Published in Psychopharmacol Bull on January 01, 1980
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The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein. Nat Genet (1997) 5.39
Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A. Science (1993) 5.05
Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer. Br J Cancer (2009) 2.76
Low urinary cortisol excretion in Holocaust survivors with posttraumatic stress disorder. Am J Psychiatry (1995) 2.39
A mutation in the Norrie disease gene (NDP) associated with X-linked familial exudative vitreoretinopathy. Nat Genet (1993) 2.23
Herpes simplex virus type 1 DNA amplified as bacterial artificial chromosome in Escherichia coli: rescue of replication-competent virus progeny and packaging of amplicon vectors. Hum Gene Ther (1998) 2.13
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A defective HSV-1 vector expresses Escherichia coli beta-galactosidase in cultured peripheral neurons. Science (1988) 2.02
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Mutant torsinA, responsible for early-onset torsion dystonia, forms membrane inclusions in cultured neural cells. Hum Mol Genet (2000) 1.90
Self-contained, tetracycline-regulated retroviral vector system for gene delivery to mammalian cells. J Virol (1996) 1.82
Retrograde axonal transport of herpes simplex virus: evidence for a single mechanism and a role for tegument. Proc Natl Acad Sci U S A (2000) 1.81
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Structural features of human monoamine oxidase A elucidated from cDNA and peptide sequences. J Neurochem (1988) 1.77
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Temperature-sensitive divisionless mutant of Bacillus subtilis defective in the initiation of septation. J Bacteriol (1973) 1.66
Low urinary cortisol excretion in patients with posttraumatic stress disorder. J Nerv Ment Dis (1990) 1.63
Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies. J Natl Cancer Inst (1998) 1.60
Human monoamine oxidase A gene determines levels of enzyme activity. Am J Hum Genet (1991) 1.56
Dose-response changes in plasma cortisol and lymphocyte glucocorticoid receptors following dexamethasone administration in combat veterans with and without posttraumatic stress disorder. Arch Gen Psychiatry (1995) 1.53
Immunocytochemical demonstration of monoamine oxidase B in brain astrocytes and serotonergic neurons. Proc Natl Acad Sci U S A (1982) 1.53
Hypothalamic-pituitary-adrenal dysfunction in posttraumatic stress disorder. Biol Psychiatry (1991) 1.52
Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome. Mol Ther (2001) 1.45
Neural precursor cells for delivery of replication-conditional HSV-1 vectors to intracerebral gliomas. Mol Ther (2000) 1.45
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Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: implications for noninvasive imaging of transgene expression. Neoplasia (1999) 1.44
Single-step conversion of cells to retrovirus vector producers with herpes simplex virus-Epstein-Barr virus hybrid amplicons. J Virol (1999) 1.43
Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression. Science (1988) 1.42
Dissociation in aging Holocaust survivors. Am J Psychiatry (1996) 1.42
Parkin deletions in a family with adult-onset, tremor-dominant parkinsonism: expanding the phenotype. Ann Neurol (2000) 1.40
Localization of the gene for familial dysautonomia on chromosome 9 and definition of DNA markers for genetic diagnosis. Nat Genet (1993) 1.36
Urinary free-cortisol levels in posttraumatic stress disorder patients. J Nerv Ment Dis (1986) 1.35
Structural gene for beta-nerve growth factor not defective in familial dysautonomia. Proc Natl Acad Sci U S A (1984) 1.32
Biochemistry and genetics of monoamine oxidase. Pharmacol Ther (1990) 1.29
Molecular imaging of gene therapy for cancer. Gene Ther (2004) 1.28
Isolation and characterization of a candidate gene for Norrie disease. Nat Genet (1992) 1.27
Rapid-onset dystonia-parkinsonism. Neurology (1993) 1.26
Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy. Hum Gene Ther (1997) 1.26
Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene. New Biol (1991) 1.22
Comparative efficacy of expression of genes delivered to mouse sensory neurons with herpes virus vectors. J Comp Neurol (1994) 1.21
Clinical findings of a myoclonus-dystonia family with two distinct mutations. Neurology (2002) 1.20
Dinucleotide repeat polymorphism (D16S285) on human chromosome 16. Nucleic Acids Res (1991) 1.20
Dystonia in Ashkenazi Jews: clinical characterization of a founder mutation. Ann Neurol (1994) 1.19
Choline acetyltransferase activity is increased in combined cultures of spinal cord and muscle cells from mice. Science (1973) 1.19
Novel mutation in the TOR1A (DYT1) gene in atypical early onset dystonia and polymorphisms in dystonia and early onset parkinsonism. Neurogenetics (2001) 1.18
Glucocorticoid receptor number and cortisol excretion in mood, anxiety, and psychotic disorders. Biol Psychiatry (1993) 1.18
Impact of cumulative lifetime trauma and recent stress on current posttraumatic stress disorder symptoms in holocaust survivors. Am J Psychiatry (1995) 1.18
Lymphocyte glucocorticoid receptor number in posttraumatic stress disorder. Am J Psychiatry (1991) 1.17
Voltage-sensitive calcium channels regulate guanosine 3',5'-cyclic monophosphate levels in neuroblastoma cells. Proc Natl Acad Sci U S A (1978) 1.17
The role of marital interaction in chronic pain and depressive symptom severity. J Psychosom Res (1990) 1.17
Perinuclear biogenesis of mutant torsin-A inclusions in cultured cells infected with tetracycline-regulated herpes simplex virus type 1 amplicon vectors. Neuroscience (2004) 1.16
Expression of the early-onset torsion dystonia gene (DYT1) in human brain. Ann Neurol (1998) 1.16
Choline acetyltransferase activity of spinal cord cell cultures increased by co-culture with muscle and by muscle-conditioned medium. J Cell Biol (1977) 1.16
Long-term survival of rats harboring brain neoplasms treated with ganciclovir and a herpes simplex virus vector that retains an intact thymidine kinase gene. Cancer Res (1994) 1.15
Mutations in DYT1: extension of the phenotypic and mutational spectrum. Neurology (2004) 1.15
Prodrug activation enzymes in cancer gene therapy. J Gene Med (2000) 1.14
Green fluorescent protein as a reporter for retrovirus and helper virus-free HSV-1 amplicon vector-mediated gene transfer into neural cells in culture and in vivo. Neuroreport (1997) 1.13
The Pain Behavior Check List (PBCL): factor structure and psychometric properties. J Behav Med (1991) 1.13
Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants. New Biol (1990) 1.13
Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo. Cancer Res (2001) 1.12
Distribution of the mRNAs encoding torsinA and torsinB in the normal adult human brain. Ann Neurol (1999) 1.12
Dopamine transmission in DYT1 dystonia: a biochemical and autoradiographical study. Neurology (2002) 1.12
Gene delivery to glioma cells in rat brain by grafting of a retrovirus packaging cell line. J Neurosci Res (1990) 1.10
Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat. Proc Natl Acad Sci U S A (1994) 1.09
Linkage disequilibrium between the juvenile neuronal ceroid lipofuscinosis gene and marker loci on chromosome 16p 12.1. Am J Hum Genet (1994) 1.08
HSV/AAV hybrid amplicon vectors extend transgene expression in human glioma cells. Hum Gene Ther (1997) 1.08
Delivery of herpesvirus and adenovirus to nude rat intracerebral tumors after osmotic blood-brain barrier disruption. Proc Natl Acad Sci U S A (1995) 1.08
Gene therapy of malignant brain tumors: a rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells. J Neurosci Res (1992) 1.08
Selection for neuroblastoma cells that synthesize certain transmitters. Proc Natl Acad Sci U S A (1974) 1.07
Altered nerve growth factor in fibroblasts from patients with familial dysautonomia. Proc Natl Acad Sci U S A (1980) 1.05
Specificity of antisera prepared against pure bovine MAO-B. Brain Res (1983) 1.05
The TOR1A (DYT1) gene family and its role in early onset torsion dystonia. Genomics (1999) 1.05
DNA polymorphisms for the nerve growth factor receptor gene exclude its role in familial dysautonomia. Mol Biol Med (1986) 1.04
Pre-existing herpes simplex virus 1 (HSV-1) immunity decreases, but does not abolish, gene transfer to experimental brain tumors by a HSV-1 vector. Gene Ther (1998) 1.04
Personality disorders in treatment-seeking combat veterans with posttraumatic stress disorder. Am J Psychiatry (1993) 1.04
Exclusion of chromosome regions 6p12 and 15q11, but not chromosome region 7p11, in a German family with autosomal dominant congenital nystagmus. Genomics (1998) 1.04
Gene therapy in the CNS. Gene Ther (2000) 1.04
Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors. Hum Gene Ther (1994) 1.03
Grafting genetically modified cells into the rat brain: characteristics of E. coli beta-galactosidase as a reporter gene. Brain Res Mol Brain Res (1989) 1.03
Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain. Am J Pathol (1995) 1.03
Antitumor activity and reporter gene transfer into rat brain neoplasms inoculated with herpes simplex virus vectors defective in thymidine kinase or ribonucleotide reductase. Gene Ther (1994) 1.02
Gene transfer into the mammalian inner ear using HSV-1 and vaccinia virus vectors. Hear Res (1999) 1.02
Herpes vector-mediated delivery of marker genes to disseminated central nervous system tumors. Hum Gene Ther (1996) 1.02
Tumor cell endocytosis imaging facilitates delineation of the glioma-brain interface. Exp Neurol (1997) 1.01
Transgene inheritance and retroviral infection contribute to the efficiency of gene expression in solid tumors inoculated with retroviral vector producer cells. Gene Ther (1995) 1.01
Gene transfer into hepatocytes mediated by helper virus-free HSV/AAV hybrid vectors. Mol Med (1997) 1.00
A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study. Am J Pathol (2001) 1.00
Gene therapy for brain tumors. Brain Pathol (1995) 1.00
Multimodal cancer treatment mediated by a replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus thymidine kinase gene therapies. Cancer Res (1999) 1.00
Presence of free cyclic AMP receptor protein and regulation of its level by cyclic AMP in neuroblastoma-glioma hybrid cells. Proc Natl Acad Sci U S A (1979) 0.99
Urinary catecholamine excretion and severity of PTSD symptoms in Vietnam combat veterans. J Nerv Ment Dis (1992) 0.99
Treatment of implantable NF2 schwannoma tumor models with oncolytic herpes simplex virus G47Delta. Cancer Gene Ther (2007) 0.99
Gene for monoamine oxidase type A assigned to the human X chromosome. J Neurosci (1981) 0.98
Highly polymorphic (GT)n repeat sequence in intron II of the human MAOB gene. Genomics (1992) 0.98
Experimental tumor therapy in mice using the cyclophosphamide-activating cytochrome P450 2B1 gene. Hum Gene Ther (1994) 0.98
Benefits and risks of hosting animal cells in the human brain. Nat Med (1997) 0.98
New prodrug activation gene therapy for cancer using cytochrome P450 4B1 and 2-aminoanthracene/4-ipomeanol. Hum Gene Ther (1998) 0.97