Activation and inhibition of adenylate cyclase by hormones.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 7152075)

Published in Biochem Soc Trans on December 01, 1982

Authors

S Braun, A M Tolkovsky, M L Steer, H A Lester, A Levitzki

Articles by these authors

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity (1999) 7.78

Regulation of cellulose synthesis in Acetobacter xylinum by cyclic diguanylic acid. Nature (2008) 6.16

EGF induces tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signaling. Cell (1989) 5.68

puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila. Genes Dev (1998) 4.64

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor. Nature (1996) 4.04

From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor. Proc Natl Acad Sci U S A (1998) 3.99

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene (2001) 3.96

Autophagy is activated by apoptotic signalling in sympathetic neurons: an alternative mechanism of death execution. Mol Cell Neurosci (1999) 3.78

Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor. Mol Cell (1999) 3.73

A rat brain Na+ channel alpha subunit with novel gating properties. Neuron (1988) 3.48

Negative cooperativity in regulatory enzymes. Proc Natl Acad Sci U S A (1969) 3.38

The inward rectifier potassium channel family. Curr Opin Neurobiol (1995) 3.23

Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes. Neuron (1993) 3.10

Cloning and expression of a rat brain GABA transporter. Science (1990) 3.08

Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors. Nature (1995) 3.06

Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors. J Med Chem (1989) 3.02

Rates and equilibria at the acetylcholine receptor of Electrophorus electroplaques: a study of neurally evoked postsynaptic currents and of voltage-jump relaxations. J Gen Physiol (1977) 2.86

Transglutaminase is essential in receptor-mediated endocytosis of alpha 2-macroglobulin and polypeptide hormones. Nature (1980) 2.82

Genetic inactivation of an inwardly rectifying potassium channel (Kir4.1 subunit) in mice: phenotypic impact in retina. J Neurosci (2000) 2.72

Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds. Nat Neurosci (1999) 2.63

RGS proteins reconstitute the rapid gating kinetics of gbetagamma-activated inwardly rectifying K+ channels. Proc Natl Acad Sci U S A (1997) 2.43

Voltage clamping of Xenopus laevis oocytes utilizing agarose-cushion electrodes. Pflugers Arch (1994) 2.40

Pancreatic duct obstruction triggers acute necrotizing pancreatitis in the opossum. Gastroenterology (1993) 2.37

Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors. Science (1988) 2.35

A neutral amino acid change in segment IIS4 dramatically alters the gating properties of the voltage-dependent sodium channel. Proc Natl Acad Sci U S A (1990) 2.35

Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: early morphological changes during development of experimental pancreatitis. Am J Physiol (1984) 2.33

Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor. Science (1988) 2.31

Mitochondria are selectively eliminated from eukaryotic cells after blockade of caspases during apoptosis. Curr Biol (2001) 2.29

A-type potassium channels expressed from Shaker locus cDNA. Proc Natl Acad Sci U S A (1988) 2.26

Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function. Oncogene (2009) 2.23

Serine protease inhibitor causes F-actin redistribution and inhibition of calcium-mediated secretion in pancreatic acini. Gastroenterology (2001) 2.23

Kir4.1 potassium channel subunit is crucial for oligodendrocyte development and in vivo myelination. J Neurosci (2001) 2.23

Conductance increases produced by bath application of cholinergic agonists to Electrophorus electroplaques. J Gen Physiol (1975) 2.19

Metal-binding sites of concanavalin A and their role in the binding of alpha-methyl d-glucopyranoside. Biochem J (1968) 2.17

Numerical reconstruction of the quantal event at nicotinic synapses. Biophys J (1979) 2.17

Role of NAD(P)H oxidase in angiotensin II-induced JAK/STAT signaling and cytokine induction. Circ Res (2000) 2.16

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases. Proc Natl Acad Sci U S A (1998) 2.15

In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system. Methods Enzymol (1998) 2.15

Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells. J Natl Cancer Inst (1993) 2.14

Allosteric control of gating and kinetics at P2X(4) receptor channels. J Neurosci (1999) 2.10

Heteromeric olfactory cyclic nucleotide-gated channels: a subunit that confers increased sensitivity to cAMP. Proc Natl Acad Sci U S A (1994) 2.10

The interaction of concanavalin A with methyl alpha-D-glucopyranoside. Biochim Biophys Acta (1968) 2.09

Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers. Proc Natl Acad Sci U S A (1995) 2.09

Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress. Mol Cell Biol (2001) 2.08

Genetic variants of IL-13 signalling and human asthma and atopy. Hum Mol Genet (2000) 2.08

An open-channel blocker interacts with adjacent turns of alpha-helices in the nicotinic acetylcholine receptor. Neuron (1990) 2.06

Conducting states of a mammalian serotonin transporter. Neuron (1994) 1.96

Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors. Science (1994) 1.96

Novel pore-lining residues in CFTR that govern permeation and open-channel block. Neuron (1994) 1.96

Diversity of heterotrophic nitrogen fixation genes in a marine cyanobacterial mat. Appl Environ Microbiol (1995) 1.94

Acute necrotizing pancreatitis in the opossum: earliest morphological changes involve acinar cells. Gastroenterology (1992) 1.91

The 120 592 bp IncF plasmid pRSB107 isolated from a sewage-treatment plant encodes nine different antibiotic-resistance determinants, two iron-acquisition systems and other putative virulence-associated functions. Microbiology (2005) 1.91

Enhancement of neurotransmitter release induced by brain-derived neurotrophic factor in cultured hippocampal neurons. J Neurosci (1998) 1.91

Role of substance P and the neurokinin 1 receptor in acute pancreatitis and pancreatitis-associated lung injury. Proc Natl Acad Sci U S A (1998) 1.90

Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis. Am J Physiol (1995) 1.89

Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats. Am J Physiol (1998) 1.89

Mode of coupling between the beta-adrenergic receptor and adenylate cyclase in turkey erythrocytes. Biochemistry (1978) 1.87

Early ductal decompression prevents the progression of biliary pancreatitis: an experimental study in the opossum. Gastroenterology (1993) 1.87

Relaxation measurements on the acetylcholine receptor. Proc Natl Acad Sci U S A (1975) 1.86

The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions. EMBO J (1992) 1.85

Ion binding and permeation at the GABA transporter GAT1. J Neurosci (1996) 1.82

Messenger RNA coding for only the alpha subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes. Proc Natl Acad Sci U S A (1986) 1.79

Half-of-the-sites reactivity and the conformational states of cytidine triphosphate synthetase. Biochemistry (1971) 1.76

Secretagogue-induced digestive enzyme activation and cell injury in rat pancreatic acini. Am J Physiol (1999) 1.76

Voltage-dependent block of the cystic fibrosis transmembrane conductance regulator Cl- channel by two closely related arylaminobenzoates. J Gen Physiol (1993) 1.74

Rat brain expresses a heterogeneous family of calcium channels. Proc Natl Acad Sci U S A (1990) 1.73

Cisplatin induces PKB/Akt activation and p38(MAPK) phosphorylation of the EGF receptor. Oncogene (2006) 1.72

Tyrphostins inhibit epidermal growth factor (EGF)-receptor tyrosine kinase activity in living cells and EGF-stimulated cell proliferation. J Biol Chem (1989) 1.72

Synthetic tyrosine polymers as substrates and inhibitors of tyrosine-specific protein kinases. J Biol Chem (1984) 1.71

Effect of recombinant platelet-activating factor acetylhydrolase on two models of experimental acute pancreatitis. Gastroenterology (1998) 1.70

Epidermal-growth-factor-dependent activation of the src-family kinases. Eur J Biochem (1994) 1.68

Water immersion stress induces heat shock protein 60 expression and protects against pancreatitis in rats. Gastroenterology (2000) 1.68

Specific inhibition of insulin-like growth factor-1 and insulin receptor tyrosine kinase activity and biological function by tyrphostins. Endocrinology (1997) 1.68

The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injury. Gastroenterology (1999) 1.65

Cerulein-induced in vitro activation of trypsinogen in rat pancreatic acini is mediated by cathepsin B. Gastroenterology (1997) 1.64

Selective platelet-derived growth factor receptor kinase blockers reverse sis-transformation. Cancer Res (1994) 1.63

Subcellular redistribution of lysosomal enzymes during caerulein-induced pancreatitis. Am J Physiol (1987) 1.63

The role of negative cooperativity and half-of-the-sites reactivity in enzyme regulation. Curr Top Cell Regul (1976) 1.62

The cell biology of experimental pancreatitis. N Engl J Med (1987) 1.61

Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity. J Biol Chem (2000) 1.61

A covalently bound photoisomerizable agonist: comparison with reversibly bound agonists at Electrophorus electroplaques. J Gen Physiol (1980) 1.59

Postsynaptic action of cobra toxin at the myoneural junction. Nature (1970) 1.59

Activation of a potassium current by rapid photochemically generated step increases of intracellular calcium in rat sympathetic neurons. Proc Natl Acad Sci U S A (1987) 1.58

A multi-substrate single-file model for ion-coupled transporters. Biophys J (1996) 1.57

Flk-1 as a target for tumor growth inhibition. Cancer Res (1996) 1.56

Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells. Neuron (1996) 1.56

Pancreatitis. The role of lysosomes. Dig Dis Sci (1984) 1.56

Isolated and interactive impact of common CYP2C19 genetic variants on the antiplatelet effect of chronic clopidogrel therapy. J Thromb Haemost (2010) 1.52

Phosphatidylinositol 3-kinase-dependent activation of trypsinogen modulates the severity of acute pancreatitis. J Clin Invest (2001) 1.51

Dose-response relations for unnatural amino acids at the agonist binding site of the nicotinic acetylcholine receptor: tests with novel side chains and with several agonists. Mol Pharmacol (1996) 1.50

Signal therapy for RAS-induced cancers in combination of AG 879 and PP1, specific inhibitors for ErbB2 and Src family kinases, that block PAK activation. Cancer J (2001) 1.49

Multicenter analytical evaluation of a high-sensitivity troponin T assay. Clin Chim Acta (2011) 1.49

Expression and modulation of voltage-gated calcium channels after RNA injection in Xenopus oocytes. Science (1986) 1.46

Mouse-Torpedo hybrid acetylcholine receptors: functional homology does not equal sequence homology. Proc Natl Acad Sci U S A (1985) 1.46

Ligand specificity and characteristics of the beta-adrenergic receptor in turkey erythrocyte plasma membranes. J Mol Biol (1975) 1.43

An anti-Ras cancer potential of PP1, an inhibitor specific for Src family kinases: in vitro and in vivo studies. Cancer J (2001) 1.42

Incorporation of 1-deoxy-D-xylulose into isoprene and phytol by higher plants and algae. FEBS Lett (1997) 1.42

Adenylate cyclase activation by the beta-adrenergic receptors as a diffusion-controlled process. Biochemistry (1979) 1.42