Published in J Mol Biol on November 25, 1978
Molecular evidence for genetic exchanges among ribosomal genes on nonhomologous chromosomes in man and apes. Proc Natl Acad Sci U S A (1980) 3.92
Human nucleolus organizers on nonhomologous chromosomes can share the same ribosomal gene variants. Proc Natl Acad Sci U S A (1981) 3.21
Human ribosomal RNA gene arrays display a broad range of palindromic structures. Genome Res (2005) 1.33
Nucleotide sequence of a complete ribosomal spacer of D. melanogaster. Nucleic Acids Res (1985) 1.32
Linkage disequilibrium in human ribosomal genes: implications for multigene family evolution. Genetics (1988) 1.24
HeLa cell identification by analysis of ribosomal DNA segment patterns generated by endonuclease restriction. Am J Hum Genet (1980) 1.23
Genomic organization of rat rDNA. Nucleic Acids Res (1983) 1.22
Evolutionary changes of sequences and factors that direct transcription termination of human and mouse ribsomal genes. Mol Cell Biol (1987) 1.20
Structure and variation of human ribosomal DNA: the external transcribed spacer and adjacent regions. Am J Hum Genet (1982) 1.19
A molecular basis for discrete size variation in human ribosomal DNA. Am J Hum Genet (1985) 1.12
Extraordinary ribosomal spacer length heterogeneity in a neotyphodium endophyte hybrid: implications for concerted evolution. Genetics (1998) 1.04
New tandem repeat region in the non-transcribed spacer of human ribosomal RNA gene. Nucleic Acids Res (1989) 1.02
Small nuclear RNAs are encoded in the nontranscribed region of ribosomal spacer DNA. Proc Natl Acad Sci U S A (1982) 0.91
Heterogeneity of pumpkin ribosomal DNA. Plant Physiol (1983) 0.87
Studies of the inheritance of human ribosomal DNA variants detected in two-dimensional separations of genomic restriction fragments. Genetics (1996) 0.85
Organization of ribosomal genes in Paramecium tetraurelia. J Cell Biol (1980) 0.83
Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science (1985) 95.08
Amplification, expression, and packaging of foreign gene by influenza virus. Cell (1989) 11.21
Amplification and analysis of DNA sequences in single human sperm and diploid cells. Nature (1988) 10.84
Length mutations in human mitochondrial DNA: direct sequencing of enzymatically amplified DNA. Nucleic Acids Res (1987) 10.38
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell (1988) 10.29
Whole genome amplification from a single cell: implications for genetic analysis. Proc Natl Acad Sci U S A (1992) 9.15
Detection of human papilloma virus in paraffin-embedded tissue using the polymerase chain reaction. J Exp Med (1988) 9.10
Introduction of site-specific mutations into the genome of influenza virus. Proc Natl Acad Sci U S A (1990) 7.68
A simple method for site-directed mutagenesis using the polymerase chain reaction. Nucleic Acids Res (1989) 6.78
A member of a new repeated sequence family which is conserved throughout eucaryotic evolution is found between the human delta and beta globin genes. Nucleic Acids Res (1981) 6.70
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over. Nat Genet (1996) 6.06
Promoter analysis of influenza virus RNA polymerase. J Virol (1989) 5.66
Heterogeneity of the ribosomal genes in mice and men. Cell (1977) 5.36
Evolution of human influenza A viruses over 50 years: rapid, uniform rate of change in NS gene. Science (1986) 4.64
5' flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains. Cell (1980) 4.62
Determination of influenza virus proteins required for genome replication. J Virol (1990) 4.36
Genomic RNAs of influenza viruses are held in a circular conformation in virions and in infected cells by a terminal panhandle. Proc Natl Acad Sci U S A (1987) 4.31
Influenza B virus evolution: co-circulating lineages and comparison of evolutionary pattern with those of influenza A and C viruses. Virology (1988) 4.03
The polymerase chain reaction. Trends Genet (1989) 3.95
Molecular evidence for genetic exchanges among ribosomal genes on nonhomologous chromosomes in man and apes. Proc Natl Acad Sci U S A (1980) 3.92
Rescue of a foreign gene by Sendai virus. Proc Natl Acad Sci U S A (1991) 3.85
Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR. Nucleic Acids Res (1992) 3.74
Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons. Neuron (1998) 3.72
Detection of cytomegalovirus DNA in peripheral blood of patients infected with human immunodeficiency virus. J Infect Dis (1988) 3.52
Single-sperm typing: determination of genetic distance between the G gamma-globin and parathyroid hormone loci by using the polymerase chain reaction and allele-specific oligomers. Proc Natl Acad Sci U S A (1989) 3.50
Rapid prenatal diagnosis of sickle cell anemia by a new method of DNA analysis. N Engl J Med (1987) 3.44
Sequence-specific binding of the influenza virus RNA polymerase to sequences located at the 5' ends of the viral RNAs. J Virol (1994) 3.41
Recombinant influenza virus polymerase: requirement of both 5' and 3' viral ends for endonuclease activity. J Virol (1994) 3.39
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. Cell (1995) 3.34
Human nucleolus organizers on nonhomologous chromosomes can share the same ribosomal gene variants. Proc Natl Acad Sci U S A (1981) 3.21
Detection of a specific mitochondrial DNA deletion in tissues of older humans. Nucleic Acids Res (1990) 3.13
The evolutionarily conserved repetitive sequence d(TG.AC)n promotes reciprocal exchange and generates unusual recombinant tetrads during yeast meiosis. Mol Cell Biol (1986) 2.86
Evolution of influenza A and B viruses: conservation of structural features in the hemagglutinin genes. Proc Natl Acad Sci U S A (1982) 2.86
A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues. Proc Natl Acad Sci U S A (1992) 2.83
Distribution of ribosomal gene length variants among mouse chromosomes. Proc Natl Acad Sci U S A (1982) 2.66
Species-specific rDNA transcription is due to promoter-specific binding factors. Mol Cell Biol (1984) 2.51
A multiple-tubes approach for accurate genotyping of very small DNA samples by using PCR: statistical considerations. Am J Hum Genet (1992) 2.42
Two nuclear location signals in the influenza virus NS1 nonstructural protein. J Virol (1988) 2.34
Direct electrophoretic detection of the allelic state of single DNA molecules in human sperm by using the polymerase chain reaction. Proc Natl Acad Sci U S A (1990) 2.33
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair. Nat Genet (1998) 2.32
Use of pooled DNA samples to detect linkage disequilibrium of polymorphic restriction fragments and human disease: studies of the HLA class II loci. Proc Natl Acad Sci U S A (1985) 2.19
Using PCR in preimplantation genetic disease diagnosis. Hum Reprod (1991) 2.18
Differential activation of the influenza virus polymerase via template RNA binding. J Virol (1995) 2.18
Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain. Nat Genet (1992) 2.16
New HLA-DPB1 alleles generated by interallelic gene conversion detected by analysis of sperm. Nat Genet (1995) 2.14
Hydroxylated quantum dots as luminescent probes for in situ hybridization. J Am Chem Soc (2001) 2.12
Identification of the in vivo and in vitro origin of transcription in human rDNA. Nucleic Acids Res (1982) 2.11
Analysis of DNA sequences in forty-year-old paraffin-embedded thin-tissue sections: a bridge between molecular biology and classical histology. Cancer Res (1988) 2.06
Genetic analysis using the polymerase chain reaction. Annu Rev Genet (1992) 2.06
Bacteriophage T7 lysozyme is an N-acetylmuramyl-L-alanine amidase. J Biol Chem (1973) 1.92
Structure and organization of the highly repeated and interspersed 1.3 kb EcoRI-Bg1II sequence family in mice. Nucleic Acids Res (1980) 1.89
Sequential mutations in hemagglutinins of influenza B virus isolates: definition of antigenic domains. Proc Natl Acad Sci U S A (1983) 1.88
Fine-structure genetic mapping of human chromosomes using the polymerase chain reaction on single sperm: experimental design considerations. Am J Hum Genet (1989) 1.83
Triplet repeats form secondary structures that escape DNA repair in yeast. Proc Natl Acad Sci U S A (1999) 1.83
Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm. Proc Natl Acad Sci U S A (2006) 1.80
Multipoint linkage map of the human pseudoautosomal region, based on single-sperm typing: do double crossovers occur during male meiosis? Am J Hum Genet (1994) 1.78
The genetic behaviour of a cloned mouse ribosomal DNA segment mimics mouse ribosomal gene evolution. J Mol Biol (1979) 1.75
Mouse rDNA nontranscribed spacer sequences are found flanking immunoglobulin CH genes and elsewhere throughout the genome. Cell (1980) 1.74
Evidence for heterogeneity in recombination in the human pseudoautosomal region: high resolution analysis by sperm typing and radiation-hybrid mapping. Am J Hum Genet (2000) 1.74
Comparison of the three large polymerase proteins of influenza A, B, and C viruses. Virology (1989) 1.72
Ordering three DNA polymorphisms on human chromosome 3 by sperm typing. Genomics (1991) 1.69
Infectious influenza A and B virus variants with long carboxyl terminal deletions in the NS1 polypeptides. Virology (1987) 1.68
Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export. Mol Cell Biol (2000) 1.64
Characterization of mouse ribosomal gene fragments purified by molecular cloning. Gene (1979) 1.64
Recombination hot spot in the human beta-globin gene cluster: meiotic recombination of human DNA fragments in Saccharomyces cerevisiae. Mol Cell Biol (1985) 1.63
Transient reversion of ras oncogene-induced cell transformation by antibodies specific for amino acid 12 of ras protein. Nature (1985) 1.61
The influenza C virus glycoprotein (HE) exhibits receptor-binding (hemagglutinin) and receptor-destroying (esterase) activities. Virology (1987) 1.59
Stability of intrastrand hairpin structures formed by the CAG/CTG class of DNA triplet repeats associated with neurological diseases. Nucleic Acids Res (1996) 1.59
Purification and molecular structure of RNA polymerase from influenza virus A/PR8. J Biochem (1990) 1.57
Expression of influenza virus NS2 nonstructural protein in bacteria and localization of NS2 in infected eucaryotic cells. J Virol (1985) 1.55
Nucleotide sequence of the genetically labile repeated elements 5' to the origin of mouse rRNA transcription. Nucleic Acids Res (1983) 1.50
Detection of human papillomavirus in normal and dysplastic tissue by the polymerase chain reaction. Lab Invest (1988) 1.48
Noncumulative sequence changes in the hemagglutinin genes of influenza C virus isolates. Virology (1985) 1.48
Studying human mutations by sperm typing: instability of CAG trinucleotide repeats in the human androgen receptor gene. Nat Genet (1994) 1.45
Sequential mutations in the NS genes of influenza virus field strains. J Virol (1983) 1.44
Immunological prediction of sequence differences among proteins. Chemical comparison of chicken, quail, and phesant lysozymes. J Biol Chem (1969) 1.43
Analysis of an influenza A virus mutant with a deletion in the NS segment. J Virol (1984) 1.42
Analysis of germline mutation spectra at the Huntington's disease locus supports a mitotic mutation mechanism. Hum Mol Genet (1999) 1.41
Mitochondrial DNA polymorphism: evidence that variants detected by restriction enzymes differ in nucleotide sequence rather than in methylation. Proc Natl Acad Sci U S A (1980) 1.40
Incomplete dosage compensation in an evolving Drosophila sex chromosome. Proc Natl Acad Sci U S A (1978) 1.40
Detection of human papillomavirus in formalin-fixed, invasive squamous carcinomas using the polymerase chain reaction. Am J Surg Pathol (1989) 1.40
Complementation and analysis of an NP mutant of influenza virus. Virus Res (1989) 1.38
Overexpression of the influenza virus polymerase can titrate out inhibition by the murine Mx1 protein. J Virol (1992) 1.36
Complete nucleotide sequence of the influenza C/California/78 virus nucleoprotein gene. Virus Res (1984) 1.32
High resolution localization of recombination hot spots using sperm typing. Nat Genet (1994) 1.32
Different mutator phenotypes in Mlh1- versus Pms2-deficient mice. Proc Natl Acad Sci U S A (1999) 1.32
Detection of c-K-ras mutations in fine needle aspirates from human pancreatic adenocarcinomas. Cancer Res (1990) 1.31
DNase I-hypersensitive sites and transcription factor-binding motifs within the mouse E beta meiotic recombination hot spot. Mol Cell Biol (1991) 1.31
Human immunodeficiency viral DNA is readily found in lymph node biopsies from seropositive individuals. Analysis of fixed tissue using the polymerase chain reaction. Am J Pathol (1989) 1.31
Influenza C virus hemagglutinin: comparison with influenza A and B virus hemagglutinins. J Virol (1984) 1.28
Biochemical studies on capped RNA primers identify a class of oligonucleotide inhibitors of the influenza virus RNA polymerase. Proc Natl Acad Sci U S A (1994) 1.27
Linkage disequilibrium in human ribosomal genes: implications for multigene family evolution. Genetics (1988) 1.24
Inhibition of the influenza virus RNA-dependent RNA polymerase by antisera directed against the carboxy-terminal region of the PB2 subunit. J Gen Virol (1996) 1.24
Close linkage between bovine prolactin and BoLA-DRB3 genes: genetic mapping in cattle by single sperm typing. Genomics (1992) 1.22
Base mispair extension kinetics. Binding of avian myeloblastosis reverse transcriptase to matched and mismatched base pair termini. J Biol Chem (1992) 1.22
Individual variation in recombination among human males. Am J Hum Genet (1996) 1.22
Unequal exchange at the Charcot-Marie-Tooth disease type 1A recombination hot-spot is not elevated above the genome average rate. Hum Mol Genet (2000) 1.21