Published in Br J Pharmacol on March 01, 1981
Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr Clin Neurophysiol (1972) 16.34
THE USE OF ISOLATED ORGANS FOR DETECTING ACTIVE SUBSTANCES IN THE CIRCULATING BLOOD. Br J Pharmacol Chemother (1964) 9.77
The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation. J Anat (1962) 8.63
Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. J Neurochem (1966) 7.91
Antihypertensive effect of the oral angiotensin converting-enzyme inhibitor SQ 14225 in man. N Engl J Med (1978) 5.04
Preferential blockade of presynaptic alpha-adrenoceptors by yohimbine. Eur J Pharmacol (1975) 4.00
Immediate effects on human performance of a 1,5-genzodiazepine (clobazam) compared with the 1,4-benzodiazepines, chlordiazepoxide hydrochloride and diazepam. Br J Clin Pharmacol (1975) 3.89
A permanent change in brain function resulting from daily electrical stimulation. Exp Neurol (1969) 3.89
MEASUREMENT OF LOCAL BLOOD FLOW WITH HYDROGEN GAS. Circ Res (1964) 2.55
Histaminergic mechanisms in brain. Annu Rev Pharmacol Toxicol (1977) 2.38
Analytical study of microsomes and isolated subcellular membranes from rat liver. IV. Biochemical, physical, and morphological modifications of microsomal components induced by digitonin, EDTA, and pyrophosphate. J Cell Biol (1974) 2.36
Observations in man on a pulse-accelerating reflex from the voluntary muscles of the legs. J Physiol (1938) 2.34
Selective vasoconstriction in carotid vascular bed by methysergide: possible relevance to its antimigraine effect. Eur J Pharmacol (1974) 2.04
Pre- and postsynaptic effects of yohimbine stereoisomers on noradrenergic transmission in the pulmonary artery of the rabbit. Naunyn Schmiedebergs Arch Pharmacol (1979) 2.00
Active muscle vasodilatation produced by stimulation of the brain stem: its significance in the defence reaction. J Physiol (1960) 1.97
Evidence for two types of excitatory receptor for 5-hydroxytryptamine in dog isolated vasculature. Br J Pharmacol (1980) 1.86
Modulation of the evoked release of noradrenaline in canine saphenous vein via presynaptic receptors for adenosine but not ATP. Eur J Pharmacol (1979) 1.41
Spiperone: a ligand of choice for neuroleptic receptors. 1. Kinetics and characteristics of in vitro binding. Biochem Pharmacol (1978) 1.40
Problems associated with iontophoretic studies in the caudate nucleus and substantia nigra. Neuropharmacology (1974) 1.37
Carbon fibre microelectrodes. J Neurosci Methods (1979) 1.34
Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia. Science (1979) 1.33
Presynaptic receptor systems on the noradrenergic neurones of rat brain. Naunyn Schmiedebergs Arch Pharmacol (1977) 1.27
Possible subdivision of postsynaptic alpha-adrenoceptors mediating pressor responses in the pithed rat. Naunyn Schmiedebergs Arch Pharmacol (1979) 1.23
A quantitative study of the response to adenosine triphosphate of the blood vessels of the human hand and forearm. J Physiol (1954) 1.21
Focal contralateral myoclonus produced by inhibition of GABA action in the caudate nucleus of rats. Brain (1978) 1.16
Rat-brain pyruvate kinase: purification and effects of lithium. J Inorg Biochem (1979) 1.14
Ability of serotonin and norepinephrine to mimic the central effects of reserpine on vasomotor activity. Circ Res (1960) 1.12
Autonomic neuroeffector junctions--reflex vasodilatation of the skin. J Invest Dermatol (1977) 1.11
Substance P in the substantia nigra. Brain Res (1976) 1.10
Stimulation and inhibition of the sodium pump by cardioactive steroids in relation to their binding sites and their inotropic effect on guinea-pig isolated atria. Br J Pharmacol (1979) 1.08
Asymmetry of protein transport in two branches of bifurcating axons. Brain Res (1978) 1.04
Reduction in tyrosine hydroxylase activity in the rat amygdala induced by kindling stimulation. Brain Res (1978) 1.04
Receptors for 5-hydroxytryptamine on the sympathetic nerves of the rabbit heart. Naunyn Schmiedebergs Arch Pharmacol (1978) 1.04
Pharmacologic actions of capsaicin: apparent involvement of substance P and serotonin. Life Sci (1979) 1.02
Effect of dopamine receptor agonists and antagonists on release of dopamine in the rabbit caudate nucleus in vitro. Naunyn Schmiedebergs Arch Pharmacol (1978) 1.00
Enzymic studies on the biosynthesis of serotonin in mammalian brain. J Biol Chem (1970) 1.00
Evaluation of the discriminative effects of morphine in the rat. J Pharmacol Exp Ther (1976) 0.99
Electrophysiological basis for a rational approach to antidysrhythmic drug therapy. Adv Drug Res (1974) 0.99
Alternative mechanisms for the potentiation of the relaxation evoked by isoprenaline in aortae from young and aged rats. Eur J Pharmacol (1979) 0.98
Blockage by yohimbine of prazosin-resistant pressor effects of adrenaline in the pithed rat. Br J Pharmacol (1980) 0.97
Effects of nicotine administration and its withdrawal on plasma corticosterone and brain 5-hydroxyindoles. Psychopharmacology (Berl) (1979) 0.94
Inhibition by dopamine of 3H-noradrenaline release elicited by nerve stimulation in the isolated cat's nictitating membrane. Naunyn Schmiedebergs Arch Pharmacol (1975) 0.94
Monoamine oxidase in rat arteries: evidence for different forms and selective localization. Br J Pharmacol (1973) 0.91
Proceedings: Failure to induce experimental hypertension in rats after intraventricular injection of 6-hydroxydopamine. Br J Pharmacol (1972) 0.90
Naloxone-induced inhibition of ethanol dependence in mice. Nature (1977) 0.90
Specific in vivo binding of neuroleptic drugs in rat brain. Biochem Pharmacol (1977) 0.90
Potentiation and antagonism of serotonin effects on intracranial and extracranial vessels. Possible implications in migraine. Neurology (1978) 0.90
Cardiac electrophysiology of four neuroleptics: melperone, haloperidol, thioridazine and chlorpromazine. Naunyn Schmiedebergs Arch Pharmacol (1978) 0.88
Effects of procaine hydrochloride, diazepam, and diphenylhydantoin on seizure development in cortical and subcortical structures in rats. Electroencephalogr Clin Neurophysiol (1975) 0.88
The vascular effects of flunarizine as compared with those of other clinically used vasoactive substances. Arzneimittelforschung (1978) 0.88
Speed, accuracy, and strength of forelimb movement after unilateral pyramidotomy in rhesus monkeys. J Comp Physiol Psychol (1970) 0.87
Sufentanil, a very potent and extremely safe intravenous morphine-like compound in mice, rats and dogs. Arzneimittelforschung (1976) 0.86
Studies on renal dopamine receptors with a new agonist. Eur J Pharmacol (1978) 0.86
Adrenaline-induced cardiovascular changes after intrahypothalamic administration to rats. Eur J Pharmacol (1975) 0.86
Role of central and peripheral adrenergic mechanisms in neurogenic hypertension produced by brainstem lesions in rat. Circ Res (1974) 0.86
The pharmacology of seizures induced by sensitization with low intensity brain stimulation. Pharmacol Biochem Behav (1974) 0.86
Effects of viloxazine, its optical isomers and its major metabolites on biogenic amine uptake mechanisms in vitro and in vivo. Eur J Pharmacol (1978) 0.85
The role of metals in enzyme-catalyzed substitutions at each of the phosphorus atoms of ATP. Adv Enzymol Relat Areas Mol Biol (1979) 0.85
Dopamine and alpha adrenoceptor agonists inhibit neurotransmission in the cat spleen through different presynaptic receptors. J Pharmacol Exp Ther (1980) 0.85
Effects of (8beta)-8-[methylthio)methyl]-6-propylergoline on dopaminergic function and brain dopamine turnover in rats. Life Sci (1979) 0.84
Separation and quantification of metabolites of radiolabelled histamine in brain [proceedings]. Br J Pharmacol (1978) 0.84
Inhibition of 5-hydroxytryptamine reuptake by amitryptyline an zimelidine and its relationship to their therapeutic action. Psychopharmacology (Berl) (1979) 0.84
Effect of various antidepressant drugs on the spontaneous firing rate of locus coeruleus and dorsal raphe neurons of the rat. Eur J Pharmacol (1979) 0.83
Behavioral analysis of the effects of 15 anticonvulsants in the amygdaloid kindled rat. Psychopharmacology (Berl) (1979) 0.82
Changes in tactile discrimination and in visual reaching after successive and simultaneous bilateral posterior parietal ablations in the monkey. J Neurol Neurosurg Psychiatry (1962) 0.82
Serotonin synthesis with rat brain synaptosomes. Effects of serotonin and monoamineoxidase inhibitors. Biochem Pharmacol (1972) 0.81
Stimulation of the rabbit hypothalamus: caudal projections to respiratory and cardiovascular centres. J Physiol (1976) 0.81
Potentiation of a cardioinhibitory reflex by hypothalamic stimulation in the rabbit. Brain Res (1978) 0.81
Cardiovascular responses to intraventricular adrenaline in spontaneous hypertensive rats. Eur J Pharmacol (1978) 0.81
Applications of modern electroanalytical techniques to pharmaceutical chemistry. J Pharm Sci (1969) 0.80
Behavioural activation induced in the rat by substance P infusion into ventral tegmental area: implication of dopaminergic A10 neurones. Neurosci Lett (1979) 0.80
Increased utilization of dopamine in the nucleus accumbens but not in the cerebral cortex after dorsal raphe lesion in the rat. Neurosci Lett (1979) 0.80
Stages in development of high-pressure neurological syndrome in the mouse. J Appl Physiol Respir Environ Exerc Physiol (1979) 0.79
Determination of halothane-induced sleeping time in the rat: effect of prior administration of centrally active drugs. Br J Pharmacol (1976) 0.79
The effect of trauma on the formaldehyde-induced fluorescence of noradrenaline in the hypothalamus and brain stem of the rat. Brain Res (1975) 0.79
THE ESTIMATION OF BRADYKININOGEN CONTENT OF THE PLASMA. Acta Physiol Lat Am (1963) 0.79
Lithium-nucleotide interactions investigated by gel filtration. Anal Biochem (1975) 0.78
On the ability of narcotic antagonists to produce the narcotic cue. J Pharmacol Exp Ther (1976) 0.78
The effect of angiotensin converting enzyme inhibitor on baroreceptor reflexes in conscious dogs during sodium depletion [proceedings]. J Physiol (1979) 0.78
Comparison of the anti-hypertensive response to beta-adrenoceptor blocking drugs in intact and adrenal-demedullated spontaneously hypertensive rats. Br J Pharmacol (1980) 0.78
Identification with potassium and vanadate of two classes of specific ouabain binding sites in a (Na+ + K+) ATPase preparation from the guinea-pig heart. Biochem Pharmacol (1980) 0.78
Stimulation by dopamine of adenosine cyclic 3',5'-monophosphate formation in rat caudate nucleus: effect of lesions of the nigro-neostriatal pathway. Mol Pharmacol (1976) 0.77
The cardioactive properties of SC4453, a digoxin analogue with a C17 beta-pyridazine ring. Eur J Pharmacol (1979) 0.77
Inhibition of rabbit muscle pyruvate kinase by lithium [proceedings]. Br J Pharmacol (1977) 0.76
Change in sensitivity to halothane in the rat following administration of sodium barbitone in the drinking water [proceedings]. Br J Pharmacol (1976) 0.76
Receptor binding properties in vitro and in vivo of some long-acting opiates. Arch Int Pharmacodyn Ther (1978) 0.76
Focal penicillin epilepsy increases cyclic GMP in cerebral cortex. Brain Res (1978) 0.76
In vivo interaction of haloperidol and apomorphine. Arch Int Pharmacodyn Ther (1978) 0.76
Cardiovascular responses to centrally administered adrenaline in spontaneous hypertensive rats [proceedings]. Br J Pharmacol (1977) 0.76
Pharmacological prophylaxis in the kindling model of epilepsy. Arch Neurol (1977) 0.76
An opposing role for the adrenals in the hypotensive effects of propranolol in the spontaneously hypertensive rat. Eur J Pharmacol (1979) 0.75
Dopamine-mediated circling behaviour does not involve the nigro-tectal pathway. Exp Brain Res (1979) 0.75
Acute anticonvulsant effects of diphenylhydantoin, phenobarbital, and carbamazepine: a combined electroclinical and serum level study in amygdaloid kindled cats and baboons. Epilepsia (1976) 0.75
Activity, manipulation drive, and strength in monkeys subjected to low-level irradiation. J Comp Physiol Psychol (1955) 0.75
Performance of rhesus monkeys on selected laboratory tasks presented before and after a large single dose of whole-body x radiation. J Comp Physiol Psychol (1956) 0.75
An analysis of the cortical and striatal involvement in dyskinesia induced in rats by intracerebral injection of GABA-transaminase inhibitors and picrotoxin. Eur J Pharmacol (1980) 0.75
Dopamine mediated circling behaviour is modulated by lesions of the ventromedial nucleus of the thalamus [proceedings]. Br J Pharmacol (1979) 0.75