Published in J Mol Biol on December 25, 1982
Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes. EMBO J (1985) 20.39
Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes. Protein Sci (1998) 2.52
Bound water molecules and conformational stabilization help mediate an antigen-antibody association. Proc Natl Acad Sci U S A (1994) 2.18
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X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor. EMBO J (1986) 1.76
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Identification of surface residues mediating tissue factor binding and catalytic function of the serine protease factor VIIa. Proc Natl Acad Sci U S A (1996) 1.44
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Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution. Science (1995) 12.94
Structure of 20S proteasome from yeast at 2.4 A resolution. Nature (1997) 12.73
X-ray structure analysis of a membrane protein complex. Electron density map at 3 A resolution and a model of the chromophores of the photosynthetic reaction center from Rhodopseudomonas viridis. J Mol Biol (1984) 8.85
The complete genome of the hyperthermophilic bacterium Aquifex aeolicus. Nature (1998) 7.77
A gated channel into the proteasome core particle. Nat Struct Biol (2000) 5.42
Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution. Nature (2012) 5.22
Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nat Genet (1996) 4.62
The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment. EMBO J (1989) 4.49
Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography. Opt Express (2006) 4.49
The structures of HsIU and the ATP-dependent protease HsIU-HsIV. Nature (2000) 4.46
Structure of bovine pancreatic trypsin inhibitor. Results of joint neutron and X-ray refinement of crystal form II. J Mol Biol (1984) 4.14
Proteasome from Thermoplasma acidophilum: a threonine protease. Science (1995) 3.62
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The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex. Nature (2000) 3.53
Crystallographic refinement and atomic models of two different forms of citrate synthase at 2.7 and 1.7 A resolution. J Mol Biol (1982) 3.28
Natural protein proteinase inhibitors and their interaction with proteinases. Eur J Biochem (1992) 3.27
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Crystallographic refinement and atomic models of the intact immunoglobulin molecule Kol and its antigen-binding fragment at 3.0 A and 1.0 A resolution. J Mol Biol (1980) 3.25
Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. II. Crystallographic refinement at 1.9 A resolution. J Mol Biol (1974) 3.17
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Crystallographic structure studies of an IgG molecule and an Fc fragment. Nature (1976) 3.00
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Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA. Nat Struct Biol (2000) 2.82
Crystal structure of a carbon monoxide dehydrogenase reveals a [Ni-4Fe-5S] cluster. Science (2001) 2.78
The structure of a complex of recombinant hirudin and human alpha-thrombin. Science (1990) 2.71
Structure and mechanism of the aberrant ba(3)-cytochrome c oxidase from thermus thermophilus. EMBO J (2000) 2.71
Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes. J Mol Biol (1993) 2.66
Human C1 inhibitor: primary structure, cDNA cloning, and chromosomal localization. Biochemistry (1986) 2.52
Amplified, frequency swept lasers for frequency domain reflectometry and OCT imaging: design and scaling principles. Opt Express (2005) 2.48
The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases. EMBO J (1988) 2.48
The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction. EMBO J (1990) 2.44
High-level biosynthetic substitution of methionine in proteins by its analogs 2-aminohexanoic acid, selenomethionine, telluromethionine and ethionine in Escherichia coli. Eur J Biochem (1995) 2.44
X-ray crystallographic structure of the light-harvesting biliprotein C-phycocyanin from the thermophilic cyanobacterium Mastigocladus laminosus and its resemblance to globin structures. J Mol Biol (1985) 2.42
Crystal structure of P22 tailspike protein: interdigitated subunits in a thermostable trimer. Science (1994) 2.41
The blue oxidases, ascorbate oxidase, laccase and ceruloplasmin. Modelling and structural relationships. Eur J Biochem (1990) 2.37
X-ray crystal structures of cytosolic glutathione S-transferases. Implications for protein architecture, substrate recognition and catalytic function. Eur J Biochem (1994) 2.37
The three-dimensional structure of class pi glutathione S-transferase in complex with glutathione sulfonate at 2.3 A resolution. EMBO J (1991) 2.36
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Crystal structure analysis of oxidized Pseudomonas aeruginosa azurin at pH 5.5 and pH 9.0. A pH-induced conformational transition involves a peptide bond flip. J Mol Biol (1991) 2.19
Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. Proc Natl Acad Sci U S A (1999) 2.19
Three-dimensional structure of the tetragonal crystal form of egg-white avidin in its functional complex with biotin at 2.7 A resolution. J Mol Biol (1993) 2.18
Refined crystal structure of ascorbate oxidase at 1.9 A resolution. J Mol Biol (1992) 2.18
Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1. Nature (1997) 2.17
Structural homology of reaction centers from Rhodopseudomonas sphaeroides and Rhodopseudomonas viridis as determined by x-ray diffraction. Proc Natl Acad Sci U S A (1986) 2.16
Structural basis for the activation of human procaspase-7. Proc Natl Acad Sci U S A (2001) 2.14
Pyrobaculum aerophilum sp. nov., a novel nitrate-reducing hyperthermophilic archaeum. Appl Environ Microbiol (1993) 2.13
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Structure of human des(1-45) factor Xa at 2.2 A resolution. J Mol Biol (1993) 2.07
Refined structure of the hirudin-thrombin complex. J Mol Biol (1991) 2.06
Refined three-dimensional structures of two cyanobacterial C-phycocyanins at 2.1 and 2.5 A resolution. A common principle of phycobilin-protein interaction. J Mol Biol (1987) 2.06
Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex. Nature (2000) 2.04
Crystal structure of a DNA-dependent RNA polymerase (DNA primase). Nat Struct Biol (2001) 2.03
Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases. Nature (1992) 2.02
The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity. EMBO J (1991) 1.99
Structural and functional aspects of domain motions in proteins. CRC Crit Rev Biochem (1984) 1.99
The molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-A resolution. Biochemistry (1975) 1.98
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Structure and bactericidal activity of an antibiotic dodecapeptide purified from bovine neutrophils. J Biol Chem (1988) 1.91
X-ray crystal structure of the blue oxidase ascorbate oxidase from zucchini. Analysis of the polypeptide fold and a model of the copper sites and ligands. J Mol Biol (1989) 1.90
CD81 extracellular domain 3D structure: insight into the tetraspanin superfamily structural motifs. EMBO J (2001) 1.90
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Mistletoe therapy in oncology. Cochrane Database Syst Rev (2008) 1.84
Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution. J Mol Biol (1985) 1.81
Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like fold. EMBO J (1999) 1.79
Crystal structure of bovine trypsinogen at 1-8 A resolution. II. Crystallographic refinement, refined crystal structure and comparison with bovine trypsin. J Mol Biol (1977) 1.79
Mutational studies on HslU and its docking mode with HslV. Proc Natl Acad Sci U S A (2000) 1.79
Comparison of two highly refined structures of bovine pancreatic trypsin inhibitor. J Mol Biol (1987) 1.77
Crystal and molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI. Eur J Biochem (1974) 1.76
X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor. EMBO J (1986) 1.76
Crystal structure of heat shock locus V (HslV) from Escherichia coli. Proc Natl Acad Sci U S A (1997) 1.75
Ultrahigh-speed optical coherence tomography imaging and visualization of the embryonic avian heart using a buffered Fourier Domain Mode Locked laser. Opt Express (2007) 1.75
The high-resolution X-ray crystal structure of the complex formed between subtilisin Carlsberg and eglin c, an elastase inhibitor from the leech Hirudo medicinalis. Structural analysis, subtilisin structure and interface geometry. Eur J Biochem (1987) 1.75
Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas. Science (1995) 1.74
Three-dimensional structure of class pi glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 A resolution. J Mol Biol (1992) 1.73
Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. Crystal structure determination and stereochemistry of the contact region. J Mol Biol (1973) 1.73
Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1. Proc Natl Acad Sci U S A (1998) 1.72
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The crystal structure of dihydrodipicolinate synthase from Escherichia coli at 2.5 A resolution. J Mol Biol (1995) 1.70
Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme. Proc Natl Acad Sci U S A (1998) 1.70
Renal vasoconstriction in cirrhosis evaluated by duplex Doppler ultrasonography. Hepatology (1993) 1.69
Crystal structure of D-amino acid oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2. Proc Natl Acad Sci U S A (1996) 1.68
The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity. EMBO J (1994) 1.68
Coherent structural dynamics and electronic correlations during an ultrafast insulator-to-metal phase transition in VO2. Phys Rev Lett (2007) 1.67
Crystal structure of phage P22 tailspike protein complexed with Salmonella sp. O-antigen receptors. Proc Natl Acad Sci U S A (1996) 1.66
The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium. Proc Natl Acad Sci U S A (2000) 1.65
A multicenter randomized controlled trial on the clinical impact of therapeutic drug monitoring in patients with newly diagnosed epilepsy. The Italian TDM Study Group in Epilepsy. Epilepsia (2000) 1.64
Structure-activity relationship in heparin: a synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity. Biochem Biophys Res Commun (1983) 1.62
The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study. Proc Natl Acad Sci U S A (1999) 1.62
Reaction mechanism of Escherichia coli dihydrodipicolinate synthase investigated by X-ray crystallography and NMR spectroscopy. Biochemistry (1997) 1.62
The 2.5 A X-ray crystal structure of the acid-stable proteinase inhibitor from human mucous secretions analysed in its complex with bovine alpha-chymotrypsin. EMBO J (1988) 1.61
Crystal structure and mechanism of CO dehydrogenase, a molybdo iron-sulfur flavoprotein containing S-selanylcysteine. Proc Natl Acad Sci U S A (1999) 1.60