Published in Oncogene on November 16, 2009
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Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cells. Mol Cell Biol (2011) 1.11
microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion. PLoS One (2012) 1.11
Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells. Biochem J (2014) 1.07
Upregulation of PTEN in glioma cells by cord blood mesenchymal stem cells inhibits migration via downregulation of the PI3K/Akt pathway. PLoS One (2010) 1.05
PTEN is a protein tyrosine phosphatase for IRS1. Nat Struct Mol Biol (2014) 1.05
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PTEN in liver diseases and cancer. World J Gastroenterol (2010) 0.97
A unified nomenclature and amino acid numbering for human PTEN. Sci Signal (2014) 0.95
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Targeting genomic alterations in squamous cell lung cancer. Front Oncol (2013) 0.85
Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes. J Med Genet (2014) 0.84
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Controlling PTEN (Phosphatase and Tensin Homolog) Stability: A DOMINANT ROLE FOR LYSINE 66. J Biol Chem (2016) 0.82
p53 regulation of podosome formation and cellular invasion in vascular smooth muscle cells. Cell Adh Migr (2011) 0.82
A genomic approach to study down syndrome and cancer inverse comorbidity: untangling the chromosome 21. Front Physiol (2015) 0.82
MicroRNA Expression Is Altered in an Ovalbumin-Induced Asthma Model and Targeting miR-155 with Antagomirs Reveals Cellular Specificity. PLoS One (2015) 0.80
Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1. Oncogene (2012) 0.80
p53 Down regulates PDGF-induced formation of circular dorsal ruffles in rat aortic smooth muscle cells. PLoS One (2014) 0.80
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Hypoxia-induced modulation of PTEN activity and EMT phenotypes in lung cancers. Cancer Cell Int (2016) 0.79
Involvement of TGFβ-induced phosphorylation of the PTEN C-terminus on TGFβ-induced acquisition of malignant phenotypes in lung cancer cells. PLoS One (2013) 0.79
The protein phosphatase activity of PTEN is essential for regulating neural stem cell differentiation. Mol Brain (2015) 0.79
Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities. Biochem Biophys Res Commun (2013) 0.78
Direct regulation of transforming growth factor β-induced epithelial-mesenchymal transition by the protein phosphatase activity of unphosphorylated PTEN in lung cancer cells. Cancer Sci (2015) 0.78
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PTEN redundancy: overexpressing lpten, a homolog of Dictyostelium discoideum ptenA, the ortholog of human PTEN, rescues all behavioral defects of the mutant ptenA-. PLoS One (2014) 0.76
Differential Requirement for Pten Lipid and Protein Phosphatase Activity during Zebrafish Embryonic Development. PLoS One (2016) 0.76
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Molecular mechanisms of peritoneal dissemination in gastric cancer. World J Gastroenterol (2016) 0.75
The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair. Sci Rep (2016) 0.75
PTEN Gene Induces Cell Invasion and Migration via Regulating AKT/GSK-3β/β-Catenin Signaling Pathway in Human Gastric Cancer. Dig Dis Sci (2017) 0.75
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The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells. Cancer Res (1998) 3.15
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Regulation of cell migration by the C2 domain of the tumor suppressor PTEN. Science (2004) 2.81
The role of PTEN signaling perturbations in cancer and in targeted therapy. Oncogene (2008) 2.66
Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis. J Biol Chem (2004) 2.60
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TGFbeta-induced downregulation of E-cadherin-based cell-cell adhesion depends on PI3-kinase and PTEN. J Cell Sci (2005) 1.63
The protein phosphatase activity of PTEN regulates SRC family kinases and controls glioma migration. Cancer Res (2008) 1.63
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TPIP: a novel phosphoinositide 3-phosphatase. Biochem J (2001) 1.60
Interfacial kinetic analysis of the tumour suppressor phosphatase, PTEN: evidence for activation by anionic phospholipids. Biochem J (2003) 1.59
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Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor. Proc Natl Acad Sci U S A (2005) 1.47
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A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells. EMBO J (2006) 1.34
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PTEN phosphatase selectively binds phosphoinositides and undergoes structural changes. Biochemistry (2008) 1.28
PTEN is destabilized by phosphorylation on Thr366. Biochem J (2007) 1.28
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Loss of PTEN selectively desensitizes upstream IGF1 and insulin signaling. Oncogene (2007) 0.92
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