Synthetic RNA-cleaving molecules mimicking ribonuclease A active center. Design and cleavage of tRNA transcripts.

PubWeight™: 0.91‹?›

🔗 View Article (PMC 310480)

Published in Nucleic Acids Res on December 25, 1993

Authors

M A Podyminogin1, V V Vlassov, R Giegé

Author Affiliations

1: UPR Structure des Macromolécules Biologiques et Mécanismes de Reconnaissance, Institut de Biologie Moléculaire et Cellulaire du CNRS, Strasbourg, France.

Articles cited by this

Mapping adenines, guanines, and pyrimidines in RNA. Nucleic Acids Res (1977) 26.63

Probing the structure of RNAs in solution. Nucleic Acids Res (1987) 7.62

The three-dimensional structure of ribonuclease-S. Interpretation of an electron density map at a nominal resolution of 2 A. J Biol Chem (1970) 2.77

Conformation in solution of yeast tRNA(Asp) transcripts deprived of modified nucleotides. Biochimie (1990) 1.97

Yeast tRNAAsp tertiary structure in solution and areas of interaction of the tRNA with aspartyl-tRNA synthetase. A comparative study of the yeast phenylalanine system by phosphate alkylation experiments with ethylnitrosourea. J Mol Biol (1985) 1.94

Pb(II)-catalysed cleavage of the sugar-phosphate backbone of yeast tRNAPhe--implications for lead toxicity and self-splicing RNA. Nature (1983) 1.92

Lead-catalyzed cleavage of yeast tRNAPhe mutants. Biochemistry (1990) 1.87

The tRNA-like structure of turnip yellow mosaic virus RNA: structural organization of the last 159 nucleotides from the 3' OH terminus. EMBO J (1982) 1.73

The refined crystal structure of ribonuclease A at 2.0 A resolution. J Biol Chem (1982) 1.58

Tertiary structure of tRNAs in solution monitored by phosphodiester modification with ethylnitrosourea. Eur J Biochem (1981) 1.56

Characterization of the lead(II)-induced cleavages in tRNAs in solution and effect of the Y-base removal in yeast tRNAPhe. Biochemistry (1988) 1.53

Partial digestion of tRNA--aminoacyl-tRNA synthetase complexes with cobra venom ribonuclease. Biochemistry (1981) 1.52

Chemical nucleases: new reagents in molecular biology. Annu Rev Biochem (1990) 1.42

Nonenzymatic hydrolysis of oligoribonucleotides. Nucleic Acids Res (1992) 1.29

Conformational changes and dynamics of tRNAs: evidence from hydrolysis patterns. Cold Spring Harb Symp Quant Biol (1987) 1.23

Specific cleavages of pure tRNAs by plumbous ions. Biochim Biophys Acta (1976) 1.22

Structure of aspartate-tRNA from brewer's yeast. Nat New Biol (1971) 1.05

Design of peptide-acridine mimics of ribonuclease activity. Proc Natl Acad Sci U S A (1992) 1.04

New photoactivatable structural and affinity probes of RNAs: specific features and applications for mapping of spermine binding sites in yeast tRNA(Asp) and interaction of this tRNA with yeast aspartyl-tRNA synthetase. Nucleic Acids Res (1990) 1.00

Articles by these authors

An operational RNA code for amino acids and possible relationship to genetic code. Proc Natl Acad Sci U S A (1993) 2.87

Search for characteristic structural features of mammalian mitochondrial tRNAs. RNA (2000) 2.84

Crystal structure of yeast tRNAAsp. Nature (1980) 2.61

Identity elements for specific aminoacylation of yeast tRNA(Asp) by cognate aspartyl-tRNA synthetase. Science (1991) 2.48

Relaxation of a transfer RNA specificity by removal of modified nucleotides. Nature (1990) 2.20

Mechanism of oligonucleotide uptake by cells: involvement of specific receptors? Proc Natl Acad Sci U S A (1989) 1.97

Conformation in solution of yeast tRNA(Asp) transcripts deprived of modified nucleotides. Biochimie (1990) 1.97

Yeast tRNAAsp tertiary structure in solution and areas of interaction of the tRNA with aspartyl-tRNA synthetase. A comparative study of the yeast phenylalanine system by phosphate alkylation experiments with ethylnitrosourea. J Mol Biol (1985) 1.94

The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA. Nucleic Acids Res (1998) 1.92

Complementary-addressed (sequence-specific) modification of nucleic acids. Prog Nucleic Acid Res Mol Biol (1985) 1.87

A Watson-Crick base-pair-disrupting methyl group (m1A9) is sufficient for cloverleaf folding of human mitochondrial tRNALys. Biochemistry (1999) 1.79

Health care, medical practice, and medical ethics in Russia today. JAMA (1995) 1.76

Molecular recognition of the identity-determinant set of isoleucine transfer RNA from Escherichia coli. J Mol Biol (1994) 1.68

Ribozyme processed tRNA transcripts with unfriendly internal promoter for T7 RNA polymerase: production and activity. FEBS Lett (1998) 1.63

More mistakes by T7 RNA polymerase at the 5' ends of in vitro-transcribed RNAs. RNA (1999) 1.61

Tertiary structure of tRNAs in solution monitored by phosphodiester modification with ethylnitrosourea. Eur J Biochem (1981) 1.56

Factors determining the specificity of the tRNA aminoacylation reaction. Non-absolute specificity of tRNA-aminoacyl-tRNA synthetase recognition and particular importance of the maximal velocity. Biochimie (1973) 1.56

Aminoacylated tmRNA from Escherichia coli interacts with prokaryotic elongation factor Tu. RNA (1999) 1.55

Characterization of the lead(II)-induced cleavages in tRNAs in solution and effect of the Y-base removal in yeast tRNAPhe. Biochemistry (1988) 1.53

Comparison of the tertiary structure of yeast tRNA(Asp) and tRNA(Phe) in solution. Chemical modification study of the bases. J Mol Biol (1987) 1.50

An unusual RNA tertiary interaction has a role for the specific aminoacylation of a transfer RNA. Proc Natl Acad Sci U S A (1993) 1.47

Solution structure of a tRNA with a large variable region: yeast tRNASer. J Mol Biol (1989) 1.47

Histidylation by yeast HisRS of tRNA or tRNA-like structure relies on residues -1 and 73 but is dependent on the RNA context. Nucleic Acids Res (1994) 1.44

Solution structure of the 3'-end of brome mosaic virus genomic RNAs. Conformational mimicry with canonical tRNAs. J Mol Biol (1994) 1.44

Structure of tetragonal hen egg-white lysozyme at 0.94 A from crystals grown by the counter-diffusion method. Acta Crystallogr D Biol Crystallogr (2001) 1.42

Enzymatic formation of modified nucleosides in tRNA: dependence on tRNA architecture. J Mol Biol (1996) 1.41

Effect of modified nucleotides on Escherichia coli tRNAGlu structure and on its aminoacylation by glutamyl-tRNA synthetase. Predominant and distinct roles of the mnm5 and s2 modifications of U34. Eur J Biochem (1999) 1.40

The 2.0 A crystal structure of Thermus thermophilus methionyl-tRNA synthetase reveals two RNA-binding modules. Structure (2000) 1.40

Antideterminants present in minihelix(Sec) hinder its recognition by prokaryotic elongation factor Tu. EMBO J (1996) 1.40

A single methyl group prevents the mischarging of a tRNA. Nat Struct Biol (1994) 1.37

Synthesis of alkylating oligonucleotide derivatives containing cholesterol or phenazinium residues at their 3'-terminus and their interaction with DNA within mammalian cells. FEBS Lett (1989) 1.35

Cationic lipid-DNA complexes-lipoplexes-for gene transfer and therapy. Bioelectrochemistry (2002) 1.35

A domain in the N-terminal extension of class IIb eukaryotic aminoacyl-tRNA synthetases is important for tRNA binding. EMBO J (2000) 1.34

3-D graphics modelling of the tRNA-like 3'-end of turnip yellow mosaic virus RNA: structural and functional implications. J Biomol Struct Dyn (1987) 1.33

Cell-free and cell-bound circulating DNA in breast tumours: DNA quantification and analysis of tumour-related gene methylation. Br J Cancer (2006) 1.32

Novel features in the tRNA-like world of plant viral RNAs. Cell Mol Life Sci (2001) 1.29

Anticodon-independent aminoacylation of an RNA minihelix with valine. Proc Natl Acad Sci U S A (1992) 1.26

Importance of conserved residues for the conformation of the T-loop in tRNAs. J Biomol Struct Dyn (1987) 1.23

Additive, cooperative and anti-cooperative effects between identity nucleotides of a tRNA. EMBO J (1993) 1.22

Efficient aminoacylation of resected RNA helices by class II aspartyl-tRNA synthetase dependent on a single nucleotide. EMBO J (1994) 1.20

Incorrect aminoacylatins catalysed by the phenylalanyl-and valyl-tRNA synthetases from yeast. Eur J Biochem (1972) 1.18

Solution structure of selenocysteine-inserting tRNA(Sec) from Escherichia coli. Comparison with canonical tRNA(Ser). J Mol Biol (1993) 1.17

Dynamic light scattering studies of the aggregation of lysozyme under crystallization conditions. FEBS Lett (1991) 1.17

Specific valylation of turnip yellow mosaic virus RNA by wheat germ valyl-tRNA synthetase determined by three anticodon loop nucleotides. Biochemistry (1992) 1.16

Diagnostic of precipitant for biomacromolecule crystallization by quasi-elastic light-scattering. J Mol Biol (1990) 1.14

Determinant nucleotides of yeast tRNA(Asp) interact directly with aspartyl-tRNA synthetase. Proc Natl Acad Sci U S A (1992) 1.14

Cleavage of tRNA with imidazole and spermine imidazole constructs: a new approach for probing RNA structure. Nucleic Acids Res (1995) 1.13

Existence of two distinct aspartyl-tRNA synthetases in Thermus thermophilus. Structural and biochemical properties of the two enzymes. Biochemistry (1997) 1.13

Interaction of tRNAPhe and tRNAVal with aminoacyl-tRNA synthetases. A chemical modification study. Eur J Biochem (1983) 1.13

Identity of prokaryotic and eukaryotic tRNA(Asp) for aminoacylation by aspartyl-tRNA synthetase from Thermus thermophilus. Biochemistry (1996) 1.13

Identity of tRNA for yeast tyrosyl-tRNA synthetase: tyrosylation is more sensitive to identity nucleotides than to structural features. Biochemistry (2000) 1.11

Large scale purification and structural properties of yeast aspartyl-tRNA synthetase. Biochem Biophys Res Commun (1983) 1.11

Interpretation of tRNA-mischarging kinetics. Eur J Biochem (1976) 1.11

Anticodon-anticodon interaction induces conformational changes in tRNA: yeast tRNAAsp, a model for tRNA-mRNA recognition. Proc Natl Acad Sci U S A (1986) 1.11

A central pseudoknotted three-way junction imposes tRNA-like mimicry and the orientation of three 5' upstream pseudoknots in the 3' terminus of tobacco mosaic virus RNA. RNA (1996) 1.10

Influence of tRNA tertiary structure and stability on aminoacylation by yeast aspartyl-tRNA synthetase. Nucleic Acids Res (1993) 1.10

Effect of conformational features on the aminoacylation of tRNAs and consequences on the permutation of tRNA specificities. J Mol Biol (1992) 1.10

The contacts of yeast tRNA(Ser) with seryl-tRNA synthetase studied by footprinting experiments. Eur J Biochem (1990) 1.10

Arginine aminoacylation identity is context-dependent and ensured by alternate recognition sets in the anticodon loop of accepting tRNA transcripts. EMBO J (1996) 1.09

Identity elements of tRNA(Trp). Identification and evolutionary conservation. J Biol Chem (1993) 1.09

The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain. J Mol Biol (2000) 1.08

Glycyl-tRNA synthetase from Thermus thermophilus--wide structural divergence with other prokaryotic glycyl-tRNA synthetases and functional inter-relation with prokaryotic and eukaryotic glycylation systems. Eur J Biochem (1998) 1.08

Experimental determination of water equilibration rates in the hanging drop method of protein crystallization. Anal Biochem (1990) 1.08

trans-Diamminedichloroplatinum(II), a reversible RNA-protein cross-linking agent. Application to the ribosome and to an aminoacyl-tRNA synthetase/tRNA complex. Biochemistry (1987) 1.07

Raman spectra and structure of yeast phenylalanine transfer RNA in the crystalline state and in solution. Biochemistry (1975) 1.07

Nucleotide and oligonucleotide derivatives as enzyme and nucleic acid targeted irreversible inhibitors. Chemical aspects. Adv Enzyme Regul (1985) 1.06

Valylation of the two RNA components of turnip-yellow mosaic virus and specificity of the tRNA aminoacylation reaction. Eur J Biochem (1978) 1.06

Structure of phenylalanine-accepting transfer ribonucleic acid and of its environment in aqueous solvents with different salts. Biochemistry (1983) 1.05

Magnesium-dependent alternative foldings of active and inactive Escherichia coli tRNA(Glu) revealed by chemical probing. Nucleic Acids Res (1999) 1.05

Strategy for RNA recognition by yeast histidyl-tRNA synthetase. Bioorg Med Chem (1997) 1.04

Efficient mischarging of a viral tRNA-like structure and aminoacylation of a minihelix containing a pseudoknot: histidinylation of turnip yellow mosaic virus RNA. Nucleic Acids Res (1992) 1.03

Studies on anticodon-anticodon interactions: hemi-protonation of cytosines induces self-pairing through the GCC anticodon of E. coli tRNA-Gly. J Biomol Struct Dyn (1986) 1.03

Formylation of mischarged E. coli tRNA Met f . FEBS Lett (1973) 1.02

A histidine accepting tRNA-like fold at the 3'-end of satellite tobacco mosaic virus RNA. Nucleic Acids Res (1994) 1.02

Tertiary structure of animal tRNATrp in solution and interaction of tRNATrp with tryptophanyl-tRNA synthetase. Eur J Biochem (1984) 1.02

Incorrect aminoacylations involving tRNAs or valyl-tRNA synthetase from Bacillus stearothermophilus. Eur J Biochem (1974) 1.02

Interactions between avian myeloblastosis reverse transcriptase and tRNATrp. Mapping of complexed tRNA with chemicals and nucleases. Nucleic Acids Res (1984) 1.01

New photoactivatable structural and affinity probes of RNAs: specific features and applications for mapping of spermine binding sites in yeast tRNA(Asp) and interaction of this tRNA with yeast aspartyl-tRNA synthetase. Nucleic Acids Res (1990) 1.00

The structure of yeast tRNA(Asp). A model for tRNA interacting with messenger RNA. J Biomol Struct Dyn (1985) 0.99

Effect of a mutation in the anticodon of human mitochondrial tRNAPro on its post-transcriptional modification pattern. Nucleic Acids Res (1998) 0.99

Triple aminoacylation specificity of a chimerized transfer RNA. Biochemistry (1993) 0.99

Isoleucylation properties of native human mitochondrial tRNAIle and tRNAIle transcripts. Implications for cardiomyopathy-related point mutations (4269, 4317) in the tRNAIle gene. Hum Mol Genet (1998) 0.98

Characterisation of membrane oligonucleotide-binding proteins and oligonucleotide uptake in keratinocytes. Nucleic Acids Res (1999) 0.98

The yeast aminoacyl-tRNA synthetases. Methodology for their complete or partial purification and comparison of their relative activities under various extraction conditions. Biochimie (1977) 0.98

Complementary addressed modification and cleavage of a single stranded DNA fragment with alkylating oligonucleotide derivatives. Nucleic Acids Res (1986) 0.98

Mirror image alternative interaction patterns of the same tRNA with either class I arginyl-tRNA synthetase or class II aspartyl-tRNA synthetase. Nucleic Acids Res (1997) 0.97

Simultaneous binding of two proteins to opposite sides of a single transfer RNA. Nat Struct Biol (2001) 0.96

Identity switches between tRNAs aminoacylated by class I glutaminyl- and class II aspartyl-tRNA synthetases. Biochemistry (1994) 0.96

Solution conformation of several free tRNALeu species from bean, yeast and Escherichia coli and interaction of these tRNAs with bean cytoplasmic Leucyl-tRNA synthetase. A phosphate alkylation study with ethylnitrosourea. Nucleic Acids Res (1990) 0.96

Three photo-cross-linked complexes of yeast phenylalanine specific transfer ribonucleic acid with aminoacyl transfer ribonucleic acid synthetases. J Biol Chem (1975) 0.96

RNase T1 mimicking artificial ribonuclease. Nucleic Acids Res (2007) 0.95

Site-specific cleavage of single-stranded DNAs at unique sites by a copper-dependent redox reaction. Nature (1988) 0.95

Complete purification and studies on the structural and kinetic properties of two forms of yeast valyl-tRNA synthetase. Biochimie (1975) 0.95

Effect of elongation factor Tu on the conformation of phenylalanyl-tRNAPhe. FEBS Lett (1983) 0.93

Formation of a catalytically active complex between tRNAAsp and aspartyl-tRNA synthetase from yeast in high concentrations of ammonium sulphate. Biochimie (1982) 0.93

Crystal structure of yeast tRNAAsp: atomic coordinates. Biochimie (1985) 0.93

The plant tRNA 3' processing enzyme has a broad substrate spectrum. Biochemistry (2001) 0.92