Published in Am J Pathol on December 01, 1980
Normal genetically mosaic mice produced from malignant teratocarcinoma cells. Proc Natl Acad Sci U S A (1975) 7.27
Development of a strain of spontaneously hypertensive rats. Jpn Circ J (1963) 6.20
Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia (1978) 5.21
Streptozotocin-induced pancreatic insulitis: new model of diabetes mellitus. Science (1976) 4.08
Effects of parabiosis of obese with diabetes and normal mice. Diabetologia (1973) 3.16
Totipotency and normal differentiation of single teratocarcinoma cells cloned by injection into blastocysts. Proc Natl Acad Sci U S A (1976) 3.12
The influence of genetic background on the expression of the obese (Ob) gene in the mouse. Diabetologia (1973) 2.83
Effects of chronia excess salt ingestion. Evidence that genetic factors play an important role in susceptibility to experimental hypertension. J Exp Med (1962) 2.75
The spontaneously diabetic Wistar rat. Metabolic and morphologic studies. Diabetes (1977) 2.70
Studies of streptozotocin-induced insulitis and diabetes. Proc Natl Acad Sci U S A (1977) 1.94
Laboratory animals exhibiting obesity and diabetes syndromes. Metabolism (1977) 1.93
The spontaneously diabetic Wistar rat (the "BB" rat). Studies prior to and during development of the overt syndrome. Diabetologia (1978) 1.79
Mosaic mice with teratocarcinoma-derived mutant cells deficient in hypoxanthine phosphoribosyltransferase. Proc Natl Acad Sci U S A (1977) 1.66
Complete protection from low-dose streptozotocin-induced diabetes in mice. Nature (1978) 1.45
The New Zealand strain of rats with genetic hypertension. N Z Med J (1968) 1.45
Animal models--a neglected medical resource. N Engl J Med (1969) 1.43
Teratocarcinoma cells as vehicles for introducing specific mutant mitochondrial genes into mice. Proc Natl Acad Sci U S A (1978) 1.23
Streptozotocin-induced pancreatic insulitis in mice. Morphologic and physiologic studies. Lab Invest (1978) 1.21
Genetic influence of the streptozotocin-induced insulitis and hyperglycemia. Diabetes (1977) 1.16
Studies on streptozotocin diabetes. Diabetes (1976) 1.16
Perinatal behavior of northern elephant seal females and their young. Behaviour (1972) 1.13
Humoral transmission of hypertension: evidence from parabiosis. Circ Res (1969) 1.10
Obesity genes: beneficial effects in heterozygous mice. Science (1979) 1.08
Metabolism of bears before, during, and after winter sleep. Am J Physiol (1973) 1.07
Spontaneous diabetes in the gnotobiotic BB/W rat. Diabetes (1979) 1.01
Symposium IV: Diabetic syndrome in animals. Influence of genetic background on the expression of mutations at the diabetes locus in the mouse. II. Studies on background modifiers. Isr J Med Sci (1975) 0.99
Sex differences in the multiple-dose streptozotocin model of diabetes. Endocrinology (1978) 0.98
DIABETES MELLITUS IN THE SAND RAT INDUCED BY STANDARD LABORATORY DIETS. Science (1964) 0.90
Renal micropuncture study of normotensive and Milan hypertensive rats before and after development of hypertension. Kidney Int (1978) 0.90
Karyotypic normalcy and quasi-normalcy of developmentally totipotent mouse teratocarcinoma cells. Dev Biol (1978) 0.88
Viral studies in streptozotocin-induced pancreatic insulitis. Diabetologia (1978) 0.88
Characterization of Chinese hamsters by metabolic balance, glucose tolerance and insulin secretion. Diabetologia (1974) 0.87
The development of a new strain of spontaneously hypertensive rats. Life Sci (1974) 0.86
Animal models of diabetes and obesity, including the PBB/Ld mouse. Fed Proc (1976) 0.85
Acetone metabolism in mice: increased activity in mice heterozygous for obesity genes. Proc Natl Acad Sci U S A (1980) 0.84
EXPERIMENTAL DIABETES MELLITUS INDUCED BY DIET IN THE SAND RAT. Am J Physiol (1965) 0.80
Genetic and autonomic factors in inherited hypertension. Circ Res (1970) 0.78
Studies on the prediction and development of diabetes in offspring of diabetic Chinese hamsters. Diabetologia (1970) 0.77
Epidemiology of Chinese hamsters and preliminary evidence for genetic heterogeneity of diabetes. Diabetologia (1974) 0.76
Brain metabolism during fasting. J Clin Invest (1967) 6.48
Hormone-fuel interrelationships during fasting. J Clin Invest (1966) 6.44
Plasma amino acid levels and insulin secretion in obesity. N Engl J Med (1969) 4.18
Editorial: "Control" and diabetes. N Engl J Med (1976) 4.11
Amino acid metabolism during prolonged starvation. J Clin Invest (1969) 4.06
Starvation in man. N Engl J Med (1970) 3.67
Liver and kidney metabolism during prolonged starvation. J Clin Invest (1969) 3.47
Alanine: key role in gluconeogenesis. Science (1970) 3.43
Amino acid balance across tissues of the forearm in postabsorptive man. Effects of insulin at two dose levels. J Clin Invest (1969) 2.94
Renal gluconeogenesis in acidosis, alkalosis, and potassium deficiency: its possible role in regulation of renal ammonia production. J Clin Invest (1966) 2.64
Glucagon levels and metabolic effects in fasting man. J Clin Invest (1970) 2.58
Muscle and splanchnic glutmine and glutamate metabolism in postabsorptive andstarved man. J Clin Invest (1971) 2.10
Ketone bodies, potential therapeutic uses. IUBMB Life (2001) 1.98
Studies of streptozotocin-induced insulitis and diabetes. Proc Natl Acad Sci U S A (1977) 1.94
Insulin-dependent diabetes mellitus: the initial lesion. N Engl J Med (1981) 1.93
The Banting Memorial Lecture 1971. Physiology of insulin in man. Diabetes (1971) 1.68
Metabolic interactions of glucose, lactate, and beta-hydroxybutyrate in rat brain slices. Am J Physiol (1969) 1.56
Acid-base alterations and renal gluconeogenesis: effect of pH, bicarbonate concentration, and PCO2. J Clin Invest (1967) 1.55
Amino acid metabolism in lactic acidosis. Am J Med (1972) 1.26
Starvation in man. Clin Endocrinol Metab (1976) 1.24
Pancreatic beta cell toxicity by streptozotocin anomers. Diabetes (1977) 1.20
Amino acid metabolism in the regulation of gluconeogenesis in man. Am J Clin Nutr (1970) 1.11
Diffusion of glucose, insulin, inulin, and Evans blue protein into thoracic duct lymph of man. J Clin Invest (1967) 1.10
Starvation and survival. Trans Am Clin Climatol Assoc (1968) 1.09
Heterogeneity in type II diabetes. West J Med (1985) 1.08
Effect of insulin on muscle glutamate uptake. Whole blood versus plasma glutamate analysis. J Clin Invest (1972) 1.07
Studies on the perfused rat liver. I. Effects of glucagon and insulin on glucose metabolism. Diabetes (1966) 1.07
"A non-editorial on non-hypoglycemia". N Engl J Med (1974) 1.04
Hepatic glucose phosphototransferases. Variations among species. Diabetes (1966) 1.02
Blood cell and plasma amino acid levels across forearm muscle during a protein meal. Diabetes (1973) 1.02
Metabolic response to human growth hormone during prolonged starvation. J Clin Invest (1971) 1.01
Effects of insulin in the toadfish, Opsanus tau. Gen Comp Endocrinol (1968) 0.97
Ketosis. Kidney Int (1981) 0.96
Effect of acid-base status on renal and hepatic gluconeogenesis in diabetes and fasting. Am J Physiol (1969) 0.96
Insulin blockade of amino acid release by human forearm tissues. Trans Assoc Am Physicians (1968) 0.95
The redox state and regulation of amino acid metabolism in man. Biochem Soc Symp (1978) 0.95
Amino acid levels across normal forearm muscle and splanchnic bed after a protein meal. Am J Clin Nutr (1976) 0.94
Metabolic effects of exogenous glucocorticoids in fasted man. J Clin Invest (1973) 0.94
Studies on the perfused rat liver. II. Effect of glucagon on gluconeogenesis. Diabetes (1966) 0.93
Diabetes mellitus-an overview. Curr Concepts Nutr (1981) 0.92
Brown and white adipose tissue metabolism response to norepinephrine and insulin. Am J Physiol (1966) 0.91
Insulin and muscle amino acid balance. Proc Nutr Soc (1972) 0.90
Are plasma amino acid levels elevated in obesity? N Engl J Med (1970) 0.89
Metabolic effects of glucose in brief and prolonged fasted man. Am J Clin Nutr (1975) 0.89
Starvation and body nitrogen. Trans Am Clin Climatol Assoc (1971) 0.89
Glucagon. N Engl J Med (1973) 0.89
Metabolic and endocrine studies in a case of lipoatrophic diabetes. Metabolism (1977) 0.89
Blood glucose and cluconeogenesis in fasting man. Arch Intern Med (1969) 0.88
Renal gluconeogenesis and amino-acid metabolism in man. Med Clin North Am (1975) 0.88
Survival in starvation. Am J Clin Nutr (1998) 0.87
Practical developments in diabetes research. Diabetes (1972) 0.87
Current concepts of diabetic complications with emphasis on hereditary factors: a brief review. Prog Clin Biol Res (1979) 0.86
Ketosis. Trans Am Clin Climatol Assoc (1973) 0.86
Hormone-fuel concentrations in anephric subjects. Effect of hemodialysis (with special reference to amino acids). J Clin Invest (1976) 0.86
Obesity and insulin levels. N Engl J Med (1971) 0.85
Effect of alanine and glycine on glucagon secretion in postabsorptive and fasting obese man. J Clin Endocrinol Metab (1975) 0.84
Hormonal regulation of glutamine metabolism in fasting man. Adv Enzyme Regul (1972) 0.84
Role of substrate in the regulation of hepatic gluconeogenesis in fasting man. Adv Enzyme Regul (1969) 0.83
Selective effect of insulin on glucose-U-C14 metabolism in rabbit liver slices. Am J Physiol (1965) 0.83
Utilization of metabolic fuels in obese subjects. Am J Clin Nutr (1968) 0.83
Effects of exogenous insulin on the rate of fatty acid synthesis and glucose C-14 utilization in the twenty-day rat fetus. Diabetes (1968) 0.81
Glucogenic substrate levels in fasting man. Adv Enzyme Regul (1975) 0.81
Beta-cell deficiency, insulin resistance, or both? N Engl J Med (1988) 0.81
Amino acid levels across normal forearm muscle: whole blood vs. plasma. Adv Enzyme Regul (1974) 0.81
Effects of exogenous glucagon and epinephrine in physiological amounts on the blood levels of free fatty acids and glycerol in dogs. Diabetologia (1977) 0.81
Protein and amino acid metabolism in man. Circ Res (1976) 0.80
Beta cell protection to alloxan necrosis by anomers of D-glucose. Science (1974) 0.80
Studies of alloxan toxicity on the beta cell. Diabetes (1975) 0.80
Metabolic memory. N Engl J Med (1980) 0.80
Studies on experimental diabetes in the Wellesley hybrid mouse. II. Serum insulin levels and response of peripheral tissues. Diabetologia (1967) 0.80
Acute ketotic-type diabetic syndrome in sand rats (Psammomys obesus) with special reference to the pancreas. Metabolism (1966) 0.79
Alanine-induced amino acid interrelationships. Metabolism (1975) 0.79
Effects of beta-hydroxybutyrate, glycerol, and free fatty acid infusions on glucagon and epinephrine secretion in dogs during acute hypoglycemia. Metabolism (1976) 0.79
C-peptide: a new method of assessing pancreatic beta-cell function. N Engl J Med (1973) 0.78
Caveat on fluid replacement in hyperglycemic, hyperosmolar, nonketotic coma. Diabetes Care (1979) 0.78
How metabolism affects clinical problems. Med Times (1970) 0.78
Plasma and cerebrosponal fluid amino acid levels in diabetic ketoacidosis before and after corrective therapy. Diabetes (1975) 0.78
Effect of glucagon on amino acid and nitrogen metabolism in fasting man. Metabolism (1974) 0.78
Insulin and proinsulin. N Engl J Med (1970) 0.78
Hyperglycemic hyperosmolar coma: a syndrome almost unique to the elderly. J Am Geriatr Soc (1983) 0.77
Gonadotropin profiles in fed and fasted obese women. Am J Obstet Gynecol (1979) 0.77
Role of T3 in fasted man. Life Sci (1981) 0.77
President's address. Starvation. Trans Am Clin Climatol Assoc (1983) 0.77
Insulin and fuel homeostasis. Physiologist (1968) 0.76
Diabetes mellitus--progress report. Prog Clin Biol Res (1976) 0.76
Anomeric specificty of 3-0-methyl-D-glycopyranose against alloxan diabetes. Science (1975) 0.76
Human evolution and insulin-dependent (IDD) and non-insulin dependent diabetes (NIDD). Metabolism (1979) 0.76
Thayer lecture. Diabetes mellitus: a brief overview. Johns Hopkins Med J (1978) 0.76
Diabetes mellitus: progress and directions. Am J Med (1981) 0.76
Paraneoplastic syndromes. Hyperglycemia. Ann N Y Acad Sci (1974) 0.75
Memorial. Edgar Stillwell Gordon. Trans Am Clin Climatol Assoc (1977) 0.75
Diabetes and evolution: some speculations. Del Med J (1978) 0.75
"Health" steak. N Engl J Med (1973) 0.75
Some observations on hypoglycemia in man. Adv Enzyme Regul (1964) 0.75
1969 diabetes detection campaign. N Engl J Med (1969) 0.75
The diabetic pancreas. N Engl J Med (1978) 0.75
Prenatal nutrition of lambs, bears--and babies? Pediatrics (1972) 0.75
Mechanisms of protein sparing in carbohydrate loaded man. Surg Forum (1979) 0.75
Studies using the intraperitoneal assay on the state of insulin in rat serum. Metabolism (1966) 0.75
Assay of crystalline insulin and of serum insulin-like activity of different species on adipose tissue of the rat, mouse and guinea pig. N Engl J Med (1965) 0.75