death. Genes Dev (1998) 3.33
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Bcl-2-family proteins: the role of the BH3 domain in apoptosis. Trends Cell Biol (1998) 3.32
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Molecular basis of T cell inactivation by CTLA-4. Science (1998) 3.00
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Bcl-XL and Bcl-2 repress a common pathway of cell death. J Exp Med (1995) 2.94
CD28 is an inducible T cell surface antigen that transduces a proliferative signal in CD3+ mature thymocytes. J Immunol (1990) 2.84
Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane. J Biol Chem (2001) 2.76
Oral anticoagulants. Mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest (1992) 2.76
Sequence-specific binding of human Ets-1 to the T cell receptor alpha gene enhancer. Science (1990) 2.76
Regulation of surface and intracellular expression of CTLA4 on mouse T cells. J Immunol (1996) 2.69
Thymocyte expression of RAG-1 and RAG-2: termination by T cell receptor cross-linking. Science (1991) 2.65
The platelet function defect of cardiopulmonary bypass. Blood (1993) 2.63
Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion. J Exp Med (1993) 2.62
Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets. J Immunol (1993) 2.55
Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival. Proc Natl Acad Sci U S A (2000) 2.46
A case-control study of risk factors for sporadic hepatitis C virus infection in the southwestern United States. Am J Gastroenterol (1999) 2.37
Absence of B7-dependent responses in CD28-deficient mice. Immunity (1994) 2.32
Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage. Genes Dev (1996) 2.30
The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability. Cell Death Differ (2000) 2.29
Managing oral anticoagulant therapy. Chest (2001) 2.25
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Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis. Mol Cell Biol (2000) 2.24
CD28 ligation in T-cell activation: evidence for two signal transduction pathways. Blood (1990) 2.21
Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest (1998) 2.17
Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL. Mol Cell Biol (1997) 2.15
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Expression of bcl-xL can confer a multidrug resistance phenotype. Blood (1995) 2.11
CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes. Immunity (1996) 2.09
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Regulation of cell-type-specific interleukin-2 receptor alpha-chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-kappa B family proteins. Mol Cell Biol (1995) 2.07
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Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. Cell Death Differ (2003) 2.01
Bclx regulates the survival of double-positive thymocytes. Proc Natl Acad Sci U S A (1995) 2.00
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Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. J Am Coll Cardiol (1998) 1.95
Does erythrocyte infusion improve 3.2-km run performance at high altitude? Eur J Appl Physiol Occup Physiol (1998) 1.94
The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB. Mol Cell Biol (1993) 1.94
Apoptosis and disease: regulation and clinical relevance of programmed cell death. Annu Rev Med (1997) 1.91
In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proc Natl Acad Sci U S A (1996) 1.90
Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production. Oncogene (2011) 1.87
The central effectors of cell death in the immune system. Annu Rev Immunol (1999) 1.87
Electrical alternans and cardiac electrical instability. Circulation (1988) 1.86
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Identification of a novel regulatory domain in Bcl-X(L) and Bcl-2. EMBO J (1997) 1.83
CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival. Genes Dev (1997) 1.83
Overexpression of BCL-x protein in primary breast cancer is associated with high tumor grade and nodal metastases. Cancer J Sci Am (1997) 1.80
bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice. J Exp Med (1996) 1.79
CD28 is required for germinal center formation. J Immunol (1996) 1.78
Bcl-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation. Proc Natl Acad Sci U S A (1997) 1.78
Induction of nuclear factor kappaB by the CD30 receptor is mediated by TRAF1 and TRAF2. Mol Cell Biol (1997) 1.78
Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma protein. Science (1993) 1.77
Postischemic renal injury is mediated by neutrophils and leukotrienes. Am J Physiol (1989) 1.77
CD28 costimulation prevents cell death during primary T cell activation. J Immunol (1996) 1.76
Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2. Proc Natl Acad Sci U S A (1994) 1.76