Published in Biorheology on January 01, 1980
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Extensive restriction site polymorphism at the human phenylalanine hydroxylase locus and application in prenatal diagnosis of phenylketonuria. Am J Hum Genet (1985) 3.77
Complete sequence of the cDNA for human alpha 1-antitrypsin and the gene for the S variant. Biochemistry (1984) 3.75
Tight linkage between a splicing mutation and a specific DNA haplotype in phenylketonuria. Nature (1986) 3.29
The carpal tunnel syndrome. A study of carpal canal pressures. J Bone Joint Surg Am (1981) 3.16
Assessment of recombinant adenoviral vectors for hepatic gene therapy. Hum Gene Ther (1993) 3.02
Cloned human phenylalanine hydroxylase gene allows prenatal diagnosis and carrier detection of classical phenylketonuria. Nature (1984) 2.82
Polymorphic DNA haplotypes at the human phenylalanine hydroxylase locus and their relationship with phenylketonuria. Hum Genet (1987) 2.73
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Complete nucleotide sequence of the chicken chromosomal ovalbumin gene and its biological significance. Biochemistry (1981) 2.67
Screening for phenylketonuria mutations by DNA amplification with the polymerase chain reaction. Lancet (1988) 2.67
Regional mapping of the phenylalanine hydroxylase gene and the phenylketonuria locus in the human genome. Proc Natl Acad Sci U S A (1985) 2.58
The ovalbumin gene: alleles created by mutations in the intervening sequences of the natural gene. Cell (1979) 2.56
A sensitive and rapid method for recombinant phage screening. Methods Enzymol (1979) 2.52
Molecular structure and polymorphic map of the human phenylalanine hydroxylase gene. Biochemistry (1986) 2.49
Preparation and preliminary characterization of purified ovalbumin messenger RNA from the hen oviduct. Biochemistry (1975) 2.42
An amino-acid substitution involved in phenylketonuria is in linkage disequilibrium with DNA haplotype 2. Nature (1987) 2.37
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The importance of quadriceps and hamstring muscle loading on knee kinematics and in-situ forces in the ACL. J Biomech (1999) 2.31
Physical and chemical characterization of purified ovalbumin messenger RNA. J Biol Chem (1975) 2.28
Definition of 5' and 3' structural boundaries of the chromatin domain containing the ovalbumin multigene family. J Biol Chem (1982) 2.22
Mouse hepatocytes migrate to liver parenchyma and function indefinitely after intrasplenic transplantation. Proc Natl Acad Sci U S A (1991) 2.19
Influences of flexor sheath continuity and early motion on tendon healing in dogs. J Hand Surg Am (1990) 2.14
A frameshift mutation results in a truncated alpha 1-antitrypsin that is retained within the rough endoplasmic reticulum. J Biol Chem (1988) 2.11
The synthesis and properties of the complete complementary DNA transcript of ovalbumin mRNA. Biochemistry (1976) 2.08
DNA restriction fragments associated with alpha 1-antitrypsin indicate a single origin for deficiency allele PI Z. Nature (1985) 2.03
The chick ovomucoid gene contains at least six intervening sequences. Nature (1979) 2.01
A new method for determining cross-sectional shape and area of soft tissues. J Biomech Eng (1988) 1.96
The wick catheter technique for measurement of intramuscular pressure. A new research and clinical tool. J Bone Joint Surg Am (1976) 1.96
A curriculum for the ideal orthopaedic residency. Academic Orthopaedic Society. Clin Orthop Relat Res (1997) 1.94
Role of surgical decompression in treatment of rattlesnake bites. Surg Forum (1979) 1.94
Hepatic gene therapy: persistent expression of human alpha 1-antitrypsin in mice after direct gene delivery in vivo. Hum Gene Ther (1992) 1.92
Assignment of the alpha 1-antitrypsin gene and a sequence-related gene to human chromosome 14 by molecular hybridization. Am J Hum Genet (1983) 1.91
Cloning and sequence of cDNA coding for alpha 1-antitrypsin. Proc Natl Acad Sci U S A (1981) 1.91
The development of mature gait. J Bone Joint Surg Am (1980) 1.91
Effects of postmortem storage by freezing on ligament tensile behavior. J Biomech (1986) 1.89
Nascent chicken ovalbumin contains the functional equivalent of a signal sequence. J Cell Biol (1978) 1.88
GT to AT transition at a splice donor site causes skipping of the preceding exon in phenylketonuria. Nucleic Acids Res (1987) 1.86
Polymerase chain reaction amplification from dried blood spots on Guthrie cards. Lancet (1990) 1.86
Effects of immobilization on joints. Clin Orthop Relat Res (1987) 1.84
Hepatitis B virus transactivator X protein is not tumorigenic in transgenic mice. J Virol (1990) 1.80
The natural ovalbumin gene contains seven intervening sequences. Nature (1978) 1.79
Identification of multiple species of calmodulin messenger RNA using a full length complementary DNA. J Biol Chem (1983) 1.79
Intramuscular pressures with limb compression clarification of the pathogenesis of the drug-induced muscle-compartment syndrome. N Engl J Med (1979) 1.78
Ovalbumin is synthesized in mouse cells transformed with the natural chicken ovalbumin gene. Proc Natl Acad Sci U S A (1980) 1.77
Tendons and ligaments: a morphological and biochemical comparison. J Orthop Res (1984) 1.75
Accumulation of PiZ alpha 1-antitrypsin causes liver damage in transgenic mice. J Clin Invest (1989) 1.72
Sequence homology and structural comparison between the chromosomal human alpha 1-antitrypsin and chicken ovalbumin genes. Nature (1982) 1.70
Polysome immunoprecipitation of phenylalanine hydroxylase mRNA from rat liver and cloning of its cDNA. Proc Natl Acad Sci U S A (1982) 1.69
Molecular cloning of ovomucoid gene sequences from partially purified ovomucoid messenger RNA. Biochemistry (1978) 1.67
Regulation of casein messenger RNA during the development of the rat mammary gland. Biochemistry (1975) 1.66
Prenatal diagnosis of classic phenylketonuria by DNA analysis. Lancet (1985) 1.64
Chitinase gene expression during mycoparasitic interaction of Trichoderma harzianum with its host. Fungal Genet Biol (1999) 1.64
Nonlinear material properties of intact cornea and sclera. Exp Eye Res (1972) 1.63
Characterization of a model of osteoarthritis in the rabbit knee. Osteoarthritis Cartilage (1996) 1.62
The ovalbumin gene: cloning and molecular organization of the entire natural gene. Proc Natl Acad Sci U S A (1979) 1.61
Full-length cDNA for rabbit tryptophan hydroxylase: functional domains and evolution of aromatic amino acid hydroxylases. Proc Natl Acad Sci U S A (1987) 1.59
DNA sequence for cloned cDNA for murine amelogenin reveal the amino acid sequence for enamel-specific protein. Biochem Biophys Res Commun (1985) 1.57
Isolation and sequence characterization of a cDNA clone of human antithrombin III. Proc Natl Acad Sci U S A (1983) 1.56
In situ forces in the anterior cruciate ligament and its bundles in response to anterior tibial loads. J Orthop Res (1997) 1.55
Cloning large segments of genomic DNA using cosmid vectors. Methods Enzymol (1987) 1.55
Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis. Arthritis Rheum (1998) 1.52
Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice. Nucleic Acids Res (1987) 1.51
Phenylalanine hydroxylase deficiency caused by a single base substitution in an exon of the human phenylalanine hydroxylase gene. Biochemistry (1988) 1.50
Point mutagenesis of the ovalbumin gene promoter sequence and its effect on in vitro transcription. J Biol Chem (1982) 1.50
Effects of early intermittent passive mobilization on healing canine flexor tendons. J Hand Surg Am (1982) 1.50
Gene therapy for phenylketonuria: phenotypic correction in a genetically deficient mouse model by adenovirus-mediated hepatic gene transfer. Gene Ther (1994) 1.50
Genes from mycoparasitic fungi as a source for improving plant resistance to fungal pathogens. Proc Natl Acad Sci U S A (1998) 1.50
The forces in the anterior cruciate ligament and knee kinematics during a simulated pivot shift test: A human cadaveric study using robotic technology. Arthroscopy (2000) 1.49
Tensile and viscoelastic properties of human patellar tendon. J Orthop Res (1994) 1.49
Hamstrings--an anterior cruciate ligament protagonist. An in vitro study. Am J Sports Med (1993) 1.48
Importance of the medial meniscus in the anterior cruciate ligament-deficient knee. J Orthop Res (2000) 1.47
Gene transfer and expression of human phenylalanine hydroxylase. Science (1985) 1.46
Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo. Proc Natl Acad Sci U S A (1994) 1.46
The repair of large osteochondral defects. An experimental study in horses. Clin Orthop Relat Res (1972) 1.46
The biomechanical and biochemical properties of swine tendons--long term effects of exercise on the digital extensors. Connect Tissue Res (1980) 1.46
Reduction of skeletal muscle necrosis using intermittent hyperbaric oxygen in a model compartment syndrome. J Bone Joint Surg Am (1983) 1.45
Articular cartilage transplantation. Clinical results in the knee. Clin Orthop Relat Res (1999) 1.45
Collation of RFLP haplotypes at the human phenylalanine hydroxylase (PAH) locus. Am J Hum Genet (1988) 1.45
A functional comparison of animal anterior cruciate ligament models to the human anterior cruciate ligament. Ann Biomed Eng (1998) 1.45
Missense mutations associated with RFLP haplotypes 1 and 4 of the human phenylalanine hydroxylase gene. Am J Hum Genet (1990) 1.45
Therapeutic serum concentrations of human alpha-1-antitrypsin after adenoviral-mediated gene transfer into mouse hepatocytes. Hepatology (1995) 1.44
Ovalbumin gene. Action of restriction endonucleases upon DNA coding sequence. J Biol Chem (1977) 1.44
Retroviral gene transfer into primary hepatocytes: implications for genetic therapy of liver-specific functions. Proc Natl Acad Sci U S A (1987) 1.44
Sequence homology between human alpha 1-antichymotrypsin, alpha 1-antitrypsin, and antithrombin III. Biochemistry (1983) 1.43
The PKU locus in man is on chromosome 12. Am J Hum Genet (1984) 1.42
Adenovirus-mediated gene transfer of endostatin in vivo results in high level of transgene expression and inhibition of tumor growth and metastases. Proc Natl Acad Sci U S A (2000) 1.42
The ovalbumin gene: structural sequences in native chicken DNA are not contiguous. Proc Natl Acad Sci U S A (1978) 1.42
The phenomenon of "ligamentization": anterior cruciate ligament reconstruction with autogenous patellar tendon. J Orthop Res (1986) 1.42