Published in Cell on March 01, 1980
tRNA biology charges to the front. Genes Dev (2010) 4.07
Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1. EMBO J (1998) 3.87
An early step in wobble uridine tRNA modification requires the Elongator complex. RNA (2005) 3.01
Nuclear pore proteins are involved in the biogenesis of functional tRNA. EMBO J (1996) 2.90
Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA. Mol Cell Biol (1998) 2.83
The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus. J Cell Biol (1990) 2.82
Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins. Genes Dev (1999) 2.56
Nucleocytoplasmic transport of macromolecules. Microbiol Mol Biol Rev (1997) 2.51
tRNA nuclear export in saccharomyces cerevisiae: in situ hybridization analysis. Mol Biol Cell (1998) 2.40
The role of exportin-t in selective nuclear export of mature tRNAs. EMBO J (1998) 2.40
Transport into and out of the cell nucleus. EMBO J (1998) 2.38
Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121. Genes Dev (1998) 2.30
Nuclear tRNA aminoacylation and its role in nuclear export of endogenous tRNAs in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1999) 2.05
Cloning and characterization of LOS1, a Saccharomyces cerevisiae gene that affects tRNA splicing. Mol Cell Biol (1987) 2.00
Effects of alterations in the 3' flanking sequence on in vivo and in vitro expression of the yeast SUP4-o tRNATyr gene. EMBO J (1985) 1.87
Retrograde movement of tRNAs from the cytoplasm to the nucleus in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2005) 1.82
In vivo pre-tRNA processing in Saccharomyces cerevisiae. Mol Cell Biol (1991) 1.81
Possibility of cytoplasmic pre-tRNA splicing: the yeast tRNA splicing endonuclease mainly localizes on the mitochondria. Mol Biol Cell (2003) 1.80
Coordination of tRNA nuclear export with processing of tRNA. RNA (1999) 1.74
SEN1, a positive effector of tRNA-splicing endonuclease in Saccharomyces cerevisiae. Mol Cell Biol (1992) 1.71
Isolation and characterization of MOD5, a gene required for isopentenylation of cytoplasmic and mitochondrial tRNAs of Saccharomyces cerevisiae. Mol Cell Biol (1987) 1.67
RRP1, a Saccharomyces cerevisiae gene affecting rRNA processing and production of mature ribosomal subunits. J Bacteriol (1987) 1.65
Importin 7 and importin alpha/importin beta are nuclear import receptors for the glucocorticoid receptor. Mol Biol Cell (2004) 1.59
Nuclear RNA export pathways. Mol Cell Biol (2000) 1.58
Adjacent pol II and pol III promoters: transcription of the yeast retrotransposon Ty3 and a target tRNA gene. Nucleic Acids Res (1991) 1.46
MOD5 translation initiation sites determine N6-isopentenyladenosine modification of mitochondrial and cytoplasmic tRNA. Mol Cell Biol (1991) 1.44
Yeast nucleoporin mutants are defective in pre-tRNA splicing. Mol Cell Biol (1996) 1.43
Role of nuclear pools of aminoacyl-tRNA synthetases in tRNA nuclear export. Mol Biol Cell (2001) 1.43
The 3' end CCA of mature tRNA is an antideterminant for eukaryotic 3'-tRNase. RNA (1999) 1.39
TPD1 of Saccharomyces cerevisiae encodes a protein phosphatase 2C-like activity implicated in tRNA splicing and cell separation. Mol Cell Biol (1994) 1.37
Rapid and reversible nuclear accumulation of cytoplasmic tRNA in response to nutrient availability. Mol Biol Cell (2007) 1.35
A Los1p-independent pathway for nuclear export of intronless tRNAs in Saccharomycescerevisiae. Proc Natl Acad Sci U S A (2002) 1.34
Cse1p is involved in export of yeast importin alpha from the nucleus. Mol Cell Biol (1998) 1.33
Defects in tRNA processing and nuclear export induce GCN4 translation independently of phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. Mol Cell Biol (2000) 1.29
Regulation of tRNA bidirectional nuclear-cytoplasmic trafficking in Saccharomyces cerevisiae. Mol Biol Cell (2009) 1.28
Altered maturation of sequences at the 3' terminus of 5S gene transcripts in a Saccharomyces cerevisiae mutant that lacks a RNA processing endonuclease. EMBO J (1983) 1.26
Isolation of a yeast gene involved in species-specific pre-tRNA processing. Mol Cell Biol (1988) 1.25
PTA1, an essential gene of Saccharomyces cerevisiae affecting pre-tRNA processing. Mol Cell Biol (1992) 1.24
Transfer RNA post-transcriptional processing, turnover, and subcellular dynamics in the yeast Saccharomyces cerevisiae. Genetics (2013) 1.20
tRNA synthesis: identification of in vivo precursor tRNAs from parental and mutant yeast strains. Nucleic Acids Res (1981) 1.19
Presence of albumin mRNA precursors in nuclei of analbuminemic rat liver lacking cytoplasmic albumin mRNA. Proc Natl Acad Sci U S A (1982) 1.17
Assembly of a tRNA splicing complex: evidence for concerted excision and joining steps in splicing in vitro. Mol Cell Biol (1986) 1.17
Inorganic phosphate deprivation causes tRNA nuclear accumulation via retrograde transport in Saccharomyces cerevisiae. Genetics (2007) 1.12
PAUSED encodes the Arabidopsis exportin-t ortholog. Plant Physiol (2003) 1.10
Accumulation of pre-tRNA splicing '2/3' intermediates in a Saccharomyces cerevisiae mutant. EMBO J (1990) 1.09
Calcineurin-dependent nuclear import of the transcription factor Crz1p requires Nmd5p. J Cell Biol (2001) 1.09
Competition between a sterol biosynthetic enzyme and tRNA modification in addition to changes in the protein synthesis machinery causes altered nonsense suppression. Proc Natl Acad Sci U S A (2000) 1.05
Division of labor among the yeast Sol proteins implicated in tRNA nuclear export and carbohydrate metabolism. Genetics (2004) 1.04
Sites of RNA polymerase III transcription initiation and Ty3 integration at the U6 gene are positioned by the TATA box. Proc Natl Acad Sci U S A (1993) 1.03
STP1, a gene involved in pre-tRNA processing, encodes a nuclear protein containing zinc finger motifs. Mol Cell Biol (1992) 1.02
Los1p, involved in yeast pre-tRNA splicing, positively regulates members of the SOL gene family. Genetics (1996) 0.92
Rsp5 ubiquitin ligase modulates translation accuracy in yeast Saccharomyces cerevisiae. RNA (2005) 0.90
Have tRNA, will travel. Proc Natl Acad Sci U S A (2005) 0.89
Coordination of tRNA transcription with export at nuclear pore complexes in budding yeast. Genes Dev (2014) 0.88
Genome-wide investigation of the role of the tRNA nuclear-cytoplasmic trafficking pathway in regulation of the yeast Saccharomyces cerevisiae transcriptome and proteome. Mol Cell Biol (2013) 0.86
Altered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1p. Mol Biol Cell (2011) 0.86
P-body components, Dhh1 and Pat1, are involved in tRNA nuclear-cytoplasmic dynamics. RNA (2011) 0.84
Beyond tRNA cleavage: novel essential function for yeast tRNA splicing endonuclease unrelated to tRNA processing. Genes Dev (2012) 0.82
In vivo biochemical analyses reveal distinct roles of β-importins and eEF1A in tRNA subcellular traffic. Genes Dev (2015) 0.82
A rapid and sensitive non-radioactive method applicable for genome-wide analysis of Saccharomyces cerevisiae genes involved in small RNA biology. Yeast (2013) 0.82
RNA Export through the NPC in Eukaryotes. Genes (Basel) (2015) 0.82
Control of Saccharomyces cerevisiae pre-tRNA processing by environmental conditions. RNA (2016) 0.82
Separate responses of karyopherins to glucose and amino acid availability regulate nucleocytoplasmic transport. Mol Biol Cell (2014) 0.81
A methods review on use of nonsense suppression to study 3' end formation and other aspects of tRNA biogenesis. Gene (2014) 0.80
Genome-wide screen uncovers novel pathways for tRNA processing and nuclear-cytoplasmic dynamics. Genes Dev (2015) 0.77
Characterization of karyopherins in androgen receptor intracellular trafficking in the yeast model. Int J Clin Exp Pathol (2014) 0.77
Multiple Layers of Stress-Induced Regulation in tRNA Biology. Life (Basel) (2016) 0.75
Mutation of a heterothallic strain to homothallism. Genetics (1975) 4.09
Macromolecule synthesis and breakdown in relation to sporulation and meiosis in yeast. J Bacteriol (1974) 4.07
A yeast mutant which accumulates precursor tRNAs. Cell (1978) 3.57
Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes. Proc Natl Acad Sci U S A (1993) 3.24
Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes. Proc Natl Acad Sci U S A (1993) 2.46
Transcription in yeast: separation and properties of multiple FNA polymerases. Proc Natl Acad Sci U S A (1972) 2.45
Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import. J Cell Biol (1995) 2.43
Mating type and sporulation in yeast. I. Mutations which alter mating-type control over sporulation. Genetics (1975) 2.41
tRNA nuclear export in saccharomyces cerevisiae: in situ hybridization analysis. Mol Biol Cell (1998) 2.40
Multiple NF-kappaB enhancer elements regulate cytokine induction of the human inducible nitric oxide synthase gene. J Biol Chem (1998) 2.35
Nucleotide sequence of the tcml gene (ribosomal protein L3) of Saccharomyces cerevisiae. J Bacteriol (1983) 2.05
Nuclear tRNA aminoacylation and its role in nuclear export of endogenous tRNAs in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1999) 2.05
Cloning and characterization of LOS1, a Saccharomyces cerevisiae gene that affects tRNA splicing. Mol Cell Biol (1987) 2.00
Maf1p, a negative effector of RNA polymerase III in Saccharomyces cerevisiae. Mol Cell Biol (2001) 1.89
Structural and functional analyses of Saccharomyces cerevisiae wild-type and mutant RNA1 genes. Mol Cell Biol (1989) 1.85
Regulation of mRNA export in response to stress in Saccharomyces cerevisiae. Genes Dev (1996) 1.80
Isolation and characterization of the TRM1 locus, a gene essential for the N2,N2-dimethylguanosine modification of both mitochondrial and cytoplasmic tRNA in Saccharomyces cerevisiae. J Biol Chem (1986) 1.71
Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter. Proc Natl Acad Sci U S A (1996) 1.71
Isolation and characterization of MOD5, a gene required for isopentenylation of cytoplasmic and mitochondrial tRNAs of Saccharomyces cerevisiae. Mol Cell Biol (1987) 1.67
RRP1, a Saccharomyces cerevisiae gene affecting rRNA processing and production of mature ribosomal subunits. J Bacteriol (1987) 1.65
Protein synthesis in relation to sporulation and meiosis in yeast. J Bacteriol (1974) 1.62
Transcriptional role of yeast deoxyribonucleic acid dependent ribonucleic acid polymerase III. Biochemistry (1978) 1.57
Defects in modification of cytoplasmic and mitochondrial transfer RNAs are caused by single nuclear mutations. Cell (1982) 1.55
Mating type and sporulation in yeast. II. Meiosis, recombination, and radiation sensitivity in an alpha-alpha diploid with altered sporulation control. Genetics (1975) 1.54
Vaccination with yeast-expressed cottontail rabbit papillomavirus (CRPV) virus-like particles protects rabbits from CRPV-induced papilloma formation. Vaccine (1995) 1.53
DNA sequence and transcript mapping of MOD5: features of the 5' region which suggest two translational starts. Mol Cell Biol (1987) 1.48
MOD5 translation initiation sites determine N6-isopentenyladenosine modification of mitochondrial and cytoplasmic tRNA. Mol Cell Biol (1991) 1.44
Molecular characterisation of the tyrosine tRNA genes of yeast. Nature (1977) 1.44
mRNA leader length and initiation codon context determine alternative AUG selection for the yeast gene MOD5. Proc Natl Acad Sci U S A (1991) 1.44
Role of nuclear pools of aminoacyl-tRNA synthetases in tRNA nuclear export. Mol Biol Cell (2001) 1.43
Sequence determination of human papillomavirus type 6a and assembly of virus-like particles in Saccharomyces cerevisiae. Virology (1995) 1.43
Transcription in yeast: alpha-amanitin sensitivity and other properties which distinguish between RNA polymerases I and III. Proc Natl Acad Sci U S A (1976) 1.42
MDP1, a Saccharomyces cerevisiae gene involved in mitochondrial/cytoplasmic protein distribution, is identical to the ubiquitin-protein ligase gene RSP5. Genetics (1997) 1.41
Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes. Gastroenterology (2001) 1.40
Periorbital melanocytic lesions: excision and reconstruction in 40 patients. Plast Reconstr Surg (1998) 1.38
Characterization of an essential Saccharomyces cerevisiae gene related to RNA processing: cloning of RNA1 and generation of a new allele with a novel phenotype. Mol Cell Biol (1985) 1.36
Nitric oxide down-regulates hepatocyte-inducible nitric oxide synthase gene expression. Arch Surg (1997) 1.34
SRN1, a yeast gene involved in RNA processing, is identical to HEX2/REG1, a negative regulator in glucose repression. Mol Cell Biol (1992) 1.33
Actin-binding verprolin is a polarity development protein required for the morphogenesis and function of the yeast actin cytoskeleton. J Cell Biol (1997) 1.33
A central role for IL-1 beta in the in vitro and in vivo regulation of hepatic inducible nitric oxide synthase. IL-1 beta induces hepatic nitric oxide synthesis. J Immunol (1995) 1.33
Estrogen receptor (ER)alpha and ERbeta exhibit unique pharmacologic properties when coupled to activation of the mitogen-activated protein kinase pathway. Endocrinology (2001) 1.31
A yeast mutant defective in the processing of 27S r-RNA precursor. Mol Gen Genet (1976) 1.30
Defects in tRNA processing and nuclear export induce GCN4 translation independently of phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. Mol Cell Biol (2000) 1.29
Vaccine prophylaxis of abattoir-associated Q fever: eight years' experience in Australian abattoirs. Epidemiol Infect (1990) 1.28
N2,N2-dimethylguanosine-specific tRNA methyltransferase contains both nuclear and mitochondrial targeting signals in Saccharomyces cerevisiae. J Cell Biol (1989) 1.27
TAP1, a yeast gene that activates the expression of a tRNA gene with a defective internal promoter. Mol Cell Biol (1993) 1.27
Mutations altering the mitochondrial-cytoplasmic distribution of Mod5p implicate the actin cytoskeleton and mRNA 3' ends and/or protein synthesis in mitochondrial delivery. Mol Cell Biol (1995) 1.26
Isolation of a yeast gene involved in species-specific pre-tRNA processing. Mol Cell Biol (1988) 1.25
The Saccharomyces cerevisiae LOS1 gene involved in pre-tRNA splicing encodes a nuclear protein that behaves as a component of the nuclear matrix. J Biol Chem (1993) 1.23
Purification of virus-like particles of recombinant human papillomavirus type 11 major capsid protein L1 from Saccharomyces cerevisiae. Protein Expr Purif (1999) 1.21
Human papillomavirus type 11 (HPV-11) neutralizing antibodies in the serum and genital mucosal secretions of African green monkeys immunized with HPV-11 virus-like particles expressed in yeast. J Infect Dis (1997) 1.20
tRNA synthesis: identification of in vivo precursor tRNAs from parental and mutant yeast strains. Nucleic Acids Res (1981) 1.19
Saccharomyces cerevisiae Mod5p-II contains sequences antagonistic for nuclear and cytosolic locations. Genetics (1999) 1.19
Porphyromonas gingivalis lipopolysaccharide is poorly recognized by molecular components of innate host defense in a mouse model of early inflammation. Infect Immun (1995) 1.16
Inactivation of rat renal phosphate-dependent glutaminase with 6-diazo-5-oxo-L-norleucine. Evidence for interaction at the glutamine binding site. J Biol Chem (1979) 1.16
How single genes provide tRNA processing enzymes to mitochondria, nuclei and the cytosol. Biochimie (1994) 1.16
Antagonistic effects of NES and NLS motifs determine S. cerevisiae Rna1p subcellular distribution. J Cell Sci (1999) 1.14
Differential induction of nitric oxide synthase in hepatocytes during endotoxemia and the acute-phase response. Arch Surg (1994) 1.14
Location of N2,N2-dimethylguanosine-specific tRNA methyltransferase. Biochimie (1995) 1.13
WW domains of Rsp5p define different functions: determination of roles in fluid phase and uracil permease endocytosis in Saccharomyces cerevisiae. Genetics (2001) 1.12
CD14 employs hydrophilic regions to "capture" lipopolysaccharides. J Immunol (2000) 1.11
Subcellular locations of MOD5 proteins: mapping of sequences sufficient for targeting to mitochondria and demonstration that mitochondrial and nuclear isoforms commingle in the cytosol. Mol Cell Biol (1994) 1.10
Expression of CD14 by hepatocytes: upregulation by cytokines during endotoxemia. Infect Immun (1998) 1.09
Nitric-oxide production by murine mammary adenocarcinoma cells promotes tumor-cell invasiveness. Int J Cancer (1999) 1.08
Isopentenylation of both cytoplasmic and mitochondrial tRNA is affected by a single nuclear mutation. J Biol Chem (1982) 1.08
Amino-terminal extension generated from an upstream AUG codon is not required for mitochondrial import of yeast N2,N2-dimethylguanosine-specific tRNA methyltransferase. Proc Natl Acad Sci U S A (1987) 1.08
Site-directed mutagenesis of glycosylation sites in the transforming growth factor-beta 1 (TGF beta 1) and TGF beta 2 (414) precursors and of cysteine residues within mature TGF beta 1: effects on secretion and bioactivity. Mol Endocrinol (1992) 1.08
Cause and clinical characteristics of rib fractures in infants. Pediatrics (2000) 1.08
Mechanisms leading to and the consequences of altering the normal distribution of ATP(CTP):tRNA nucleotidyltransferase in yeast. J Biol Chem (1996) 1.06
Competition between a sterol biosynthetic enzyme and tRNA modification in addition to changes in the protein synthesis machinery causes altered nonsense suppression. Proc Natl Acad Sci U S A (2000) 1.05
Division of labor among the yeast Sol proteins implicated in tRNA nuclear export and carbohydrate metabolism. Genetics (2004) 1.04
In vitro RNA synthesis in oocyte nuclei of the newt Notophthalmus. Chromosoma (1981) 1.03
Estrogen induces rapid translocation of estrogen receptor beta, but not estrogen receptor alpha, to the neuronal plasma membrane. Neuroscience (2008) 1.03
STP1, a gene involved in pre-tRNA processing, encodes a nuclear protein containing zinc finger motifs. Mol Cell Biol (1992) 1.02
Molecular cloning, characterization, and tissue distribution of rat lipopolysaccharide binding protein. Evidence for extrahepatic expression. J Immunol (1994) 1.02
Amino-terminal extension generated from an upstream AUG codon increases the efficiency of mitochondrial import of yeast N2,N2-dimethylguanosine-specific tRNA methyltransferases. Mol Cell Biol (1989) 1.02
Genetic methods for study of trans-acting genes involved in processing of precursors to yeast cytoplasmic transfer RNAs. Methods Enzymol (1990) 1.01
Noise in the operating room. N Engl J Med (1972) 1.01
Dexamethasone suppresses iNOS gene expression by upregulating I-kappa B alpha and inhibiting NF-kappa B. Am J Physiol (1997) 1.01
Covalent interaction of L-2-amino-4-oxo-5-chloropentanoic acid with rat renal phosphate-dependent glutaminase. Evidence for a specific glutamate binding site and of subunit heterogeneity. J Biol Chem (1978) 1.00
SRD1, a S. cerevisiae gene affecting pre-rRNA processing contains a C2/C2 zinc finger motif. Nucleic Acids Res (1994) 1.00
Separate information required for nuclear and subnuclear localization: additional complexity in localizing an enzyme shared by mitochondria and nuclei. Mol Cell Biol (1992) 0.99
The human WASP-interacting protein, WIP, activates the cell polarity pathway in yeast. J Biol Chem (1999) 0.98
Comparison of the phosphate-dependent glutaminase obtained from rat brain and kidney. Biochem J (1985) 0.97
ADEPTs: information necessary for subcellular distribution of eukaryotic sorting isozymes resides in domains missing from eubacterial and archaeal counterparts. Nucleic Acids Res (2000) 0.96
Nitric oxide synthase expression is induced in hepatocytes in vivo during hepatic inflammation. J Surg Res (1993) 0.96
Occurrence and distribution of interdental gingival clefts following orthodontic movement into bicuspid extraction sites. J Periodontol (1977) 0.95
Cytokine induction of interferon regulatory factor-1 in hepatocytes. Surgery (1993) 0.95
The glucose repression and RAS-cAMP signal transduction pathways of Saccharomyces cerevisiae each affect RNA processing and the synthesis of a reporter protein. Mol Gen Genet (1995) 0.94
The orientation of phosphate-dependent glutaminase on the inner membrane of rat renal mitochondria. Arch Biochem Biophys (1985) 0.94
Los1p, involved in yeast pre-tRNA splicing, positively regulates members of the SOL gene family. Genetics (1996) 0.92
Cloning of the cDNA and expression of moubatin, an inhibitor of platelet aggregation. J Biol Chem (1993) 0.92
maf1 mutation alters the subcellular localization of the Mod5 protein in yeast. Acta Biochim Pol (1994) 0.92
The prevalence of sexually transmitted diseases in children and adolescents evaluated for sexual abuse in Cincinnati: rationale for limited STD testing in prepubertal girls. Pediatrics (1995) 0.92
srd1, a Saccharomyces cerevisiae suppressor of the temperature-sensitive pre-rRNA processing defect of rrp1-1. Genetics (1990) 0.91
Mechanism of altered renal glutaminase gene expression in response to chronic acidosis. Biochemistry (1991) 0.91
Interplay of heterogeneous transcriptional start sites and translational selection of AUGs dictate the production of mitochondrial and cytosolic/nuclear tRNA nucleotidyltransferase from the same gene in yeast. J Biol Chem (1994) 0.89
Characterization of rat CD14 promoter and its regulation by transcription factors AP1 and Sp family proteins in hepatocytes. Gene (2000) 0.89
Isolation of a cDNA for rat brain glutaminase. Brain Res (1988) 0.89
The utilization of the alpha-glycerophosphate and monoglyceride pathways for phosphatidyl choline biosynthesis in the intestine. Biochim Biophys Acta (1970) 0.89