F K Jansen

Author PubWeight™ 21.72‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Immunotoxins: hybrid molecules of monoclonal antibodies and a toxin subunit specifically kill tumour cells. Nature 1981 1.35
2 Kinetics of cytotoxicity induced by immunotoxins. Enhancement by lysosomotropic amines and carboxylic ionophores. J Biol Chem 1984 1.24
3 Study of the plasma clearance of antibody--ricin-A-chain immunotoxins. Evidence for specific recognition sites on the A chain that mediate rapid clearance of the immunotoxin. Eur J Biochem 1986 1.13
4 Immunotoxins: hybrid molecules combining high specificity and potent cytotoxicity. Immunol Rev 1982 1.11
5 Transplantation immunity: localization in mouse serum of antibodies responsible for haemagglutination, cytotoxicity and enhancement. Nature 1966 1.07
6 Endocytosis of an antibody ricin A-chain conjugate (immuno-A-toxin) adsorbed on colloidal gold. Effects of ammonium chloride and monensin. Exp Cell Res 1985 0.97
7 Human melanoma cells can be killed in vitro by an immunotoxin specific for melanoma-associated antigen p97. Int J Cancer 1982 0.93
8 Effects of therapy with T101 ricin A-chain immunotoxin in two leukemia patients. Blood 1986 0.93
9 HLA antigens and immunoresponsiveness to insulin in insulin-dependent diabetes mellitus. Tissue Antigens 1976 0.92
10 Virus induced diabetes and the immune system. I. Suggestion that appearance of diabetes depends on immune reactions. Diabetologia 1977 0.87
11 Determination of sensitivity of fresh leukemia cells to immunotoxins. Cancer Res 1986 0.87
12 Passive transfer of lymphocytes from diabetic man to athymic mouse. Lancet 1979 0.85
13 T-lymphocyte killing by T101-ricin A-chain immunotoxin: pH-dependent potentiation with lysosomotropic amines. Blood 1988 0.85
14 Optimal elimination of leukemic T cells from human bone marrow with T101-ricin A-chain immunotoxin. Blood 1985 0.83
15 Treatment of leukemia patients with T101 ricin A chain immunotoxins. Cancer Treat Res 1988 0.82
16 [Immunologic tolerance against insulin. A therapeutic goal to prevent immunological complications in the diabetic patient using insulin]. Med Welt 1972 0.82
17 A phase I study of T101-ricin A chain immunotoxin in refractory chronic lymphocytic leukemia. J Biol Response Mod 1988 0.81
18 Immune reactions to fractions of crystalline insulin. I. Significance of lymphocytic infiltrates in the endocrine and exocrine pancreas of mice. Diabetologia 1973 0.80
19 Cytotoxic effect of anti-Mr 67,000 protein immunotoxins on human tumors in a nude mouse model. Cancer Res 1985 0.80
20 Biochemical aspects of immunotoxin preparation. J Immunol Methods 1985 0.79
21 Immunotoxin enhancers. Cancer Treat Res 1988 0.78
22 Immune insulitis and manifest diabetes mellitus. Studies on the course of immune insulitis and the induction of diabetes mellitus in rabbits immunized with insulin. Virchows Arch A Pathol Anat Histol 1974 0.77
23 Virus induced diabetes and the immune system. II -- Evidence for an immune pathogenesis of the acute phase of diabetes. Biomedicine 1979 0.76
24 Evidence for absence of toxicity of T101 immunotoxin on human hematopoietic progenitor cells prior to bone marrow transplantation. Cancer Res 1985 0.76
25 [Proceedings; Correlation between insultitis, insulin antibodies and diabetes mellitus following immunization with insulin]. Verh Dtsch Ges Pathol 1974 0.75
26 Biochemical engineering of immunotoxins for ex vivo bone marrow transplantation and in vivo leukemia treatment. Targeted Diagn Ther 1989 0.75
27 [Proceedings: Immunologic demonstration of B and A cells in the pancreas of the DBA-mouse during EMC-virus infection]. Verh Dtsch Ges Pathol 1975 0.75
28 [Immunological side-effects of insulin preparations in animals (author's transl)]. Verh Dtsch Ges Pathol 1972 0.75
29 Potential for therapy of monoclonal antibodies coupled with toxins. Dev Biol Stand 1983 0.75
30 [Does the diabetes caused by viral infection in mice depend on immune reactions?]. C R Acad Sci Hebd Seances Acad Sci D 1977 0.75
31 Present potential of immunotoxins. Behring Inst Mitt 1984 0.75
32 [Autograft of bone marrow treated by immunotoxin T 101 for the treatment of T-cell leukemia and lymphoma. Initial clinical cases]. Presse Med 1985 0.75
33 [Artificial H-2 dependent carrier determinants of the insulin molecule]. Ann Immunol (Paris) 1977 0.75
34 Immune reactions to fractions of crystalline insulin. II. May peri-insulitis be produced by an antigen different from true Sanger insulin? Diabetologia 1973 0.75
35 HLA antigen associated immuneresponsiveness to insulin in insulin dependent diabetes mellitus [proceedings]. Z Immunitatsforsch Immunobiol 1976 0.75
36 [Differences in immunological reaction models--tolerance and immunity--between a monomeric insulin and an insulin containing insulin polymers]. Ann Inst Pasteur (Paris) 1972 0.75
37 Insulin labelled by coupling with peroxidase. Diabetologia 1973 0.75
38 [Value of T101 immunotoxin in bone marrow transplantation]. Pathol Biol (Paris) 1985 0.75
39 Biologically active A-chain of the plant toxin ricin expressed from a synthetic gene in Escherichia coli. Gene 1990 0.75
40 [Immunotoxins (author's transl)]. Nouv Presse Med 1982 0.75
41 Ricin A-chain cytotoxicity depends on its presentation to the cell membrane. Bioconjug Chem 1995 0.75
42 Immune reactions to fractions of crystallized insulin. 3. Relation between glucose tolerance, purification of insulin and insulin antibodies. Horm Metab Res 1973 0.75
43 Tolerance to high and low doses of natural crystalline insulin. Diabetologia 1971 0.75
44 [Immunotoxins]. Bull Cancer 1983 0.75
45 Studies on components of immunotoxins: purification of ricin and its subunits and influence of unreacted antibodies. Int J Cancer 1985 0.75
46 Toxin selection and modification: utilization of the A chain of ricin. Cancer Treat Res 1988 0.75