Published in J Biol Chem on August 25, 1981
Membrane receptors for bacterial toxins. Microbiol Rev (1983) 2.41
Rabbit intestinal glycoprotein receptor for Escherichia coli heat-labile enterotoxin lacking affinity for cholera toxin. Infect Immun (1982) 2.08
Rabbit sucrase-isomaltase contains a functional intestinal receptor for Clostridium difficile toxin A. J Clin Invest (1996) 1.26
Characterization of the receptor for cholera toxin and Escherichia coli heat-labile toxin in rabbit intestinal brush borders. Biochem J (1986) 1.17
Cholera toxin, LT-I, LT-IIa and LT-IIb: the critical role of ganglioside binding in immunomodulation by type I and type II heat-labile enterotoxins. Expert Rev Vaccines (2007) 1.17
Differential binding kinetics of cholera toxin to intestinal microvillus membrane during development. Infect Immun (1987) 1.09
Pathogenesis of Shigella diarrhea: rabbit intestinal cell microvillus membrane binding site for Shigella toxin. Infect Immun (1986) 1.06
Pathogenesis of Shigella diarrhea. XVI. Selective targetting of Shiga toxin to villus cells of rabbit jejunum explains the effect of the toxin on intestinal electrolyte transport. J Clin Invest (1989) 1.06
Characterization of the cholera toxin receptor on Balb/c 3T3 cells as a ganglioside similar to, or identical with, ganglioside GM1. No evidence for galactoproteins with receptor activity. Biochem J (1982) 1.04
Intestinal brush border membranes contain regulatory subunits of adenylyl cyclase. Proc Natl Acad Sci U S A (1987) 1.03
Characterization of tetanus toxin binding to rat brain membranes. Evidence for a high-affinity proteinase-sensitive receptor. Biochem J (1986) 0.95
Capping of cholera toxin-ganglioside GM1 complexes on mouse lymphocytes is accompanied by co-capping of alpha-actinin. J Cell Biol (1983) 0.93
AB toxins: a paradigm switch from deadly to desirable. Toxins (Basel) (2010) 0.88
Type II heat-labile enterotoxins: structure, function, and immunomodulatory properties. Vet Immunol Immunopathol (2012) 0.86
Fate of tetanus toxin bound to the surface of primary neurons in culture: evidence for rapid internalization. J Cell Biol (1985) 0.86
Intracellular potentiation between two second messenger systems may contribute to cholera toxin induced intestinal secretion in humans. Gut (2004) 0.83
Expression of DeltaF508 Cystic Fibrosis Transmembrane Regulator (CFTR) Decreases Membrane Sialylation. Open Respir Med J (2009) 0.77
Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains. J Cell Biol (1998) 4.94
A monoclonal antibody-defined antigen associated with gastrointestinal cancer is a ganglioside containing sialylated lacto-N-fucopentaose II. J Biol Chem (1982) 3.97
Identification of the gastrointestinal and pancreatic cancer-associated antigen detected by monoclonal antibody 19-9 in the sera of patients as a mucin. Cancer Res (1983) 3.15
Biosynthesis and function of gangliosides. Science (1976) 2.51
A carbohydrate domain common to both sialyl Le(a) and sialyl Le(X) is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1. J Biol Chem (1991) 2.40
Comparison of the carbohydrate-binding specificities of cholera toxin and Escherichia coli heat-labile enterotoxins LTh-I, LT-IIa, and LT-IIb. Infect Immun (1988) 2.32
Detection of gangliosides that bind cholera toxin: direct binding of 125I-labeled toxin to thin-layer chromatograms. Anal Biochem (1980) 2.29
Ganglioside inhibition of fibronectin-mediated cell adhesion to collagen. Proc Natl Acad Sci U S A (1979) 2.24
Functional incorporation of ganglioside into intact cells: induction of choleragen responsiveness. Proc Natl Acad Sci U S A (1976) 2.14
Crystal structure of the vinculin tail suggests a pathway for activation. Cell (1999) 2.03
A monosialoganglioside is a monoclonal antibody-defined antigen of colon carcinoma. Science (1981) 2.02
Disruption of the talin gene arrests mouse development at the gastrulation stage. Dev Dyn (2000) 1.98
Role of membrane gangliosides in the binding and action of bacterial toxins. J Membr Biol (1982) 1.97
Brefeldin A blocks the response of cultured cells to cholera toxin. Implications for intracellular trafficking in toxin action. J Biol Chem (1993) 1.95
The sequence of chick alpha-actinin reveals homologies to spectrin and calmodulin. J Biol Chem (1987) 1.95
Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site. J Cell Sci (1996) 1.95
alpha-Actinins and the DMD protein contain spectrin-like repeats. Cell (1988) 1.94
The focal-adhesion vasodilator-stimulated phosphoprotein (VASP) binds to the proline-rich domain in vinculin. Biochem J (1996) 1.89
Analysis of a human tumor-associated glycoprotein (TAG-72) identified by monoclonal antibody B72.3. Cancer Res (1986) 1.86
Disruption of the talin gene compromises focal adhesion assembly in undifferentiated but not differentiated embryonic stem cells. J Cell Biol (1998) 1.79
Characterisation of the paxillin-binding site and the C-terminal focal adhesion targeting sequence in vinculin. J Cell Sci (1994) 1.76
Requirement for Rho in integrin signalling. Cell Adhes Commun (1997) 1.66
The localization of laminin mRNA and protein in the postimplantation embryo and placenta of the mouse: an in situ hybridization and immunocytochemical study. Development (1988) 1.64
Utrophin actin binding domain: analysis of actin binding and cellular targeting. J Cell Sci (1995) 1.61
Identification of a talin binding site in the cytoskeletal protein vinculin. J Cell Biol (1989) 1.60
Primary sequence and domain structure of chicken vinculin. Biochem J (1989) 1.59
Analysis of the mammalian talin2 gene TLN2. Biochem Biophys Res Commun (2001) 1.57
Complete sequence of human vinculin and assignment of the gene to chromosome 10. Proc Natl Acad Sci U S A (1990) 1.57
ARF1 mediates paxillin recruitment to focal adhesions and potentiates Rho-stimulated stress fiber formation in intact and permeabilized Swiss 3T3 fibroblasts. J Cell Biol (1998) 1.55
Acidic phospholipids inhibit the intramolecular association between the N- and C-terminal regions of vinculin, exposing actin-binding and protein kinase C phosphorylation sites. Biochem J (1996) 1.50
Interaction of choleragen with the oligosaccharide of ganglioside GM1: evidence for multiple oligosaccharide binding sites. Biochemistry (1978) 1.50
Thyrotropin-ganglioside interactions and their relationship to the structure and function of thyrotropin receptors. Proc Natl Acad Sci U S A (1976) 1.48
Internalization and degradation of cholera toxin by cultured cells: relationship to toxin action. J Cell Biol (1982) 1.48
The RhoA-dependent assembly of focal adhesions in Swiss 3T3 cells is associated with increased tyrosine phosphorylation and the recruitment of both pp125FAK and protein kinase C-delta to focal adhesions. J Cell Sci (1994) 1.48
Cholera toxin and cell growth: role of membrane gangliosides. Proc Natl Acad Sci U S A (1974) 1.46
Analysis of the actin-binding domain of alpha-actinin by mutagenesis and demonstration that dystrophin contains a functionally homologous domain. J Cell Biol (1992) 1.43
A monoclonal antibody against meningococcus group B polysaccharides distinguishes embryonic from adult N-CAM. J Cell Biol (1986) 1.42
Detergent extraction of cholera toxin and gangliosides from cultured cells and isolated membranes. Biochim Biophys Acta (1982) 1.39
Structural analysis of homologous repeated domains in alpha-actinin and spectrin. Int J Biol Macromol (1989) 1.39
Anomalous behavior of CGP 12177A on beta 1-adrenergic receptors. J Recept Signal Transduct Res (1997) 1.38
Monoclonal antibodies directed against the human Leb blood group antigen. J Biol Chem (1981) 1.38
Mechanism of action of cholera toxin: studies on the lag period. J Membr Biol (1980) 1.36
Characterization of monoclonal antibodies B1 and B3 that react with mucinous adenocarcinomas. Cancer Res (1991) 1.34
Identification of the vinculin-binding site in the cytoskeletal protein alpha-actinin. Biochem J (1994) 1.32
Monoclonal IgM in a patient with paraproteinemic polyneuropathy binds to gangliosides containing disialosyl groups. Ann Neurol (1985) 1.32
Biosynthesis of glycolipids in virus-transformed cells. Biochim Biophys Acta (1974) 1.31
Absence of a specific ganglioside galactosyltransferase in mouse cells transformed by murine sarcoma virus. Proc Natl Acad Sci U S A (1974) 1.29
Cell surface proteins of NIL1 hamster fibroblasts labeled by a galactose oxidase, tritiated borohydride method. Cell (1974) 1.29
Gangliosides sensitize unresponsive fibroblasts to Escherichia coli heat-labile enterotoxin. J Clin Invest (1979) 1.27
Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling. Proc Natl Acad Sci U S A (2008) 1.25
Laminin binds specifically to sulfated glycolipids. Proc Natl Acad Sci U S A (1985) 1.25
Further characterisation of the talin-binding site in the cytoskeletal protein vinculin. J Cell Sci (1992) 1.23
Isolation and characterization of a vinculin cDNA from chick-embryo fibroblasts. Biochem J (1987) 1.23
My-1, the human myeloid-specific antigen detected by mouse monoclonal antibodies, is a sugar sequence found in lacto-N-fucopentaose III. Blood (1983) 1.23
The identification and characterisation of an actin-binding site in alpha-actinin by mutagenesis. FEBS Lett (1992) 1.22
Two distinct adhesion mechanisms in embryonic neural retina cells. I. A kinetic analysis. Dev Biol (1981) 1.21
Cholera toxin interactions with thyrotropin receptors on thyroid plasma membranes. Proc Natl Acad Sci U S A (1976) 1.20
Mechanism of action of cholera toxin: effect of receptor density and multivalent binding on activation of adenylate cyclase. J Membr Biol (1980) 1.20
The cholera toxin receptor ganglioside GM remains associated with triton X-100 cytoskeletons of BALB/c-3T3 cells. Exp Cell Res (1981) 1.20
Studies on mutarotases. II. Investigations of possible rate-limiting anomerizations in glucose metabolism. J Biol Chem (1968) 1.20
Synemin may function to directly link muscle cell intermediate filaments to both myofibrillar Z-lines and costameres. J Biol Chem (2001) 1.19
Ganglioside biosynthesis in mouse cells: glycosyltransferase activities in normal and virally-transformed lines. Biochem Biophys Res Commun (1972) 1.19
Mechanism of action of cholera toxin on intact cells. Generation of A1 peptide and activation of adenylate cyclase. J Biol Chem (1982) 1.18
Characterization of the receptor for cholera toxin and Escherichia coli heat-labile toxin in rabbit intestinal brush borders. Biochem J (1986) 1.17
Uptake and metabolism of gangliosides in transformed mouse fibroblasts. Relationship of ganglioside structure to choleragen response. J Biol Chem (1976) 1.17
Viral transformation of rat myoblasts: effects on fusion and surface properties. Dev Biol (1976) 1.17
A sensitive enzymatic assay for determination of cholesterol in lipid extracts. Anal Biochem (1984) 1.16
Escherichia coli heat-labile enterotoxin. Ganglioside specificity and ADP-ribosyltransferase activity. J Biol Chem (1981) 1.16
Detection of glycolipid ligands by direct binding of carbohydrate-binding proteins to thin-layer chromatograms. Methods Enzymol (1982) 1.15
Distribution of fibronectin in the ectoderm of gastrulating chick embryos. Nature (1979) 1.14
Quantifying cell-matrix adhesion dynamics in living cells using interference reflection microscopy. J Microsc (2008) 1.14
Effect of gangliosides and substrate analogues on the hydrolysis of nicotinamide adenine dinucleotide by choleragen. Proc Natl Acad Sci U S A (1977) 1.11
The use of Rous sarcoma virus transformation mutants with differing tyrosine kinase activities to study the relationships between vinculin phosphorylation, pp60v-src location and adhesion plaque integrity. Exp Cell Res (1986) 1.11
Tetanus toxin binding to mouse spinal cord cells: an evaluation of the role of gangliosides in toxin internalization. Brain Res (1988) 1.11
Covalent crosslinking of human chorionic gonadotropin to its receptor in rat testes. Proc Natl Acad Sci U S A (1981) 1.10
Talin contains three similar vinculin-binding sites predicted to form an amphipathic helix. Biochem J (1999) 1.10
Biosynthesis and localization of gangliosides in cultured cells. Biochemistry (1982) 1.09
Many monoclonal antibodies with an apparent specificity for certain lung cancers are directed against a sugar sequence found in lacto-N-fucopentaose III. Arch Biochem Biophys (1983) 1.09
Tumour basement membrane laminin in adenocarcinoma of rectum: an immunohistochemical study of biological and clinical significance. Int J Cancer (1986) 1.09
Induction of glycolipid biosynthesis by sodium butyrate in HeLa cells. Biochem Biophys Res Commun (1974) 1.09
Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity. Exp Cell Res (1996) 1.08
Gangliosides as bimodal regulators of cell growth. Proc Natl Acad Sci U S A (1987) 1.07
The cDNA sequence of a human placental alpha-actinin. Nucleic Acids Res (1989) 1.06
Expression of chicken vinculin complements the adhesion-defective phenotype of a mutant mouse F9 embryonal carcinoma cell. J Cell Biol (1993) 1.06
Incorporation of fluorescent gangliosides into human fibroblasts: mobility, fate, and interaction with fibronectin. J Cell Biol (1984) 1.06
Organization of the human gene encoding the cytoskeletal protein vinculin and the sequence of the vinculin promoter. J Biol Chem (1993) 1.05
Exogenous gangliosides enhance the interaction of fibronectin with ganglioside-deficient cells. Exp Cell Res (1983) 1.05
Laminin and fibronectin in rectal adenocarcinoma: relationship to tumour grade, stage and metastasis. Br J Cancer (1984) 1.05
Different mechanisms of desensitization of adenylate cyclase by isoproterenol and prostaglandin E1 in human fibroblasts. Role of regulatory components in desensitization. J Biol Chem (1982) 1.05
Gangliosides as receptors for fibronectin? Comparison of cell spreading on a ganglioside-specific ligand with that on fibronectin. Exp Cell Res (1982) 1.05
Mutually exclusive splicing of calcium-binding domain exons in chick alpha-actinin. J Biol Chem (1992) 1.04
Direct visualization of redistribution and capping of fluorescent gangliosides on lymphocytes. J Cell Biol (1984) 1.04
Morphological changes in cultured mammalian cells: prevention by the calcium ionophore A23187. Cell (1975) 1.04
Isolation and characterization of a cDNA encoding a chick alpha-actinin. J Biol Chem (1987) 1.04
Uptake and metabolism of exogenous gangliosides by cultured cells: effect of choleragen on the turnover of GM1. J Lipid Res (1983) 1.04
Morphological alterations and ganglioside sialyltransferase activity induced by small fatty acids in HeLa cells. J Cell Biol (1975) 1.04
Characterization of the cholera toxin receptor on Balb/c 3T3 cells as a ganglioside similar to, or identical with, ganglioside GM1. No evidence for galactoproteins with receptor activity. Biochem J (1982) 1.04
Biosynthesis of bovine thyroid gangliosides. J Biol Chem (1978) 1.04
Monoclonal antibodies recognizing the N- and C-terminal regions of talin disrupt actin stress fibers when microinjected into human fibroblasts. Cell Motil Cytoskeleton (1997) 1.04